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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAM120A Gene

protein-coding   GIFtS: 54
GCID: GC09P096214

Family With Sequence Similarity 120A

(Previous name: chromosome 9 open reading frame 10)
(Previous symbol: C9orf10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Family With Sequence Similarity 120A1 2     Chromosome 9 Open Reading Frame 101
C9orf101 2 3 5     DNAPTP12
DNA Polymerase-Transactivated Protein 11 2     DNAPTP52
Oxidative Stess-Associated Src Activator1 2     Constitutive Coactivator Of PPAR-Gamma-Like Protein 12
Oxidative Stress-Associated Src Activator2 3     DNA Polymerase-Transactivated Protein 52
OSSA2 3     Protein FAM120A3
KIAA01833 5     

External Ids:    HGNC: 132471   Entrez Gene: 231962   Ensembl: ENSG000000488287   OMIM: 6122655   UniProtKB: Q9NZB23   

Export aliases for FAM120A gene to outside databases

Previous GC identifers: GC09P095253 GC09P065891


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FAM120A Gene: 
FAM120A (family with sequence similarity 120A) is a protein-coding gene. Diseases associated with FAM120A include myiasis, and achondrogenesis. GO annotations related to this gene include RNA binding. An important paralog of this gene is FAM120C.

UniProtKB/Swiss-Prot: F120A_HUMAN, Q9NZB2
Function: May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative
stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src
family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play
a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in
environments with various oxidative stresses

Gene Wiki entry for FAM120A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008470.19  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAM120A gene promoter:
         Pax-5   GCNF   NCX/Ncx   HNF-4alpha2   NF-kappaB   HNF-4alpha1   GCNF-1   NF-kappaB1   GCNF-2   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM120A promoter sequence
   Search SABiosciences Chromatin IP Primers for FAM120A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM120A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q22.31   Ensembl cytogenetic band:  9q22.31   HGNC cytogenetic band: 9q22.31

FAM120A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM120A gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09P096214:  view genomic region     (about GC identifiers)

Start:
96,214,004 bp from pter      End:
96,328,397 bp from pter
Size:
114,394 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: F120A_HUMAN, Q9NZB2 (See protein sequence)
Recommended Name: Constitutive coactivator of PPAR-gamma-like protein 1  
Size: 1118 amino acids; 121888 Da
Subunit: Interacts with PURA (By similarity). Interacts with YES1, SRC, FYN. Upon tyrosine phosphorylation,
interacts with PIK3R1
Subcellular location: Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Translocates
to plasma membrane upon ultraviolet exposure
Sequence caution: Sequence=AAF72866.1; Type=Frameshift; Positions=1055;
Secondary accessions: A6NGU0 C4AMC6 O60649 Q14688 Q4VXF4 Q4VXF5 Q4VXG2 Q86V69 Q96I21 Q9NZB1
Alternative splicing: 5 isoforms:  Q9NZB2-1   Q9NZB2-2   Q9NZB2-4   Q9NZB2-5   Q9NZB2-6   

Explore the universe of human proteins at neXtProt for FAM120A: NX_Q9NZB2

Explore proteomics data for FAM120A at MOPED 

Post-translational modifications:

  • UniProtKB: Arg-982 is dimethylated, probably to asymmetric dimethylarginine
  • UniProtKB: Phosphorylated on tyrosine by src family kinases upon ultraviolet exposure
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9NZB2

  • FAM120A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FAM120A Protein Expression
    REFSEQ proteins: NP_055427.2  
    ENSEMBL proteins: 
     ENSP00000277165   ENSP00000364538   ENSP00000396534   ENSP00000412440   ENSP00000334918  
     ENSP00000344698  

    Human Recombinant Protein Products for FAM120A: 
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    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM120A 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005886plasma membrane IEA--

    FAM120A for ontologies           About GeneDecksing



    FAM120A Antibody Products: 
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    Cloud-Clone Corp. ELISAs for FAM120A 
    Cloud-Clone Corp. CLIAs for FAM120A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR026783 Coact_PPARg-like_1

    Graphical View of Domain Structure for InterPro Entry Q9NZB2

    ProtoNet protein and cluster: Q9NZB2

    UniProtKB/Swiss-Prot: F120A_HUMAN, Q9NZB2
    Similarity: Belongs to the constitutive coactivator of PPAR-gamma family


    FAM120A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: F120A_HUMAN, Q9NZB2
    Function: May participate in mRNA transport in the cytoplasm (By similarity). Critical component of the oxidative
    stress-induced survival signaling. Activates src family kinases and acts as a scaffolding protein enabling src
    family kinases to phosphorylate and activate PI3-kinase. Binds RNA and promotes the secretion of IGF-II. May play
    a pivotal role in the progression of scirrhous-type gastric cancer by supporting cancer cell survival in
    environments with various oxidative stresses

