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FAM107B Gene

protein-coding   GIFtS: 50
GCID: GC10M014471

Family With Sequence Similarity 107, Member B

(Previous name: chromosome 10 open reading frame 45)
(Previous symbol: C10orf45)
  Search for FAM107B
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Family With Sequence Similarity 107, Member B1 2
C10orf451 2 3
Chromosome 10 Open Reading Frame 451
Protein FAM107B2

External Ids:    HGNC: 237261   Entrez Gene: 836412   Ensembl: ENSG000000658097   UniProtKB: Q9H0983   

Export aliases for FAM107B gene to outside databases

Previous GC identifer: GC10M014601


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM107B Gene:
FAM107B (family with sequence similarity 107, member B) is a protein-coding gene. An important paralog of this gene is FAM107A.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000010.10  NT_008705.17  NC_018921.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM107B gene promoter:
         SRF   Sox5   RREB-1   SRF (504 AA)   Ik-3   Arnt   MEF-2A   FAC1   SRY   aMEF-2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): FAM107B promoter sequence
   Search Chromatin IP Primers for FAM107B

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM107B


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10p13   Ensembl cytogenetic band:  10p13   HGNC cytogenetic band: 10p14

FAM107B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM107B gene location

GeneLoc information about chromosome 10         GeneLoc Exon Structure

GeneLoc location for GC10M014471:  view genomic region     (about GC identifiers)

Start:
14,560,556 bp from pter      End:
14,816,896 bp from pter
Size:
256,341 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: F107B_HUMAN, Q9H098 (See protein sequence)
Recommended Name: Protein FAM107B  
Size: 131 amino acids; 15558 Da
Secondary accessions: A8K1P4 D3DRT2 Q5T9K7 Q5T9K8 Q6ZSI4
Alternative splicing: 2 isoforms:  Q9H098-1   Q9H098-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM107B: NX_Q9H098

Explore proteomics data for FAM107B at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See FAM107B Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (10 alternative transcripts): 
    NP_001269624.1  NP_001269625.1  NP_001269626.1  NP_001269627.1  NP_001269628.1  NP_001269629.1  NP_001269630.1  NP_001269631.1  
    NP_001269632.1  NP_113641.2  

    ENSEMBL proteins: 
     ENSP00000367731   ENSP00000181796   ENSP00000418120   ENSP00000367728   ENSP00000420273  
     ENSP00000367726   ENSP00000367719   ENSP00000417782   ENSP00000367723   ENSP00000418365  
     ENSP00000418330   ENSP00000419603   ENSP00000420444   ENSP00000413676   ENSP00000420249  
     ENSP00000418395   ENSP00000417242   ENSP00000420314   ENSP00000397949   ENSP00000417845  
     ENSP00000419064  

    FAM107B Human Recombinant Protein Products:

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    Browse Sino Biological Cell Lysates
    ProSpec Recombinant Protein for FAM107B
    Cloud-Clone Corp. Proteins for FAM107B

     
    Search eBioscience for Proteins for FAM107B 

    FAM107B Antibody Products:

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    Abcam antibodies for FAM107B
    Cloud-Clone Corp. Antibodies for FAM107B
    Search ThermoFisher Antibodies for FAM107B
    Search LSBio for Antibodies for FAM107B

    FAM107B Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FAM107B
    Cloud-Clone Corp. CLIAs for FAM107B
    Search eBioscience for ELISAs for FAM107B 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR009533 DUF1151

    Graphical View of Domain Structure for InterPro Entry Q9H098

    ProtoNet protein and cluster: Q9H098

    UniProtKB/Swiss-Prot: F107B_HUMAN, Q9H098
    Similarity: Belongs to the FAM107 family


    Find genes that share domains with FAM107B           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Phenotypes:
         2 GenomeRNAi human phenotypes for FAM107B:
     Cell division defect  Increased G2M DNA content 

         3 MGI mutant phenotypes (inferred from 1 allele(MGI details for Fam107b):
     cellular  hearing/vestibular/ear  skeleton 

    Find genes that share phenotypes with FAM107B           About GenesLikeMe

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM107B
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM107B

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM107B
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM107B

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAM107B:
    hsa-mir-615-3p (MIRT039777), hsa-mir-26b-5p (MIRT030175)

    Block miRNA regulation of human, mouse, rat FAM107B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM107B (see all 71):
    hsa-miR-579 hsa-miR-607 hsa-miR-300 hsa-miR-218-1* hsa-miR-3653 hsa-miR-371-5p hsa-miR-877* hsa-miR-890
    SwitchGear 3'UTR luciferase reporter plasmidFAM107B 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAM107B
    Predesigned siRNA for gene silencing in human, mouse, rat FAM107B

