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Aliases for FAM110D Gene

Aliases for FAM110D Gene

  • Family With Sequence Similarity 110 Member D 2 3 5
  • GRRP1 3 4
  • Family With Sequence Similarity 110, Member D 2
  • Glycine/Arginine Rich Protein 1 2
  • Glycine/Arginine-Rich Protein 1 3
  • Protein FAM110D 3

External Ids for FAM110D Gene

Previous HGNC Symbols for FAM110D Gene

  • GRRP1

Previous GeneCards Identifiers for FAM110D Gene

  • GC01P026486

Summaries for FAM110D Gene

GeneCards Summary for FAM110D Gene

FAM110D (Family With Sequence Similarity 110 Member D) is a Protein Coding gene. An important paralog of this gene is FAM110A.

Additional gene information for FAM110D Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM110D Gene

Genomics for FAM110D Gene

Regulatory Elements for FAM110D Gene

Enhancers for FAM110D Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH01H026274 2 FANTOM5 Ensembl ENCODE dbSUPER 17.2 +124.9 124886 19 HNRNPUL1 HDGF PKNOX1 ARNT ARID4B SIN3A ZNF2 YY1 ZNF766 ZNF143 HMGN2 ARID1A LOC101928324 CD52 UBXN11 CEP85 GPN2 LIN28A NPM1P39 TRIM63
GH01H026121 2 FANTOM5 Ensembl ENCODE dbSUPER 12.6 -33.8 -33776 7 HDGF PKNOX1 ARNT SIN3A FEZF1 ZNF2 ZNF766 ZNF302 FOS REST ARID1A HMGN2 LOC101928324 ENSG00000261349 TRIM63 SYF2 GPN2 ZNF593 LOC101928728 RPL17P9
GH01H026034 1.6 Ensembl ENCODE dbSUPER 10.8 -122.0 -122001 4 PKNOX1 ZFP64 ARID4B FEZF1 DMAP1 ZNF2 ZNF143 FOS SP3 NFYC TRIM63 PAFAH2 ENSG00000252190 ENSG00000252691 FAM110D ENSG00000236782 ZNF593 LIN28A CNKSR1 ENSG00000225643
GH01H025988 1.7 FANTOM5 Ensembl ENCODE dbSUPER 9.9 -167.3 -167250 7 HDAC1 PKNOX1 TCF12 ZNF121 ZBTB11 ZEB2 PPARG ZNF592 TFDP1 ZNF589 PAFAH2 RNU6-110P STMN1 EXTL1 SLC30A2 TRIM63 FAM110D PIR35611 GC01M025975
GH01H026408 1.6 Ensembl ENCODE dbSUPER 9.8 +255.7 255743 12 PKNOX1 MLX ARNT ZFP64 ARID4B SIN3A DMAP1 SLC30A9 ZNF766 CBX5 ZNF683 CD52 UBXN11 HMGN2 ZNF593 ENSG00000236782 FAM110D RPS6KA1 SLC30A2 EXTL1
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM110D on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM110D Gene

26,159,008 bp from pter
26,163,962 bp from pter
4,955 bases
Plus strand

Genomic View for FAM110D Gene

Genes around FAM110D on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM110D Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM110D Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM110D Gene

Proteins for FAM110D Gene

  • Protein details for FAM110D Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM110D
    Protein Accession:
    Secondary Accessions:
    • A8K3V0
    • Q9H7Z4

    Protein attributes for FAM110D Gene

    271 amino acids
    Molecular mass:
    28710 Da
    Quaternary structure:
    No Data Available
    • Sequence=BAB14829.1; Type=Frameshift; Positions=90; Evidence={ECO:0000305};

neXtProt entry for FAM110D Gene

Post-translational modifications for FAM110D Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM110D Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM110D Gene

Domains & Families for FAM110D Gene

Gene Families for FAM110D Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM110D Gene


