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Aliases for FAM110A Gene

Aliases for FAM110A Gene

  • Family With Sequence Similarity 110 Member A 2 3 5
  • Family With Sequence Similarity 110, Member A 2 3
  • C20orf55 3 4
  • F10 3 4
  • Chromosome 20 Open Reading Frame 55 2
  • BA371L19.3 3

External Ids for FAM110A Gene

Previous HGNC Symbols for FAM110A Gene

  • C20orf55

Previous GeneCards Identifiers for FAM110A Gene

  • GC20P000762

Summaries for FAM110A Gene

GeneCards Summary for FAM110A Gene

FAM110A (Family With Sequence Similarity 110 Member A) is a Protein Coding gene. An important paralog of this gene is FAM110C.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM110A Gene

Genomics for FAM110A Gene

Regulatory Elements for FAM110A Gene

Enhancers for FAM110A Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FAM110A on UCSC Golden Path with GeneCards custom track

Promoters for FAM110A Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around FAM110A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM110A Gene

Chromosome:
20
Start:
833,697 bp from pter
End:
857,463 bp from pter
Size:
23,767 bases
Orientation:
Plus strand

Genomic View for FAM110A Gene

Genes around FAM110A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM110A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM110A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM110A Gene

Proteins for FAM110A Gene

  • Protein details for FAM110A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQ89-F110A_HUMAN
    Recommended name:
    Protein FAM110A
    Protein Accession:
    Q9BQ89
    Secondary Accessions:
    • D3DVW2
    • Q5R1M7

    Protein attributes for FAM110A Gene

    Size:
    295 amino acids
    Molecular mass:
    31271 Da
    Quaternary structure:
    • May interact with CSPP1.

neXtProt entry for FAM110A Gene

Proteomics data for FAM110A Gene at MOPED

Post-translational modifications for FAM110A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM110A Gene

Domains & Families for FAM110A Gene

Protein Domains for FAM110A Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM110A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q9BQ89

UniProtKB/Swiss-Prot:

F110A_HUMAN :
  • Belongs to the FAM110 family.
Family:
  • Belongs to the FAM110 family.
genes like me logo Genes that share domains with FAM110A: view

No data available for Gene Families for FAM110A Gene

Function for FAM110A Gene

Molecular function for FAM110A Gene

UniProtKB/Swiss-Prot Induction:
Up-regulated in stimulated lymphocytes.

Phenotypes for FAM110A Gene

GenomeRNAi human phenotypes for FAM110A:
genes like me logo Genes that share phenotypes with FAM110A: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM110A Gene

Localization for FAM110A Gene

Subcellular locations from UniProtKB/Swiss-Prot for FAM110A Gene

Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Distributed throughout the cytoplasm during mitosis, accumulating at spindle poles.

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM110A Gene COMPARTMENTS Subcellular localization image for FAM110A gene
Compartment Confidence
cytoskeleton 3
mitochondrion 2
cytosol 1
extracellular 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for FAM110A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005737 cytoplasm IEA --
genes like me logo Genes that share ontologies with FAM110A: view

Pathways & Interactions for FAM110A Gene

SuperPathways for FAM110A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM110A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM110A Gene

Drugs & Compounds for FAM110A Gene

No Compound Related Data Available

Transcripts for FAM110A Gene

Unigene Clusters for FAM110A Gene

Family with sequence similarity 110, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM110A Gene

No ASD Table

Relevant External Links for FAM110A Gene

GeneLoc Exon Structure for
FAM110A
ECgene alternative splicing isoforms for
FAM110A

Expression for FAM110A Gene

mRNA expression in normal human tissues for FAM110A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FAM110A Gene

This gene is overexpressed in Skin - Sun Exposed (Lower leg) (x6.8), Skin - Not Sun Exposed (Suprapubic) (x6.0), Whole Blood (x5.8), and Esophagus - Mucosa (x4.1).

Protein differential expression in normal tissues from HIPED for FAM110A Gene

This gene is overexpressed in Placenta (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for FAM110A Gene



SOURCE GeneReport for Unigene cluster for FAM110A Gene Hs.574822

mRNA Expression by UniProt/SwissProt for FAM110A Gene

Q9BQ89-F110A_HUMAN
Tissue specificity: Detected in thyroid, lymph node, trachea, adrenal gland, bone marrow, spleen, thymus, prostate, and peripheral blood leukocyte. Detected at lower levels in stomach, testis and spinal cord.
genes like me logo Genes that share expression patterns with FAM110A: view

Protein tissue co-expression partners for FAM110A Gene

- Elite partner

Primer Products

Orthologs for FAM110A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM110A Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM110A 35
  • 85.49 (n)
  • 91.5 (a)
FAM110A 36
  • 91 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM110A 35
  • 86.67 (n)
  • 91.19 (a)
FAM110A 36
  • 91 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam110a 35
  • 81.13 (n)
  • 85.76 (a)
Fam110a 16
Fam110a 36
  • 85 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM110A 35
  • 97.63 (n)
  • 98.31 (a)
FAM110A 36
  • 96 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam110a 35
  • 80.9 (n)
  • 86.1 (a)
chicken
(Gallus gallus)
Aves FAM110A 35
  • 66.55 (n)
  • 62.59 (a)
FAM110A 36
  • 50 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM110A 36
  • 45 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii wu:fa11c10 35
  • 61.8 (n)
  • 58.85 (a)
fam110a 36
  • 38 (a)
OneToOne
Species with no ortholog for FAM110A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for FAM110A Gene

ENSEMBL:
Gene Tree for FAM110A (if available)
TreeFam:
Gene Tree for FAM110A (if available)

Paralogs for FAM110A Gene

Paralogs for FAM110A Gene

(1) SIMAP similar genes for FAM110A Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with FAM110A: view

Variants for FAM110A Gene

Sequence variations from dbSNP and Humsavar for FAM110A Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs6055290 - 845,654(+) ATGGG(A/C)TAAGG reference, missense
rs482881 -- 837,047(+) ATTGt(G/T)ttttt intron-variant
rs486515 -- 837,432(+) GCTGA(C/T)GAAGC intron-variant
rs516685 -- 838,387(+) GGTGG(C/G)CTGGG intron-variant
rs519326 -- 832,087(+) CCTAG(A/C)AATTC upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM110A Gene

Variant ID Type Subtype PubMed ID
nsv912580 CNV Gain 21882294
nsv912581 CNV Loss 21882294
nsv510778 CNV Loss 20534489

Variation tolerance for FAM110A Gene

Gene Damage Index Score: 2.49; 43.69% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FAM110A Gene

Disorders for FAM110A Gene

Relevant External Links for FAM110A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM110A

No disorders were found for FAM110A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM110A Gene

Publications for FAM110A Gene

  1. Characterization of the FAM110 gene family. (PMID: 17499476) Hauge H. … Aasheim H.-C. (Genomics 2007) 2 3 4 67
  2. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  3. Interlaboratory reproducibility of large-scale human protein-complex analysis by standardized AP-MS. (PMID: 23455922) Varjosalo M. … Superti-Furga G. (Nat. Methods 2013) 3
  4. Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population. (PMID: 23251661) Comuzzie A.G. … Butte N.F. (PLoS ONE 2012) 3
  5. Next-generation sequencing to generate interactome datasets. (PMID: 21516116) Yu H. … Vidal M. (Nat. Methods 2011) 3

Products for FAM110A Gene

Sources for FAM110A Gene

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