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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FABP7 Gene

protein-coding   GIFtS: 61
GCID: GC06P123142

Fatty Acid Binding Protein 7, Brain

Alzheimer's & Parkinson's Diseases Congress
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Fatty Acid Binding Protein 7, Brain1 2     Fatty Acid-Binding Protein 72 3
BLBP2 3 5     Mammary-Derived Growth Inhibitor Related2 3
FABPB2 3 5     B-FABP2 3
Brain Lipid Binding Protein1 2     MRG2 3
Brain Lipid-Binding Protein2 3     Fatty Acid-Binding Protein, Brain2
Brain-Type Fatty Acid-Binding Protein2 3     Mammary-Derived Growth Inhibitor-Related2

External Ids:    HGNC: 35621   Entrez Gene: 21732   Ensembl: ENSG000001644347   OMIM: 6029655   UniProtKB: O155403   

Export aliases for FABP7 gene to outside databases

Previous GC identifers: GC06P122871 GC06P123058 GC06P123035 GC06P123081 GC06P120677


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FABP7 Gene:
The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a
family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic
ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. (provided by RefSeq,
Jul 2008)

GeneCards Summary for FABP7 Gene: 
FABP7 (fatty acid binding protein 7, brain) is a protein-coding gene. Diseases associated with FABP7 include optic nerve glioma, and chiasmal syndrome. GO annotations related to this gene include lipid binding and transporter activity. An important paralog of this gene is FABP5.

UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540
Function: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential
morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber
system in developing brain, a system that is necessary for the migration of immature neurons to establish
cortical layers (By similarity)

Gene Wiki entry for FABP7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NT_025741.15  NC_018917.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FABP7 gene promoter:
         TBP   USF1   NF-1   HOXA3   HNF-4alpha1   Evi-1   Egr-4   USF-1   STAT3   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFABP7 promoter sequence
   Search SABiosciences Chromatin IP Primers for FABP7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FABP7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q22-q23   Ensembl cytogenetic band:  6q22.31   HGNC cytogenetic band: 6q22-q23

FABP7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FABP7 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P123142:  view genomic region     (about GC identifiers)

Start:
123,100,620 bp from pter      End:
123,105,219 bp from pter
Size:
4,600 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540 (See protein sequence)
Recommended Name: Fatty acid-binding protein, brain  
Size: 132 amino acids; 14889 Da
Subcellular location: Cytoplasm
3 PDB 3D structures from and Proteopedia for FABP7:
1FDQ (3D)        1FE3 (3D)        1JJX (3D)    
Secondary accessions: B2R4L1 O14951 Q6IAU7

Explore the universe of human proteins at neXtProt for FABP7: NX_O15540

Explore proteomics data for FABP7 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_O15540

  • FABP7 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FABP7 Protein Expression
    REFSEQ proteins: NP_001437.1  
    ENSEMBL proteins: 
     ENSP00000357429   ENSP00000348931  

    Human Recombinant Protein Products for FABP7: 
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    Sino Biological Recombinant Protein for FABP7
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    ProSpec Recombinant Protein for FABP7
    Cloud-Clone Corp. Proteins for FABP7 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0042995cell projection IEA--
    GO:0043025neuronal cell body IEA--

    FABP7 for ontologies           About GeneDecksing



    FABP7 Antibody Products: 
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    FABP: Fatty acid binding protein family

    4 InterPro protein domains:
     IPR012674 Calycin
     IPR011038 Calycin-like
     IPR000463 Fatty_acid-bd
     IPR000566 Lipocln_cytosolic_FA-bd_dom

    Graphical View of Domain Structure for InterPro Entry O15540

    ProtoNet protein and cluster: O15540

    1 Blocks protein domain: IPB000463 Cytosolic fatty-acid binding protein

    UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540
    Domain: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior
    Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family


