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FAM109B Gene

protein-coding   GIFtS: 44
GCID: GC22P042470

Family With Sequence Similarity 109, Member B

  Search for FAM109B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 109, Member B1 2
IPIP27B2 3 5
27 KDa Inositol Polyphosphate Phosphatase Interacting Protein B2 3
Ses22 3
sesquipedalian-22
SES25

External Ids:    HGNC: 271611   Entrez Gene: 1503682   Ensembl: ENSG000001770967   OMIM: 6142405   UniProtKB: Q6ICB43   

Export aliases for FAM109B gene to outside databases

Previous GC identifers: GC22P040795 GC22P025436


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM109B Gene:
FAM109B (family with sequence similarity 109, member B) is a protein-coding gene. GO annotations related to this gene include phospholipid binding and protein homodimerization activity. An important paralog of this gene is FAM109A.

UniProtKB/Swiss-Prot: SESQ2_HUMAN, Q6ICB4
Function: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the
trans-Golgi network and the plasma membrane




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000022.11  NT_011520.13  NC_018933.2  NT_187682.1  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM109B gene promoter:
         GR   Max1   AML1a   MyoD   c-Myb   GR-alpha   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM109B promoter sequence
   Search Chromatin IP Primers for FAM109B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM109B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 22q13.2   Ensembl cytogenetic band:  22q13.2   HGNC cytogenetic band: 22q13.2

FAM109B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM109B gene location

GeneLoc information about chromosome 22         GeneLoc Exon Structure

GeneLoc location for GC22P042470:  view genomic region     (about GC identifiers)

Start:
42,470,255 bp from pter      End:
42,475,445 bp from pter
Size:
5,191 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: SESQ2_HUMAN, Q6ICB4 (See protein sequence)
Recommended Name: Sesquipedalian-2  
Size: 259 amino acids; 28338 Da
Subunit: Forms homodimers and heterodimers with FAM109A. Interacts with OCRL and INPP5B
Miscellaneous: Was named after 'sesquipedalian', an unnecessarily long description of a simple thing
(PubMed:20133602)
Secondary accessions: Q3SXQ3 Q8N6L9

Explore the universe of human proteins at neXtProt for FAM109B: NX_Q6ICB4

Explore proteomics data for FAM109B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM109B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001002034.2  
    ENSEMBL proteins: 
     ENSP00000312753   ENSP00000396170  

    FAM109B Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for FAM109B

     
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    Search LSBio for Antibodies for FAM109B

    FAM109B Assay Products:

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    Cloud-Clone Corp. ELISAs for FAM109B
    Cloud-Clone Corp. CLIAs for FAM109B
    Search eBioscience for ELISAs for FAM109B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    PLEKH: Pleckstrin homology (PH) domain containing

    2 InterPro protein domains:
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom

    Graphical View of Domain Structure for InterPro Entry Q6ICB4

    ProtoNet protein and cluster: Q6ICB4

    1 Blocks protein domain: IPB001849 Pleckstrin-like

    UniProtKB/Swiss-Prot: SESQ2_HUMAN, Q6ICB4
    Domain: The F&H motif, an approximately 12-13 amino-acid sequence centered around Phe and His residues, is
    essential for binding to OCRL and INPP5B
    Similarity: Belongs to the sesquipedalian family
    Similarity: Contains 1 PH domain


    Find genes that share domains with FAM109B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: SESQ2_HUMAN, Q6ICB4
    Function: Plays a role in endocytic trafficking. Required for receptor recycling from endosomes, both to the
    trans-Golgi network and the plasma membrane

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI--
    GO:0042803protein homodimerization activity IPI--
         
    Find genes that share ontologies with FAM109B           About GenesLikeMe


    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM109B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM109B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM109B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM109B

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM109B:
    hsa-mir-29a-3p (MIRT049987), hsa-mir-193b-3p (MIRT016331), hsa-mir-124-3p (MIRT022341)

    Block miRNA regulation of human, mouse, rat FAM109B using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate FAM109B:
    hsa-miR-4254 hsa-miR-1260b hsa-miR-1260 hsa-miR-619 hsa-miR-1291 hsa-miR-490-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM109B 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat FAM109B