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003723RNA binding IEA--
         
    FAM120A for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for FAM120A:
     Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FAM120A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FAM120A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM120A 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM120A 

    miRNA
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    8/78 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM120A (see all 78):
    hsa-miR-579 hsa-miR-582-3p hsa-miR-298 hsa-miR-4325 hsa-miR-29a* hsa-miR-1298 hsa-miR-4289 hsa-miR-548b-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM120A 3' UTR sequence
    Inhib. RNA
    Products:
        
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    Gene Editing
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    Sirion Biotech Customized adenovirus for overexpression of FAM120A

    Clone
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM120A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM120A

    STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

    5/7 Interacting proteins for FAM120A (Q9NZB23 ENSP000002771654) via UniProtKB, MINT, STRING, and/or I2D (see all 7)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ESR2Q927313, ENSP000003439254I2D: score=1 STRING: ENSP00000343925
    BECN1Q144573, ENSP000003552314I2D: score=1 STRING: ENSP00000355231
    CFTRP135693I2D: score=1 
    PRKAA1Q131313I2D: score=1 
    KNCNENSP000003796074STRING: ENSP00000379607
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAM120A (F120A)

    Search CenterWatch for drugs/clinical trials and news about FAM120A / F120A

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FAM120A gene: 
    NM_014612.3  

    Unigene Clusters for FAM120A:

    Family with sequence similarity 120A
    Hs.372003  [show with all ESTs], Hs.738743  [show with all ESTs]
    Unigene Representative Sequences: BC075701, DN999950
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000277165 ENST00000375389(uc004atv.3) ENST00000446420(uc004atx.3)
    ENST00000475933 ENST00000427765 ENST00000333936(uc010mrf.1 uc004atw.3 uc004aty.3 uc004atz.3)
    ENST00000340893(uc010mrg.3)
    miRNA
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    8/78 QIAGEN miScript miRNA Assays for microRNAs that regulate FAM120A (see all 78):
    hsa-miR-579 hsa-miR-582-3p hsa-miR-298 hsa-miR-4325 hsa-miR-29a* hsa-miR-1298 hsa-miR-4289 hsa-miR-548b-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM120A 3' UTR sequence
    Inhib. RNA
    Products:
         
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM120A
    Clone
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    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM120A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM120A
    Sirion Biotech Customized lentivirus for stable overexpression of FAM120A 
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    OriGene qPCR primer pairs and template standards for FAM120A
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      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM120A

    Additional mRNA sequence: AY450389.1 

    19 DOTS entries:

    DT.449081  DT.97821255  DT.100845713  DT.99939997  DT.121188984  DT.100845711  DT.100845712  DT.100845710 
    DT.95120718  DT.121188936  DT.121188981  DT.95362449  DT.100845715  DT.219817  DT.91922414  DT.95362443 
    DT.40116330  DT.92013490  DT.95353600 

    24/564 AceView cDNA sequences (see all 564):

    BM970688 AI984561 BQ927110 BU528570 AA243428 BU628242 AI568701 BM799330 
    F04406 AW772115 AW273026 BQ775121 N36620 BC007879 BE464389 BE887613 
    BM997131 AA977443 AA805698 BM905127 AI088305 BM702946 BM931476 BQ233490 

    GeneLoc Exon Structure

    5/11 Alternative Splicing Database (ASD) splice patterns (SP) for FAM120A (see all 11)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c ^ 8a · 8b ^ 9a · 9b ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14a · 14b · 14c ^ 15 ^ 16a · 16b ^ 17 ^ 18 ^
    SP1:                                                                                                                                                            
    SP2:                                                                                      -                                               -     -               
    SP3:                                                                                                                                                            
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 19a · 19b
    SP1:            
    SP2:            
    SP3:            
    SP4:            
    SP5:            


    ECgene alternative splicing isoforms for FAM120A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAM120A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GATTGTGCAA
    FAM120A Expression
    About this image


    See FAM120A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FAM120A

    SOURCE GeneReport for Unigene clusters: Hs.372003 Hs.738743

    UniProtKB/Swiss-Prot: F120A_HUMAN, Q9NZB2
    Tissue specificity: Ubiquitously expressed. Highly expressed in scirrhous-type gastric cancer tissues compared
    with normal gastric mucosa (at protein level)

