FAM102A Gene
protein-coding GIFtS : 47
GCID: GC09 M130702
family with sequence similarity 102, member A (Previous name: chromosome 9 open reading frame 132 ) (Previous symbol: C9orf132 )
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Aliasesfor FAM102A gene
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc ,
7 Ensembl ,
8 DME ,
9 miRBase ,
and/or 10 fRNAdb )About This Section Aliases Family With Sequence Similarity 102, Member A 1 2 Eeig11 C9orf1321 2 3 Chromosome 9 Open Reading Frame 1321 EEIG12 3 5 C230093N12Rik2 SYM-3A1 2 Protein FAM102A2 BA203J24.71 Sym-3 Homolog A2 Early Estrogen-Induced Gene 1 Protein2 3
Export aliases for FAM102A gene to outside databases Previous GC identifers: GC09M127786 GC09M129742 GC09M100319
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Summariesfor FAM102A gene (According to Entrez Gene ,
Tocris Bioscience ,
Wikipedia's
Gene Wiki ,
PharmGKB ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
About This Section UniProtKB/Swiss-Prot: F102A_HUMAN, Q5T9C2 Function : May play a role in estrogen action
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Genomic Viewsfor FAM102A gene
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 37) ,
and/or miRBase ,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69) ,
Regulatory elements and Epigenetics data according to
QIAGEN ,
SABiosciences , and/or
SwitchGear Genomics )About This Section RefSeq DNA sequence: NC_000009.11 NC_018920.1 NT_008470.19 Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the FAM102A gene promoter: MEF-2A MEF-2 aMEF-2 Pax-4a C/EBPalpha Other transcription factors Search SABiosciences Chromatin IP Primers for FAM102A Epigenetics: QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FAM102A
Genomic Location: Genomic View : UCSC Golden Path with GeneCards custom track Entrez Gene cytogenetic band: 9q34.11 Ensembl cytogenetic band: 9q34.11 HGNC cytogenetic band: 9q34.11 FAM102A Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc information about chromosome 9 GeneLoc Exon Structure
GeneLoc location for GC09M130702: view genomic region
(about GC identifiers )
Start:
130,702,858 bp from pter
End:
130,742,812 bp from pter
Size:
39,955 bases
Orientation:
minus strand
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Proteinsfor FAM102A gene
(According to
1 UniProtKB ,
HORDE ,
neXtProt ,
Ensembl ,
and/or Reactome ,
Modification sites according to 2 PhosphoSitePlus ,
Specific Peptides from DME ,
Protein expression images according to data from SPIRE MOPED and PaxDb ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from
EMD Millipore ,
R&D Systems ,
GenScript ,
Enzo Life Sciences ,
OriGene ,
Novus Biologicals ,
Sino Biological ,
ProSpec , and/or
Uscn ,
Biochemical Assays by
EMD Millipore ,
R&D Systems ,
OriGene ,
GenScript ,
Cell Signaling Technology ,
Enzo Life Sciences , and/or
Uscn ,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene ,
Antibodies by
EMD Millipore ,
R&D Systems ,
GenScript ,
Cell Signaling Technology ,
OriGene ,
Novus Biologicals ,
Thermo Fisher Scientific ,
Abcam , and/or
Uscn )
About This Section UniProtKB/Swiss-Prot: F102A_HUMAN, Q5T9C2 (See
protein sequence )Recommended Name: Protein FAM102A Size : 384 amino acids; 41785 Da
Sequence caution : Sequence=CAI12618.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions : A2A329 Q8TEL4Alternative splicing : 3 isoforms : Q5T9C2-1 Q5T9C2-2 Q5T9C2-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for FAM102A: NX_Q5T9C2 Post-translational modifications:
View modification sites using PhosphoSitePlus 2 View neXtProt modification sites for NX_Q5T9C2 FAM102A Protein expression data from MOPED and PaxDb : About this image
REFSEQ proteins (2 alternative transcripts):
NP_001030331.1 NP_976050.1 ENSEMBL proteins: ENSP00000362187 ENSP00000362176 Human Recombinant Protein Products: FAM102A Antibody Products: Assay Products for FAM102A:
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Protein
Domains / Familiesfor FAM102A gene (According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
About This Section
FAM102A for domains About GeneDecksing 1 InterPro domain/family :
Graphical View of Domain Structure for InterPro Entry Q5T9C2 ProtoNet protein and cluster: Q5T9C2
UniProtKB/Swiss-Prot: F102A_HUMAN, Q5T9C2 Similarity : Belongs to the FAM102 family
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Functionfor FAM102A gene
(According to 1 UniProtKB ,
Genatlas ,
LifeMap Discovery™ ,
IUBMB , and/or
2 DME ,
Human phenotypes from GenomeRNAi ,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences ,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene ,
RNAi from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
microRNA from QIAGEN ,
Gene Editing from DNA2.0 ,
Clones from EMD Millipore ,
OriGene ,
SwitchGear Genomics ,
GenScript ,
Sino Biological ,
DNA2.0 ,
and Vector BioLabs ,
Cell Lines from GenScript ,
LifeMap BioReagents ,
In Situ Hybridization Assays from Advanced Cell Diagnostics ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene .)