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    Browse Sino Biological Human cDNA Clones
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM109B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    SESQ2_HUMAN, Q6ICB4: Early endosome. Recycling endosome. Golgi apparatus, trans-Golgi network. Cytoplasmic
    vesicle, clathrin-coated vesicle. Note=Also found on macropinosomes. Not detected in late endosomes, nor in
    lysosomes
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    endosome5
    cytosol3
    golgi apparatus3
    nucleus2
    extracellular1
    mitochondrion1

    Gene Ontology (GO): 5 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005769early endosome IDA--
    GO:0005794Golgi apparatus IEA--
    GO:0005802trans-Golgi network IDA--
    GO:0030136clathrin-coated vesicle IDA--
    GO:0055037recycling endosome IDA--

    Find genes that share ontologies with FAM109B           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM109B
    Interactions:

        Search GeneGlobe Interaction Network for FAM109B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 22)

    Selected Interacting proteins for FAM109B (Q6ICB43 ENSP000003127534) via UniProtKB, MINT, STRING, and/or I2D (see all 28)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    OCRLQ019683, ENSP000003601544I2D: score=1 STRING: ENSP00000360154
    FRMPD4Q14CM03I2D: score=4 
    INPP5BP320193I2D: score=4 
    SNX33Q8WV413I2D: score=4 
    ZW10O432643I2D: score=4 
    About this table

    Gene Ontology (GO): 3 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001881receptor recycling IMP--
    GO:0007032endosome organization IMP--
    GO:0042147retrograde transport, endosome to Golgi IMP--

    Find genes that share ontologies with FAM109B           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM109B (SESQ2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM109B gene: 
    NM_001002034.2  

    Unigene Cluster for FAM109B:

    Family with sequence similarity 109, member B
    Hs.368312  [show with all ESTs]
    Unigene Representative Sequence: BX648402
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000321753(uc003bbz.3) ENST00000419475
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM109B using miScript Target Protectors
    6 qRT-PCR Assays for microRNAs that regulate FAM109B:
    hsa-miR-4254 hsa-miR-1260b hsa-miR-1260 hsa-miR-619 hsa-miR-1291 hsa-miR-490-3p
    SwitchGear 3'UTR luciferase reporter plasmidFAM109B 3' UTR sequence
    Inhib. RNA
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    OriGene RNAi products in human, mouse, rat for FAM109B
    Predesigned siRNA for gene silencing in human, mouse, rat FAM109B
    Clone
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    GenScript: all cDNA clones in your preferred vector: FAM109B (NM_001002034)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM109B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM109B
    Primer
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    OriGene qSTAR qPCR primer pairs in human, mouse for FAM109B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM109B
      QuantiTect SYBR Green Assays in human, mouse, rat FAM109B
      QuantiFast Probe-based Assays in human, mouse, rat FAM109B

    Additional mRNA sequence: 

    BC029776.1 BC104175.1 BC104176.1 BX648402.1 CR456454.1 

    2 DOTS entries:

    DT.101970206  DT.100781341 

    Selected AceView cDNA sequences (see all 110):

    AI673098 AW075393 CN481747 BQ067666 CN482518 AI143091 BU622835 BU727322 
    CR605425 BU069299 BX110542 BM716594 AI869422 BX371152 AA308225 CA433435 
    AI269068 CR600979 BX347933 BX386225 BX403238 BM503822 AI221367 BI761027 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM109B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGTTCTCTCC
    FAM109B Expression
    About this image


    FAM109B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Paraxial Mesoderm (Gastrulation Derivatives)
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     Neural Crest (Gastrulation Derivatives)
             PureStem 7PEND24, NCr-fac & Meso-prx Progenitor
     
