V3 here soon-try beta now
Gene Search (GeneCards Home) | GeneCards Guide | User Feedback | Terms of Use | Notice about third-party sites
 

FAM104B Gene

protein-coding   GIFtS: 35

GC0XM055186
family with sequence similarity 104, member B
(Previous name: chromosome X open reading frame 44 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: CXorf44)
Services    

Aliases &
Descriptions
for FAM104B

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc , and/or 7Ensembl, 8miRBase)
About This Section
Aliases
CXorf44 2, 3
FLJ20434 1, 2
Descriptions
chromosome X open reading frame 44 1
family with sequence similarity 104, member B 2
hypothetical protein LOC90736 2
External Ids
HGNC: 250851
Entrez Gene: 907362
UniProtKB: Q5XKR93
Ensembl: ENSG000001825187
Search outside databases for aliases for FAM104B gene

Summaries
for FAM104B

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

   --

Genomic Location
for FAM104B

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

 Genomic View:
UCSC Golden Path with GeneCards custom track

 Transcription factor binding sites upstream to the FAM104B gene  

Entrez Gene cytogenetic band: Xp11.21   Ensembl cytogenetic band:  Xp11.21   HGNC cytogenetic band: Xp11.22

FAM104B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XM055186:     (about GC identifiers)

Start:
 55,186,260 bp from pter
End:
 55,204,468 bp from pter
Size:
 18,209 bases
Orientation:
 minus strand
RefSeq DNA sequence:
NC_000023.9  NT_011630.14  

Proteins
for FAM104B

(According to 1UniProtKB, and/or Ensembl, Phosphorylation sites according to 2Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

 UniProtKB/Swiss-Prot: F104B_HUMAN, Q5XKR9 (See protein sequence)
Recommended Name: Protein FAM104B  
Size: 115 amino acids; 13109 Da
Secondary accessions: A6NEH1 Q8WVU5 Q9BRA1
Alternative splicing: 3 isoforms:  Q5XKR9-1   Q5XKR9-2   Q5XKR9-3   

REFSEQ proteins: NP_612371.1  

ENSEMBL proteins: 
ENSP00000333394 ENSP00000364101 


Human Recombinant Proteins 
Browse Drug Discovery Central at Invitrogen for human recombinant proteins
Browse Purified and Recombinant Proteins at Millipore
Browse Human Recombinant Proteins at Sigma-Aldrich  
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse Abcam for Recombinant Proteins
Browse Abnova for Human Recombinant Proteins
                Browse Origene for full length recombinant human proteins expressed in human HEK293 cells 


Antibodies for FAM104B: 
Browse Antibodies Central at Invitrogen
Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse Antibodies at Sigma-Aldrich
Browse R&D Systems for Antibodies
Search for antibodies at Abcam and the World's Antibody Gateway (free search engine of over 150 antibody companies)
Browse Abnova for Monoclonal and Polyclonal Antibodies
Search Novus for antibodies for FAM104B

Assays for FAM104B: 
Browse Invitrogen for biochemical assays
Browse Kits and Assays available from Millipore
Browse R&D Systems for biochemical assays
Browse biochemical assays available from Enzo Life Sciences

Protein Domains/
Families
for FAM104B

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ProtoNet protein and cluster: Q5XKR9

UniProtKB/Swiss-Prot: F104B_HUMAN, Q5XKR9
Similarity: Belongs to the FAM104 family

Gene Function
for FAM104B

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (FAM104B)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138362

              Applied Biosystems Silencer® siRNAs for FAM104B

              Sigma-Aldrich siRNA for FAM104B  
                     Sigma-Aldrich shRNA for FAM104B  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Clones:Invitrogen Clones for FAM104B
Browse Clones for the Expression of Recombinant Proteins Available from Millipore
              OriGene GFP tagged cDNA clone in CMV expression vector: NM_138362
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_138362
                                 untagged cDNA clone in CMV expression vector: NM_138362 

Primers: Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
              OriGene genome-wide validated SYBR primer pairs: NM_138362

Pathways & Interactions
for FAM104B

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to 1UniProtKB, 2MINT, and/or 3STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section


  --

Drugs & Compounds
for FAM104B

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences
Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for FAM104B

Transcripts
for FAM104B

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section
Inhib.
RNA:		Invitrogen RNAi Products for gene knock-down (FAM104B)
Browse for Gene Knock-down Tools from Millipore
Browse Abnova for Chimera RNAi Products
              OriGene 29mer shRNA kit in GFP-retroviral vector: NM_138362

