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Aliases for FAM102B Gene

Aliases for FAM102B Gene

  • Family With Sequence Similarity 102 Member B 2 3 5
  • Family With Sequence Similarity 102, Member B 2
  • Sym-3 Homolog B (C. Elegans) 2
  • Protein FAM102B 3
  • Sym-3 Homolog B 3
  • SYM-3B 3

External Ids for FAM102B Gene

Previous GeneCards Identifiers for FAM102B Gene

  • GC01P108703
  • GC01P108904
  • GC01P109102
  • GC01P106996

Summaries for FAM102B Gene

GeneCards Summary for FAM102B Gene

FAM102B (Family With Sequence Similarity 102 Member B) is a Protein Coding gene. An important paralog of this gene is FAM102A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM102B Gene

Genomics for FAM102B Gene

Regulatory Elements for FAM102B Gene

Enhancers for FAM102B Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around FAM102B on UCSC Golden Path with GeneCards custom track

Promoters for FAM102B Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

Genomic Location for FAM102B Gene

108,560,089 bp from pter
108,644,900 bp from pter
84,812 bases
Plus strand

Genomic View for FAM102B Gene

Genes around FAM102B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FAM102B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FAM102B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM102B Gene

Proteins for FAM102B Gene

  • Protein details for FAM102B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Protein FAM102B
    Protein Accession:
    Secondary Accessions:
    • A1L1A1
    • B0QZ46
    • B0QZ47
    • Q68DH7

    Protein attributes for FAM102B Gene

    360 amino acids
    Molecular mass:
    39308 Da
    Quaternary structure:
    No Data Available
    • Sequence=AAI27899.2; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI40864.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI40866.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=AAI50531.1; Type=Erroneous initiation; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM102B Gene


neXtProt entry for FAM102B Gene

Post-translational modifications for FAM102B Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM102B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM102B Gene

Domains & Families for FAM102B Gene

Protein Domains for FAM102B Gene


Suggested Antigen Peptide Sequences for FAM102B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 NT-C2 domain.
  • Belongs to the FAM102 family.
  • Contains 1 NT-C2 domain.
  • Belongs to the FAM102 family.
genes like me logo Genes that share domains with FAM102B: view

No data available for Gene Families for FAM102B Gene

Function for FAM102B Gene

Phenotypes for FAM102B Gene

GenomeRNAi human phenotypes for FAM102B:
genes like me logo Genes that share phenotypes with FAM102B: view

Animal Model Products

CRISPR Products

miRNA for FAM102B Gene

miRTarBase miRNAs that target FAM102B

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for FAM102B Gene

Localization for FAM102B Gene

Subcellular locations from

Jensen Localization Image for FAM102B Gene COMPARTMENTS Subcellular localization image for FAM102B gene
Compartment Confidence
cytosol 3
nucleus 3
plasma membrane 2
extracellular 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FAM102B Gene

Pathways & Interactions for FAM102B Gene

SuperPathways for FAM102B Gene

No Data Available

Interacting Proteins for FAM102B Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000359052 Q5T8I3-F102B_HUMAN for FAM102B Gene via STRING IID

Gene Ontology (GO) - Biological Process for FAM102B Gene


No data available for Pathways by source and SIGNOR curated interactions for FAM102B Gene

Drugs & Compounds for FAM102B Gene

No Compound Related Data Available

Transcripts for FAM102B Gene

mRNA/cDNA for FAM102B Gene

Unigene Clusters for FAM102B Gene

Family with sequence similarity 102, member B:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for FAM102B Gene

No ASD Table

Relevant External Links for FAM102B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FAM102B Gene

mRNA expression in normal human tissues for FAM102B Gene

Protein differential expression in normal tissues from HIPED for FAM102B Gene

This gene is overexpressed in Peripheral blood mononuclear cells (42.1), Pancreas (14.0), and Fetal heart (12.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for FAM102B Gene

Protein tissue co-expression partners for FAM102B Gene

NURSA nuclear receptor signaling pathways regulating expression of FAM102B Gene:


