FAM110A Gene
protein-coding GIFtS: 44
GCID: GC20P000762
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family with sequence similarity 110, member A(Previous name: chromosome 20 open reading frame 55 )
(Previous symbol: C20orf55)
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Aliases
for FAM110A gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Family With Sequence Similarity 110, Member A1 2 | | C20orf551 2 3 | | BA371L19.31 | | F102 3 | | Chromosome 20 Open Reading Frame 551 | | Protein FAM110A2 |
Export aliases for FAM110A gene to outside databases |
Summaries
for FAM110A gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for FAM110A gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000020.10 NC_018931.1 NT_011387.8
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the FAM110A gene promoter:
CREB deltaCREB p300 Cart-1 E47
Other transcription factors
Search SABiosciences Chromatin IP Primers for FAM110A
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM110A |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 20p13 Ensembl cytogenetic band: 20p13 HGNC cytogenetic band: 20p13FAM110A Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 20 GeneLoc Exon Structure GeneLoc location for GC20P000762: view genomic region
(about GC identifiers)
Start:
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814,356 bp from pter |
End:
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826,922 bp from pter |
Size:
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12,567 bases |
Orientation:
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plus strand |
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Proteins
for FAM110A gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: F110A_HUMAN, Q9BQ89 (See
protein sequence)Recommended Name: Protein FAM110A Size: 295 amino acids; 31271 Da
Subunit: May interact with CSPP1 (Potential)
Subcellular location: Cytoplasm. Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole.Note=Distributed throughout the cytoplasm during mitosis, accumulating at spindle poles
Developmental stage: During the cell cycle, expression is increased during S phase and G2/M phase
Secondary accessions: D3DVW2 Q5R1M7Explore the universe of human proteins at neXtProt for FAM110A: NX_Q9BQ89
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q9BQ89
FAM110A Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001035812.1 NP_113612.1 NP_997004.1
ENSEMBL proteins: ENSP00000371367 ENSP00000354163 ENSP00000371365 ENSP00000246100 ENSP00000445228
Human Recombinant Protein Products for FAM110A:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
FAM110A for ontologies About GeneDecksing
FAM110A Antibody Products:
Assay Products for FAM110A: |
Protein
Domains /
Families
for FAM110A gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
FAM110A for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q9BQ89ProtoNet protein and cluster: Q9BQ89 UniProtKB/Swiss-Prot: F110A_HUMAN, Q9BQ89Similarity: Belongs to the FAM110 family |
Function
for FAM110A gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: F110A_HUMAN, Q9BQ89Induction: Up-regulated in stimulated lymphocytes Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
FAM110A for ontologies About GeneDecksing
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM110A (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM110A (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): FAM110A (NM_031424) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM110A | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM110A |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM110A |
|
Pathways & Interactions
for FAM110A gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM110A
STRING Interaction
Network Preview (showing 5 interactants - click image to see more details)
5/6 Interacting proteins for FAM110A (Q9BQ891, 2, 3 ENSP000002461004) via UniProtKB, MINT, STRING, and/or I2D (see all 6)About this table
|
Drugs & Compounds
for FAM110A gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for FAM110A
Search CenterWatch for drugs/clinical trials and news about FAM110A / F110A
|
Transcripts
for FAM110A gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for FAM110A gene (3 alternative transcripts): NM_001042353.1 NM_031424.4 NM_207121.3 Unigene Cluster for FAM110A: Family with sequence similarity 110, member A Hs.574822 [show with all ESTs]Unigene Representative Sequence: NM_0010423535 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000381941(uc002wef.1) ENST00000304189 ENST00000381939 ENST00000246100(uc002weg.1)
ENST00000541082(uc002weh.1)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM110A (see all 6)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM110A (see all 3)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 3): FAM110A (NM_031424) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM110A | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM110A |
Additional cDNA sequence: AB196290.1 AJ293411.1 AK314165.1 BC004222.2 BC012800.2 BC022238.1 DQ431181.1 11 DOTS entries: DT.211076 DT.95075452 DT.91745633 DT.100041886 DT.100784276 DT.100649071 DT.100694425 DT.95278295 DT.100728409 DT.91723867 DT.92029805 24/119 AceView cDNA sequences (see all 119): AA362478 CR623946 CR593574 CR613912 AA830101 CR599968 BQ053386 CR590220 AI491808 CR615581 CR614477 AA552147 AA478326 BX354612 BM843846 BI910519 AI818675 CF785911 BC004222 AL522437 BU542855 BG680979 AW409592 BX333437
GeneLoc Exon Structure
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Expression
for FAM110A gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| FAM110A expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AGTGTACTCC
About this image
See FAM110A Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for FAM110A
SOURCE GeneReport for Unigene cluster: Hs.574822
UniProtKB/Swiss-Prot: F110A_HUMAN, Q9BQ89Tissue specificity: Detected in thyroid, lymph node, trachea, adrenal gland, bone marrow, spleen, thymus, prostate, andperipheral blood leukocyte. Detected at lower levels in stomach, testis and spinal cord
SABiosciences Custom PCR Arrays for FAM110A
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM110A
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FAM110A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM110A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM110A | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM110A |
Orthologs
for FAM110A gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for FAM110A gene from 3/8 species (see all 8) About this table
ENSEMBL Gene Tree for FAM110A (if available)
TreeFam Gene Tree for FAM110A (if available) |
Paralogs
for FAM110A gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for FAM110A gene
- FAM110D2 FAM110B2 FAM110C2
1 SIMAP similar gene for FAM110A using alignment to 1 protein entry: F110A_HUMAN:FAM110B
FAM110A for paralogs About GeneDecksing
|
Genomic Variants
for FAM110A gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 20 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for FAM110A (814356 - 826922 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for FAM110A: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM110A |
|
Disorders
/ Diseases
for FAM110A gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
FAM110A for disorders About GeneDecksing
OMIM gene information: 611393
OMIM disorders: --
2  diseases for FAM110A: About MalaCardsthyroiditis prostatitis
Export disorders for FAM110A gene to outside databases
|
Publications
for FAM110A gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for FAM110A gene integrated from 9 sources:
(articles sorted by number of sources associating them with FAM110A) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the FAM110 gene family. (PubMed id 17499476)1, 2, 3 Hauge H.... Aasheim H.-C. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and comparative analysis of human chromosome 20. (PubMed id 11780052)1, 2 Deloukas P....Rogers J. (2001)
- A directed protein interaction network for investigat ing intracellular signal transduction. (PubMed id 21900206)1 Vinayagam A....Wanker E.E. (2011)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- Systematic identification of SH3 domain-mediated human protein-protein interactions by peptide array target screening. (PubMed id 17474147)1 Wu C....Li S.S. (2007)
- Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
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External Searches for FAM110A gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
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Genome Databases showing FAM110A gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing FAM110A gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAM110A gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for FAM110A | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for FAM110A gene:
Search GeneIP for patents involving FAM110A
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for FAM110A gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for FAM110A | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAM110A | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FAM110A | | | OriGene Protein Over-expression Lysate for FAM110A | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for FAM110A | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAM110A | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FAM110A | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for FAM110A | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for FAM110A | | OriGene Custom Protein Services for FAM110A | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM110A | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAM110A | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAM110A | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAM110A | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAM110A | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAM110A |
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| | | | Search Tocris compounds for FAM110A |
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 | | | FAM110A Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM110A |
|  |  |  |  | | | | Search ThermoFisher Antibodies for FAM110A |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM110A |
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