     Heart (Cardiovascular System)
    FAM109B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM109B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.368312
        Custom PCR Arrays for FAM109B
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM109B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for FAM109B gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam109b1 , 5 family with sequence similarity 109, member B1, 5 80.57(n)1
    78.38(a)1
      15 (38.56 cM)5
    3383681  NM_177391.41  NP_796365.11 
     823389425 
    chicken
    (Gallus gallus)
    Aves FAM109B6
    family with sequence similarity 109, member B
    49(a)
    1 ↔ 1
    1(49282567-49284391)
    lizard
    (Anolis carolinensis)
    Reptilia FAM109B6
    family with sequence similarity 109, member B
    49(a)
    1 ↔ 1
    5(27085301-27086080)
    zebrafish
    (Danio rerio)
    Actinopterygii zgc:1537336
    zgc:153733
    25(a)
    many ↔ many
    3(32962285-32968947) ENSDARG00000053257
    fruit fly
    (Drosophila melanogaster)
    Insecta CG123936
    --
    20(a)
    1 → many
    2L(6047999-6050474)


    ENSEMBL Gene Tree for FAM109B (if available)
    TreeFam Gene Tree for FAM109B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM109B gene
    FAM109A2  
    1 SIMAP similar gene for FAM109B using alignment to 2 protein entries:     SESQ2_HUMAN (see all proteins):
    FAM109A

    Find genes that share paralogs with FAM109B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM109B (see all 92)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 22 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1333801,2
    C,F,A,H--42468910(+) catctC/Tgcctg 1 -- us2k124Minor allele frequency- T:0.47MN NS EA NA WA 2700
    rs1914331561,2
    --42469095(+) TGTCTA/GCCCCT 1 -- us2k10--------
    rs1837479601,2
    --42469272(+) ACTCTA/GTTTGC 1 -- us2k10--------
    rs774683401,2
    C,F--42469694(+) GAGGAC/TACCTC 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs1392659381,2
    --42469766(+) TTCACC/TGCAGG 1 -- us2k10--------
    rs1878877111,2
    --42469868(+) TCAGCC/TGACCC 1 -- us2k10--------
    rs412774811,2
    C--42470063(+) GCCCGC/TGGACC 1 -- us2k10--------
    rs57512101,2
    C,F--42470074(+) GTCCGA/TGGGGG 1 -- us2k11Minor allele frequency- T:0.47EA 120
    rs1915524631,2
    --42470075(+) TCCGAA/GGGGGG 1 -- us2k10--------
    rs761435701,2
    C,F--42470107(+) GCACCG/AACCAG 1 -- us2k11Minor allele frequency- A:0.11WA 118

    HapMap Linkage Disequilibrium report for FAM109B (42470255 - 42475445 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for FAM109B:    About this table    
    Variant IDTypeSubtypePubMed ID
    nsv508737CNV Insertion20534489
    dgv4981n71CNV Loss21882294
    nsv834210CNV Loss17160897
    nsv915161CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM109B
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM109B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 614240    OMIM disorders: --


    Find genes that share disorders with FAM109B           About GenesLikeMe


    Export disorders for FAM109B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM109B gene integrated from 10 sources:
    (articles sorted by number of sources associating them with FAM109B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The PH domain proteins IPIP27A and B link OCRL1 to receptor recycling in the endocytic pathway. (PubMed id 21233288)1, 2 Noakes C.J.... Lowe M. (Mol. Biol. Cell 2011)
    2. Two closely related endocytic proteins that share a common OCRL- binding motif with APPL1. (PubMed id 20133602)1, 2 Swan L.E.... De Camilli P. (Proc. Natl. Acad. Sci. U.S.A. 2010)
    3. A genome annotation-driven approach to cloning the human ORFeome. (PubMed id 15461802)1, 2 Collins J.E.... Dunham I. (Genome Biol. 2004)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1, 3 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    6. The DNA sequence of human chromosome 22. (PubMed id 10591208)1, 2 Dunham I.... Wright H. (Nature 1999)
    7. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 150368 HGNC: 27161 AceView: LOC150368 Ensembl:ENSG00000177096 euGenes: HUgn150368
    ECgene: FAM109B H-InvDB: FAM109B

    (According to HUGE)
    About This Section

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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for FAM109B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM109B gene:
    Search GeneIP for patents involving FAM109B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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