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Aliases & Descriptions for FAIM
(According to
1 HGNC ,
2 Entrez Gene ,
3 UniProtKB/Swiss-Prot ,
4 UniProtKB/TrEMBL , 5 OMIM , 6 GeneLoc
, and/or 7 Ensembl ,
8 miRBase )About This Section
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Aliases FAIM1 1 , 2 , 3 FLJ10582 1
Descriptions Fas apoptotic inhibitory molecule 2
Search outside databases for aliases for FAIM genePrevious GC identifers: GC03P135281 GC03P139129 GC03P139609 GC03P139648
Summaries for FAIM (According to Entrez Gene ,
Wikipedia's
Gene Wiki ,
UniProtKB/Swiss-Prot ,
and/or
UniProtKB/TrEMBL )
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UniProtKB/Swiss-Prot: FAIM1_HUMAN, Q9NVQ4 Function : Plays a role as an inducible effector molecule that mediates Fas resistance produced bysurface Ig engagement in B cells (By similarity)
Genomic Location for FAIM
(According to
GeneLoc and/or
HGNC , and/or
Entrez Gene (NCBI build 36) ,
and/or miRBase ,
Genomic Views according to
UCSC and
Ensembl ,
Transcription factor binding sites according to
SABiosciences )About This Section
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Genomic View : UCSC Golden Path with GeneCards custom track Transcription factor binding sites upstream to the FAIM gene Entrez Gene cytogenetic band: 3q22.3 Ensembl cytogenetic band: 3q22.3 HGNC cytogenetic band: 3q23 FAIM Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different) GeneLoc gene densities for chromosome 3 GeneLoc Exon Structure
GeneLoc location for GC03P139810:
(about GC identifiers )
Start:
139,810,232 bp from pter
End:
139,834,908 bp from pter
Size:
24,677 bases
Orientation:
plus strand
RefSeq DNA sequence: NC_000003.10 NT_005612.15 Proteins for FAIM
(According to
1 UniProtKB ,
and/or Ensembl ,
Phosphorylation sites according to 2 Phosphosite ,
RefSeq according to NCBI ,
PDB rendering according to OCA and/or Proteopedia ,
Recombinant Proteins
from Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Enzo Life Sciences ,
Abnova ,
OriGene and/or,
Abcam ,
Biochemical Assays by
Invitrogen ,
Millipore ,
R&D Systems ,
Cell Signaling Technology , and/or
Enzo Life Sciences ,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene ,
Antibodies by Invitrogen ,
Millipore ,
Sigma-Aldrich ,
R&D Systems ,
Cell Signaling Technology ,
Abcam ,
Abnova , and/or
Novus Biologicals )
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UniProtKB/Swiss-Prot: FAIM1_HUMAN, Q9NVQ4 (See
protein sequence )Recommended Name: Fas apoptotic inhibitory molecule 1 Size : 179 amino acids; 20215 DaAlternative splicing : 2 isoforms : Q9NVQ4-1 Q9NVQ4-2
Post-translational modifications:
View phosphorylation sites using PhosphoSite 2
REFSEQ proteins (4 alternative transcripts):
NP_001028202.1 NP_001028203.1 NP_001028204.1 NP_060617.1 ENSEMBL proteins: ENSP00000342805 ENSP00000376756 ENSP00000353775 ENSP00000376754 ENSP00000376755 ENSP00000311882 Human Recombinant Proteins               OriGene Purified Recombinant Human Protein: FAIM Antibodies for FAIM: Assays for FAIM:
Protein
Domains/ Families for FAIM(According to InterPro , ProtoNet ,
UniProtKB , and/or BLOCKS ,
Sets of similar genes according to GeneDecks )
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Graphical View of Domain Structure for InterPro Entry Q9NVQ4 ProtoNet protein and cluster: Q9NVQ4
1 Blocks protein family : IPB010695 Fas apoptotic inhibitory molecule UniProtKB/Swiss-Prot: FAIM1_HUMAN, Q9NVQ4 Similarity : Belongs to the FAIM1 family
Gene Function for FAIM
(According to MGI Jun 06 2009, UniProtKB ,
IUBMB ,and/or Genatlas ,
shRNA from
OriGene ,
Sigma-Aldrich , RNAi from
Sigma-Aldrich ,
RNAi Products ,
Clones , and
Q-PCR Products
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Millipore ,
OriGene , and/or
Abnova ,
siRNAs from
Applied Biosystems ,
SYBR primers from OriGene ,
