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FAM115A Gene

protein-coding   GIFtS: 42
GCID: GC07M143548

Family With Sequence Similarity 115, Member A

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 115, Member A1 2
Protein FAM115A2
KIAA07383

External Ids:    HGNC: 222011   Entrez Gene: 97472   Ensembl: ENSG000001984207   UniProtKB: Q9Y4C23   

Export aliases for FAM115A gene to outside databases

Previous GC identifers: GC07M143185 GC07M137749


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM115A Gene:
FAM115A (family with sequence similarity 115, member A) is a protein-coding gene. Diseases associated with FAM115A include ataxia. An important paralog of this gene is FAM115C.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the FAM115A gene promoter:
         HOXA3   Evi-1   NF-AT   NF-AT4   NF-AT2   FOXO4   Chx10   NF-AT3   NF-AT1   RSRFC4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 8): FAM115A promoter sequence
   Search Chromatin IP Primers for FAM115A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM115A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q35   Ensembl cytogenetic band:  7q35   HGNC cytogenetic band: 7q35

FAM115A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM115A gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07M143548:  view genomic region     (about GC identifiers)

Start:
143,548,461 bp from pter      End:
143,599,291 bp from pter
Size:
50,831 bases      Orientation:
minus strand

1 alternative location:
Chr7-,CRA_TCAG 142,886,627-142,937,442     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: F115A_HUMAN, Q9Y4C2 (See protein sequence)
Recommended Name: Protein FAM115A  
Size: 921 amino acids; 102126 Da
Sequence caution: Sequence=BAA34458.2; Type=Erroneous initiation;
Secondary accessions: A8K6E0 Q75KM8 Q75KM9 Q7L665 Q9BW63
Alternative splicing: 2 isoforms:  Q9Y4C2-1   Q9Y4C2-2   

Explore the universe of human proteins at neXtProt for FAM115A: NX_Q9Y4C2

Explore proteomics data for FAM115A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys274, Lys281, Lys434, Lys439, Lys632, Lys750, Lys817, Lys865, Lys912
  • Modification sites at PhosphoSitePlus

  • See FAM115A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001193867.1  NP_001193870.1  NP_055534.1  

    ENSEMBL proteins: 
     ENSP00000419235   ENSP00000348220   ENSP00000420607   ENSP00000417600   ENSP00000419622  
     ENSP00000418432  

    FAM115A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FAM115A
    OriGene Protein Over-expression Lysate for FAM115A
    OriGene MassSpec for FAM115A
    OriGene Custom Protein Services for FAM115A
    GenScript Custom Purified and Recombinant Proteins Services for FAM115A
    Novus Biologicals FAM115A Protein
    Novus Biologicals FAM115A Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAM115A

    FAM115A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for FAM115A
    Search for Antibodies for FAM115A at Abcam
    Cloud-Clone Corp. Antibodies for FAM115A
    Search ThermoFisher Antibodies for FAM115A
    LSBio Antibodies in human, mouse, rat for FAM115A

    FAM115A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FAM115A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FAM115A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FAM115A
    Cloud-Clone Corp. CLIAs for FAM115A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    ProtoNet protein and cluster: Q9Y4C2

    UniProtKB/Swiss-Prot: F115A_HUMAN, Q9Y4C2
    Similarity: Belongs to the FAM115 family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM115A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM115A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM115A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM115A

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM115A:
    hsa-mir-877-3p (MIRT037174), hsa-mir-378a-5p (MIRT043979)

    Block miRNA regulation of human, mouse, rat FAM115A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM115A (see all 39):
    hsa-miR-548j hsa-miR-4328 hsa-miR-624 hsa-miR-219-5p hsa-miR-578 hsa-miR-138-2* hsa-miR-764 hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmidFAM115A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAM115A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM115A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FAM115A

    Clone
    Products:
         
    OriGene clones in human, mouse for FAM115A (see all 5)
    OriGene ORF clones in mouse, rat for FAM115A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM115A (NM_014719)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM115A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM115A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FAM115A
    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM115A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM115A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol2
    nucleus2
    plasma membrane2
    peroxisome1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM115A
    Interactions:

        Search GeneGlobe Interaction Network for FAM115A

    STRING Interaction Network Preview (showing 5 interactants - click image to see 7)

    Selected Interacting proteins for FAM115A (Q9Y4C23 ENSP000004192354) via UniProtKB, MINT, STRING, and/or I2D (see all 10)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    COILP384323, ENSP000002403164I2D: score=3 STRING: ENSP00000240316
    EFEMP2O959673, ENSP000003099534I2D: score=3 STRING: ENSP00000309953
    USP13Q929953, ENSP000002639664I2D: score=2 STRING: ENSP00000263966
    TOLLIPQ9H0E23, ENSP000003147334I2D: score=1 STRING: ENSP00000314733
    UBCP0CG483, ENSP000003448184I2D: score=1 STRING: ENSP00000344818
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM115A (F115A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FAM115A gene (3 alternative transcripts): 
    NM_001206938.1  NM_001206941.1  NM_014719.2  

    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000479870(uc011ktu.2 uc003wdo.2 uc003wdp.2) ENST00000355951
    ENST00000392900 ENST00000460532 ENST00000491908 ENST00000478172 ENST00000485416

