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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FAIM2 Gene

protein-coding   GIFtS: 52
GCID: GC12M050260

Fas apoptotic inhibitory molecule 2
 Explore 11 diseases affiliated with
FAIM2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FAIM2    

Aliases
for FAIM2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Fas Apoptotic Inhibitory Molecule 21 2 3     Neural Membrane Protein 352 3
LFG1 2 3 5     Transmembrane BAX Inhibitor Motif-Containing Protein 22 3
NMP351 2 3 5     LIFEGUARD1
LFG21 2 3     NGP352
TMBIM21 2 3     Protein Lifeguard 22
KIAA09501 3     

External Ids:    HGNC: 170671   Entrez Gene: 230172   Ensembl: ENSG000001354727   OMIM: 6043065   UniProtKB: Q9BWQ83   

Export aliases for FAIM2 gene to outside databases

Previous GC identifers: GC12M050517 GC12M050316 GC12M049977 GC12M048546 GC12M047291


Summaries
for FAIM2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
UniProtKB/Swiss-Prot: LFG2_HUMAN, Q9BWQ8
Function: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated
apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting
cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development




Genomic Views
for FAIM2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_029419.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FAIM2 gene promoter:
         RP58   Pax-5   Pbx1a   GCNF   RelA   LCR-F1   GCNF-1   GCNF-2   Hlf   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FAIM2 promoter sequence
   Search SABiosciences Chromatin IP Primers for FAIM2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FAIM2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12q13   Ensembl cytogenetic band:  12q13.12   HGNC cytogenetic band: 12q13

FAIM2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAIM2 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M050260:  view genomic region     (about GC identifiers)

Start:
 50,260,679 bp from pter      End:
 50,298,000 bp from pter
Size:
 37,322 bases      Orientation:
 minus strand

Proteins
for FAIM2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: LFG2_HUMAN, Q9BWQ8 (See protein sequence)
Recommended Name: Protein lifeguard 2  
Size: 316 amino acids; 35110 Da
Subunit: Interacts with FAS/TNFRSF6 and BAX
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity). Membrane raft. Cell junction,
synapse, postsynaptic cell membrane (By similarity)
Sequence caution: Sequence=AAF06327.1; Type=Frameshift; Positions=82, 130; Sequence=BAA76794.1; Type=Erroneous
initiation; Note=Translation N-terminally shortened;
Secondary accessions: A8K1W6 Q9UJY9 Q9Y2F7

Explore the universe of human proteins at neXtProt for FAIM2: NX_Q9BWQ8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9BWQ8

    • FAIM2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_036438.2  
    ENSEMBL proteins: 
     ENSP00000321951   ENSP00000450132   ENSP00000447715   ENSP00000449711   ENSP00000446771  
     ENSP00000449957   ENSP00000449360  

    Human Recombinant Protein Products: 
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    Novus Biologicals FAIM2 Lysate
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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for FAIM2

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005575cellular_component ND--
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--
    GO:0030054cell junction IEA--
    GO:0045121membrane raft IDA17635665


    FAIM2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for FAIM2

    Protein Domains /
    Families
    for FAIM2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FAIM2 for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR006214 Bax_inhibitor_1-related

    Graphical View of Domain Structure for InterPro Entry Q9BWQ8

    ProtoNet protein and cluster: Q9BWQ8

    UniProtKB/Swiss-Prot: LFG2_HUMAN, Q9BWQ8
    Similarity: Belongs to the BI1 family. LFG subfamily


    Function
    for FAIM2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: LFG2_HUMAN, Q9BWQ8
    Function: Antiapoptotic protein which protects cells uniquely from Fas-induced apoptosis. Regulates Fas-mediated
    apoptosis in neurons by interfering with caspase-8 activation. May play a role in cerebellar development by affecting
    cerebellar size, internal granular layer (IGL) thickness, and Purkinje cell (PC) development
    Induction: Regulated by the AKT1/LEF1 pathway in breast cancer cell lines

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAIM2
    8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate FAIM2 (see all 47):
    hsa-miR-193a-3p hsa-miR-330-5p hsa-miR-106a hsa-miR-578 hsa-miR-449a hsa-miR-105 hsa-miR-890 hsa-miR-3161
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAIM2 (see all 7)
    OriGene siRNA: FAIM2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAIM2

    Gene Editing
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    Clone
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAIM2 

    Cell Line
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    Search LifeMap BioReagents cell lines for FAIM2

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAIM2

    Animal Models:
         Mouse knock-out Faim2tm1.1Jbsc for FAIM2
         4 MGI mutant phenotypes (inferred from 2 alleles) (MGI details for Faim2):
     behavior/neurological  homeostasis/metabolism  nervous system  renal/urinary system 