About This Section Function Summary: UniProtKB/Swiss-Prot: F102A_HUMAN, Q5T9C2 Function : May play a role in estrogen actionInduction : By 17-beta-estradiol but also by a group of natural and synthetic estrogens as well as by estrogenicenvironmental compounds. Repressed by the antiestrogen 4-hydroxy-tamoxifen
Clone Products: Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM102A (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM102A (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): FAM102A (NM_203305 ) Browse Sino Biological Human cDNA Clones DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM102A Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM102A
In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM102A
1 GenomeRNAi human phenotype for FAM102A :
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Pathways & Interactionsfor FAM102A gene
(Pathways according to
EMD Millipore ,
R&D Systems ,
Cell Signaling Technology ,
KEGG ,
PharmGKB ,
BioSystems ,
Reactome ,
Tocris Bioscience ,
GeneGo (Thomson Reuters) ,
QIAGEN ,
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Interaction Networks according to
SABiosciences ,
and/or STRING ,
Interactions according to 1 UniProtKB ,
2 MINT ,
3 I2D , and/or
4 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene) .
About This Section Interactions: Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAM102A 1 Interacting protein for FAM102A (Q5T9C2 3 ) via UniProtKB, MINT, STRING, and/or I2D About this table
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Drugs & Compoundsfor FAM102A gene (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
EMD Millipore , Tocris Bioscience
HMDB ,
BitterDB , and/or
Novoseek , and Drugs according to
DrugBank ,
Enzo Life Sciences , and/or
PharmGKB , with drugs/clinical trials/news
search links to CenterWatch )
About This Section Browse Tocris compounds for FAM102A Search CenterWatch for drugs/clinical trials and news about FAM102A / F102A
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Transcriptsfor FAM102A gene (Secondary structures according to
fRNAdb ,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
transcript ids from Ensembl
with links to UCSC ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from
EMD Millipore ,
siRNAs from
OriGene ,
QIAGEN ,
shRNA from
OriGene ,
microRNA from QIAGEN ,
Tagged/untagged cDNA clones from
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SwitchGear Genomics ,
GenScript ,
DNA2.0 ,
Vector BioLabs ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN
)About This Section REFSEQ mRNAs for FAM102A gene (2 alternative transcripts): NM_001035254.2 NM_203305.2 Unigene Cluster for FAM102A:
Family with sequence similarity 102, member A Hs.535972 [show with all ESTs ] Unigene Representative Sequence: NM_001035254 8 Ensembl transcripts including schematic representations, and UCSC links where relevant : ENST00000373095 (uc004bsw.1 uc004bsx.2 ) ENST00000465821 (uc004bsy.1 )ENST00000373084 ENST00000464641 ENST00000300434 ENST00000479828 ENST00000493175 ENST00000494606 Clone Products: OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM102A (see all 3 ) OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM102A (see all 2 )OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling GenScript: all cDNA clones in your preferred vector (see all 2 ): FAM102A (NM_203305 ) DNA2.0 Custom Codon Optimized Gene
Synthesis Service for FAM102A Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM102A
Additional cDNA sequence: AK058004.1 AK094350.1 AL049365.1 BC047949.1 BC137087.1 BC137088.1 BC142952.1
10 DOTS entries : DT.97817759 DT.40292167
DT.100788647 DT.446857 DT.416621 DT.99999239 DT.95306624 DT.121158852 DT.86844224 DT.91764612 24/276 AceView cDNA sequences (see all 276 ):
AI354834 BF062910 AI674737 BF447305 AI223826 AA721310 BQ890377 CD106524 Z38780 BM756091 AI633829 T12582 CB990054 AA805418 BF059477 BM458600 AA736739 CA425632 AI820042 BF928829 AK058004 AI439620 AA677893 CF541104 GeneLoc Exon Structure 3 Alternative Splicing Database (ASD) splice patterns (SP) for FAM102A About this scheme ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 SP1 :                   SP2 :                   SP3 :   -   -   -            
