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Aliases for FAM110A Gene

Aliases for FAM110A Gene

  • Family With Sequence Similarity 110, Member A 2 3
  • C20orf55 3 4 6
  • F10 3 4
  • Chromosome 20 Open Reading Frame 55 2
  • Protein FAM110A 3
  • BA371L19.3 3

External Ids for FAM110A Gene

Previous HGNC Symbols for FAM110A Gene

  • C20orf55

Previous GeneCards Identifiers for FAM110A Gene

  • GC20P000762

Summaries for FAM110A Gene

GeneCards Summary for FAM110A Gene

FAM110A (Family With Sequence Similarity 110, Member A) is a Protein Coding gene. Among its related pathways are Hemostasis and Formation of Fibrin Clot (Clotting Cascade). An important paralog of this gene is FAM110C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM110A Gene

Genomics for FAM110A Gene

Regulatory Elements for FAM110A Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM110A Gene

Start:
833,697 bp from pter
End:
857,463 bp from pter
Size:
23,767 bases
Orientation:
Plus strand

Genomic View for FAM110A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM110A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM110A Gene

Proteins for FAM110A Gene

  • Protein details for FAM110A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQ89-F110A_HUMAN
    Recommended name:
    Protein FAM110A
    Protein Accession:
    Q9BQ89
    Secondary Accessions:
    • D3DVW2
    • Q5R1M7

    Protein attributes for FAM110A Gene

    Size:
    295 amino acids
    Molecular mass:
    31271 Da
    Quaternary structure:
    • May interact with CSPP1.

neXtProt entry for FAM110A Gene

Proteomics data for FAM110A Gene at MOPED

Post-translational modifications for FAM110A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM110A Gene

Domains for FAM110A Gene

Protein Domains for FAM110A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM110A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BQ89

UniProtKB/Swiss-Prot:

F110A_HUMAN :
  • Q9BQ89
Family:
  • Belongs to the FAM110 family.
genes like me logo Genes that share domains with FAM110A: view

No data available for Gene Families for FAM110A Gene

Function for FAM110A Gene

Molecular function for FAM110A Gene

UniProtKB/Swiss-Prot Induction: Up-regulated in stimulated lymphocytes.

Gene Ontology (GO) - Molecular Function for FAM110A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 17474147
genes like me logo Genes that share ontologies with FAM110A: view

Animal Model Products

CRISPR Products

miRNA for FAM110A Gene

miRTarBase miRNAs that target FAM110A

No data available for Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM110A Gene

Localization for FAM110A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM110A Gene

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cytoplasm during mitosis, accumulating at spindle poles.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM110A Gene COMPARTMENTS Subcellular localization image for FAM110A gene
Compartment Confidence
cytoskeleton 5
mitochondrion 2
cytosol 1
extracellular 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM110A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000922 spindle pole IEA --
GO:0005737 cytoplasm IEA --
GO:0005815 microtubule organizing center IEA --
GO:0005856 cytoskeleton --
genes like me logo Genes that share ontologies with FAM110A: view

Pathways for FAM110A Gene

genes like me logo Genes that share pathways with FAM110A: view

Gene Ontology (GO) - Biological Process for FAM110A Gene

None

Transcripts for FAM110A Gene

Unigene Clusters for FAM110A Gene

Family with sequence similarity 110, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM110A

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM110A Gene

No ASD Table

Relevant External Links for FAM110A Gene

GeneLoc Exon Structure for
FAM110A
ECgene alternative splicing isoforms for
FAM110A

Expression for FAM110A Gene

mRNA expression in normal human tissues for FAM110A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM110A Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (6.8), Skin - Not Sun Exposed (Suprapubic) (6.0), Whole Blood (5.8), and Esophagus - Mucosa (4.1).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for FAM110A Gene

SOURCE GeneReport for Unigene cluster for FAM110A Gene Hs.574822

mRNA Expression by UniProt/SwissProt for FAM110A Gene

Q9BQ89-F110A_HUMAN
Tissue specificity: Detected in thyroid, lymph node, trachea, adrenal gland, bone marrow, spleen, thymus, prostate, and peripheral blood leukocyte. Detected at lower levels in stomach, testis and spinal cord.
genes like me logo Genes that share expressions with FAM110A: view

In Situ Assay Products

Orthologs for FAM110A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM110A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM110A 35
  • 97.63 (n)
  • 98.31 (a)
FAM110A 36
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM110A 35
  • 85.49 (n)
  • 91.5 (a)
FAM110A 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM110A 35
  • 86.67 (n)
  • 91.19 (a)
FAM110A 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam110a 35
  • 81.13 (n)
  • 85.76 (a)
Fam110a 16
Fam110a 36
  • 85 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam110a 35
  • 80.9 (n)
  • 86.1 (a)
chicken
(Gallus gallus)
Aves FAM110A 35
  • 66.55 (n)
  • 62.59 (a)
FAM110A 36
  • 50 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM110A 36
  • 45 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii fam110a 36
  • 38 (a)
OneToOne
wu:fa11c10 35
  • 61.8 (n)
  • 58.85 (a)
Species with no ortholog for FAM110A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM110A Gene

ENSEMBL:
Gene Tree for FAM110A (if available)
TreeFam:
Gene Tree for FAM110A (if available)

Paralogs for FAM110A Gene

Paralogs for FAM110A Gene

Selected SIMAP similar genes for FAM110A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM110A: view

Variants for FAM110A Gene

Sequence variations from dbSNP and Humsavar for FAM110A Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type MAF
rs482881 -- 837,047(+) ATTGt(G/T)ttttt intron-variant
rs486515 -- 837,432(+) GCTGA(C/T)GAAGC intron-variant
rs516685 -- 838,387(+) GGTGG(C/G)CTGGG intron-variant
rs519326 -- 832,087(+) CCTAG(A/C)AATTC upstream-variant-2KB
rs521990 -- 841,832(+) CCGCT(C/G)CACCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM110A Gene

Variant ID Type Subtype PubMed ID
nsv912580 CNV Gain 21882294
nsv912581 CNV Loss 21882294
nsv510778 CNV Loss 20534489

Relevant External Links for FAM110A Gene

HapMap Linkage Disequilibrium report
FAM110A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM110A Gene

Disorders for FAM110A Gene

No disorders were found for FAM110A Gene.

No data available for UniProtKB/Swiss-Prot for FAM110A Gene

Publications for FAM110A Gene

  1. Characterization of the FAM110 gene family. (PMID: 17499476) Hauge H. … Aasheim H.-C. (Genomics 2007) 2 3 4
  2. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 3 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  4. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  5. Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PMID: 17474147) Wu C. … Li S.S. (Proteomics 2007) 3

Products for FAM110A Gene

Sources for FAM110A Gene

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