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Aliases for FAM106A Gene

Aliases for FAM106A Gene

  • Family With Sequence Similarity 106 Member A 2 3 5
  • Family With Sequence Similarity 106, Member A 2

External Ids for FAM106A Gene

Previous GeneCards Identifiers for FAM106A Gene

  • GC17M018369
  • GC17M018428
  • GC17M018429
  • GC17M018474
  • GC17M018575
  • GC17M018642
  • GC17M018677
  • GC17M018717
  • GC17M018756
  • GC17M018801

Summaries for FAM106A Gene

GeneCards Summary for FAM106A Gene

FAM106A (Family With Sequence Similarity 106 Member A) is a Protein Coding gene.

Additional gene information for FAM106A Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM106A Gene

Genomics for FAM106A Gene

Regulatory Elements for FAM106A Gene

Enhancers for FAM106A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH17H019254 0.9 dbSUPER 65 -728.1 -728112 1 ZNF493 ZFP64 ZNF121 ZNF302 KLF7 ZNF202 SP3 ZC3H11A REST ZNF623 ENSG00000264885 FOXO3B MAPK7 FAM106A SMCR8 CCDC144B ZNF286B ENSG00000262202 ENSG00000273018 ENSG00000264932
GH17H017970 1.7 FANTOM5 ENCODE dbSUPER 30 +554.8 554783 3 HDGF PKNOX1 FOXA2 ARID4B SIN3A DMAP1 ZBTB7B YY1 SLC30A9 ZNF143 SMCR8 FAM106A FOXO3B RAI1 DRG2 TOM1L2 FLII ZNF286B USP32P2 CCDC144B
GH17H018256 1.4 ENCODE dbSUPER 26.4 +267.3 267320 6 HDGF PKNOX1 ZFP64 ARID4B SIN3A DMAP1 ZNF2 ZBTB7B YY1 ZNF143 SHMT1 FAM106A LLGL1 SMCR8 MIEF2 FOXO3B ENSG00000264885 ENSG00000262202 DRG2 MYO15A
GH17H018181 1.7 FANTOM5 ENCODE dbSUPER 20.4 +341.8 341767 7 HDGF PKNOX1 ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 CBX5 ZNF143 SMCR8 MYO15A MIEF2 FAM106A NOS2P2 FOXO3B SHMT1 TBC1D3P4 YWHAEP2 ENSG00000262262
GH17H018087 1.2 ENCODE 27.3 +438.6 438630 1 MLX FEZF1 DMAP1 YY1 SLC30A9 ZNF143 ZNF548 SP3 NFYC ZC3H11A ENSG00000264885 DRG2 ZNF286B RAI1 FOXO3B LOC100419436 FAM106A SMCR5 SMCR8 ENSG00000273018
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around FAM106A on UCSC Golden Path with GeneCards custom track

Genomic Location for FAM106A Gene

Chromosome:
17
Start:
18,524,566 bp from pter
End:
18,526,846 bp from pter
Size:
2,281 bases
Orientation:
Minus strand

Genomic View for FAM106A Gene

Genes around FAM106A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM106A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM106A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM106A Gene

Proteins for FAM106A Gene

  • Protein details for FAM106A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q4KMX7-F106A_HUMAN
    Recommended name:
    Protein FAM106A
    Protein Accession:
    Q4KMX7
    Secondary Accessions:
    • Q9HAD1

    Protein attributes for FAM106A Gene

    Size:
    169 amino acids
    Molecular mass:
    18795 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FAM106A Gene

Post-translational modifications for FAM106A Gene

No Post-translational modifications

Other Protein References for FAM106A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM106A Gene

Domains & Families for FAM106A Gene

Gene Families for FAM106A Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for FAM106A Gene

ProtoNet:

Suggested Antigen Peptide Sequences for FAM106A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q4KMX7

UniProtKB/Swiss-Prot:

F106A_HUMAN :
  • Belongs to the FAM106 family.
Family:
  • Belongs to the FAM106 family.
genes like me logo Genes that share domains with FAM106A: view

Function for FAM106A Gene

Phenotypes From GWAS Catalog for FAM106A Gene

genes like me logo Genes that share phenotypes with FAM106A: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for FAM106A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FAM106A Gene

Localization for FAM106A Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for FAM106A Gene

