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FAM107A Gene

protein-coding   GIFtS: 50
GCID: GC03M058549

Family With Sequence Similarity 107, Member A

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Family With Sequence Similarity 107, Member A1 2
DRR12 3 5
TU3A2 3 5
Down-Regulated In Renal Cell Carcinoma 12 3
Protein FAM107A2
Protein TU3A3

External Ids:    HGNC: 308271   Entrez Gene: 111702   Ensembl: ENSG000001683097   OMIM: 6082955   UniProtKB: O959903   
ORGUL members:         

Export aliases for FAM107A gene to outside databases

Previous GC identifer: GC03M058526


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for FAM107A Gene:
FAM107A (family with sequence similarity 107, member A) is a protein-coding gene. Diseases associated with FAM107A include renal cell carcinoma, and benign meningioma. An important paralog of this gene is FAM107B.

UniProtKB/Swiss-Prot: F107A_HUMAN, O95990
Function: When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role
in tumor development

Gene Wiki entry for FAM107A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NT_022517.19  NC_018914.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAM107A gene promoter:
         Oct-B1   AML1a   NRSF form 1   Pax-2   Pax-2a   NRSF form 2   Evi-1   Pax-2b   HSF2   FOXO4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAM107A promoter sequence
   Search Chromatin IP Primers for FAM107A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAM107A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p21.1   Ensembl cytogenetic band:  3p14.2   HGNC cytogenetic band: 3p14.2

FAM107A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAM107A gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M058549:  view genomic region     (about GC identifiers)

Start:
58,549,844 bp from pter      End:
58,613,337 bp from pter
Size:
63,494 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: F107A_HUMAN, O95990 (See protein sequence)
Recommended Name: Protein FAM107A  
Size: 144 amino acids; 17455 Da
Secondary accessions: Q96NH4
Alternative splicing: 2 isoforms:  O95990-1   O95990-2   (May be due to an intron retention. No experimental confirmation available)

Explore the universe of human proteins at neXtProt for FAM107A: NX_O95990

Explore proteomics data for FAM107A at MOPED


See FAM107A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (4 alternative transcripts): 
NP_001070246.1  NP_001269642.1  NP_001269643.1  NP_009108.1  

ENSEMBL proteins: 
 ENSP00000354270   ENSP00000377991   ENSP00000419529   ENSP00000419124   ENSP00000400858  
 ENSP00000418038  

FAM107A Human Recombinant Protein Products:

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Cloud-Clone Corp. Proteins for FAM107A

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LSBio Antibodies in human, mouse, rat for FAM107A

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Cloud-Clone Corp. CLIAs for FAM107A


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR009533 DUF1151

Graphical View of Domain Structure for InterPro Entry O95990

ProtoNet protein and cluster: O95990

UniProtKB/Swiss-Prot: F107A_HUMAN, O95990
Similarity: Belongs to the FAM107 family


FAM107A for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: F107A_HUMAN, O95990
Function: When transfected into cell lines in which it is not expressed, suppresses cell growth. May play a role
in tumor development

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003674molecular_function ND--
     
FAM107A for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAM107A
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAM107A

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAM107A
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAM107A

miRNA
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Block miRNA regulation of human, mouse, rat FAM107A using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FAM107A (see all 14):
hsa-miR-194* hsa-miR-647 hsa-miR-34c-5p hsa-miR-516b hsa-miR-449b hsa-miR-449a hsa-miR-3921 hsa-miR-182
SwitchGear 3'UTR luciferase reporter plasmidFAM107A 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for FAM107A
Predesigned siRNA for gene silencing in human, mouse, rat FAM107A

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for FAM107A

Clone
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OriGene clones in human, mouse for FAM107A (see all 13)
OriGene ORF clones in mouse, rat for FAM107A
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GenScript: all cDNA clones in your preferred vector (see all 2): FAM107A (NM_007177)
Sino Biological Human cDNA Clone for FAM107A
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM107A
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM107A

Cell Line
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In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM107A


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
F107A_HUMAN, O95990: Nucleus
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
cytosol2

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA10564580

FAM107A for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAM107A
Interactions:

    Search GeneGlobe Interaction Network for FAM107A

STRING Interaction Network Preview (showing 5 interactants - click image to see 24)

Selected Interacting proteins for FAM107A (O959901, 2, 3 ENSP000003542704) via UniProtKB, MINT, STRING, and/or I2D (see all 30)
InteractantInteraction Details
GeneCardExternal ID(s)
CCDC85BQ158342, 3, ENSP000003116954MINT-68129 I2D: score=5 STRING: ENSP00000311695
KRT15P190122, 3, ENSP000002540434MINT-67827 I2D: score=5 STRING: ENSP00000254043
NINLQ9Y2I62, 3, ENSP000002788864MINT-68263 I2D: score=5 STRING: ENSP00000278886
TRIM37O949722, 3, ENSP000002622944MINT-66452 I2D: score=5 STRING: ENSP00000262294
EFEMP2O959672, 3, ENSP000003099534MINT-66339 I2D: score=4 STRING: ENSP00000309953
About this table