ECgene alternative splicing isoforms for FAM102A
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Expression for FAM102A gene
(RNA expression data according to
H-InvDB ,
NONCODE ,
miRBase , and
RNAdb ,
Expression images according to data from
BioGPS ,
Illumina Human BodyMap , and
CGAP
SAGE ,
Sets of similar genes according to GeneDecks ,
in vivo and in vitro expression data from LifeMap Discovery™ ,
plus additional links to
Genevestigator , and/or
SOURCE , and/or
BioGPS , and/or
UniProtKB ,
PCR Arrays from
SABiosciences ,
Primers from
OriGene ,
SABiosciences , and/or
QIAGEN ,
In Situ Hybridization Assays from Advanced Cell Diagnostics )
About This Section FAM102A expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this image BioGPS CGAP TAG: TGGGAGCCCT
About this image FAM102A expression in embryonic tissues and stem cells Expression by the Database of Embryonic development, Stem cell research, and
Regenerative medicine About this table 1 LifeMap In Vivo Development Anatomical Compartment/Cell Tissue Anatomical Compartment
Cell Category (developmental path) Heart Atrioventricular Canal Heart Expression: Positive Negative
Selective markerExperimental details:
Curated
Microarrays
In-situ hybridization
See FAM102A Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for FAM102A SOURCE GeneReport for Unigene cluster: Hs.535972 SABiosciences Custom PCR Arrays for FAM102A Primer Products: OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FAM102ABrowse OriGene validated miRNA SYBR primer pairs SABiosciences RT2 qPCR Primer Assay in human , mouse , rat FAM102A QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FAM102A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FAM102A In Situ Assay Products: Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM102A
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Orthologsfor FAM102A gene
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
,
5 MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase ,
and/or
6 Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam )
About This Section
This gene was present in the common ancestor of animals.
Orthologs for FAM102A gene from 6/17 species (see all 17 ) About this table
ENSEMBL Gene Tree for FAM102A (if available)TreeFam Gene Tree for FAM102A (if available)
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Paralogsfor FAM102A gene (Paralogs according to
1 HomoloGene , 2 Ensembl , and 3 SIMAP , Pseudogenes according to 4 Pseudogene.org Build 68)About This Section Paralogs for FAM102A gene FAM102B 2 1 SIMAP similar gene for FAM102A using alignment to 1 protein entry: F102A_HUMAN :FAM102B
FAM102A for paralogs About GeneDecksing
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Genomic Variantsfor FAM102A gene (SNPs/Variants according to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE ,
UniProtKB , and
DNA2.0 ,
Linkage Disequilibrium by HapMap ,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants , Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB) , Blood group antigen gene mutations by BGMUT ,
Resequencing Primers from QIAGEN ,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences )
About This Section
Genomic Data Transcription Related Data Allele Frequencies SNP ID Valid Clinical significance Chr 9 pos Sequence # AA Chg Type More # Allele freq Pop Total sample More
HapMap Linkage Disequilibrium report for FAM102A (130702858 - 130742812 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for FAM102A 1 Indel : 41911
SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FAM102A
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Disorders
/ Diseasesfor FAM102A gene
(in which this Gene is Involved, According to MalaCards ,
OMIM, UniProtKB ,
the University of Copenhagen DISEASES
database ,
Genatlas , GeneTests ,
GAD ,
HuGE Navigator ,
and/or TGDB .)
About This Section
FAM102A for disorders About GeneDecksing
OMIM gene information: 610891
OMIM disorders : --2 diseases for FAM102A : About MalaCards bronchiolitis pharyngitis 1 disease from the University of Copenhagen DISEASES database for FAM102A :Bronchiolitis Export disorders for FAM102A gene to outside databases
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Publicationsfor FAM102A gene (in
PubMed .
