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Aliases for FAM122A Gene

Aliases for FAM122A Gene

  • Family With Sequence Similarity 122A 2 3 5
  • C9orf42 3 4
  • Chromosome 9 Open Reading Frame 42 2

External Ids for FAM122A Gene

Previous HGNC Symbols for FAM122A Gene

  • C9orf42

Previous GeneCards Identifiers for FAM122A Gene

  • GC09P070584
  • GC09P071394
  • GC09P041240

Summaries for FAM122A Gene

GeneCards Summary for FAM122A Gene

FAM122A (Family With Sequence Similarity 122A) is a Protein Coding gene. An important paralog of this gene is FAM122C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM122A Gene

Genomics for FAM122A Gene

Regulatory Elements for FAM122A Gene

Enhancers for FAM122A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM122A on UCSC Golden Path with GeneCards custom track

Promoters for FAM122A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM122A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM122A Gene

Chromosome:
9
Start:
68,780,048 bp from pter
End:
68,784,608 bp from pter
Size:
4,561 bases
Orientation:
Plus strand

Genomic View for FAM122A Gene

Genes around FAM122A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM122A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM122A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM122A Gene

Proteins for FAM122A Gene

  • Protein details for FAM122A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96E09-F122A_HUMAN
    Recommended name:
    Protein FAM122A
    Protein Accession:
    Q96E09

    Protein attributes for FAM122A Gene

    Size:
    287 amino acids
    Molecular mass:
    30529 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM122A Gene

Proteomics data for FAM122A Gene at MOPED

Post-translational modifications for FAM122A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM122A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM122A Gene

Domains & Families for FAM122A Gene

Protein Domains for FAM122A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM122A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q96E09

UniProtKB/Swiss-Prot:

F122A_HUMAN :
  • Belongs to the FAM122 family.
Family:
  • Belongs to the FAM122 family.
genes like me logo Genes that share domains with FAM122A: view

No data available for Gene Families for FAM122A Gene

Function for FAM122A Gene

Phenotypes for FAM122A Gene

GenomeRNAi human phenotypes for FAM122A:
genes like me logo Genes that share phenotypes with FAM122A: view

Animal Model Products

CRISPR Products

miRNA for FAM122A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM122A Gene

Localization for FAM122A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM122A Gene COMPARTMENTS Subcellular localization image for FAM122A gene
Compartment Confidence
nucleus 3
cytosol 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM122A Gene

Pathways & Interactions for FAM122A Gene

SuperPathways for FAM122A Gene

No Data Available

Interacting Proteins for FAM122A Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000377807%0d%0a9606.ENSP00000300086%0d%0a9606.ENSP00000336591%0d%0a
Selected Interacting proteins: ENSP00000377807 Q96E09-F122A_HUMAN for FAM122A Gene via STRING UniProtKB I2D

Gene Ontology (GO) - Biological Process for FAM122A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM122A Gene

Drugs & Compounds for FAM122A Gene

No Compound Related Data Available

Transcripts for FAM122A Gene

mRNA/cDNA for FAM122A Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(130) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM122A Gene

Family with sequence similarity 122A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM122A Gene

No ASD Table

Relevant External Links for FAM122A Gene

GeneLoc Exon Structure for
FAM122A
ECgene alternative splicing isoforms for
FAM122A

Expression for FAM122A Gene

mRNA expression in normal human tissues for FAM122A Gene

Protein differential expression in normal tissues from HIPED for FAM122A Gene

This gene is overexpressed in Placenta (27.3), Pancreas (25.8), and CD8 Tcells (8.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MOPED, and MaxQB for FAM122A Gene



SOURCE GeneReport for Unigene cluster for FAM122A Gene Hs.655572

genes like me logo Genes that share expression patterns with FAM122A: view

Protein tissue co-expression partners for FAM122A Gene

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM122A Gene

Orthologs for FAM122A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM122A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM122A 35
  • 94.08 (n)
  • 97.56 (a)
FAM122A 36
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM122A 35
  • 94.19 (n)
  • 97.91 (a)
FAM122A 36
  • 98 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam122a 35
  • 91.08 (n)
  • 95.42 (a)
Fam122a 16
Fam122a 36
  • 98 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM122A 35
  • 99.54 (n)
  • 100 (a)
rat
(Rattus norvegicus)
Mammalia Fam122a 35
  • 92.66 (n)
  • 97.2 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 73 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 83 (a)
OneToMany
chicken
(Gallus gallus)
Aves FAM122A 35
  • 74.03 (n)
  • 71.74 (a)
FAM122A 36
  • 70 (a)
OneToMany
tropical clawed frog
(Silurana tropicalis)
Amphibia fam122a 35
  • 69.63 (n)
  • 72.22 (a)
zebrafish
(Danio rerio)
Actinopterygii fam122b 35
  • 66.29 (n)
  • 67.66 (a)
fam122b 36
  • 65 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG4497 36
  • 16 (a)
OneToMany
Species with no ortholog for FAM122A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM122A Gene

ENSEMBL:
Gene Tree for FAM122A (if available)
TreeFam:
Gene Tree for FAM122A (if available)

Paralogs for FAM122A Gene

Paralogs for FAM122A Gene

(4) SIMAP similar genes for FAM122A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM122A: view

Variants for FAM122A Gene

Structural Variations from Database of Genomic Variants (DGV) for FAM122A Gene

Variant ID Type Subtype PubMed ID
esv2422258 CNV Duplication 17116639

Variation tolerance for FAM122A Gene

Residual Variation Intolerance Score: 32.6% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.85; 17.85% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar and Relevant External Links for FAM122A Gene

Disorders for FAM122A Gene

Relevant External Links for FAM122A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM122A

No disorders were found for FAM122A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM122A Gene

Publications for FAM122A Gene

  1. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 67
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  4. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3
  5. A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning. (PMID: 26673895) KA+rlA+ K. … GAPrlich D. (Elife 2015) 3

Products for FAM122A Gene

Sources for FAM122A Gene

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