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM115A using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM115A (see all 39):
    hsa-miR-548j hsa-miR-4328 hsa-miR-624 hsa-miR-219-5p hsa-miR-578 hsa-miR-138-2* hsa-miR-764 hsa-miR-374c
    SwitchGear 3'UTR luciferase reporter plasmidFAM115A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM115A
    Predesigned siRNA for gene silencing in human, mouse, rat FAM115A
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM115A (see all 5)
    OriGene ORF clones in mouse, rat for FAM115A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM115A (NM_014719)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM115A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM115A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FAM115A
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM115A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM115A
      QuantiTect SYBR Green Assays in human, mouse, rat FAM115A
      QuantiFast Probe-based Assays in human, mouse, rat FAM115A

    Selected AceView cDNA sequences (see all 384):

    BU677827 Z42047 AA077622 BF439838 AA256990 AI435061 AF119896 AA251748 
    BX282090 T16469 AW160352 CF125361 AA504900 BQ881206 AA625240 AA429006 
    CA314129 BP348619 AI696613 AB018281 BU752047 BU527109 AA593737 BF110496 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM115A (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e ^ 2 ^ 3a · 3b ^ 4 ^ 5a · 5b · 5c · 5d · 5e · 5f ^ 6 ^ 7 ^ 8 ^ 9 ^ 10a · 10b ^ 11a · 11b ^ 12a · 12b
    SP1:                                -     -     -     -                                                                                   -               
    SP2:                          -     -     -     -     -                                                                                                   
    SP3:                                      -     -                                                                                                         
    SP4:                                                                                                                                                      
    SP5:                                                                                                                                                      


    ECgene alternative splicing isoforms for FAM115A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM115A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TATTACTTTG
    FAM115A Expression
    About this image


    FAM115A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 2) fully expand
     
     Adipose (Muscoskeletal System)
             Visceral White Adipose
     
     Eye (Sensory Organs)
             Retina
    FAM115A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM115A Protein Expression
        Custom PCR Arrays for FAM115A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FAM115A
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM115A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM115A
    QuantiTect SYBR Green Assays in human, mouse, rat FAM115A
    QuantiFast Probe-based Assays in human, mouse, rat FAM115A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM115A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FAM115A gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam115a1 , 5 family with sequence similarity 115, member A1, 5 86.51(n)1
    90.53(a)1
      6 (20.84 cM)5
    775741  NM_029930.21  NP_084206.11 
     426680025 
    lizard
    (Anolis carolinensis)
    Reptilia --
    --
    Uncharacterized protein
    44(a)
    42(a)
    many ↔ many
    many ↔ many
    GL343236.1(1123926-1138603)
    5(980783-992491)
    zebrafish
    (Danio rerio)
    Actinopterygii si:ch211-210b2.46
    zgc:1621936
    (see all 4)
    zgc:162193
    (see all 4)
    38(a)
    38(a)
    (see all 4)
    many ↔ many
    many ↔ many
    (see all 4)
    15(646748-650496) ENSDARG00000095212
    15(13984891-13991838) ENSDARG00000089286


    ENSEMBL Gene Tree for FAM115A (if available)
    TreeFam Gene Tree for FAM115A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM115A gene
    FAM115C2  
    1 SIMAP similar gene for FAM115A using alignment to 5 protein entries:     F115A_HUMAN (see all proteins):
    FAM115C

    FAM115A for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FAM115A
    PGOHUM00000233617


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM115A (see all 617)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1478707751,2
    --143548409(+) GGACCC/TTGAAA 3 -- int10--------
    rs1489344791,2
    --143548443(+) GTTGCA/GTCTTA 3 -- int10--------
    rs1931889961,2
    --143549058(+) GATCTA/GAACAT 3 -- ut310--------
    rs1833407281,2
    --143549076(+) TAATAA/CATGAT 3 -- ut310--------
    rs1481686421,2
    --143549211(+) GCCTCG/TTCTTA 3 -- ut310--------
    rs2016596281,2
    C--143549350(+) CTTCAA/GTGATA 3 -- ut310--------
    rs1410177921,2
    --143549657(+) TGACAC/GTCTGC 3 -- ut310--------
    rs1908009501,2
    C--143550003(+) CCTAAC/GATTAC 3 -- ut310--------
    rs2011051891,2
    C--143550398(+) GGTCTC/TGAACT 3 -- ut310--------
    rs2001668621,2
    C--143554451(+) GGGAAA/GAGAAA 3 -- int10--------

    HapMap Linkage Disequilibrium report for FAM115A (143548461 - 143599291 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for FAM115A (see all 25):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2422489CNV Duplication17116639
    nsv889338CNV Loss21882294
    dgv7516n71CNV Loss21882294
    dgv7518n71CNV Loss21882294
    dgv7508n71CNV Loss21882294
    dgv7517n71CNV Gain21882294
    nsv522225CNV Gain19592680
    esv2752147CNV Gain17911159
    dgv7520n71CNV Gain21882294
    dgv842n27CNV Gain19166990

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FAM115A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM115A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for FAM115A:    
    About MalaCards
    ataxia


    FAM115A for disorders           About GeneDecksing


    Export disorders for FAM115A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM115A gene, integrated from 10 sources (see all 21):
    (articles sorted by number of sources associating them with FAM115A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2, 3 Nagase T.... Ohara O. (DNA Res. 1998)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    3. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    4. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    5. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    6. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S.... Dorf M.E. (Immunity 2011)
    7. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    8. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    9. Systematic and quantitative assessment of the ubiquitin-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (Mol. Cell 2011)
    10. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 9747 HGNC: 22201 AceView: KIAA0738 Ensembl:ENSG00000198420 euGenes: HUgn9747
    ECgene: FAM115A H-InvDB: FAM115A

    (According to HUGE)
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    HUGE: KIAA0738

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM115A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for FAM115A gene:
    Search GeneIP for patents involving FAM115A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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