    FABP7 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FABP7_HUMAN, O15540
    Function: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential
    morphogenic activity during CNS development. It is required for the establishment of the radial glial fiber
    system in developing brain, a system that is necessary for the migration of immature neurons to establish
    cortical layers (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0008289lipid binding IEA--
         
    FABP7 for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Fabp7):
     behavior/neurological  homeostasis/metabolism  nervous system  no phenotypic analysis 

    FABP7 for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for FABP7 
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    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP7


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for FABP7 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Transcription factors in neurogenesis
    Transcription factors in neurogenesis
    2PPAR signaling pathway
    PPAR signaling pathway
    3Neuroscience
    Neuroscience

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 EMD Millipore Pathway for FABP7
        Transcription factors in neurogenesis


    1 Cell Signaling Technology (CST) Pathway for FABP7
        Neuroscience



    1         Kegg Pathway  (Kegg details for FABP7):
        PPAR signaling pathway


    FABP7 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FABP7

    2 Interacting proteins for FABP7 (O155403) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DYNLT1P631723I2D: score=2 
    KBTBD7Q8WVZ93I2D: score=1 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001964startle response ----
    GO:0007399nervous system development TAS9375786
    GO:0008285negative regulation of cell proliferation TAS9250612
    GO:0021846cell proliferation in forebrain IEA--
    GO:0022008neurogenesis IEA--

    FABP7 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FABP7 for compounds           About GeneDecksing

    EMD Millipore small molecules for FABP7:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FABP7

    5 DrugBank Compounds for FABP7    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Docosa-4,7,10,13,16,19-Hexaenoic Acid-- --carrier--17139284 17016423
    IcosapentEicosapentaenoic acid (see all 4)10417-94-4carrier--17547694 10854433
    Oleic Acid-- 112-80-1carrier--17139284 17016423
    gamma-Homolinolenic acid(Z,Z,Z)-8,11,14-Eicosatrienoic acid (see all 6)1783-84-2carrier--17139284 17016423
    Alpha-Linolenic Acid(9Z,12Z,15Z)-Octadecatrienoic acid (see all 5)463-40-1carrier--10854433

    8 Novoseek inferred chemical compound relationships for FABP7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fatty acid 57.1 22 12479569 (2), 18826602 (2), 19608352 (2), 18391847 (2) (see all 17)
    docosahexaenoic acid 44.8 12 10854433 (3), 8798739 (2), 11103817 (2)
    lipid 30.4 21 12612091 (2), 15622533 (1), 18593473 (1), 18826602 (1) (see all 14)
    oleic acid 19.5 4 8798739 (1), 10854433 (1)
    retinoic acid 15.9 1 8798739 (1)
    arachidonic acid 1.01 3 8798739 (1), 10854433 (1)
    gaba 0.24 2 17711980 (1), 17152062 (1)
    glutamate 0 4 18629509 (1), 17711980 (1), 14550780 (1), 17152062 (1)

    Search CenterWatch for drugs/clinical trials and news about FABP7

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FABP7 gene: 
    NM_001446.3  

    Unigene Cluster for FABP7:

    Fatty acid binding protein 7, brain
    Hs.26770  [show with all ESTs]
    Unigene Representative Sequence: AB208815
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368444(uc003pzf.3) ENST00000356535(uc003pzd.3 uc003pze.1)


    miRNA
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    Additional mRNA sequence: 

    AB208815.1 AJ002962.1 AK289836.1 AK307272.1 AK311867.1 AL512688.1 BC012299.1 CR457057.1 
    D50373.1 D88648.1 U51338.1 U81235.1 

    5 DOTS entries:

    DT.313655  DT.40110554  DT.91736342  DT.91744417  DT.121347539 

    24/104 AceView cDNA sequences (see all 104):

