Aliases for FAF2 Gene
External Ids for FAF2 Gene
Previous Symbols for FAF2 Gene
The protein encoded by this gene is highly expressed in peripheral blood of patients with atopic dermatitis (AD), compared to normal individuals. It may play a role in regulating the resistance to apoptosis that is observed in T cells and eosinophils of AD patients. [provided by RefSeq, Jul 2008]
GeneCards Summary for FAF2 Gene
FAF2 (Fas Associated Factor Family Member 2) is a Protein Coding gene. Diseases associated with FAF2 include atopic dermatitis and enophthalmos. GO annotations related to this gene include ubiquitin protein ligase binding and ubiquitin binding. An important paralog of this gene is FAF1.
UniProtKB/Swiss-Prot for FAF2 Gene
May play a role in the translocation of terminally misfolded proteins from the endoplasmic reticulum lumen to the cytoplasm and their degradation by the proteasome.