Pathways & Interactions for FAM106A Gene

SuperPathways for FAM106A Gene

No Data Available

Interacting Proteins for FAM106A Gene

Gene Ontology (GO) - Biological Process for FAM106A Gene

None

No data available for Pathways by source and SIGNOR curated interactions for FAM106A Gene

Drugs & Compounds for FAM106A Gene

No Compound Related Data Available

Transcripts for FAM106A Gene

mRNA/cDNA for FAM106A Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(10) Selected AceView cDNA sequences:
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FAM106A Gene

Family with sequence similarity 106, member A:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for FAM106A
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for FAM106A Gene

No ASD Table

Relevant External Links for FAM106A Gene

GeneLoc Exon Structure for
FAM106A
ECgene alternative splicing isoforms for
FAM106A

Expression for FAM106A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for FAM106A Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM106A Gene:

FAM106A

SOURCE GeneReport for Unigene cluster for FAM106A Gene:

Hs.674403
genes like me logo Genes that share expression patterns with FAM106A: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for FAM106A Gene

Orthologs for FAM106A Gene

Evolution for FAM106A Gene

ENSEMBL:
Gene Tree for FAM106A (if available)
TreeFam:
Gene Tree for FAM106A (if available)

No data available for Orthologs for FAM106A Gene

Paralogs for FAM106A Gene

(2) SIMAP similar genes for FAM106A Gene using alignment to 1 proteins:

Pseudogenes.org Pseudogenes for FAM106A Gene

genes like me logo Genes that share paralogs with FAM106A: view

No data available for Paralogs for FAM106A Gene

Variants for FAM106A Gene

Sequence variations from dbSNP and Humsavar for FAM106A Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type
rs1002600646 -- 18,526,896(+) AACAT(G/T)TTTCT upstream-variant-2KB
rs1002647908 -- 18,527,663(+) GCAAG(G/T)GCTTC upstream-variant-2KB
rs1004460114 -- 18,524,527(+) AGTGC(-/CA)GTCTG downstream-variant-500B
rs1010943053 -- 18,526,943(+) ATTTA(-/TTTAT)TTTAT upstream-variant-2KB
rs1015003274 -- 18,527,977(+) TCTGA(C/G)ACCTG upstream-variant-2KB

Structural Variations from Database of Genomic Variants (DGV) for FAM106A Gene

Variant ID Type Subtype PubMed ID
dgv27e213 CNV loss 24956385
dgv3110n100 CNV gain 25217958
dgv3111n100 CNV gain 25217958
dgv3112n100 CNV gain+loss 25217958
dgv3113n100 CNV loss 25217958
dgv3114n100 CNV gain+loss 25217958
dgv3115n100 CNV gain 25217958
dgv5489n54 CNV loss 21841781
dgv55e203 CNV gain+loss 21179565
esv2670394 CNV deletion 23128226
esv2758677 CNV gain+loss 17122850
esv3640153 CNV loss 21293372
nsv1121932 CNV deletion 24896259
nsv1144794 CNV deletion 24896259
nsv1160460 OTHER complex 26073780
nsv1160461 CNV deletion 26073780
nsv428333 CNV gain 18775914
nsv442738 CNV gain+loss 18776908
nsv469661 CNV gain 16826518
nsv511052 OTHER complex 20534489
nsv511593 CNV loss 21212237
nsv827913 CNV gain 20364138
nsv833388 CNV loss 17160897
nsv9504 CNV gain+loss 18304495
nsv953840 CNV deletion 24416366
nsv962275 CNV duplication 23825009

Variation tolerance for FAM106A Gene

Gene Damage Index Score: 0.06; 1.45% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM106A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
FAM106A

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM106A Gene

Disorders for FAM106A Gene

Relevant External Links for FAM106A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
FAM106A

No disorders were found for FAM106A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM106A Gene

Publications for FAM106A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 2 3 4 60
  2. DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage. (PMID: 16625196) Zody MC … Nusbaum C (Nature 2006) 4 60
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 60
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 60
  5. Structure and evolution of the Smith-Magenis syndrome repeat gene clusters, SMS-REPs. (PMID: 11997339) Park SS … Lupski JR (Genome research 2002) 3 60

Products for FAM106A Gene

Sources for FAM106A Gene

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