Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



FAHD2A Gene

protein-coding   GIFtS: 52
GCID: GC02P096068

Fumarylacetoacetate Hydrolase Domain Containing 2A

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Fumarylacetoacetate Hydrolase Domain Containing 2A1 2
Fumarylacetoacetate Hydrolase Domain Containing 12
Fumarylacetoacetate Hydrolase Domain-Containing Protein 2A2
EC 3.-.-.-3

External Ids:    HGNC: 242521   Entrez Gene: 510112   Ensembl: ENSG000001150427   UniProtKB: Q96GK73   
ORGUL members:         

Export aliases for FAHD2A gene to outside databases

Previous GC identifers: GC02P095490 GC02P090095


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for FAHD2A Gene:
FAHD2A (fumarylacetoacetate hydrolase domain containing 2A) is a protein-coding gene. Diseases associated with FAHD2A include obesity, and tuberculosis. GO annotations related to this gene include hydrolase activity. An important paralog of this gene is FAHD2B.

UniProtKB/Swiss-Prot: FAH2A_HUMAN, Q96GK7
Function: May have hydrolase activity (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
RefSeq DNA sequence:
NC_000002.12  NT_005403.18  NC_018913.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the FAHD2A gene promoter:
         PPAR-gamma1   Tal-1   FOXO3a   PPAR-gamma2   XBP-1   TGIF   Tal-1beta   ITF-2   E47   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFAHD2A promoter sequence
   Search Chromatin IP Primers for FAHD2A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAHD2A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q11.2   Ensembl cytogenetic band:  2q11.1   HGNC cytogenetic band: 2q11.2

FAHD2A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FAHD2A gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P096068:  view genomic region     (about GC identifiers)

Start:
96,068,448 bp from pter      End:
96,082,364 bp from pter
Size:
13,917 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: FAH2A_HUMAN, Q96GK7 (See protein sequence)
Recommended Name: Fumarylacetoacetate hydrolase domain-containing protein 2A  
Size: 314 amino acids; 34596 Da
Cofactor: Calcium (Probable)
Cofactor: Magnesium (Probable)
Secondary accessions: Q9Y3B0

Explore the universe of human proteins at neXtProt for FAHD2A: NX_Q96GK7

Explore proteomics data for FAHD2A at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys203, Lys224
  • Modification sites at PhosphoSitePlus

  • See FAHD2A Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_057128.2  
    ENSEMBL proteins: 
     ENSP00000405148   ENSP00000406424   ENSP00000233379   ENSP00000390528  

    FAHD2A Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein for FAHD2A
    OriGene Protein Over-expression Lysate for FAHD2A
    OriGene MassSpec for FAHD2A
    OriGene Custom Protein Services for FAHD2A
    GenScript Custom Purified and Recombinant Proteins Services for FAHD2A
    Novus Biologicals FAHD2A Protein
    Novus Biologicals FAHD2A Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for FAHD2A

    FAHD2A Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for FAHD2A
    OriGene Custom Antibody Services for FAHD2A
    Novus Biologicals FAHD2A Antibodies
    Abcam antibodies for FAHD2A
    Cloud-Clone Corp. Antibodies for FAHD2A
    ThermoFisher Antibodies for FAHD2A
    LSBio Antibodies in human, mouse, rat for FAHD2A

    FAHD2A Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for FAHD2A
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FAHD2A
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for FAHD2A
    Cloud-Clone Corp. CLIAs for FAHD2A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    2 InterPro protein domains:
     IPR002529 Fumarylacetoacetase_C
     IPR011234 Fumarylacetoacetase_C-rel

    Graphical View of Domain Structure for InterPro Entry Q96GK7

    ProtoNet protein and cluster: Q96GK7

    1 Blocks protein domain: IPB002529 Fumarylacetoacetate (FAA) hydrolase

    UniProtKB/Swiss-Prot: FAH2A_HUMAN, Q96GK7
    Similarity: Belongs to the FAH family


