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Aliases &
Descriptions
for FAHD2B
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
|
| Aliases |
|---|
| DKFZp434N062 1, 2 | | EC 3.-.-.- 3 |
| | | Descriptions |
|---|
| fumarylacetoacetate hydrolase domain containing 2B 2 |
|
| |
Search outside databases for aliases for FAHD2B gene |
Summaries
for FAHD2B(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| UniProtKB/Swiss-Prot: FAH2B_HUMAN, Q6P2I3Function: May have hydrolase activity (By similarity) |
Genomic Location
for FAHD2B
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 2q11.2 Ensembl cytogenetic band: 2q11.2 HGNC cytogenetic band: 2q11.2FAHD2B Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome 2 GeneLoc Exon Structure GeneLoc location for GC02M097114:
(about GC identifiers)
Start:
|
97,113,050 bp from pter |
End:
|
97,124,309 bp from pter |
Size:
|
11,260 bases |
Orientation:
|
minus strand |
| Proteins
for FAHD2B
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: FAH2B_HUMAN, Q6P2I3 (See
protein sequence)Recommended Name: Fumarylacetoacetate hydrolase domain-containing protein 2B Size: 314 amino acids; 34613 Da
Cofactor: Calcium (Probable)
Cofactor: Magnesium (Probable)
Secondary accessions: Q8NDK1REFSEQ proteins: NP_955368.1
ENSEMBL proteins: ENSP00000272610
Human Recombinant Proteins  OriGene Purified Recombinant Human Protein: FAHD2B 
Antibodies for FAHD2B:
Assays for FAHD2B: | Protein
Domains/
Families
for FAHD2B(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| - Graphical View of Domain Structure for InterPro Entry Q6P2I3
ProtoNet protein and cluster: Q6P2I3 1 Blocks protein family: IPB002529 Fumarylacetoacetate (FAA) hydrolase
UniProtKB/Swiss-Prot: FAH2B_HUMAN, Q6P2I3Similarity: Belongs to the FAH family | Gene Function
for FAHD2B
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): XM_015428
 Applied Biosystems Silencer® siRNAs for FAHD2B
 Sigma-Aldrich siRNA for FAHD2B
Sigma-Aldrich shRNA for FAHD2B
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_199336
Myc/DDK tagged cDNA clone in CMV expression vector: NM_199336
untagged cDNA clone in CMV expression vector: NM_199336
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_199336
UniProtKB/Swiss-Prot: FAH2B_HUMAN, Q6P2I3Function: May have hydrolase activity (By similarity)Enzyme Number (IUBMB): EC 3.-.-.- 3 Gene Ontology (GO) molecular function terms (links to tree view): About this table | Pathways & Interactions
for FAHD2B
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
|
--1 Gene Ontology (GO) biological process term (links to tree view): | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0008152 | metabolic process |
IEA | -- |
About this table
|
Drugs & Compounds
for FAHD2B(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
|
 Browse Tocris compounds for FAHD2B
|
Transcripts
for FAHD2B(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vectors (see all 2): XM_015428
Sigma-Aldrich siRNA for FAHD2B
Sigma-Aldrich shRNA for FAHD2B
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_199336 REFSEQ mRNAs for FAHD2B gene: NM_199336.1
OriGene GFP tagged cDNA clone in CMV expression vector: NM_199336
Myc/DDK tagged cDNA clone in CMV expression vector: NM_199336
untagged cDNA clone in CMV expression vector: NM_199336
24/57 AceView cDNA sequences (see all 57
):BG680706 AL833869 BM663019 BU679698 BC064511 BI756332 BX282113 BM906221 NM_199336 BX282424 CD678752 AA811294 BM801603 AI458002 BI829546 BG700302 BI752152 BG708179 BI819369 BM685488 BM909255 AI692720 BU856372 BQ921365
 highest scoring ESTs for FAHD2B:BU955242 BF433876 BM547131 BC064511 BE275625 BF528040 BG284089 BG680706 BG700302 BG708179
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000272610
|
Expression
for FAHD2B
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| FAHD2B expression in normal and diseased human tissues
1 / 2 / 3 1 probe-set matching FAHD2B gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
|
Orthologs
for FAHD2B
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
|
Orthologs for FAHD2B gene from 4 species
| Organism |
Gene |
Locus |
Description |
Human
Similarity |
NCBI accessions |
chimpanzee
(Pan troglodytes) |
FAHD2B1 |
-- |
fumarylacetoacetate hydrolase domain containing 2B |
99.15(n)
99.04(a) |
459557 XM_001153120.1 XP_001153120.1 |
tropical clawed frog
(Silurana tropicalis) |
Str.188322 |
-- |
Transcribed sequence with weak similarity to protein more |
77.86(n) |
CF378324.1 |
rice blast fungus
(Magnaporthe grisea) |
MGG_059151 |
-- |
hypothetical protein |
49.14(n)
38.89(a) |
2684060 XM_369549.2 XP_369549.2 |
bread mold
(Neurospora crassa) |
NCU08018.11 |
-- |
hypothetical protein |
50.74(n)
38.92(a) |
2710596 XM_328723.1 XP_328724.1 |
About this table Species with no ortholog for FAHD2B
ENSEMBL Gene Tree for FAHD2B | Paralogs
for FAHD2B(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for FAHD2B gene
- FAHD12 FAHD2A2
|
SNPs/Variants
for FAHD2B(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
|
HapMap Linkage Disequilibrium images for FAHD2B (up to first 250kb)
|
Disorders & Mutations
for FAHD2B
(in which this Gene is Involved, According to
OMIM, UniProtKB,
PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
| -- |
Medical News
for FAHD2B(Possibly Related Articles in
Doctor's Guide)
About This Section
| -- |
Publications
for FAHD2B (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 4 PubMed articles for FAHD2B gene: |
Search for FAHD2B
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing FAHD2B
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
|
| Other Databases showing FAHD2B
(According to HUGE)
About This Section
| -- |
Specialized Databases showing FAHD2B(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| About This Section
| --
| Services
for FAHD2B(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
| 
Products for FAHD2B:
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