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0001558regulation of cell growth IDA10564580

FAM107A for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for FAM107A (F107A)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for FAM107A gene (4 alternative transcripts): 
NM_001076778.2  NM_001282713.1  NM_001282714.1  NM_007177.3  

Unigene Cluster for FAM107A:

Family with sequence similarity 107, member A
Hs.506357  [show with all ESTs]
Unigene Representative Sequence: AF089854
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000360997(uc003dkn.3 uc010hnm.3 uc003dko.3) ENST00000394481(uc003dkm.3)
ENST00000464064(uc003dkp.1) ENST00000474531 ENST00000447756 ENST00000465970
ENST00000497310
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat FAM107A using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate FAM107A (see all 14):
hsa-miR-194* hsa-miR-647 hsa-miR-34c-5p hsa-miR-516b hsa-miR-449b hsa-miR-449a hsa-miR-3921 hsa-miR-182
SwitchGear 3'UTR luciferase reporter plasmidFAM107A 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for FAM107A
Predesigned siRNA for gene silencing in human, mouse, rat FAM107A
Clone
Products:
     
OriGene clones in human, mouse for FAM107A (see all 13)
OriGene ORF clones in mouse, rat for FAM107A
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): FAM107A (NM_007177)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAM107A
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAM107A
Primer
Products:
    
OriGene qPCR primer pairs and template standards for FAM107A
OriGene qSTAR qPCR primer pairs in human, mouse for FAM107A
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM107A
  QuantiTect SYBR Green Assays in human, mouse, rat FAM107A
  QuantiFast Probe-based Assays in human, mouse, rat FAM107A

Additional mRNA sequence: 

AB023811.1 AF035283.1 AF089853.1 AF089854.1 AK054720.1 AK055443.1 AK128791.1 AK298001.1 
AK316450.1 AL050264.1 BC010561.1 BC093012.1 CR457133.1 EU569833.1 

Selected DOTS entries (see all 25):

DT.100792271  DT.100792274  DT.40252339  DT.100792275  DT.95363147  DT.99988736  DT.95363151  DT.95363145 
DT.100775775  DT.40211893  DT.120887427  DT.120887491  DT.120887403  DT.120887399  DT.120887419  DT.120887493 
DT.95324091  DT.100792277  DT.120887379  DT.120887390  DT.120887452  DT.95187780  DT.97788160  DT.97863455 

Selected AceView cDNA sequences (see all 546):

BM974610 F11836 F09483 CR609117 BM672181 BU678354 BP346548 F09311 
AI243246 AA576178 AW161103 BP347636 AU121700 AI680022 BI912898 BP346877 
AI085326 BF725282 CD677908 Z40089 BM927069 BE504342 CK429986 BE255917 

GeneLoc Exon Structure

Selected Alternative Splicing Database (ASD) splice patterns (SP) for FAM107A (see all 14)    About this scheme

ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d ^ 8 ^ 9a · 9b · 9c · 9d · 9e ^ 10a · 10b · 10c · 10d ^ 11a · 11b · 11c ^ 12a ·
SP1:                                                                                                                                -                 -         
SP2:                          -           -     -     -     -     -     -     -                                                     -                           
SP3:                                                                                                                                -                           
SP4:                                                                          -                                                     -                 -         
SP5:              -     -     -           -     -     -     -     -     -     -                                                                                 

ExUns: 12b · 12c ^ 13
SP1:                  
SP2:                  
SP3:                  
SP4:                  
SP5:                  


ECgene alternative splicing isoforms for FAM107A

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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FAM107A expression in normal human tissues (normalized intensities)      FAM107A embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACAAAAAGGC
FAM107A Expression
About this image


FAM107A expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 10) fully expand
 
 Brain (Nervous System)    fully expand to see all 3 entries
         Mature Choroid Plexus Cells Choroid Plexus
         Cerebral Cortex
 
 Epithelial Cells
         Mature Choroid Plexus Cells Choroid Plexus
 
 Neural Ectoderm (Nervous System)
         Neural ectoderm cells
 
 Eye (Sensory Organs)
         Retina
 
 Head Mesenchyme (Muscoskeletal System)
         Frontonasal Process
FAM107A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

FAM107A Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.506357

UniProtKB/Swiss-Prot: F107A_HUMAN, O95990
Tissue specificity: Widely expressed in normal tissues. Expression is reduced or absent in a number of cancer cell
lines

    Custom PCR Arrays for FAM107A
Primer
Products:
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OriGene qSTAR qPCR primer pairs in human, mouse for FAM107A
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAM107A
QuantiTect SYBR Green Assays in human, mouse, rat FAM107A
QuantiFast Probe-based Assays in human, mouse, rat FAM107A
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM107A