    FAHD2A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FAH2A_HUMAN, Q96GK7
    Function: May have hydrolase activity (By similarity)

         Enzyme Number (IUBMB): EC 3.-.-.-1

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003824catalytic activity ----
    GO:0016787hydrolase activity IEA--
    GO:0046872metal ion binding IEA--
         
    FAHD2A for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Fahd2a):
     cellular  hematopoietic system 

    FAHD2A for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAHD2A
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAHD2A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for FAHD2A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FAHD2A

    miRNA
    Products:
        
    miRTarBase miRNAs that target FAHD2A:
    hsa-mir-26b-5p (MIRT028898), hsa-mir-186-5p (MIRT045118)

    Block miRNA regulation of human, mouse, rat FAHD2A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FAHD2A
    SwitchGear 3'UTR luciferase reporter plasmidFAHD2A 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for FAHD2A
    Predesigned siRNA for gene silencing in human, mouse, rat FAHD2A

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for FAHD2A

    Clone
    Products:
         
    OriGene clones in human, mouse for FAHD2A (see all 7)
    OriGene ORF clones in mouse, rat for FAHD2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAHD2A (NM_016044)
    Sino Biological Human cDNA Clone for FAHD2A
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAHD2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAHD2A

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for FAHD2A
    Browse ESI BIO Cell Lines and PureStem Progenitors for FAHD2A 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAHD2A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    mitochondrion3
    cytosol1

    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus




        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for FAHD2A
    Interactions:

        Search GeneGlobe Interaction Network for FAHD2A

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for FAHD2A (ENSP000002333794) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008152metabolic process ----

    FAHD2A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FAHD2A (FAH2A)

    2 HMDB Compounds for FAHD2A    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--
    MagnesiumMagnesium (see all 2)7439-95-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for FAHD2A gene: 
    NM_016044.2  

    Unigene Clusters for FAHD2A:

    Fumarylacetoacetate hydrolase domain containing 2A
    Hs.531247  [show with all ESTs], Hs.546387  [show with all ESTs]
    Unigene Representative Sequences: AK092980, BC009403
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000445649 ENST00000447036 ENST00000233379(uc002sur.3) ENST00000418606
    ENST00000463940 ENST00000470100
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat FAHD2A using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate FAHD2A
    SwitchGear 3'UTR luciferase reporter plasmidFAHD2A 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for FAHD2A
    Predesigned siRNA for gene silencing in human, mouse, rat FAHD2A
    Clone
    Products:
         
    OriGene clones in human, mouse for FAHD2A (see all 7)
    OriGene ORF clones in mouse, rat for FAHD2A
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: FAHD2A (NM_016044)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FAHD2A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAHD2A
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for FAHD2A
    OriGene qSTAR qPCR primer pairs in human, mouse for FAHD2A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAHD2A
      QuantiTect SYBR Green Assays in human, mouse, rat FAHD2A
      QuantiFast Probe-based Assays in human, mouse, rat FAHD2A

    Additional mRNA sequence: 

    AF151863.1 BC009403.2 BC110911.1 

    14 DOTS entries:

    DT.450507  DT.305989  DT.100793815  DT.92470090  DT.120995207  DT.120995206  DT.100698654  DT.120995210 
    DT.95256227  DT.95262501  DT.99964845  DT.102830083  DT.120995280  DT.95153101 

    Selected AceView cDNA sequences (see all 180):

    BF593987 BM705567 BU734859 AA449945 AW197147 CA388768 AA766732 BX363953 
    CF529218 T47646 BM662259 BQ677692 AI422177 BF939969 AI362906 BM694922 
    BX331160 BU731716 BQ644770 CD514796 CF529093 BE857204 CD365905 Z38369 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    FAHD2A expression in normal human tissues (normalized intensities)      FAHD2A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACGTGAGTGC
    FAHD2A Expression
    About this image


    FAHD2A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 4) fully expand
     
     Brain (Nervous System)    fully expand to see all 3 entries
             Cerebral Cortex
     