    FAIM2 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for FAIM2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1TRAIL signaling pathway
    		FAS (CD95) signaling pathway0.30


    1 BioSystems Pathway for FAIM2 
        FAS (CD95) signaling pathway


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FAIM2

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for FAIM2 (Q9BWQ83 ENSP000003219514) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    FASP254453, ENSP000003479794I2D: score=3 STRING: ENSP00000347979
    About this table

    Gene Ontology (GO): 5/8 biological process terms (GO ID links to tree view) (see all 8):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IEA--
    GO:0007417central nervous system development ----
    GO:0021549cerebellum development ISS--
    GO:0021680cerebellar Purkinje cell layer development ISS--
    GO:0021681cerebellar granular layer development ISS--


    FAIM2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FAIM2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FAIM2
    Search CenterWatch for drugs/clinical trials and news about FAIM2 / LFG2 

    Transcripts
    for FAIM2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FAIM2 gene: 
    NM_012306.3  

    Unigene Cluster for FAIM2:

    Fas apoptotic inhibitory molecule 2
    Hs.567424  [show with all ESTs]
    Unigene Representative Sequence: NM_012306
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000320634(uc001rvi.2 uc001rvj.2) ENST00000550890 ENST00000550195
    ENST00000550635 ENST00000552669 ENST00000552863 ENST00000547871

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FAIM2
    8/47 QIAGEN miScript miRNA Assays for microRNAs that regulate FAIM2 (see all 47):
    hsa-miR-193a-3p hsa-miR-330-5p hsa-miR-106a hsa-miR-578 hsa-miR-449a hsa-miR-105 hsa-miR-890 hsa-miR-3161
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FAIM2 (see all 7)
    OriGene siRNA: FAIM2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FAIM2
    Clone
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    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FAIM2
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    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FAIM2
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FAIM2

    Additional cDNA sequence: 

    AB023167.1 AF190461.1 AK090728.1 AK290031.1 BC000051.2 BX647219.1 

    6 DOTS entries:

    DT.448734  DT.100756470  DT.75159893  DT.100772514  DT.121190998  DT.92035070 

    24/221 AceView cDNA sequences (see all 221):

    AI816238 BX493713 AL707764 CB152140 BI827282 BQ272446 BX376124 CD674724 
    CB850833 CB153566 BQ130552 AL118922 AL133893 BU074238 AI468058 CR615657 
    AB023167 BQ717776 CR599086 CK300444 BQ066891 BM695237 BU782593 CR622004 

    GeneLoc Exon Structure


    Expression
    for FAIM2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FAIM2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGGCTGGAGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FAIM2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 4 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor 7SMOO32 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ mesenchymal progenitor 7PEND24 (Embryonic Progenitor Cell)Cartilage, Neural Crest
    PureStem™ progenitor SM22 (Embryonic Progenitor Cell)
    PureStem™ progenitor W10 (Embryonic Progenitor Cell)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See FAIM2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FAIM2

    SOURCE GeneReport for Unigene cluster: Hs.567424

    UniProtKB/Swiss-Prot: LFG2_HUMAN, Q9BWQ8
    Tissue specificity: Highly expressed in breast carcinoma tissues. Enhanced expression correlates with the grade of the
    tumor (grade II/grade III) in primary breast tumors (at protein level). Widely expressed. Expressed at high levels in
    the brain especially in the hippocampus

        SABiosciences Expression via Pathway-Focused PCR Array including FAIM2: 
              Apoptosis 384HT in human mouse rat

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    In Situ
    Assay Products:     
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    Orthologs
    for FAIM2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for FAIM2 gene from 6/20 species (see all 20)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves FAIM21 Fas apoptotic inhibitory molecule 2 75.56(n)
    75.56(a)    		   426899  XM_424507.3  XP_424507.1 
    lizard
    (Anolis carolinensis)    		 Reptilia FAIM26
    		 --
    		 69(a)
    		 1 ↔ 1
    		 2(96044362-96082457)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.48322 Xenopus laevis transcribed sequence with weak similarity more 71.06(n)    48040039 
    zebrafish
    (Danio rerio)    		 Actinopterygii BM264711.12   -- 71.34(n)    BM264711.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta CG303796
    CG336736
    		 --
    		 26(a)
    23(a)
    		 1 ↔ many
    possible ortholog
    		 2R(3827461-3829375)
    2L(1945815-1946728)
    worm
    (Caenorhabditis elegans)    		 Secernentea tag-1201 Protein TAG-120 48.55(n)
    43.04(a)    		   179362  NM_073100.5  NP_505501.1 


