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FAM117B Gene

protein-coding   GIFtS: 46
GCID: GC02P203499

Family With Sequence Similarity 117, Member B

(Previous names: amyotrophic lateral sclerosis 2 (juvenile) chromosome region,...)
(Previous symbol: ALS2CR13)
  See FAM117B-related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 117, Member B1 2
ALS2CR131 2 3
Amyotrophic Lateral Sclerosis 2 (Juvenile) Chromosome Region, Candidate 131 2
Amyotrophic Lateral Sclerosis 2 Chromosomal Region Candidate Gene 13
Protein2 3
Protein FAM117B2

External Ids:    HGNC: 144401   Entrez Gene: 1508642   Ensembl: ENSG000001384397   UniProtKB: Q6P1L53   

Export aliases for FAM117B gene to outside databases

Previous GC identifers: GC02P203209 GC02P195346


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM117B Gene:
FAM117B (family with sequence similarity 117, member B) is a protein-coding gene. Diseases associated with FAM117B include lateral sclerosis, and amyotrophic lateral sclerosis. An important paralog of this gene is GLCCI1.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM117B gene promoter:
         MAZR   SRF (504 AA)   NF-AT   NF-AT4   NF-AT2   FOXJ2 (long isoform)   NF-AT3   FOXJ2   En-1   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM117B promoter sequence
   Search Chromatin IP Primers for FAM117B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM117B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q33.2   Ensembl cytogenetic band:  2q33.2   HGNC cytogenetic band: 2q33

FAM117B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM117B gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P203499:  view genomic region     (about GC identifiers)

Start:
203,499,901 bp from pter      End:
203,634,480 bp from pter
Size:
134,580 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: F117B_HUMAN, Q6P1L5 (See protein sequence)
Recommended Name: Protein FAM117B  
Size: 589 amino acids; 61968 Da
Miscellaneous: ALS2CR13 is mapped in the genomic region covering the complete candidate region for Amyotrophic
lateral sclerosis 2 (ALS2)
Sequence caution: Sequence=AAI06907.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAI06908.1; Type=Erroneous initiation; Note=Translation N-terminally extended; Sequence=AAX76518.1;
Type=Erroneous gene model prediction; Sequence=BAB69023.1; Type=Frameshift; Positions=150; Sequence=BAB69023.1;
Type=Miscellaneous discrepancy; Note=Contaminating sequence. Sequence of unknown origin in the N-terminal part;
Sequence=BAC04700.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: Q53QZ5 Q585T9 Q8N8W1 Q96Q34
Alternative splicing: 2 isoforms:  Q6P1L5-1   Q6P1L5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM117B: NX_Q6P1L5

Explore proteomics data for FAM117B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM117B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_775782.2  
    ENSEMBL proteins: 
     ENSP00000376071   ENSP00000306299  

    FAM117B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for FAM117B

     
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    Novus Biologicals FAM117B Antibody
    Abcam antibodies for FAM117B
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    LSBio Antibodies in human, mouse, rat for FAM117B

    FAM117B Assay Products:

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    Cloud-Clone Corp. ELISAs for FAM117B
    Cloud-Clone Corp. CLIAs for FAM117B
    Search eBioscience for ELISAs for FAM117B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    2 InterPro protein domains:
     IPR026642 Glcci1/FAM117
     IPR026641 FAM117B

    Graphical View of Domain Structure for InterPro Entry Q6P1L5

    ProtoNet protein and cluster: Q6P1L5


    Find genes that share domains with FAM117B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         1 GenomeRNAi human phenotype for FAM117B:
     Increased G1 DNA content 

         6 MGI mutant phenotypes (inferred from 1 allele(MGI details for Fam117b):
     behavior/neurological  growth/size/body  hematopoietic system  homeostasis/metabolism  skeleton 
     vision/eye 

    Find genes that share phenotypes with FAM117B           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM117B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM117B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM117B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM117B