    AW162191 BX461253 AI929340 AW157160 AW163440 BX113553 BM698823 AI878887 
    AW163515 AI929618 D88648 NM_001446 BM668866 AL512688 AV718267 AI879439 
    BC012299 AK091664 BI544779 BM669606 AW160409 AI652178 U51338 BE894943 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FABP7 expression in normal human tissues (normalized intensities)      FABP7 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTATAATT
    FABP7 Expression
    About this image


    FABP7 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/14 selected tissues (see all 14) fully expand
     
     Brain (Nervous System)    fully expand to see all 27 entries
             Choroid Plexus Progenitor Cells Choroid Plexus
             Thalamus
             bFGF induced cells ( Generation of motor and gamma-aminobutyric acid (GABA) neurons...
             Human Cerebellar Astrocytes   
             Olfactory Bulb   
     
     Neural Tube (Nervous System)    fully expand to see all 9 entries
             Telencephalon
             spinal cord/lateral wall/ventricular layer   
     
     Spinal Cord (Nervous System)    fully expand to see all 5 entries
             Dorsal Root Ganglion   
     
     Eye (Sensory Organs)    fully expand to see all 4 entries
             nGnG Amacrine Cells Inner Nuclear Layer
             Retina
             Human Non-Pigment Ciliary Epithelial Cells (HNPCEpiC)   
     
     Peripheral Nervous System (Nervous System)    fully expand to see all 3 entries
             Immature Schwann Cells Peripheral Nerve Domain
             spinal/ganglion/dorsal root ganglion   

    See FABP7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FABP7

    SOURCE GeneReport for Unigene cluster: Hs.26770

    UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540
    Tissue specificity: Expressed in brain and other neural tissues

        SABiosciences Expression via Pathway-Focused PCR Arrays including FABP7: 
              Notch Signaling Targets in human mouse rat
              Fatty Acid Metabolism in human mouse rat
              Cell Lineage Identification in human mouse rat
              PPAR Targets in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP7

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for FABP7 gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fabp71 , 5 fatty acid binding protein 7, brain1, 5 85.35(n)1
    87.12(a)1
      10 (29.25 cM)5
    121401  NM_021272.31  NP_067247.11 
     577848815 
    chicken
    (Gallus gallus)
    Aves FABP71 fatty acid binding protein 7, brain 81.31(n)
    91.67(a)
      396246  NM_205308.2  NP_990639.1 
    lizard
    (Anolis carolinensis)
    Reptilia FABP76
    Uncharacterized protein
    91(a)
    1 ↔ 1
    1(182269043-182277716)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.158142 Xenopus laevis transcribed sequence with weak similarity more 72.83(n)    BJ084106.1 
    zebrafish
    (Danio rerio)
    Actinopterygii fabp72 fatty acid binding protein 7, brain 77.59(n)   58128  BC055621.1 


    ENSEMBL Gene Tree for FABP7 (if available)
    TreeFam Gene Tree for FABP7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FABP7 gene
    FABP52  RBP52  FABP92  CRABP22  FABP122  FABP42  FABP32  RBP12  
    RBP22  CRABP12  FABP22  PMP22  RBP72  
    15 SIMAP similar genes for FABP7 using alignment to 1 protein entry:     FABP7_HUMAN:
    DKFZp547J2313    FABP3    FABP4    FABP9    PMP2    FABP5
    FABP12    FABP5P3    RBP5    CRABP2    CRABP1    RBP1
    FABP2    RBP7    RBP2

    FABP7 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for FABP7
    PGOHUM00000244522 PGOHUM00000240200


