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Aliases for FAM104A Gene

Aliases for FAM104A Gene

  • Family With Sequence Similarity 104, Member A 2 3

External Ids for FAM104A Gene

Summaries for FAM104A Gene

GeneCards Summary for FAM104A Gene

FAM104A (Family With Sequence Similarity 104, Member A) is a Protein Coding gene. An important paralog of this gene is FAM104B.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM104A Gene

Genomics for FAM104A Gene

Genomic Location for FAM104A Gene

Start:
73,207,353 bp from pter
End:
73,236,753 bp from pter
Size:
29,401 bases
Orientation:
Minus strand

Genomic View for FAM104A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM104A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM104A Gene

Regulatory Elements for FAM104A Gene

Proteins for FAM104A Gene

  • Protein details for FAM104A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q969W3-F104A_HUMAN
    Recommended name:
    Protein FAM104A
    Protein Accession:
    Q969W3
    Secondary Accessions:
    • B4E339

    Protein attributes for FAM104A Gene

    Size:
    186 amino acids
    Molecular mass:
    19484 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAH11054.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH25238.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAB55292.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=BAC11183.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM104A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM104A Gene

Proteomics data for FAM104A Gene at MOPED

Post-translational modifications for FAM104A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for FAM104A Gene

Domains for FAM104A Gene

Protein Domains for FAM104A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F104A_HUMAN
Family:
  • Belongs to the FAM104 family.:
    • Q969W3
genes like me logo Genes that share domains with FAM104A: view

No data available for Gene Families for FAM104A Gene

Function for FAM104A Gene

Gene Ontology (GO) - Molecular Function for FAM104A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM104A: view
genes like me logo Genes that share phenotypes with FAM104A: view

miRNA for FAM104A Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM104A Gene

Localization for FAM104A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM104A Gene COMPARTMENTS Subcellular localization image for FAM104A gene
Compartment Confidence
nucleus 3
cytosol 2
extracellular 1

No data available for Gene Ontology (GO) - Cellular Components for FAM104A Gene

Pathways for FAM104A Gene

SuperPathways for FAM104A Gene

No Data Available

Interacting Proteins for FAM104A Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000384832%0d%0a9606.ENSP00000351777%0d%0a
Selected Interacting proteins: ENSP00000384832 Q969W3-F104A_HUMAN for FAM104A Gene via STRING UniProtKB

Gene Ontology (GO) - Biological Process for FAM104A Gene

None

No data available for Pathways by source for FAM104A Gene

Transcripts for FAM104A Gene

Unigene Clusters for FAM104A Gene

Family with sequence similarity 104, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM104A Gene

No ASD Table

Relevant External Links for FAM104A Gene

GeneLoc Exon Structure for
FAM104A
ECgene alternative splicing isoforms for
FAM104A

Expression for FAM104A Gene

mRNA expression in normal human tissues for FAM104A Gene

mRNA differential expression in normal tissues according to GTEx for FAM104A Gene

This gene is overexpressed in Testis (13.0).

Integrated Proteomics: protein expression from ProteomicsDB and MOPED for FAM104A Gene

SOURCE GeneReport for Unigene cluster for FAM104A Gene Hs.741276

genes like me logo Genes that share expressions with FAM104A: view

Orthologs for FAM104A Gene

This gene was present in the common ancestor of chordates.

Orthologs for FAM104A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM104A 37
  • 100 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM104A 36
  • 85.45 (n)
  • 84.53 (a)
MGC128049 37
  • 85 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM104A 36
  • 83.05 (n)
  • 80.34 (a)
FAM104A 37
  • 88 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam104a 36
  • 76.99 (n)
  • 72.28 (a)
Fam104a 16
Fam104a 37
  • 78 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 37
  • 82 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 37
  • 80 (a)
OneToMany
rat
(Rattus norvegicus)
Mammalia Fam104a 36
  • 82.51 (n)
  • 80.33 (a)
chicken
(Gallus gallus)
Aves FAM104A 36
  • 72.06 (n)
  • 69.52 (a)
FAM104A 37
  • 67 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia -- 37
  • 66 (a)
OneToMany
Species with no ortholog for FAM104A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FAM104A Gene

ENSEMBL:
Gene Tree for FAM104A (if available)
TreeFam:
Gene Tree for FAM104A (if available)

Paralogs for FAM104A Gene

Paralogs for FAM104A Gene

Selected SIMAP similar genes for FAM104A Gene using alignment to 5 proteins:

genes like me logo Genes that share paralogs with FAM104A: view

Variants for FAM104A Gene

Sequence variations from dbSNP and Humsavar for FAM104A Gene

SNP ID Clin Chr 17 pos Sequence Context AA Info Type MAF
rs8387 -- 73,209,715(-) ATCAA(C/T)AGCCC synonymous-codon, reference, missense
rs14098 -- 73,209,682(-) GGCAG(C/T)TTGAG reference, synonymous-codon, missense
rs15072 -- 73,209,142(+) TTGAA(A/T)AAAAA utr-variant-3-prime
rs935714 -- 73,212,014(+) caatc(A/G)gaatg intron-variant
rs1080345 -- 73,223,797(+) caaca(C/T)agcaa intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM104A Gene

Variant ID Type Subtype PubMed ID
nsv833534 CNV Loss 17160897
esv2186746 CNV Deletion 18987734
esv2667654 CNV Deletion 23128226
esv2562139 CNV Deletion 19546169

Relevant External Links for FAM104A Gene

HapMap Linkage Disequilibrium report
FAM104A

Disorders for FAM104A Gene

No disorders were found for FAM104A Gene.

No data available for UniProtKB/Swiss-Prot for FAM104A Gene

Publications for FAM104A Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  3. Mapping and characterization of novel (CAG)n repeat cDNAs from adult human brain derived by the oligo capture method. (PMID: 9417904) Reddy P.H. … Tagle D.A. (Genomics 1997) 3 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for FAM104A Gene

Sources for FAM104A Gene

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