     Ovary (Reproductive System)
             Oviduct
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Liver (Hepatobiliary System)
             Hepatocytes Liver Lobule
    FAHD2A Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FAHD2A Protein Expression

    SOURCE GeneReport for Unigene clusters: Hs.531247 Hs.546387
        Custom PCR Arrays for FAHD2A
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for FAHD2A
    OriGene qSTAR qPCR primer pairs in human, mouse for FAHD2A
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAHD2A
    QuantiTect SYBR Green Assays in human, mouse, rat FAHD2A
    QuantiFast Probe-based Assays in human, mouse, rat FAHD2A
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAHD2A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for FAHD2A gene from Selected species (see all 17)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fahd2a5 fumarylacetoacetate hydrolase domain containing 2A   --   2 (62.01 cM) 127436215 
    chicken
    (Gallus gallus)
    Aves FAHD2A1 fumarylacetoacetate hydrolase domain containing 2A 65.87(n)
    65.75(a)
      426684  XM_424309.4  XP_424309.4 
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.63202 Xenopus laevis transcribed sequence with moderate similarity more 75.96(n)    CD329191.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.214292 Transcribed sequence with moderate similarity to protein more 77.25(n)    CK016138.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG60281 CG6028 52.91(n)
    45.1(a)
      42589  NM_142745.4  NP_651002.3 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes FMP416
    Putative protein of unknown function; GFP-fusion p...
    28(a)
    1 → many
    XIV(318030-318809) YNL168C


    ENSEMBL Gene Tree for FAHD2A (if available)
    TreeFam Gene Tree for FAHD2A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for FAHD2A gene
    FAHD2B2  FAHD12  
    2 SIMAP similar genes for FAHD2A using alignment to 3 protein entries:     FAH2A_HUMAN (see all proteins):
    FAHD2B    FAHD1

    FAHD2A for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for FAHD2A
    PGOHUM00000239850 PGOHUM00000250467


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for FAHD2A (see all 232)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1137933771,2
    C--96066637(+) CATTGC/TGCTTG 1 -- us2k10--------
    rs1148876071,2
    F--96066706(+) TCTTTC/ATTTTT 1 -- us2k11Minor allele frequency- A:0.04NA 120
    rs1848730311,2
    --96066768(+) GATCTC/TGGCTC 1 -- us2k10--------
    rs1905687171,2
    --96067225(+) GAAACC/TCTTGT 1 -- us2k10--------
    rs1930813711,2
    --96067254(+) AATCCC/TCCTGA 1 -- us2k10--------
    rs1167527911,2
    F--96067275(+) CCCCAT/CAGGTT 1 -- us2k11Minor allele frequency- C:0.02NA 120
    rs1157861281,2
    F--96067464(+) ACCTAC/GCGAGC 1 -- us2k11Minor allele frequency- G:0.14WA 118
    rs1852348321,2
    --96067468(+) ACCGAA/GCTAGA 1 -- us2k10--------
    rs1149344451,2
    F--96067607(+) CTCAAC/ACGCAC 1 -- us2k11Minor allele frequency- A:0.01NA 120
    rs1173805981,2
    C,F--96067676(+) GTCGGG/TACATG 1 -- us2k11Minor allele frequency- T:0.03EA 120

    HapMap Linkage Disequilibrium report for FAHD2A (96068448 - 96082364 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FAHD2A:    About this table    
    Variant IDTypeSubtypePubMed ID
    dgv1228e1CNV Complex17122850
    nsv7320OTHER Inversion18451855

    Site Specific Mutation Identification with PCR Assays
    Search QIAGEN SeqTarget long-range PCR primers for resequencing FAHD2A
    DNA2.0 Custom Variant and Variant Library Synthesis for FAHD2A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    5 diseases for FAHD2A:    About MalaCards
    obesity    tuberculosis    malaria    cerebritis
    thyroiditis


