Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM117A Gene

Aliases for FAM117A Gene

  • Family With Sequence Similarity 117, Member A 2 3
  • C/EBP Induced Protein 2
  • C/EBP-Induced Protein 4

External Ids for FAM117A Gene

Previous GeneCards Identifiers for FAM117A Gene

  • GC17M045143
  • GC17M047787
  • GC17M043152

Summaries for FAM117A Gene

GeneCards Summary for FAM117A Gene

FAM117A (Family With Sequence Similarity 117, Member A) is a Protein Coding gene. An important paralog of this gene is GLCCI1.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM117A Gene

Genomics for FAM117A Gene

Regulatory Elements for FAM117A Gene

Genomic Location for FAM117A Gene

Start:
49,710,325 bp from pter
End:
49,789,180 bp from pter
Size:
78,856 bases
Orientation:
Minus strand

Genomic View for FAM117A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM117A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM117A Gene

Proteins for FAM117A Gene

  • Protein details for FAM117A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9C073-F117A_HUMAN
    Recommended name:
    Protein FAM117A
    Protein Accession:
    Q9C073
    Secondary Accessions:
    • B7Z7Q3

    Protein attributes for FAM117A Gene

    Size:
    453 amino acids
    Molecular mass:
    48319 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for FAM117A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM117A Gene

Proteomics data for FAM117A Gene at MOPED

Post-translational modifications for FAM117A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM117A Gene

No data available for DME Specific Peptides for FAM117A Gene

Domains for FAM117A Gene

Protein Domains for FAM117A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM117A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9C073

UniProtKB/Swiss-Prot:

F117A_HUMAN :
  • Q9C073
Family:
  • Belongs to the FAM117 family.
genes like me logo Genes that share domains with FAM117A: view

No data available for Gene Families for FAM117A Gene

Function for FAM117A Gene

miRNA for FAM117A Gene

miRTarBase miRNAs that target FAM117A

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM117A Gene

Localization for FAM117A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM117A Gene COMPARTMENTS Subcellular localization image for FAM117A gene
Compartment Confidence
cytosol 2
mitochondrion 2
nucleus 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM117A Gene

Pathways for FAM117A Gene

SuperPathways for FAM117A Gene

No Data Available

Interacting Proteins for FAM117A Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000240364%0d%0a9606.ENSP00000312789%0d%0a9606.ENSP00000381932%0d%0a
Selected Interacting proteins: ENSP00000240364 Q9C073-F117A_HUMAN for FAM117A Gene via STRING I2D

Gene Ontology (GO) - Biological Process for FAM117A Gene

None

No data available for Pathways by source for FAM117A Gene

Transcripts for FAM117A Gene

mRNA/cDNA for FAM117A Gene

Unigene Clusters for FAM117A Gene

Family with sequence similarity 117, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM117A Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b ^ 9 ^ 10 ^ 11a · 11b ^ 12a · 12b
SP1: - - - -
SP2: -
SP3: - -
SP4:
SP5: -
SP6: - - -

Relevant External Links for FAM117A Gene

GeneLoc Exon Structure for
FAM117A
ECgene alternative splicing isoforms for
FAM117A

Expression for FAM117A Gene

mRNA expression in normal human tissues for FAM117A Gene

mRNA differential expression in normal tissues according to GTEx for FAM117A Gene

This gene is overexpressed in Whole Blood (6.0).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM117A Gene

SOURCE GeneReport for Unigene cluster for FAM117A Gene Hs.514308

genes like me logo Genes that share expressions with FAM117A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for FAM117A Gene

Orthologs for FAM117A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM117A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM117A 35
  • 99.31 (n)
  • 99.23 (a)
FAM117A 36
  • 95 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM117A 35
  • 91.53 (n)
  • 92.97 (a)
FAM117A 36
  • 93 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM117A 35
  • 90.61 (n)
  • 92.96 (a)
FAM117A 36
  • 93 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam117a 35
  • 86.64 (n)
  • 86.32 (a)
Fam117a 16
Fam117a 36
  • 88 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM117A 36
  • 40 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam117a 35
  • 85.62 (n)
  • 86.58 (a)
chicken
(Gallus gallus)
Aves FAM117A 36
  • 57 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM117A 36
  • 53 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii cdh1 35
FAM117A (1 of 2) 36
  • 41 (a)
OneToMany
FAM117A (2 of 2) 36
  • 33 (a)
OneToMany
LOC101887152 35
  • 64.2 (n)
  • 60.49 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.5186 36
  • 23 (a)
OneToMany
Species with no ortholog for FAM117A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM117A Gene

ENSEMBL:
Gene Tree for FAM117A (if available)
TreeFam:
Gene Tree for FAM117A (if available)

Paralogs for FAM117A Gene

Paralogs for FAM117A Gene

Selected SIMAP similar genes for FAM117A Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with FAM117A: view

Variants for FAM117A Gene

Sequence variations from dbSNP and Humsavar for FAM117A Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs878829 -- 49,749,005(+) TTCAC(C/T)GACTA intron-variant
rs1443109 -- 49,741,689(+) AACAG(A/G)AATTC intron-variant
rs1822349 -- 49,742,657(+) TATCT(C/T)TAAAA intron-variant
rs1947001 -- 49,742,900(+) ACCAT(A/G)ATTGA intron-variant
rs2012322 -- 49,729,411(+) TGGTA(C/T)GACTA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM117A Gene

Variant ID Type Subtype PubMed ID
nsv525469 CNV Gain 19592680
esv23674 CNV Loss 19812545
esv2660684 CNV Deletion 23128226
nsv111821 CNV Loss 16902084

Relevant External Links for FAM117A Gene

HapMap Linkage Disequilibrium report
FAM117A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM117A Gene

Disorders for FAM117A Gene

No disorders were found for FAM117A Gene.

No data available for UniProtKB/Swiss-Prot for FAM117A Gene

Publications for FAM117A Gene

  1. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. The protein interaction landscape of the human CMGC kinase group. (PMID: 23602568) Varjosalo M. … Gstaiger M. (Cell Rep 2013) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody M.C. … Nusbaum C. (Nature 2006) 4

Products for FAM117A Gene

Sources for FAM117A Gene

Back to Top

Content