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM117B:
    hsa-mir-122-5p (MIRT003728), hsa-mir-186-5p (MIRT045030)

    Block miRNA regulation of human, mouse, rat FAM117B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM117B (see all 112):
    hsa-miR-411* hsa-miR-124* hsa-miR-26a-2* hsa-miR-520f hsa-miR-188-5p hsa-miR-106a hsa-miR-578 hsa-miR-138-2*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM117B

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    GenScript: all cDNA clones in your preferred vector: FAM117B (NM_173511)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM117B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM117B

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    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM117B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytosol2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM117B
    Interactions:

        Search GeneGlobe Interaction Network for FAM117B

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    3 Interacting proteins for FAM117B (Q6P1L52, 3 ENSP000003062994) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SFNP319472, 3MINT-3976465 I2D: score=1 
    MYCP011063, ENSP000003672074I2D: score=1 STRING: ENSP00000367207
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM117B (F117B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM117B gene: 
    NM_173511.3  

    Unigene Cluster for FAM117B:

    Family with sequence similarity 117, member B
    Hs.471130  [show with all ESTs]
    Unigene Representative Sequence: NM_173511
    3 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000392238 ENST00000481658 ENST00000303116(uc010zhw.2 uc010zhx.2)

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM117B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM117B (see all 112):
    hsa-miR-411* hsa-miR-124* hsa-miR-26a-2* hsa-miR-520f hsa-miR-188-5p hsa-miR-106a hsa-miR-578 hsa-miR-138-2*
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM117B
    Predesigned siRNA for gene silencing in human, mouse, rat FAM117B
    Clone
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    OriGene clones in human, mouse for FAM117B (see all 10)
    OriGene ORF clones in mouse, rat for FAM117B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM117B (NM_173511)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM117B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM117B
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM117B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM117B
      QuantiTect SYBR Green Assays in human, mouse, rat FAM117B
      QuantiFast Probe-based Assays in human, mouse, rat FAM117B

    Additional mRNA sequence: 

    AB053315.1 AK025007.1 AK096090.1 BC021689.1 BC065010.1 BC106906.2 BC106907.2 BX537704.1 

    6 DOTS entries:

    DT.97821726  DT.86843185  DT.100706364  DT.65285005  DT.100647993  DT.86836329 

    Selected AceView cDNA sequences (see all 65):

    AA045152 BF432045 BF513436 BM556486 AK025007 AA383157 AI523857 AA905811 
    BU166643 CR614335 AL700301 BG249761 BX537704 AA488132 AA303223 BF029264 
    AA332497 AK096090 BX430915 BG613474 AI082200 BP428673 BC021689 BC065010 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM117B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAAGTCCTTT
    FAM117B Expression
    About this image

    FAM117B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM117B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.471130
        Custom PCR Arrays for FAM117B
    Primer
    Products:
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM117B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM117B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM117B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FAM117B gene from Selected species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam117b1 , 5 family with sequence similarity 117, member B1, 5 86.81(n)1
    90.89(a)1
      1 (30.44 cM)5
    727501  NM_001037725.31  NP_001032814.11 
     599130065 
    chicken
    (Gallus gallus)
    Aves FAM117B1 family with sequence similarity 117, member B 81.44(n)
    87.86(a)
      424088  XM_004942630.1  XP_004942687.1 
    lizard
    (Anolis carolinensis)
    Reptilia FAM117B6
    family with sequence similarity 117, member B
    57(a)
    1 ↔ 1
    GL343208.1(3593654-3626337)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.133462 Transcribed sequence with weak similarity to protein more 80.93(n)    AL776748.2 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-56k23.21 si:dkey-56k23.2 60.75(n)
    59.96(a)
      100003476  NM_001128362.1  NP_001121834.1 


    ENSEMBL Gene Tree for FAM117B (if available)
    TreeFam Gene Tree for FAM117B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM117B gene
    GLCCI12  FAM117A2  
    2 SIMAP similar genes for FAM117B using alignment to 1 protein entry:     F117B_HUMAN:
    DKFZp686H01244    GLCCI1