              Sigma-Aldrich siRNA for FAM104B  
                     Sigma-Aldrich shRNA for FAM104B  
                     Explore Sigma-Aldrich super-pooled esiRNAs  

Applied Biosystems Silencer® siRNAs: 

NM_138362  

REFSEQ mRNAs for FAM104B gene: 

NM_138362.2   

Applied Biosystems TaqMan ® Gene Expression Assays: 

NM_138362  

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_138362
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_138362
                                 untagged cDNA clone in CMV expression vector: NM_138362 

Additional cDNA sequence: 

AK000441.1 AK299935.1 AK311333.1 AK311699.1 BC000919.2 BC006406.2 BC017571.1 CR591055.1 

8 DOTS entries:

DT.440827  DT.40111465  DT.99957386  DT.100780911  DT.209575  DT.121288047  DT.95369321  DT.92421565 

24/128 AceView cDNA sequences (see all 128 ):

BX100076 AW157241 BE646164 BE908600 H90684 BQ215751 BI850888 BF476227 
AW163244 AA563794 AI499798 BC017571 BQ772137 BM014954 N31946 AI369864 
AI199617 BC000919 BI753532 AI742475 BC006406 CR591055 AW206271 AI190785 

highest scoring ESTs for FAM104B:

AK000441 BC000919 BC006406 BC017571 BF243236 CK004182 AA508171 AA826443 AI084290 AI190785 

Unigene Cluster for FAM104B:

Family with sequence similarity 104, member B
Hs.415414  [show with all ESTs]
Unigene Representative Sequence: AK311699


GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for FAM104B (see all 8 )

ExUns: 1a · 1b ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d · 4e · 4f ^ 5a · 5b
SP1:              -     -     -                 -     -     -     -     -               
SP2:              -     -     -                 -     -     -     -     -               
SP3:              -     -     -                 -     -     -     -     -               
SP4:              -     -     -                                                         
SP5:              -     -     -                                                         

About this scheme

ECgene alternative splicing isoforms for FAM104B

2 Ensembl transcripts including schematic representations:
ENST00000332132  ENST00000358460  

Expression
for FAM104B

(Experimental results according to 1GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to 2GeneAnnot , 3GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FAM104B expression in normal and diseased human tissues

 Applied Biosystems TaqMan ® Gene Expression Assays for FAM104B

1 / 2 / 3

6 probe-sets matching FAM104B gene


Affymetrix
probe-set		 Array  GeneAnnot data GeneNote data GeneTide data
# genes Sensitivity Specificity Correlation Length Gb_Accession Consensus Uniqueness Score Rank
65691_at2, 3 U95-C 2 1.00 0.88 0.56 0.98 N31946 0.60 1.00 0.82 1

50049_f_at2, 3 U95-B 3 0.94 0.96 0.42 1.03 AA045236 0.40 1.00 0.76 1

232990_at2, 3 U133-B 1 1.00 1.00 -- -- BG285399 0.60 1.00 0.82 1

227869_at2, 3 U133-B 1 0.64 1.00 -- -- BG500573 0.20 1.00 0.72 1

232990_at2 U133Plus2 1 1.00 1.00 -- -- -- -- -- -- --

227869_at2 U133Plus2 1 0.64 1.00 -- -- -- -- -- -- --
GeneDecks  FAM104B for binary patterns associated with the probe-sets selected above  
About GeneDecksing
About this table    
Data from (Publications) and GNF BioGPS
    About these images
About these images

CGAP SAGE TAG: ATGAATTAGG

SOURCE GeneReport for Unigene cluster: Hs.415414

Orthologs
for FAM104B

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD and/or 5MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