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for FAM107B

    Clone
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    OriGene clones in human, mouse for FAM107B (see all 7)
    OriGene ORF clones in mouse, rat for FAM107B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM107B (NM_031453)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM107B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM107B

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for FAM107B 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM107B


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    nucleus2

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM107B
    Interactions:

        Search GeneGlobe Interaction Network for FAM107B

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for FAM107B (Q9H0982, 3 ENSP000001817964) via UniProtKB, MINT, STRING, and/or I2D (see all 72)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    TADA3O755282, 3, ENSP000003076844MINT-63210 I2D: score=3 STRING: ENSP00000307684
    DEPDC1ENSP000004122924STRING: ENSP00000412292
    ARHGEF10LENSP000003550604STRING: ENSP00000355060
    ASPMENSP000003563794STRING: ENSP00000356379
    ATPAF1ENSP000003610054STRING: ENSP00000361005
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAM107B (F107B)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for FAM107B gene (10 alternative transcripts): 
    NM_001282695.1  NM_001282696.1  NM_001282697.1  NM_001282698.1  NM_001282699.1  NM_001282700.1  NM_001282701.1  NM_001282702.1  
    NM_001282703.1  NM_031453.3  

    Unigene Cluster for FAM107B:

    Family with sequence similarity 107, member B
    Hs.446315  [show with all ESTs]
    Unigene Representative Sequence: AK127413
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 28):
    ENST00000378470(uc001imx.1 uc009xjg.1 uc001imy.1 uc001imz.1)
    ENST00000181796(uc001ina.1 uc010qbu.1) ENST00000468747 ENST00000378467
    ENST00000487335 ENST00000378465 ENST00000378458 ENST00000478076 ENST00000378462
    ENST00000481209 ENST00000475858 ENST00000496330 ENST00000492700 ENST00000479731
    ENST00000468492 ENST00000452706 ENST00000489100 ENST00000494865
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAM107B using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate FAM107B (see all 71):
    hsa-miR-579 hsa-miR-607 hsa-miR-300 hsa-miR-218-1* hsa-miR-3653 hsa-miR-371-5p hsa-miR-877* hsa-miR-890
    SwitchGear 3'UTR luciferase reporter plasmidFAM107B 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAM107B
    Predesigned siRNA for gene silencing in human, mouse, rat FAM107B
    Clone
    Products:
         
    OriGene clones in human, mouse for FAM107B (see all 7)
    OriGene ORF clones in mouse, rat for FAM107B
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAM107B (NM_031453)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM107B
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM107B
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FAM107B
    OriGene qSTAR qPCR primer pairs in human, mouse for FAM107B
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM107B
      QuantiTect SYBR Green Assays in human, mouse, rat FAM107B
      QuantiFast Probe-based Assays in human, mouse, rat FAM107B

    Additional mRNA sequence: 

    AK024648.1 AK074275.1 AK123138.1 AK127413.1 AK289959.1 AL136885.1 BC004872.2 BC064407.1 
    BC072452.1 BC144707.1 CR533466.1 

    Selected DOTS entries (see all 25):

    DT.101971582  DT.418374  DT.100811911  DT.101967715  DT.95246385  DT.91698247  DT.95162228  DT.121270405 
    DT.121270445  DT.121270406  DT.121270439  DT.75145968  DT.91918113  DT.101971054  DT.100811906  DT.100708000 
    DT.100811914  DT.100811915  DT.121270429  DT.121270438  DT.75112888  DT.95222984  DT.95307695  DT.95324077 

    Selected AceView cDNA sequences (see all 342):

    AA027238 AI342573 BQ081984 BP369343 N73845 AW580903 AI276201 N52764 
    AI801534 BM463487 CB043884 BM792437 CB112674 CR620856 BM709087 R27914 
    AI804440 AA745752 BU074502 CF529990 AI587633 BP350275 AA453853 BX419408 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for FAM107B    About this scheme

    ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b · 9c
    SP1:                          -           -                                       
    SP2:              -     -     -     -     -                                       
    SP3:                          -     -     -                                       
    SP4:                                                                              
    SP5:                                -     -                                       


    ECgene alternative splicing isoforms for FAM107B

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FAM107B expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTAGTTGATT
    FAM107B Expression
    About this image


    FAM107B expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 8) fully expand
     
     Brain (Nervous System)    fully expand to see all 2 entries
             Cerebral Cortex
     
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
     
     Bone (Muscoskeletal System)
             Bone Marrow
     
     Lung (Respiratory System)
     
     Colon (Gastrointestinal Tract)
    FAM107B Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAM107B Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.446315
        Custom PCR Arrays for FAM107B
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FAM107B
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    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM107B
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    QuantiFast Probe-based Assays in human, mouse, rat FAM107B
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM107B

