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Aliases for FAM102B Gene

Aliases for FAM102B Gene

  • Family With Sequence Similarity 102, Member B 2 3
  • Sym-3 Homolog B (C. Elegans) 2
  • Protein FAM102B 3
  • Sym-3 Homolog B 3
  • SYM-3B 3

External Ids for FAM102B Gene

Previous GeneCards Identifiers for FAM102B Gene

  • GC01P108703
  • GC01P108904
  • GC01P109102
  • GC01P106996

Summaries for FAM102B Gene

GeneCards Summary for FAM102B Gene

FAM102B (Family With Sequence Similarity 102, Member B) is a Protein Coding gene. An important paralog of this gene is FAM102A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM102B Gene

Genomics for FAM102B Gene

Regulatory Elements for FAM102B Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for FAM102B Gene

Start:
108,560,089 bp from pter
End:
108,644,900 bp from pter
Size:
84,812 bases
Orientation:
Plus strand

Genomic View for FAM102B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM102B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM102B Gene

Proteins for FAM102B Gene

  • Protein details for FAM102B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T8I3-F102B_HUMAN
    Recommended name:
    Protein FAM102B
    Protein Accession:
    Q5T8I3
    Secondary Accessions:
    • A1L1A1
    • B0QZ46
    • B0QZ47
    • Q68DH7

    Protein attributes for FAM102B Gene

    Size:
    360 amino acids
    Molecular mass:
    39308 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=AAI27899.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI40864.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI40866.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI50531.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM102B Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM102B Gene

Proteomics data for FAM102B Gene at MOPED

Post-translational modifications for FAM102B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM102B Gene

ENSEMBL proteins:
REFSEQ proteins:

Antibody Products

No data available for DME Specific Peptides for FAM102B Gene

Domains for FAM102B Gene

Protein Domains for FAM102B Gene

InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for FAM102B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q5T8I3

UniProtKB/Swiss-Prot:

F102B_HUMAN :
  • Q5T8I3
Family:
  • Belongs to the FAM102 family.
genes like me logo Genes that share domains with FAM102B: view

No data available for Gene Families for FAM102B Gene

Function for FAM102B Gene

Animal Model Products

CRISPR Products

miRNA for FAM102B Gene

miRTarBase miRNAs that target FAM102B

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM102B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM102B Gene

Localization for FAM102B Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM102B Gene COMPARTMENTS Subcellular localization image for FAM102B gene
Compartment Confidence
nucleus 2
cytosol 1
extracellular 1
plasma membrane 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM102B Gene

Pathways for FAM102B Gene

SuperPathways for FAM102B Gene

No Data Available

Interacting Proteins for FAM102B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
http://string-db.org/version_10/api/image/networkList?limit=0&targetmode=proteins&caller_identity=gene_cards&network_flavor=evidence&identifiers=9606.ENSP00000359052%0d%0a9606.ENSP00000385269%0d%0a
Selected Interacting proteins: ENSP00000359052 for FAM102B Gene via STRING

Symbol External ID(s) Details
ELAVL1

Gene Ontology (GO) - Biological Process for FAM102B Gene

None

No data available for Pathways by source for FAM102B Gene

Transcripts for FAM102B Gene

mRNA/cDNA for FAM102B Gene

Unigene Clusters for FAM102B Gene

Family with sequence similarity 102, member B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for FAM102B

Primer Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM102B Gene

No ASD Table

Relevant External Links for FAM102B Gene

GeneLoc Exon Structure for
FAM102B
ECgene alternative splicing isoforms for
FAM102B

Expression for FAM102B Gene

mRNA expression in normal human tissues for FAM102B Gene

Protein differential expression in normal tissues for FAM102B Gene

This gene is overexpressed in Peripheral blood mononuclear cells (42.1), Pancreas (14.0), and Fetal heart (12.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM102B Gene

SOURCE GeneReport for Unigene cluster for FAM102B Gene Hs.200230

genes like me logo Genes that share expressions with FAM102B: view

Expression partners for FAM102B Gene

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM102B Gene

Orthologs for FAM102B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM102B Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia FAM102B 35
  • 92.95 (n)
  • 94.29 (a)
FAM102B 36
  • 86 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM102B 35
  • 91.93 (n)
  • 95.1 (a)
FAM102B 36
  • 94 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam102b 35
  • 89.63 (n)
  • 95.28 (a)
Fam102b 16
Fam102b 36
  • 93 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia FAM102B 35
  • 99.81 (n)
  • 100 (a)
FAM102B 36
  • 100 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam102b 35
  • 88.33 (n)
  • 94.44 (a)
oppossum
(Monodelphis domestica)
Mammalia -- 36
  • 90 (a)
OneToMany
-- 36
  • 88 (a)
OneToMany
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 80 (a)
OneToMany
-- 36
  • 96 (a)
OneToMany
chicken
(Gallus gallus)
Aves FAM102B 35
  • 81.08 (n)
  • 85.01 (a)
-- 36
  • 64 (a)
OneToMany
-- 36
  • 76 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia FAM102B 36
  • 82 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam102b 35
  • 73.63 (n)
  • 81.89 (a)
zebrafish
(Danio rerio)
Actinopterygii fam102bb 35
  • 70.29 (n)
  • 77.44 (a)
fam102ba 36
  • 69 (a)
OneToMany
fam102bb 36
  • 75 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG8671 36
  • 13 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea sym-3 36
  • 25 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 33 (a)
ManyToMany
-- 36
  • 32 (a)
ManyToMany
Species with no ortholog for FAM102B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM102B Gene

ENSEMBL:
Gene Tree for FAM102B (if available)
TreeFam:
Gene Tree for FAM102B (if available)

Paralogs for FAM102B Gene

Paralogs for FAM102B Gene

Selected SIMAP similar genes for FAM102B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM102B: view

Variants for FAM102B Gene

Sequence variations from dbSNP and Humsavar for FAM102B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type MAF
rs11529 -- 108,639,159(-) ATTCT(A/C)CAAGT utr-variant-3-prime
rs904330 -- 108,612,522(+) TTTGA(A/G)CATTC intron-variant
rs904331 -- 108,634,800(+) TTTAG(A/C)ATGAA intron-variant
rs924303 -- 108,569,670(+) tatga(C/T)tAAGC intron-variant
rs931660 -- 108,615,629(+) AAAAG(A/G)AAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM102B Gene

Variant ID Type Subtype PubMed ID
esv1009643 CNV Deletion 20482838

Relevant External Links for FAM102B Gene

HapMap Linkage Disequilibrium report
FAM102B

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM102B Gene

Disorders for FAM102B Gene

Relevant External Links for FAM102B

Genetic Association Database (GAD)
FAM102B

No disorders were found for FAM102B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for FAM102B Gene

Publications for FAM102B Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4
  2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4
  3. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3
  4. Genome-wide association with bone mass and geometry in the Framingham Heart Study. (PMID: 17903296) Kiel D.P. … Karasik D. (BMC Med. Genet. 2007) 48
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FAM102B Gene

Sources for FAM102B Gene

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