Suggested Antigen Peptide Sequences for FAM110D Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the FAM110 family.
  • Belongs to the FAM110 family.
genes like me logo Genes that share domains with FAM110D: view

Function for FAM110D Gene

Phenotypes From GWAS Catalog for FAM110D Gene

genes like me logo Genes that share phenotypes with FAM110D: view

Animal Model Products

CRISPR Products

miRNA for FAM110D Gene

miRTarBase miRNAs that target FAM110D

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for FAM110D
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM110D Gene

Localization for FAM110D Gene

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for FAM110D gene
Compartment Confidence
nucleus 3
extracellular 1
mitochondrion 1
cytosol 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM110D Gene

Pathways & Interactions for FAM110D Gene

SuperPathways for FAM110D Gene

No Data Available

Interacting Proteins for FAM110D Gene

Gene Ontology (GO) - Biological Process for FAM110D Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM110D Gene

Drugs & Compounds for FAM110D Gene

No Compound Related Data Available

Transcripts for FAM110D Gene

mRNA/cDNA for FAM110D Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(20) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM110D Gene

Family with sequence similarity 110, member D:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for FAM110D
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for FAM110D Gene

No ASD Table

Relevant External Links for FAM110D Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM110D Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM110D Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM110D Gene

This gene is overexpressed in Adipose - Visceral (Omentum) (x4.5).

Protein differential expression in normal tissues from HIPED for FAM110D Gene

This gene is overexpressed in Serum (54.5) and Plasma (14.5).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for FAM110D Gene

Protein tissue co-expression partners for FAM110D Gene

- Elite partner

NURSA nuclear receptor signaling pathways regulating expression of FAM110D Gene:


SOURCE GeneReport for Unigene cluster for FAM110D Gene:

genes like me logo Genes that share expression patterns with FAM110D: view

Primer Products

No data available for mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM110D Gene

Orthologs for FAM110D Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM110D Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia FAM110D 33 34
  • 99.38 (n)
(Canis familiaris)
Mammalia FAM110D 33 34
  • 89.91 (n)
(Bos Taurus)
Mammalia FAM110D 33 34
  • 89.14 (n)
(Mus musculus)
Mammalia Grrp1 33 16 34
  • 86.47 (n)
(Rattus norvegicus)
Mammalia Fam110d 33
  • 85.12 (n)
(Gallus gallus)
Aves FAM110D 33 34
  • 59.51 (n)
(Anolis carolinensis)
Reptilia FAM110D 34
  • 45 (a)
(Danio rerio)
Actinopterygii si:ch211-107n13.1 33
  • 53.86 (n)
FAM110D 34
  • 22 (a)
Species where no ortholog for FAM110D was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM110D Gene

Gene Tree for FAM110D (if available)
Gene Tree for FAM110D (if available)

Paralogs for FAM110D Gene

Paralogs for FAM110D Gene

genes like me logo Genes that share paralogs with FAM110D: view

Variants for FAM110D Gene

Sequence variations from dbSNP and Humsavar for FAM110D Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs1000411501 -- 26,161,946(+) GCGTG(A/G)ACAGC reference, missense
rs1001074106 -- 26,158,845(+) CTAAC(A/C/T)GGGCT upstream-variant-2KB
rs1001549306 -- 26,162,286(+) CGAAG(G/T)GGGAG utr-variant-3-prime
rs1001819806 -- 26,160,550(+) GCCCC(C/T)CTCCT intron-variant
rs1002422694 -- 26,159,259(+) GAGAC(C/G)ACAAG intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM110D Gene

Variant ID Type Subtype PubMed ID
nsv1002191 CNV gain 25217958

Variation tolerance for FAM110D Gene

Gene Damage Index Score: 6.81; 79.15% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM110D Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM110D Gene

Disorders for FAM110D Gene

Relevant External Links for FAM110D

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM110D Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM110D Gene

Publications for FAM110D Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 60
  4. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 4 60
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 4 60

Products for FAM110D Gene

Sources for FAM110D Gene

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