Free for academic non-profit institutions. Other users need a Commercial license

Aliases for FAM102A Gene

Aliases for FAM102A Gene

  • Family With Sequence Similarity 102, Member A 2 3
  • EEIG1 3 4 6
  • Early Estrogen-Induced Gene 1 Protein 3 4
  • C9orf132 3 4
  • Chromosome 9 Open Reading Frame 132 2
  • Sym-3 Homolog A (C. Elegans) 2
  • Protein FAM102A 3
  • Sym-3 Homolog A 3
  • C230093N12Rik 3
  • BA203J24.7 3
  • SYM-3A 3

External Ids for FAM102A Gene

Previous Symbols for FAM102A Gene

  • C9orf132

Summaries for FAM102A Gene

GeneCards Summary for FAM102A Gene

FAM102A (Family With Sequence Similarity 102, Member A) is a Protein Coding gene. An important paralog of this gene is FAM102B.

UniProtKB/Swiss-Prot for FAM102A Gene

  • May play a role in estrogen action.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FAM102A Gene

Genomics for FAM102A Gene

Genomic Location for FAM102A Gene

Start:
127,940,579 bp from pter
End:
127,980,533 bp from pter
Size:
39,955 bases
Orientation:
Minus strand

Genomic View for FAM102A Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for FAM102A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FAM102A Gene

Regulatory Elements for FAM102A Gene

Proteins for FAM102A Gene

  • Protein details for FAM102A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q5T9C2-F102A_HUMAN
    Recommended name:
    Protein FAM102A
    Protein Accession:
    Q5T9C2
    Secondary Accessions:
    • A2A329
    • Q8TEL4

    Protein attributes for FAM102A Gene

    Size:
    384 amino acids
    Molecular mass:
    41785 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=CAI12618.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};

    Alternative splice isoforms for FAM102A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for FAM102A Gene

Proteomics data for FAM102A Gene at MOPED

Post-translational modifications for FAM102A Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FAM102A Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FAM102A Gene

Domains for FAM102A Gene

Protein Domains for FAM102A Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

F102A_HUMAN
Family:
  • Belongs to the FAM102 family.:
    • Q5T9C2
genes like me logo Genes that share domains with FAM102A: view

No data available for Gene Families for FAM102A Gene

Function for FAM102A Gene

Molecular function for FAM102A Gene

UniProtKB/Swiss-Prot Function: May play a role in estrogen action.
UniProtKB/Swiss-Prot Induction: By 17-beta-estradiol but also by a group of natural and synthetic estrogens as well as by estrogenic environmental compounds. Repressed by the antiestrogen 4-hydroxy-tamoxifen

Gene Ontology (GO) - Molecular Function for FAM102A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 25416956
genes like me logo Genes that share ontologies with FAM102A: view

Phenotypes for FAM102A Gene

GenomeRNAi human phenotypes for FAM102A:
genes like me logo Genes that share phenotypes with FAM102A: view

miRNA for FAM102A Gene

No data available for Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for FAM102A Gene

Localization for FAM102A Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for FAM102A Gene COMPARTMENTS Subcellular localization image for FAM102A gene
Compartment Confidence
cytosol 2
nucleus 2
mitochondrion 1

No data available for Gene Ontology (GO) - Cellular Components for FAM102A Gene

Pathways for FAM102A Gene

SuperPathways for FAM102A Gene

No Data Available

Gene Ontology (GO) - Biological Process for FAM102A Gene

None

No data available for Pathways by source for FAM102A Gene

Transcripts for FAM102A Gene

Unigene Clusters for FAM102A Gene

Family with sequence similarity 102, member A:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FAM102A Gene

ExUns: 1 ^ 2 ^ 3a · 3b ^ 4 ^ 5 ^ 6 ^ 7 ^ 8
SP1:
SP2:
SP3: - - -

Relevant External Links for FAM102A Gene

GeneLoc Exon Structure for
FAM102A
ECgene alternative splicing isoforms for
FAM102A

Expression for FAM102A Gene

mRNA expression in normal human tissues for FAM102A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, MOPED, and MaxQB for FAM102A Gene

SOURCE GeneReport for Unigene cluster for FAM102A Gene Hs.535972

genes like me logo Genes that share expressions with FAM102A: view

Orthologs for FAM102A Gene

This gene was present in the common ancestor of animals.

