FAM120AOS Gene
protein-coding GIFtS: 38
GCID: GC09M096208
|
|
family with sequence similarity 120A opposite strand(Previous name: chromosome 9 open reading frame 10 opposite strand )
(Previous symbol: C9orf10OS)
| |
Aliases
for FAM120AOS gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 120A Opposite Strand1 2 | | C9orf10OS1 2 3 | | Chromosome 9 Open Reading Frame 10 Opposite Strand1 | | Putative FAM120A Opposite Strand Protein2 |
Export aliases for FAM120AOS gene to outside databasesPrevious GC identifers: GC09M095242 GC09M065886 |
Summaries
for FAM120AOS gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM120AOS gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000009.11 NC_018920.1 NT_008470.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM120AOS gene promoter:
Pax-5 NCX/Ncx GCNF HNF-4alpha2 NF-kappaB HNF-4alpha1 GCNF-1 GCNF-2 NF-kappaB1 RSRFC4
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM120AOS
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM120AOS |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 9q22.31 Ensembl cytogenetic band: 9q22.31 HGNC cytogenetic band: 9q22.32FAM120AOS Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 9 GeneLoc Exon Structure GeneLoc location for GC09M096208: view genomic region
(about GC identifiers)
Start:
|
96,208,776 bp from pter |
End:
|
96,215,874 bp from pter |
Size:
|
7,099 bases |
Orientation:
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minus strand |
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Proteins
for FAM120AOS gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F120S_HUMAN, Q5T036 (See
protein sequence)Recommended Name: Putative FAM120A opposite strand protein Size: 256 amino acids; 27929 Da
Caution: Product of a dubious gene prediction
Secondary accessions: A6NN20Explore the universe of human proteins at neXtProt for FAM120AOS: NX_Q5T036
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q5T036
FAM120AOS Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_942138.2
ENSEMBL proteins: ENSP00000414298 ENSP00000364561 ENSP00000429212 ENSP00000416978
Human Recombinant Protein Products:
FAM120AOS Antibody Products:
Assay Products for FAM120AOS: |
Protein
Domains /
Families
for FAM120AOS gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: Q5T036 |
Function
for FAM120AOS gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM120AOS
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM120AOS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: FAM120AOS (NM_198841) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM120AOS | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM120AOS |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM120AOS |
|
Pathways & Interactions
for FAM120AOS gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM120AOS
STRING Interaction
Network Preview (showing 1 interactants - click image to see more details)
1 Interacting protein for FAM120AOS (ENSP000003645614) via UniProtKB, MINT, STRING, and/or I2DAbout this table
|
Drugs & Compounds
for FAM120AOS gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM120AOS
Search CenterWatch for drugs/clinical trials and news about FAM120AOS / F120S
|
Transcripts
for FAM120AOS gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM120AOS gene: NM_198841.2 Unigene Clusters for FAM120AOS: Family with sequence similarity 120A opposite strand Hs.350364 [show with all ESTs], Hs.709859 [show with all ESTs]Unigene Representative Sequences: NM_198841, AK09364111 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000479094(uc004atn.4) ENST00000423591(uc004atp.4 uc004atq.4)
ENST00000375412(uc004ats.4 uc004att.4 uc004atu.4) ENST00000523407
ENST00000520403 ENST00000520470 ENST00000483149 ENST00000483056 ENST00000476484
ENST00000428152 ENST00000428378
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM120AOS
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM120AOS
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: FAM120AOS (NM_198841) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM120AOS | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM120AOS |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM120AOS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM120AOS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM120AOS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM120AOS |
Additional cDNA sequence: AK093641.1 BC015241.2 BC068089.1 16 DOTS entries: DT.100782234 DT.445599 DT.91939154 DT.97844655 DT.100027381 DT.95136928 DT.100844983 DT.121189003 DT.110215 DT.417217 DT.95279271 DT.100782235 DT.121189006 DT.449081 DT.95279304 DT.95279275 24/277 AceView cDNA sequences (see all 277): H86064 BM893650 AW028729 BM875358 CA448592 CK823248 AA973558 AA401521 BM966801 AW024466 BU159650 AI198510 BX113019 BC037551 BM969596 AI690123 AW005958 AI459080 AI819330 AA576833 N20137 AA633092 BG333216 BX501487
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FAM120AOS (see all 8) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | · | 6f |
|---|
|
| SP1: | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | |
| SP4: | | | - | | - | | - | | - | | - | | - | | | | | | - | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | - | | - | | | | | | - | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for FAM120AOS
|
Expression
for FAM120AOS gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM120AOS expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGGGCCTTC
About this image
See FAM120AOS Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM120AOS
SOURCE GeneReport for Unigene clusters: Hs.350364 Hs.709859
SABiosciences Custom PCR Arrays for FAM120AOS
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM120AOS
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat FAM120AOS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM120AOS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM120AOS | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM120AOS |
Orthologs
for FAM120AOS gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for FAM120AOS gene from 1 species (see representative species ) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Fam120aos5 |
RIKEN cDNA C030044B11 gene |
-- |
|
13 (25.04 cM) 48968112 |
ENSEMBL Gene Tree for FAM120AOS (if available)
TreeFam Gene Tree for FAM120AOS (if available) |
Paralogs
for FAM120AOS gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for FAM120AOS gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 9 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM120AOS (96208776 - 96215874 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM120AOS: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM120AOS |
|
Disorders
/ Diseases
for FAM120AOS gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for FAM120AOS gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM120AOS gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM120AOS) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. (PubMed id 14585507)1, 3 Holden S. and Raymond F.L. (2003)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
- DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)2 Humphray S.J.... Dunham I. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for FAM120AOS gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAM120AOS gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM120AOS gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM120AOS gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM120AOS | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM120AOS gene:
Search GeneIP for patents involving FAM120AOS
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM120AOS gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | Browse OriGene shRNA RFPs | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM120AOS | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM120AOS | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM120AOS | | OriGene 3'-UTR Clone for FAM120AOS | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM120AOS | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM120AOS | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM120AOS | | OriGene Custom Protein Services for FAM120AOS | | | OriGene Custom Immunoassay Development | | |
| |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM120AOS | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM120AOS | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM120AOS | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM120AOS | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM120AOS | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM120AOS |
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 | | | FAM120AOS Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM120AOS |
|  |  |  | | | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM120AOS |
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