    ENSEMBL Gene Tree for FAIM2 (if available)
    TreeFam Gene Tree for FAIM2 (if available) 

    Paralogs
    for FAIM2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FAIM2 gene
    TMBIM42  TMBIM12  GRINA2  ENSG000002281442  
    5 SIMAP similar genes for FAIM2 using alignment to 6 protein entries:     LFG2_HUMAN (see all proteins):
    GRINA    RECS1    TMBIM1    TMBIM4    MDS013

    FAIM2 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for FAIM2
    PGOHUM00000232916


    Genomic Variants
    for FAIM2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/887 NCBI SNPs in FAIM2 are shown (see all 887)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 12 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs1866819471,2
    		--50260220(+) ATCTAA/CCCACC 1 -- ds50010--------
    rs73052291,2
    		C,F,A,H,--50260264(+) AGCCAC/TTGAGC 1 -- ds500110Minor allele frequency- T:0.44NA WA CSA EA 255
    rs1467982311,2
    		--50260311(+) GGACAA/GTCTGT 1 -- ds50010--------
    rs1405045281,2
    		--50260416(+) CAAACA/GGACAG 1 -- ds50010--------
    rs1910927801,2
    		--50260429(+) TTCCAC/TAGAAA 1 -- ds50010--------
    rs761905611,2
    		F,--50260453(+) GTTCCG/AGAGGA 1 -- ds50011Minor allele frequency- A:0.03WA 118
    rs558969331,2
    		C--50260466(+) CTCTGG/TGATTG 1 -- ds50011Minor allele frequency- T:0.50WA 2
    rs1166397001,2
    		F,--50260520(+) GAGCAG/AGAGAA 1 -- ds50011Minor allele frequency- A:0.02WA 118
    rs1826972291,2
    		--50260607(+) ACACAA/GGTCCG 1 -- ds50010--------
    rs1879404501,2
    		--50260635(+) CTCCAC/TGACCA 1 -- ds50010--------

    HapMap Linkage Disequilibrium report for FAIM2 (50260679 - 50298000 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for FAIM2
         2 CNVs: 101513 61240
         1 Indel: 63012

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FAIM2
    DNA2.0 Custom Variant and Variant Library Synthesis for FAIM2

    Disorders / Diseases
    for FAIM2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FAIM2 for disorders           About GeneDecksing

    OMIM gene information: 604306    OMIM disorders: --

    11 diseases for FAIM2:    About MalaCards
    alopecia universalis    nevus    alopecia    pharyngitis
    breast cancer    asthma    obesity    malaria
    neuronitis    breast carcinoma    carcinoma

    Human Genome Epidemiology (HuGE) Navigator: FAIM2 (9 documents)

    Export disorders for FAIM2 gene to outside databases

    Publications
    for FAIM2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FAIM2 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with FAIM2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. LFG: an anti-apoptotic gene that provides protection from fas- mediated cell death. (PubMed id 10535980)1, 2, 3 Somia N.V....Verma I.M. (1999)
    2. Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10231032)1, 2, 3 Nagase T.... Ohara O. (1999)
    3. The anti-apoptotic protein lifeguard is expressed in breast cancer cells and tissues. (PubMed id 20336406)1, 2 Bucan V....Vogt P.M. (2010)
    4. Lifeguard/neuronal membrane protein 35 regulates Fas ligand-mediated apoptosis in neurons via microdomain recruitment. (PubMed id 17635665)1, 2 FernA!ndez M....CeA+a V. (2007)
    5. Sequence analysis shows that Lifeguard belongs to a new evolutionarily conserved cytoprotective family. (PubMed id 16964429)1, 2 Reimers K....Vogt P.M. (2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. Genome-wide association study of obsessive-compulsive disorder. (PubMed id 22889921)1 Stewart S.E....Pauls D.L. (2012)
    9. Antiapoptotic protein Lifeguard is required for survi val and maintenance of Purkinje and granular cells. (PubMed id 21957071)1 Hurtado de Mendoza T....Verma I.M. (2011)
    10. Genome-wide population-based association study of extr emely overweight young adults--the GOYA study. (PubMed id 21935397)1 Paternoster L....Sorensen T.I. (2011)

    External Searches for FAIM2 gene

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    Genome Databases showing FAIM2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 23017 HGNC: 17067 AceView: FAIM2 Ensembl:ENSG00000135472 euGenes: HUgn23017
    ECgene: FAIM2 H-InvDB: FAIM2

    Other Databases showing FAIM2 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0950

    Specialized Databases showing FAIM2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
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    NameDescription
    PharmGKB entry for FAIM2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
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