Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FABP7 Gene

protein-coding   GIFtS: 59
GCID: GC06P123142

fatty acid binding protein 7, brain
 Explore 29 diseases affiliated with
FABP7 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for FABP7    

Aliases
for FABP7 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Fatty Acid Binding Protein 7, Brain1 2     Fatty Acid-Binding Protein 72 3
BLBP1 2 3 5     Mammary-Derived Growth Inhibitor Related2 3
B-FABP1 2 3     MRG2 3
FABPB2 3 5     Brain Lipid Binding Protein2
Brain Lipid-Binding Protein2 3     Fatty Acid-Binding Protein, Brain2
Brain-Type Fatty Acid-Binding Protein2 3     Mammary-Derived Growth Inhibitor-Related2

External Ids:    HGNC: 35621   Entrez Gene: 21732   Ensembl: ENSG000001644347   OMIM: 6029655   UniProtKB: O155403   

Export aliases for FABP7 gene to outside databases

Previous GC identifers: GC06P122871 GC06P123058 GC06P123035 GC06P123081 GC06P120677


Summaries
for FABP7 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for FABP7:
The protein encoded by this gene is a brain fatty acid binding protein. Fatty acid binding proteins (FABPs) are a
family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic
ligands. FABPs are thought to play roles in fatty acid uptake, transport, and metabolism. (provided by RefSeq, Jul
2008)

UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540
Function: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic
activity during CNS development. It is required for the establishment of the radial glial fiber system in developing
brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity)

Gene Wiki entry for FABP7


Genomic Views
for FABP7 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.1  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FABP7 gene promoter:
         TBP   USF1   NF-1   HOXA3   HNF-4alpha1   Evi-1   Egr-4   USF-1   STAT3   Cart-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: FABP7 promoter sequence
   Search SABiosciences Chromatin IP Primers for FABP7

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FABP7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q22-q23   Ensembl cytogenetic band:  6q22.31   HGNC cytogenetic band: 6q22-q23

FABP7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FABP7 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P123142:  view genomic region     (about GC identifiers)

Start:
 123,100,620 bp from pter      End:
 123,105,219 bp from pter
Size:
 4,600 bases      Orientation:
 plus strand

Proteins
for FABP7 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540 (See protein sequence)
Recommended Name: Fatty acid-binding protein, brain  
Size: 132 amino acids; 14889 Da
Subcellular location: Cytoplasm
3 PDB 3D structures from and Proteopedia for FABP7:
1FDQ (3D)        1FE3 (3D)        1JJX (3D)    
Secondary accessions: B2R4L1 O14951 Q6IAU7

Explore the universe of human proteins at neXtProt for FABP7: NX_O15540

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_O15540

    • FABP7 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_001437.1  
    ENSEMBL proteins: 
     ENSP00000357429   ENSP00000348931  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    OriGene Purified Protein: FABP7
    OriGene Protein Over-expression Lysate: FABP7
    OriGene Custom Protein Services for FABP7 
    GenScript Custom Purified and Recombinant Proteins Services for FABP7
    Novus Biologicals FABP7 Proteins
    Novus Biologicals FABP7 Lysates
    Browse Sino Biological Recombinant Proteins
    ProSpec Recombinant Protein for FABP7
    Uscn Proteins for FABP7

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0042995cell projection IEA--
    GO:0043025neuronal cell body IEA--


    FABP7 for ontologies           About GeneDecksing



    FABP7 Antibody Products: 
    EMD Millipore Mono- and Polyclonal Antibodies for the study of FABP7
    R&D Systems Antibodies for FABP7 (FABP7/B-FABP)
    Cell Signaling Technology (CST) Antibodies for FABP7 
    OriGene Antibodies (see all 2): FABP7
    OriGene Custom Antibody Services for FABP7 
    GenScript Superior Antibodies for FABP7
    Novus Biologicals FABP7 Antibodies
    Abcam antibodies for FABP7 
    Uscn Antibodies for FABP7
    ThermoFisher Antibodies for FABP7

    Assay Products for FABP7: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for FABP7
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for FABP7

    Protein Domains /
    Families
    for FABP7 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    FABP7 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR012674 Calycin
     IPR011038 Calycin-like
     IPR000463 Fatty_acid-bd
     IPR000566 Lipocln_cytosolic_FA-bd_dom

    Graphical View of Domain Structure for InterPro Entry O15540

    ProtoNet protein and cluster: O15540

    1 Blocks protein family: IPB000463 Cytosolic fatty-acid binding protein

    UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540
    Domain: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior
    Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family