Associations of this gene to articles via
1 Entrez Gene ,
2 UniProtKB/Swiss-Prot ,
3 HGNC ,
4 GAD ,
5 PharmGKB ,
6 HMDB ,
7 DrugBank ,
8 UniProtKB/TrEMBL ,
9 Novoseek , and/or
10 fRNAdb )
About This Section PubMed articles for FAM102A gene integrated from 9 sources : (articles sorted by number of sources associating them with FAM102A) Utopia : connect your pdf to the dynamic world of online information
Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1. (PubMed id 14605097) 1 , 2 , 9 Wang D.Y.... Edwards E.A. (2004) DNA sequence and analysis of human chromosome 9. (PubMed id 15164053) 1 , 2 Humphray S.J.... Dunham I. (2004) The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334) 2 Gerhard D.S....Malek J. (2004) Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932) 1 Strausberg R.L....Marra M.A. (2002) Shotgun sequencing of the human transcriptome with ORF expressed sequence tags. (PubMed id 10737800) 1 Dias Neto E....Simpson A.J.G. (2000)
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External Searches for FAM102A gene
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing FAM102A gene
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
Kegg ,
and/or
H-InvDB )
About This Section
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Other Databases showing FAM102A gene
(According to HUGE )
About This Section --
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Specialized Databases showing FAM102A gene (According to PharmGKB ,
ATLAS , HORDE , IMGT , LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
Name Description
PharmGKB entry for FAM102A Pharmacogenomics, SNPs, Pathways
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About This Section Patent Information for FAM102A gene: Search GeneIP for patents involving FAM102A GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Productsfor FAM102A gene (Antibodies, recombinant proteins, and assays from EMD Millipore , R&D Systems , OriGene , QIAGEN , GenScript , Cell Signaling Technology , SABiosciences , Novus Biologicals , Sino Biological , Enzo Life Sciences , Abcam , ProSpec , Uscn , Thermo Fisher Scientific , Gene Editing from DNA2.0 , Clones from EMD Millipore , OriGene , GenScript , Sino Biological , DNA2.0 , SwitchGear Genomics , Vector BioLabs , Cell lines from GenScript and LifeMap BioReagents , PCR Arrays from SABiosciences , Drugs and/or compounds from EMD Millipore , Tocris Bioscience , and/or
Enzo Life Sciences ), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
Browse OriGene Antibodies OriGene shRNA RFP for FAM102A OriGene 29mer shRNA kits in GFP-retroviral vector in human , mouse , rat for FAM102A OriGene genome-wide validated SYBR primer pairs in human , mouse , rat for FAM102A OriGene Protein Over-expression Lysate for FAM102A Browse OriGene Fluorogenic Cell Assay Kits OriGene siRNA for FAM102A Browse 3'-UTR reporter clones for miRNA target validation OriGene untagged cDNA clones in CMV expression vector in human , mouse , rat for FAM102A OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human , mouse , rat for FAM102A Browse OriGene GFP tagged cDNA clones in CMV expression vector Browse OriGene MicroRNA Expression Plasmids Browse OriGene basic RS shRNAs Browse OriGene validated miRNA SYBR primer pairs OriGene Purified Protein for FAM102A OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling OriGene Custom Antibody Services for FAM102A OriGene Custom Protein Services for FAM102A OriGene Custom Immunoassay Development
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FAM102A QIAGEN SeqTarget long-range PCR primers in human , mouse , rat for resequencing FAM102A QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human , mouse , rat FAM102A QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human , mouse , rat FAM102A QIAGEN QuantiFast Probe-based Assays in human , mouse , rat FAM102A QIAGEN QuantiTect SYBR Green Assays in human , mouse , rat FAM102A
Search Tocris compounds for FAM102A
FAM102A Proteins, Antibodies, CLIAs, and ELISAs
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAM102A
Search ThermoFisher Antibodies for FAM102A
Vector BioLabs ready-to-use adenovirus/AAV for human , mouse , rat FAM102A
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Aliases for FAM102A
Databases for FAM102A
Disorders / Diseases for FAM102A
Domains / Families for FAM102A
Drugs / Compounds for FAM102A
Expression for FAM102A
Function for FAM102A
Genomic Views for FAM102A
Intellectual Property for FAM102A
Orthologs for FAM102A
Paralogs for FAM102A
Pathways / Interactions for FAM102A
Products for FAM102A
Proteins for FAM102A
Publications for FAM102A
Search Box for FAM102A
Summaries for FAM102A
Transcripts for FAM102A
Variants for FAM102A
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