    FAHD2A for disorders           About GeneDecksing

    Genetic Association Database (GAD): FAHD2A
    Human Genome Epidemiology (HuGE) Navigator: FAHD2A (1 document)

    Export disorders for FAHD2A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for FAHD2A gene, integrated from 10 sources (see all 13):
    (articles sorted by number of sources associating them with FAHD2A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Use of genome-wide expression data to mine the &quot;Gray Zone&quot; of GWA studies leads to novel candidate obesity genes. (PubMed id 20532202)1, 4 Naukkarinen J....Peltonen L. (PLoS Genet. 2010)
    2. Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics. (PubMed id 10810093)1, 2 Lai C.-H.... Lin W.-C. (Genome Res. 2000)
    3. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    4. Ubiquitin ligase substrate identification through quantitative proteomics at both the protein and peptide levels. (PubMed id 21987572)1 Lee K.A....Doedens J.R. (J. Biol. Chem. 2011)
    5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    6. Global identification of modular cullin-RING ligase substrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (Cell 2011)
    7. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
    8. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)2 Hillier L.W.... Wilson R.K. (Nature 2005)
    9. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    10. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 51011 HGNC: 24252 AceView: FAHD2A Ensembl:ENSG00000115042 euGenes: HUgn51011
    ECgene: FAHD2A H-InvDB: FAHD2A

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for FAHD2A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for FAHD2A gene:
    Search GeneIP for patents involving FAHD2A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for FAHD2A   OriGene RNAi products in human, mouse, rat for FAHD2A  
     OriGene qPCR primer pairs and template standards for FAHD2A   OriGene Protein Over-expression Lysate for FAHD2A  
     OriGene MassSpec something-or-other for FAHD2A   OriGene clones in human, mouse for FAHD2A  
     OriGene qSTAR qPCR primer pairs in human, mouse for FAHD2A   OriGene Purified Protein for FAHD2A  
     OriGene ORF clones in mouse, rat for FAHD2A   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FAHD2A   OriGene Custom Protein Services for FAHD2A  

     
     
     Block miRNA regulation of human, mouse, rat FAHD2A using miScript Target Protectors SeqTarget long-range PCR primers for resequencing FAHD2A
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FAHD2A Predesigned siRNA for gene silencing in human, mouse, rat FAHD2A
     QuantiFast Probe-based Assays in human, mouse, rat FAHD2A QuantiTect SYBR Green Assays in human, mouse, rat FAHD2A
     Custom PCR Arrays for FAHD2A Search Chromatin IP Primers for FAHD2A
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat FAHD2A  Search GeneGlobe Interaction Network for FAHD2A
     Regulatory tfbs in FAHD2A promoter
     GenScript Custom Purified and Recombinant Proteins Services for FAHD2A GenScript cDNA clones with any tag delivered in your preferred vector for FAHD2A
     GenScript Custom Assay Services for FAHD2A GenScript Custom overexpressing Cell Line Services for FAHD2A
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for FAHD2A (FAH2A)
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     cDNA Clones for FAHD2A
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     FAHD2A antibodies
     FAHD2A proteins
     FAHD2A lysates
     Antibodies for FAHD2A
     See all of Abcam's Antibodies, Kits and Proteins for FAHD2A
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for FAHD2A
     Antibodies for FAHD2A
     ELISAs for FAHD2A
     CLIAs for FAHD2A



     Browse ESI BIO Cell Lines and PureStem Progenitors for FAHD2A
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FAHD2A
     SwitchGear 3'UTR luciferase reporter plasmids for FAHD2A
     SwitchGear Promoter luciferase reporter plasmids for FAHD2A
     ThermoFisher Antibodies for FAHD2A
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FAHD2A
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FAHD2A
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for FAHD2A
     LSBio Antibodies in human, mouse, rat for FAHD2A
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      FAHD2A gene at Home site.
    Version: 3.12.136 22 July 2014
    hostname: 356980-web2.xennexinc.com index build: 126 solr: 1.4