        SABiosciences Custom PCR Arrays for FAM120A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM120A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FAM120A gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam120a1 , 5 family with sequence similarity 120, member A1, 5 91.94(n)1
    96.94(a)1
      13 (25.00 cM)5
    2182361  NM_001033268.21  NP_001028440.21 
     488792165 
    chicken
    (Gallus gallus)
    Aves FAM120A1 family with sequence similarity 120A 85.41(n)
    91.35(a)
      415983  XM_414325.3  XP_414325.3 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    88(a)
    86(a)
    many → 1
    many → 1
    GL343225.1(1400819-1424122)
    GL343225.1(1432913-1489358)
    African clawed frog
    (Xenopus laevis)
    Amphibia CF284530.12   -- 80.29(n)    CF284530.1 
    zebrafish
    (Danio rerio)
    Actinopterygii FAM120A6
    family with sequence similarity 120A
    71(a)
    1 ↔ 1
    11(28583419-28615329)


    ENSEMBL Gene Tree for FAM120A (if available)
    TreeFam Gene Tree for FAM120A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAM120A gene
    FAM120C2  C9orf1292  FAM120B2  
    2 SIMAP similar genes for FAM120A using alignment to 2 protein entries:     F120A_HUMAN (see all proteins):
    C9orf129    FAM120C

    FAM120A for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FAM120A
    PGOHUM00000238012


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2124 SNPs in FAM120A are shown (see all 2124)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1465134901,2
    --65889444(+) AGCTGA/GGACTA 1 -- us2k10--------
    rs794540031,2
    C--65889466(+) CACCAG/CGCTCG 1 -- us2k11Minor allele frequency- C:0.50WA 2
    rs1445871771,2
    --65889471(+) CGCTCC/GGCTAA 1 -- us2k10--------
    rs117917191,2
    H--65889507(+) gttttA/Cccatg 1 -- us2k1 tfbs30--------
    rs1482216841,2
    C--65889511(+) TACCAC/TGTTGG 1 -- us2k10--------
    rs1816316111,2
    C--65889569(+) TCCCAA/GCGTGC 1 -- us2k10--------
    rs78629981,2
    C--65889606(+) cccggC/GcGCAC 1 -- us2k14Minor allele frequency- G:0.27WA NA EA 242
    rs78631151,2
    C,F--65889636(+) AAAAGC/TAAGAG 1 -- us2k1 tfbs31Minor allele frequency- T:0.05WA 118
    rs61510791,2
    C--65941373(+) cacat-/ACA   
       CACAC
    acaca
    1 -- int10--------
    rs1896856091,2
    --96218014(+) ATCTCG/TGCTCA 1 -- int10--------

    HapMap Linkage Disequilibrium report for FAM120A (96214004 - 96328397 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FAM120A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2662964CNV Deletion23128226
    nsv824984CNV Gain20364138


    Human Gene Mutation Database (HGMD): FAM120A
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612265    OMIM disorders: --

    3 diseases for FAM120A:    About MalaCards
    myiasis    achondrogenesis    gastric cancer

    2 diseases from the University of Copenhagen DISEASES database for FAM120A:
    Myiasis     Achondrogenesis

    FAM120A for disorders           About GeneDecksing

    Genetic Association Database (GAD): FAM120A
    Human Genome Epidemiology (HuGE) Navigator: FAM120A (1 document)

    Export disorders for FAM120A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAM120A gene, integrated from 9 sources (see all 31):
    (articles sorted by number of sources associating them with FAM120A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. (PubMed id 14585507)1, 2, 3 Holden S. and Raymond F.L. (2003)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (2010)
    3. A novel RNA-binding protein, Ossa/C9orf10, regulates activity of Src kinases to protect cells from oxidative stress-induced apoptosis. (PubMed id 19015244)1, 2 Tanaka M.... Sakai R. (2009)
    4. DNA sequence and analysis of human chromosome 9. (PubMed id 15164053)1, 2 Humphray S.J.... Dunham I. (2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 8724849)1, 2 Nagase T.... Nomura N. (1996)
    7. Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
    8. Functional proteomics establishes the interaction of S IRT7 with chromatin remodeling complexes and expands its role in regulation of R NA polymerase I transcription. (PubMed id 22586326)1 Tsai Y.C....Cristea I.M. (2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23196 HGNC: 13247 AceView: C9orf10 Ensembl:ENSG00000048828 euGenes: HUgn23196
    ECgene: FAM120A H-InvDB: FAM120A

    (According to HUGE)
    About This Section
    HUGE: KIAA0183

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FAM120A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FAM120A gene:
    Search GeneIP for patents involving FAM120A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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