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/187 SNPs in FABP7 are shown (see all 187)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs785181321,2
    C,F--123098727(+) GGTAAT/CGCAAG 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1851606031,2
    --123098865(+) GGTACA/GTGTCT 1 -- us2k10--------
    rs751070031,2
    C,F--123098871(+) TGTCTG/ATTGTC 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs122059681,2
    C,F--123098981(+) agaccC/Ttttct 1 -- us2k1 trp36Minor allele frequency- T:0.11NA WA EA 364
    rs1504076081,2
    C--123098990(+) TCCAA-/AAATAAATAAAT/
    AAATAAATAAATAAAT
    AAATA
    2 -- us2k1 cds10--------
    rs1470441001,2
    --123099157(+) ACCAAC/TGTATG 1 -- us2k10--------
    rs77692371,2
    A--123099162(+) tgtatG/Tccttc 1 -- us2k10--------
    rs77690991,2
    A--123099182(+) atttaC/Tgtttt 1 -- us2k1 tfbs30--------
    rs1903545121,2
    --123099261(+) TCCCAA/TGGCTT 1 -- us2k10--------
    rs77692611,2
    A--123099301(+) ttgctC/Tatatt 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FABP7 (123100620 - 123105219 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for FABP7:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv886601CNV Gain21882294
    nsv830791CNV Gain17160897


    Human Gene Mutation Database (HGMD): FABP7
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing FABP7
    DNA2.0 Custom Variant and Variant Library Synthesis for FABP7

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 602965    OMIM disorders: --

    20/25 diseases for FABP7 (see all 25):    About MalaCards
    optic nerve glioma    chiasmal syndrome    head injury    malignant glioma
    subependymal giant cell astrocytoma    oligoastrocytoma    cutaneous malignant melanoma    meningioma
    oligodendroglioma    neurofibromatosis    astrocytoma    down syndrome
    bipolar disorder    renal cell carcinoma    glioblastoma    melanoma
    multiple sclerosis    schizophrenia    dementia    breast cancer


    FABP7 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    6 Novoseek inferred disease relationships for FABP7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    malignant glioma 45.2 25 10896661 (6), 17898869 (4), 19540848 (4), 9591779 (3)
    carcinoma renal cell 18 5 17083565 (2), 19622156 (2), 17320655 (1)
    tumors 16.4 15 19622156 (3), 11103817 (2), 17898869 (2), 17083565 (2) (see all 10)
    breast cancer 8.7 12 9242429 (4), 11103817 (2), 9731516 (1), 19608352 (1)
    breast carcinoma 5.16 2 9242429 (2)
    hyperplasia 0 1 9242429 (1)

    Genetic Association Database (GAD): FABP7
    Human Genome Epidemiology (HuGE) Navigator: FABP7 (2 documents)

    Export disorders for FABP7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FABP7 gene, integrated from 9 sources (see all 101):
    (articles sorted by number of sources associating them with FABP7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein. (PubMed id 10854433)1, 2, 7, 9 Balendiran G.K.... Sacchettini J.C. (2000)
    2. Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). (PubMed id 9375786)1, 2, 3, 9 Shimizu F.... Fujiwara T. (1997)
    3. Correlation of B-FABP and GFAP expression in malignant glioma. (PubMed id 9591779)1, 2, 9 Godbout R.... Day R.S. III (1998)
    4. Solution structure of fatty acid-binding protein from human brain. (PubMed id 12479569)1, 2, 9 Rademacher M....Luecke C. (2002)
    5. Association analyses between brain-expressed fatty-ac id binding protein (FABP) genes and schizophrenia and bipolar disorder. (PubMed id 19554614)1, 4, 9 Iwayama Y....Yoshikawa T. (2010)
    6. Polymorphism screening of brain-expressed FABP7, 5 an d 3 genes and association studies in autism and schizophrenia in Japanese subje cts. (PubMed id 20057506)1, 4 Maekawa M....Yoshikawa T. (2010)
    7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    9. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    10. Ligand specificity of brain lipid-binding protein. (PubMed id 8798739)1, 9 Xu L.Z....Heintz N. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2173 HGNC: 3562 AceView: FABP7 Ensembl:ENSG00000164434 euGenes: HUgn2173
    ECgene: FABP7 Kegg: 2173 H-InvDB: FABP7

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FABP7 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FABP7 gene:
    Search GeneIP for patents involving FABP7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    About This Section

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