Cell-based Assays from Millipore ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4 ): NM_001033030 Applied Biosystems Silencer ® siRNAs for FAIM Sigma-Aldrich siRNA for FAIM Sigma-Aldrich shRNA for FAIM Explore Sigma-Aldrich super-pooled esiRNAs                OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_001033030                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_001033030                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_001033030  Primers: Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers               OriGene genome-wide validated SYBR primer pairs: NM_001033030 UniProtKB/Swiss-Prot: FAIM1_HUMAN, Q9NVQ4 Function : Plays a role as an inducible effector molecule that mediates Fas resistance produced bysurface Ig engagement in B cells (By similarity)
Pathways & Interactions for FAIM
(Pathways according to Invitrogen
(maps by GeneGo ),
Millipore ,
Cell Signaling Technology ,
Sigma-Aldrich ,
KEGG
and/or UniProtKB ,
Sets of similar genes according to GeneDecks ,
Proteins Network according to
SABiosciences ,
Interactions according to 1 UniProtKB ,
2 MINT , and/or
3 STRING ,
with links to IntAct and
Ensembl ,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene .)
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4 Interacting proteins for FAIM (ENSP00000342805 3 ) via UniProtKB, MINT, and/or STRING About this table 1 Gene Ontology (GO) biological process term (links to tree view) :
GO ID Qualified GO term Evidence PubMed IDs GO:0043066 negative regulation of apoptosis
IEA --
About this table
Drugs & Compounds for FAIM (Chemical Compounds according to UniProtKB , Enzo Life Sciences ,
Sigma-Aldrich , Tocris Bioscience , and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB )
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Browse Tocris compounds for FAIM
Transcripts for FAIM(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank , RefSeq according to Entrez Gene ,
DOTS (version 10), and/or
AceView ,
non coding RNAs according to
RNAdb ,
ESTs according to GeneTide ,
exon structure from GeneLoc ,
alternative splicing isoforms according to ASD and/or
ECgene ,
RNAi Products from Invitrogen ,
Millipore , and/or
Abnova ,
siRNAs from Applied Biosystems ,
Sigma-Aldrich ,
shRNA from
Sigma-Aldrich ,
OriGene ,
Tagged/untagged cDNA clones from
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               OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 4 ): NM_001033030 Sigma-Aldrich siRNA for FAIM Sigma-Aldrich shRNA for FAIM Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer ® siRNAs: NM_001033030 NM_001033031 NM_001033032 NM_018147
REFSEQ mRNAs for FAIM gene (4 alternative transcripts): NM_001033030.1 NM_001033031.1 NM_001033032.1 NM_018147.2
Applied Biosystems TaqMan ® Gene Expression Assays: NM_001033030 NM_001033031 NM_001033032 NM_018147
               OriGene GFP tagged cDNA clones in CMV expression vector (see all 4 ): NM_001033030                                  Myc/DDK tagged cDNA clones in CMV expression vector (see all 4 ): NM_001033030                                  untagged cDNA clones in CMV expression vector (see all 4 ): NM_001033030  
Additional cDNA sequence: AK001444.1 BC012478.1 CR457122.1
8 DOTS entries : DT.100751537 DT.448180 DT.102824326 DT.91796358 DT.97843714 DT.120861339 DT.120861350 DT.95152126
24/79 AceView cDNA sequences (see all 79
):BG257592 BU689607 AI991755 BM689613 AI095903 BM668657 AA885228 BM676763 BQ045388 AV725889 CD677046 AW118945 AI745532 AA099588 BU738945 BM661587 CB163156 CA841096 BC012478 BM794937 AA477027 AI339589 BM703907 BE765628
highest scoring ESTs for FAIM :AI190311 AA026060 AA043990 AA099194 AA099588 AA126463 AA476917 AA477027 AA662664 AA688289
Unigene Cluster for FAIM: Fas apoptotic inhibitory molecule Hs.173438 [show with all ESTs ] Unigene Representative Sequence: NM_001033030 GeneLoc Exon Structure 5/6 Alternative Splicing Database (ASD) splice patterns (SP) for FAIM (see all 6
) ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6a · 6b ^ 7a · 7b ^ 8a · 8b · 8c ^ 9a · 9b SP1 :         -     -   -                   SP2 :         -   -   -   -             -       SP3 :         -   -     -                   SP4 :           -   -   -             -       SP5 :   -   -   -   -   -   -   -                  
About this scheme ECgene alternative splicing isoforms for FAIM 6 Ensembl transcripts including schematic representations : ENST00000338446
ENST00000393036
ENST00000360570
ENST00000393034
ENST00000393035
ENST00000311126
Expression for FAIM
(Experimental results according to
1 GeneNote
and GNF BioGPS ,
probe sets-to-genes annotations according to
2 GeneAnnot ,
3 GeneTide ,
Sets of similar genes according to GeneDecks ,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP ,
plus additional links to
SOURCE , and/or
GNF
BioGPS , and/or
EXPOLDB , and/or
UniProtKB ,
Expression Assays from
Applied Biosystems
)
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FAIM expression in normal and diseased human tissues Applied Biosystems TaqMan ® Gene Expression Assays for FAIM 1 / 2 / 3
3 probe-sets matching FAIM gene Data from
(Publications) and GNF BioGPS About these images About these images CGAP SAGE TAG: AAACTAACATSOURCE GeneReport for Unigene cluster: Hs.173438
Orthologs for FAIM
(Orthologs according to
1,2 HomoloGene (2 older version, for species not in 1 newer version),
3 euGenes ,
4 SGD
and/or
5 MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase ,
Gene Trees according to Ensembl )
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Orthologs for FAIM gene from 5/13 species (see all 13
)
About this table Species with no ortholog for FAIM ENSEMBL Gene Tree for FAIM Paralogs for FAIM (Paralogs according to 1 HomoloGene and 2 Ensembl , Pseudogenes according to 3 Pseudogene.org )About This Section
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--
SNPs/Variants for FAIM (According to the
1 NCBI SNP Database ,
2 Ensembl ,
3 PupaSUITE , and
UniProtKB ,
Linkage Disequilibrium by HapMap ,
Genotyping Reagents from
Applied Biosystems )
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HapMap Linkage Disequilibrium images for FAIM (up to first 250kb)
Disorders & Mutations for FAIM
(in which this Gene is Involved, According to
OMIM, UniProtKB ,
PharmGKB ,
Genatlas , GeneTests ,
Blood group antigen gene mutations by BGMUT ,
HGMD, GAD ,
HuGE Navigator ,
BCGD ,
and/or TGDB .)
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--
Medical News for FAIM (Possibly Related Articles in
Doctor's Guide )
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Publications for FAIM (in
PubMed .
Associations of this gene to articles via
1 Novoseek ,
2 HGNC ,
3 Entrez Gene ,
4 UniProtKB/Swiss-Prot ,
5 UniProtKB/TrEMBL ,
6 GAD , and/or
7 PharmGKB )
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9 PubMed articles for FAIM gene :
Search for FAIM
(in PubMed ,
OMIM , and NCBI Bookshelf ) About This Section
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Genome Databases showing FAIM
(According to
Entrez Gene ,
HGNC ,
AceView ,
euGenes ,
Ensembl ,
miRBase ,
ECgene ,
and/or
H-InvDB )
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Other Databases showing FAIM
(According to HUGE )
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Specialized Databases showing FAIM (According to ATLAS , HORDE , IMGT , MTDB, LEIDEN , UniProtKB/Swiss-Prot , and/or UniProtKB/TrEMBL ,Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot )About This Section
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-- Services for FAIM (Reagents available from Applied Biosystems , Antibodies and assays by Cell
Signaling Technology , Abcam , Novus Biologicals ,Sigma-Aldrich , R&D Systems , Millipore , Abnova , and/or Invitrogen , Clones available from OriGene ,and/or Invitrogen , Drugs and/or compounds by Sigma-Aldrich , Enzo Life Sciences , and/or Tocris Bioscience )About This Section
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Products for FAIM:
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