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FAM107B gene from Selected species (see all 11)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fam107b1 , 5 family with sequence similarity 107, member B1, 5 90.59(n)1
    98.47(a)1
      2 (2.05 cM)5
    665401  NM_025626.41  NP_079902.11 
     36137585 
    chicken
    (Gallus gallus)
    Aves FAM107B6
    family with sequence similarity 107, member B
    80(a)
    1 ↔ 1
    1(7160122-7169485)
    lizard
    (Anolis carolinensis)
    Reptilia FAM107B6
    family with sequence similarity 107, member B
    89(a)
    1 ↔ 1
    GL343559.1(44537-200091)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia fam107b1 family with sequence similarity 107, member B 73.54(n)
    73.28(a)
      493295  NM_001007912.2  NP_001007913.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc562162 zgc56216 76.63(n)   386641  AY391439.1 


    ENSEMBL Gene Tree for FAM107B (if available)
    TreeFam Gene Tree for FAM107B (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FAM107B gene
    FAM107A2  
    2 SIMAP similar genes for FAM107B using alignment to 10 protein entries:     F107B_HUMAN (see all proteins):
    FAM107A    TU3A

    Find genes that share paralogs with FAM107B           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FAM107B (see all 6380)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 10 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1495788841,2
    --14560098(+) CAGGCA/GTATAC 1 -- ds50010--------
    rs1907736391,2
    --14560206(+) TCAAAC/TGCACT 1 -- ds50010--------
    rs1113655381,2
    C,F--14560282(+) TTTGAG/ACTGAG 1 -- ds50012Minor allele frequency- A:0.04NA EA 240
    rs782448021,2
    F--14560330(+) TACTGC/AAATGT 1 -- ds50011Minor allele frequency- A:0.05NA 120
    rs727849251,2
    C,F--14560512(+) GCCCCG/ATTCTG 1 -- ds50011Minor allele frequency- A:0.02NA 120
    rs1442771301,2
    --14560525(+) CCAGAC/TGCACA 1 -- ds50010--------
    rs1821858591,2
    --14560599(+) AACTTC/TGGTTC 1 -- ut310--------
    rs1872696451,2
    --14560626(+) AATTCC/TTTAAT 1 -- ut310--------
    rs1891965291,2
    C--14560684(+) AATTAC/TGAAAA 1 -- ut310--------
    rs1154886351,2
    C,F--14560822(+) ATTAAA/GCTATT 1 -- ut311Minor allele frequency- G:0.03WA 118

    HapMap Linkage Disequilibrium report for FAM107B (14560556 - 14810556 bp, first 250kb of FAM107B)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for FAM107B (see all 22):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2733461CNV Deletion23290073
    esv3533CNV Deletion18987735
    esv2733439CNV Deletion23290073
    esv2733473CNV Deletion23290073
    esv1960476CNV Deletion18987734
    esv2733450CNV Deletion23290073
    esv2676128CNV Deletion23128226
    esv2658515CNV Deletion23128226
    esv1027578CNV Deletion17803354
    nsv5877CNV Insertion18451855

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FAM107B
    DNA2.0 Custom Variant and Variant Library Synthesis for FAM107B

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    Find genes that share disorders with FAM107B           About GenesLikeMe

    Genetic Association Database (GAD): FAM107B
    Human Genome Epidemiology (HuGE) Navigator: FAM107B (5 documents)

    Export disorders for FAM107B gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FAM107B gene, integrated from 10 sources (see all 22):
    (articles sorted by number of sources associating them with FAM107B)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2, 3 Wiemann S.... Poustka A. (Genome Res. 2001)
    2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    3. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    4. A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)1, 4 Grupe A....Goate A. (Am. J. Hum. Genet. 2006)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)1, 2 Deloukas P.... Rogers J. (Nature 2004)
    7. Bcl2-associated athanogene 3 interactome analysis reveals a new role in modulating proteasome activity. (PubMed id 23824909)1 Chen Y....Ge F. (amp 2013)
    8. Loss of HITS (FAM107B) expression in cancers of multiple organs: tissue microarray analysis. (PubMed id 22825356)1 Nakajima H....Motoo Y. (Int. J. Oncol. 2012)
    9. Systematic analysis of human protein complexes identifies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R.... Peters J.M. (Science 2010)
    10. Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach. (PubMed id 19413330)2 Gauci S....Mohammed S. (Anal. Chem. 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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      Query String
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 83641 HGNC: 23726 AceView: C10orf45 Ensembl:ENSG00000065809 euGenes: HUgn83641
    ECgene: FAM107B H-InvDB: FAM107B

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FAM107B Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for FAM107B gene:
    Search GeneIP for patents involving FAM107B

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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