    Find genes that share paralogs with FAM117B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM117B (see all 2341)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1399793551,2
    --195344945(+) CCTTGA/GTTAAT 1 -- us2k10--------
    rs75816011,2
    C,F,H--195344948(+) TGGttA/Cataat 1 -- us2k1 tfbs321Minor allele frequency- C:0.14NS EA NA WA 2646
    rs1918978321,2
    --195344954(+) ATAATC/TATAAC 1 -- us2k10--------
    rs1454063661,2
    --195344989(+) TTTAAA/CTGCAT 1 -- us2k10--------
    rs1476778621,2
    --195345020(+) CTAGTA/GATCCA 1 -- us2k10--------
    rs1819266491,2
    C--203498019(+) CCTCCC/TGGGTT 1 -- us2k10--------
    rs1875622471,2
    --203498158(+) CCGACC/TTCAGG 1 -- us2k10--------
    rs1409335131,2
    --203498348(+) AAACCA/GCCTCT 1 -- us2k10--------
    rs1131226561,2
    F--203498350(+) ACCGCT/CTCTTT 1 -- us2k11Minor allele frequency- C:0.00CSA 1
    rs730527731,2
    C,F--203498367(+) AACAGA/GAAAAT 1 -- us2k12Minor allele frequency- G:0.05WA 120

    HapMap Linkage Disequilibrium report for FAM117B (203499901 - 203634480 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for FAM117B:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2579724CNV Deletion19546169
    nsv507064CNV Insertion20534489
    nsv3114CNV Insertion18451855
    nsv470510CNV Gain18288195
    nsv460019CNV Gain19166990
    nsv460020CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM117B
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM117B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    2 diseases for FAM117B:    
    About MalaCards
    lateral sclerosis    amyotrophic lateral sclerosis


    Find genes that share disorders with FAM117B           About GenesLikeMe

    Genetic Association Database (GAD): FAM117B

    Export disorders for FAM117B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM117B gene, integrated from 10 sources (see all 18):
    (articles sorted by number of sources associating them with FAM117B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A gene encoding a putative GTPase regulator is mutated in familial amyotrophic lateral sclerosis 2. (PubMed id 11586298)1, 2, 3 Hadano S....Ikeda J.-E. (Nat. Genet. 2001)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Proteomic analysis of ubiquitin ligase KEAP1 reveals associated proteins that inhibit NRF2 ubiquitination. (PubMed id 23382044)1 Hast B.E....Major M.B. (Cancer Res. 2013)
    4. The protein interaction landscape of the human CMGC kinase group. (PubMed id 23602568)1 Varjosalo M....Gstaiger M. (Cell Rep 2013)
    5. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (Sci. Signal. 2011)
    6. Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis. (PubMed id 20068231)2 Olsen J.V....Mann M. (Sci. Signal. 2010)
    7. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (Sci. Signal. 2009)
    9. Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (EMBO J. 2009)
    10. Combining protein-based IMAC, peptide-based IMAC, and MudPIT for efficient phosphoproteomic analysis. (PubMed id 18220336)2 Cantin G.T....Yates J.R. III (J. Proteome Res. 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 150864 HGNC: 14440 AceView: ALS2CR13 Ensembl:ENSG00000138439 euGenes: HUgn150864
    ECgene: FAM117B H-InvDB: FAM117B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM117B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM117B gene:
    Search GeneIP for patents involving FAM117B

    GeneCards and IP:
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    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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     OriGene Antibodies for FAM117B   OriGene RNAi products in human, mouse, rat for FAM117B  
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     Block miRNA regulation of human, mouse, rat FAM117B using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FAM117B
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     Custom PCR Arrays for FAM117B Search Chromatin IP Primers for FAM117B
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     Search Addgene for plasmids for FAM117B
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      eBioscience FlowRNA Probe Sets
           
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