SOURCE GeneReport for Unigene cluster for FAM102B Gene:

genes like me logo Genes that share expression patterns with FAM102B: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for FAM102B Gene

Orthologs for FAM102B Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM102B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FAM102B 34
  • 92.95 (n)
  • 94.29 (a)
FAM102B 35
  • 86 (a)
(Canis familiaris)
Mammalia FAM102B 34
  • 91.93 (n)
  • 95.1 (a)
FAM102B 35
  • 94 (a)
(Mus musculus)
Mammalia Fam102b 34
  • 89.63 (n)
  • 95.28 (a)
Fam102b 16
Fam102b 35
  • 93 (a)
(Pan troglodytes)
Mammalia FAM102B 34
  • 99.81 (n)
  • 100 (a)
FAM102B 35
  • 100 (a)
(Rattus norvegicus)
Mammalia Fam102b 34
  • 88.33 (n)
  • 94.44 (a)
(Monodelphis domestica)
Mammalia -- 35
  • 90 (a)
-- 35
  • 88 (a)
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 80 (a)
-- 35
  • 96 (a)
(Gallus gallus)
Aves FAM102B 34
  • 81.08 (n)
  • 85.01 (a)
-- 35
  • 64 (a)
-- 35
  • 76 (a)
(Anolis carolinensis)
Reptilia FAM102B 35
  • 82 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia fam102b 34
  • 73.63 (n)
  • 81.89 (a)
(Danio rerio)
Actinopterygii fam102bb 34
  • 70.29 (n)
  • 77.44 (a)
fam102ba 35
  • 69 (a)
fam102bb 35
  • 75 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG8671 35
  • 13 (a)
(Caenorhabditis elegans)
Secernentea sym-3 35
  • 25 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 35
  • 33 (a)
-- 35
  • 32 (a)
Species where no ortholog for FAM102B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM102B Gene

Gene Tree for FAM102B (if available)
Gene Tree for FAM102B (if available)

Paralogs for FAM102B Gene

Paralogs for FAM102B Gene

(1) SIMAP similar genes for FAM102B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM102B: view

Variants for FAM102B Gene

Sequence variations from dbSNP and Humsavar for FAM102B Gene

SNP ID Clin Chr 01 pos Sequence Context AA Info Type
rs11529 -- 108,639,159(-) ATTCT(A/C)CAAGT utr-variant-3-prime
rs904330 -- 108,612,522(+) TTTGA(A/G)CATTC intron-variant
rs904331 -- 108,634,800(+) TTTAG(A/C)ATGAA intron-variant
rs924303 -- 108,569,670(+) tatga(C/T)tAAGC intron-variant
rs931660 -- 108,615,629(+) AAAAG(A/G)AAAGA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FAM102B Gene

Variant ID Type Subtype PubMed ID
esv1009643 CNV deletion 20482838
nsv1126201 CNV deletion 24896259

Variation tolerance for FAM102B Gene

Residual Variation Intolerance Score: 54.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.60; 12.86% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for FAM102B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for FAM102B Gene

Disorders for FAM102B Gene

Relevant External Links for FAM102B

Genetic Association Database (GAD)
Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FAM102B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FAM102B Gene

Publications for FAM102B Gene

  1. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory S.G. … Bentley D.R. (Nature 2006) 3 4 65
  2. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PMID: 17081983) Olsen J.V. … Mann M. (Cell 2006) 3 4 65
  3. A human interactome in three quantitative dimensions organized by stoichiometries and abundances. (PMID: 26496610) Hein M.Y. … Mann M. (Cell 2015) 3 65
  4. Toward a comprehensive characterization of a human cancer cell phosphoproteome. (PMID: 23186163) Zhou H. … Mohammed S. (J. Proteome Res. 2013) 4 65
  5. Ubiquitin-mediated proteolysis of HuR by heat shock. (PMID: 19322201) Abdelmohsen K. … Gorospe M. (EMBO J. 2009) 3 65

Products for FAM102B Gene

Sources for FAM102B Gene

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