 ENSEMBL Gene Tree for FAM104B

Paralogs
for FAM104B

(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section

Paralogs for FAM104B gene
FAM104A2  

SNPs/Variants
for FAM104B

(According to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section


10/88 NCBI SNPs in FAM104B are shown (see all 88 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay)  (see all 29)
ABGenomic DataTranscription DataAllele Frequencies
SNP IDValidChr X posSequenceRecsAA
Chg		TypeMoreRecsAllele
freq		PopTotal
sample		More
------------
rs78897821,2
A,F,H55186207(+) TtgtaT/Acgcca 1 -- ng514Minor allele frequency- A:0.01EU EA WA 416
--
rs48263711,2
A,C55205815(+) tgctcC/Tccacc 1 -- ng310--------
--
rs128400161,2
H55204672(+) ATCCTC/ACTCGG 1 -- ng314Minor allele frequency- A:0.00EU EA WA 420
rs10470421,2
F55189370(-) AACCCA/GATGCA 1 D/N mis1 ese31Minor allele frequency- G:0.47MN 184
rs50030011,2
H55202381(+) TTCTTC/ATTTTC 1 I/R mis1 trp34Minor allele frequency- A:0.00EU EA WA 418
--
rs10470341,2
F55189433(-) GCCGCC/ATTAAT 1 L/I mis11Minor allele frequency- A:0.31MN 184
rs10470371,2
F55189412(-) GAGCAA/GGTGGA 1 S/G mis11Minor allele frequency- G:0.43MN 184
--
rs50186871,2
H55189384(+) TAACAA/GTCTGG 1 I/T mis14Minor allele frequency- G:0.00EU EA WA 376
rs18741101,2
A,C,F,H55200825(+) CTCCTG/AGTTCT 1 -- int17Minor allele frequency- A:0.36EU EA WA NA 554
rs18741111,2
A,C,F,H55200976(+) ATAATA/TTTCCA 1 -- int111Minor allele frequency- N:0.00NA EA EU WA 879
About this table

HapMap Linkage Disequilibrium images for FAM104B (up to first 250kb)

Disorders & Mutations
for FAM104B

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

   --

Medical News
for FAM104B

(Possibly Related Articles in Doctor's Guide)
About This Section

   --

Publications
for FAM104B

(in PubMed. Associations of this gene to articles via 1Novoseek, 2HGNC, 3Entrez Gene, 4UniProtKB/Swiss-Prot, 5UniProtKB/TrEMBL, 6GAD, and/or 7PharmGKB)
About This Section

3 PubMed articles for FAM104B gene:

Search for FAM104B

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

 ANDOR
Aliases
Free Text  
  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

Genome Databases showing FAM104B

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section
Entrez Gene: 90736 HGNC: 25085 AceView: CXorf44 Ensembl:ENSG00000182518 euGenes: HUgn90736
ECgene: FAM104B H-InvDB: FAM104B

Other Databases showing FAM104B

(According to HUGE)
About This Section

   --

Specialized Databases showing FAM104B

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

   --

Licensable Technologies
for FAM104B

(Available from WIS Yeda, Salk, Tufts)
About This Section

  --

Services
for FAM104B

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section



Products for FAM104B:
 TaqMan ® Gene Expression Assays
 TaqMan ® Genotyping Assays
  Free SNP selection tool



  Invitrogen iPath Pathways  Invitrogen BLOCK-iT™ RNAi
  Invitrogen Antibodies  Invitrogen Assays
  Invitrogen Clones  Invitrogen Q-PCR Products
  Invitrogen Human Recombinant Kinases  Invitrogen Custom Antibody and Peptide Service
  Invitrogen Proteins / Assays / Screening Services  Search Invitrogen catalog for FAM104B-related products

 Millipore Custom Antibody & Bulk Services
 Millipore Preclinical / Clinical Development Services
 Millipore Immunoassay Services
 Millipore Target Screening & Profiling Services


 Predesigned and custom siRNAs for FAM104B Browse antibodies at Sigma-Aldrich
 Explore super-pooled esiRNAs Browse proteins at Sigma-Aldrich
 Lentivirus-delivered shRNAs for FAM104B Browse small molecules at Sigma-Aldrich
 "Your Favorite Gene" Pathwaysfeedback


  
 Antibodies   Primer Pairs  
 Cell Culture Products   ELISAs  
 Flow Cytometry Kits   Protease Activity Assays & Reagents  
 Cell Selection/Detection Kits & Reagents   ELISA/Assay Development Kits & Reagents  
 Multiplex/Array Assay Kits & Reagents   ELISpot Kits & Development Modules  
 Recombinant & Natural Proteins  

 Search for Recombinant Proteins
 Search for Antibodies
 Search for Chimera RNAi
 Custom Service for Mouse Mab
 Custom Service for Rabbit Pab from Full-length Protein
  
 Search for Antibodies & Assays

 Search for Recombinant Proteins
 Search for Antibodies
 Search OriGene for FAM104B
 Search Tocris compounds for FAM104B




 Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies
 Search Novus for antibodies for FAM104B

GeneCards Homepage    -    Last full update: 1 Jul 2009        Incremental update: 13 Oct 2009

Random Gene From GIFtS : about GIFtS

Gene Index:   3   5   A   B   C   D   E   F   G   H   I   J   K   L   M   N   O   P   Q   R   S   T   U   V   W   X   Y   Z

Developed at the Crown Human Genome Center & Weizmann Institute of Science



The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
FAM104B Gene at Home site.
Version 2.41.1
server5.xennexinc.com