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for FAM107A gene from Selected species (see all 11)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Fam107a1 , 5 family with sequence similarity 107, member A1, 5 86.34(n)1
90.97(a)1
  14 (4.80 cM)5
2687091  NM_183187.31  NP_899010.11 
 82962745 
chicken
(Gallus gallus)
Aves FAM107A1 family with sequence similarity 107, member A 68.41(n)
65.12(a)
  427591  XM_004944644.1  XP_004944701.1 
lizard
(Anolis carolinensis)
Reptilia FAM107A6
family with sequence similarity 107, member A
62(a)
1 ↔ 1
2(187034218-187125140)
African clawed frog
(Xenopus laevis)
Amphibia Xl.97002 Xenopus laevis transcribed sequence with moderate similarity more 73.2(n)    BG554253.1 
zebrafish
(Danio rerio)
Actinopterygii LOC7942561 protein FAM107A-like 58.59(n)
54.55(a)
  794256  XM_001334156.4  XP_001334192.3 


ENSEMBL Gene Tree for FAM107A (if available)
TreeFam Gene Tree for FAM107A (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for FAM107A gene
FAM107B2  
2 SIMAP similar genes for FAM107A using alignment to 4 protein entries:     F107A_HUMAN (see all proteins):
TU3A    FAM107B

FAM107A for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for FAM107A (see all 364)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
VAR_0172394
Renal cell carcinoma cell line4--see VAR_0172392 P L mis40--------
VAR_0172384
Ovarian cancer4--see VAR_0172382 L M mis40--------
rs19827581,2
C,F,H--58549647(-) TAGCCC/TACCTA 2 -- ds500134Minor allele frequency- T:0.38NS EA NA WA CSA 3193
rs19827571,2
C,F--58549666(-) TTTCTG/TCACCT 2 -- ds50018Minor allele frequency- T:0.36NA WA EA 368
rs1849229561,2
--58549757(+) GCCTGA/CAGGTA 2 -- ds50010--------
rs1153640851,2
--58549812(+) ATTTTG/TGTTGC 2 -- ds50010--------
rs1874464951,2
--58549840(+) CAACAA/GTGGTT 2 -- ds50010--------
rs1410680181,2
C--58550098(+) TTCCT-/CTTCAA 2 -- ut310--------
rs1433777311,2
--58550210(+) ATACAC/GAGTTG 2 -- ut310--------
rs1928110281,2
--58550243(+) CAAGGA/TCGTCT 2 -- ut310--------

HapMap Linkage Disequilibrium report for FAM107A (58549844 - 58613337 bp)

Structural Variations
     Database of Genomic Variants (DGV) 5 variations for FAM107A:    About this table    
Variant IDTypeSubtypePubMed ID
nsv876832CNV Loss21882294
nsv3839CNV Loss18451855
nsv876831CNV Gain21882294
nsv470605CNV Gain18288195
nsv524472CNV Gain19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing FAM107A
DNA2.0 Custom Variant and Variant Library Synthesis for FAM107A

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 608295    OMIM disorders: --

12 diseases for FAM107A:    About MalaCards
renal cell carcinoma    benign meningioma    severe combined immunodeficiency    meningioma
fibrosarcoma    choroiditis    neuroblastoma    rheumatoid arthritis
arthritis    parkinson's disease    hepatitis    breast cancer

1 disease from the University of Copenhagen DISEASES database for FAM107A:
Benign meningioma

FAM107A for disorders           About GeneDecksing

Genetic Association Database (GAD): FAM107A

Export disorders for FAM107A gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for FAM107A gene, integrated from 10 sources (see all 26):
(articles sorted by number of sources associating them with FAM107A)
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  1. Loss of expression of the DRR1 gene at chromosomal segment 3p21.1 in renal cell carcinoma. (PubMed id 10564580)1, 2, 3 Wang L....Smith D.I. (Genes Chromosomes Cancer 2000)
  2. Isolation and characterization of the novel gene, TU3A, in a commonly deleted region on 3p14.3->p14.2 in renal cell carcinoma. (PubMed id 10702698)1, 2, 3 Yamato T.... Horii A. (Cytogenet. Cell Genet. 1999)
  3. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci. (PubMed id 20453842)1, 4 Stahl E.A....Plenge R.M. (Nat. Genet. 2010)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  6. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (Genome Res. 2001)
  7. Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing. (PubMed id 11256614)1, 2 Simpson J.C.... Wiemann S. (EMBO Rep. 2000)
  8. Loss of HITS (FAM107B) expression in cancers of multiple organs: tissue microarray analysis. (PubMed id 22825356)1 Nakajima H....Motoo Y. (Int. J. Oncol. 2012)
  9. Native type IV collagen induces cell migration through a CD9 and DDR1-dependent pathway in MDA-MB-231 breast cancer cells. (PubMed id 20709424)1 Castro-Sanchez L....Salazar E.P. (Eur. J. Cell Biol. 2010)
  10. DRR1 is expressed in the developing nervous system and downregulated during neuroblastoma carcinogenesis. (PubMed id 20298674)1 Asano Y....Kadomatsu K. (Biochem. Biophys. Res. Commun. 2010)

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 11170 HGNC: 30827 AceView: TU3A Ensembl:ENSG00000168309 euGenes: HUgn11170
ECgene: FAM107A H-InvDB: FAM107A

(According to HUGE)
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(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for FAM107A Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for FAM107A Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for FAM107A gene:
Search GeneIP for patents involving FAM107A

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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