Orthologs for FAM102A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia FAM102A 36
  • 95.92 (n)
  • 95.05 (a)
FAM102A 37
  • 93 (a)
OneToOne
cow
(Bos Taurus)
Mammalia FAM102A 36
  • 91.38 (n)
  • 95.82 (a)
FAM102A 37
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia FAM102A 36
  • 89.65 (n)
  • 93.95 (a)
FAM102A 37
  • 96 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Fam102a 36
  • 87.07 (n)
  • 94.53 (a)
Fam102a 16
Fam102a 37
  • 93 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia FAM102A 37
  • 90 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia FAM102A 37
  • 87 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Fam102a 36
  • 87.76 (n)
  • 95.05 (a)
chicken
(Gallus gallus)
Aves FAM102A 36
  • 76.7 (n)
  • 85.86 (a)
FAM102A 37
  • 86 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia FAM102A 37
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia fam102a 36
  • 72.71 (n)
  • 78.93 (a)
zebrafish
(Danio rerio)
Actinopterygii fam102aa 37
  • 58 (a)
OneToMany
fam102ab 36
  • 70.66 (n)
  • 75.52 (a)
fam102ab 37
  • 71 (a)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta CG8671 37
  • 14 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea sym-3 37
  • 25 (a)
OneToMany
sea squirt
(Ciona savignyi)
Ascidiacea -- 37
  • 34 (a)
ManyToMany
-- 37
  • 33 (a)
ManyToMany
Species with no ortholog for FAM102A:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for FAM102A Gene

ENSEMBL:
Gene Tree for FAM102A (if available)
TreeFam:
Gene Tree for FAM102A (if available)

Paralogs for FAM102A Gene

Paralogs for FAM102A Gene

Selected SIMAP similar genes for FAM102A Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with FAM102A: view

Variants for FAM102A Gene

Sequence variations from dbSNP and Humsavar for FAM102A Gene

SNP ID Clin Chr 09 pos Sequence Context AA Info Type MAF
rs7859 -- 127,941,286(-) TTGGG(C/T)GGAAA utr-variant-3-prime
rs734793 -- 127,969,431(-) AGGGC(A/C)GTTAT intron-variant
rs943391 -- 127,972,538(-) gctgc(C/T)ggtgc intron-variant
rs943392 -- 127,963,162(-) CAACT(C/T)TTGGA intron-variant
rs1043060 -- 127,942,841(-) GCAGC(A/G)GCTCC utr-variant-3-prime

Structural Variations from Database of Genomic Variants (DGV) for FAM102A Gene

Variant ID Type Subtype PubMed ID
nsv893859 CNV Loss 21882294
nsv893860 CNV Gain 21882294
nsv893865 CNV Loss 21882294
dgv8287n71 CNV Loss 21882294
dgv8291n71 CNV Loss 21882294
dgv8293n71 CNV Loss 21882294
nsv466577 CNV Loss 19166990
nsv6722 CNV Insertion 18451855
nsv831727 CNV Loss 17160897
esv2739056 CNV Deletion 23290073
esv5200 CNV Deletion 18987735
esv2739057 CNV Deletion 23290073

Relevant External Links for FAM102A Gene

HapMap Linkage Disequilibrium report
FAM102A

Disorders for FAM102A Gene

(1) University of Copenhagen DISEASES for FAM102A Gene

genes like me logo Genes that share disorders with FAM102A: view

No data available for UniProtKB/Swiss-Prot for FAM102A Gene

Publications for FAM102A Gene

  1. Identification of estrogen-responsive genes by complementary deoxyribonucleic acid microarray and characterization of a novel early estrogen-induced gene: EEIG1. (PMID: 14605097) Wang D.Y. … Edwards E.A. (Mol. Endocrinol. 2004) 3 4 23
  2. DNA sequence and analysis of human chromosome 9. (PMID: 15164053) Humphray S.J. … Dunham I. (Nature 2004) 3 4
  3. Early estrogen-induced gene 1, a novel RANK signaling component, is essential for osteoclastogenesis. (PMID: 23478294) Choi H.K. … Lee S.Y. (Cell Res. 2013) 3
  4. A proteome-scale map of the human interactome network. (PMID: 25416956) Rolland T. … Vidal M. (Cell 2014) 3
  5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4

Products for FAM102A Gene

Sources for FAM102A Gene

Back to Top

Content