    Function
    for FABP7 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540
    Function: B-FABP could be involved in the transport of a so far unknown hydrophobic ligand with potential morphogenic
    activity during CNS development. It is required for the establishment of the radial glial fiber system in developing
    brain, a system that is necessary for the migration of immature neurons to establish cortical layers (By similarity)

    miRNA
    Products:            		 OriGene 3'-UTR Clone: FABP7
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FABP7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FABP7
    SwitchGear 3'UTR luciferase reporter plasmid: FABP7 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FABP7 (see all 6)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FABP7

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for FABP7

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FABP7 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FABP7
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: FABP7 (NM_001446)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FABP7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FABP7 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for FABP7
    Search LifeMap BioReagents cell lines for FABP7

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP7

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0008289lipid binding IEA--


    FABP7 for ontologies           About GeneDecksing


    Animal Models:
         4 MGI mutant phenotypes (inferred from 3 alleles) (MGI details for Fabp7):
     behavior/neurological  homeostasis/metabolism  nervous system  no phenotypic analysis 

    FABP7 for phenotypes           About GeneDecksing


    Pathways & Interactions
    for FABP7 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Transcription factors in neurogenesis
    		Transcription factors in neurogenesis1.00
    2PPAR signaling pathway
    		PPAR signaling pathway1.00
    3Neuroscience
    		Neuroscience1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways

    1 EMD Millipore Pathway for FABP7
        Transcription factors in neurogenesis


    1 Cell Signaling Technology (CST) Pathway for FABP7
        Neuroscience


    1         Kegg Pathway  (Kegg details for FABP7):
        PPAR signaling pathway


    FABP7 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FABP7

    2 Interacting proteins for FABP7 (O155403) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DYNLT1P631723I2D: score=2 
    KBTBD7Q8WVZ93I2D: score=1 
    About this table

    Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001964startle response ----
    GO:0007399nervous system development TAS9375786
    GO:0008285negative regulation of cell proliferation TAS9250612
    GO:0021846cell proliferation in forebrain IEA--
    GO:0022008neurogenesis IEA--


    FABP7 for ontologies           About GeneDecksing



    Drugs & Compounds
    for FABP7 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FABP7 for compounds           About GeneDecksing

    EMD Millipore small molecules for FABP7:
    Small Molecule - inhibitor
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for FABP7

    5 DrugBank Compounds for FABP7    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Docosa-4,7,10,13,16,19-Hexaenoic Acid-- --carrier--17139284 17016423
    IcosapentEicosapentaenoic acid (see all 4)10417-94-4carrier--17547694 10854433
    Oleic Acid-- 112-80-1carrier--17139284 17016423
    gamma-Homolinolenic acid(8E,11E,14E)-8,11,14-Icosatrienoic acid (see all 7)1783-84-2carrier--17139284 17016423
    Alpha-Linolenic Acid(9Z,12Z,15Z)-Octadecatrienoic acid (see all 5)463-40-1carrier--10854433

    8 Novoseek chemical compound relationships for FABP7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fatty acid 57.1 22 12479569 (2), 18826602 (2), 19608352 (2), 18391847 (2) (see all 17)
    docosahexaenoic acid 44.8 12 10854433 (3), 8798739 (2), 11103817 (2)
    lipid 30.4 21 12612091 (2), 15622533 (1), 18593473 (1), 18826602 (1) (see all 14)
    oleic acid 19.5 4 8798739 (1), 10854433 (1)
    retinoic acid 15.9 1 8798739 (1)
    arachidonic acid 1.01 3 8798739 (1), 10854433 (1)
    gaba 0.24 2 17711980 (1), 17152062 (1)
    glutamate 0 4 18629509 (1), 17711980 (1), 14550780 (1), 17152062 (1)

    Search CenterWatch for drugs/clinical trials and news about FABP7 

    Transcripts
    for FABP7 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for FABP7 gene: 
    NM_001446.3  

    Unigene Cluster for FABP7:

    Fatty acid binding protein 7, brain
    Hs.26770  [show with all ESTs]
    Unigene Representative Sequence: AB208815
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000368444(uc003pzf.3) ENST00000356535(uc003pzd.3 uc003pze.1)


    miRNA
    Products:             		 OriGene 3'-UTR Clone: FABP7
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat FABP7
    Search QIAGEN for miScript miRNA Assays for microRNAs that regulate FABP7
    SwitchGear 3'UTR luciferase reporter plasmid: FABP7 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FABP7 (see all 6)
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FABP7
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FABP7 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FABP7
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: FABP7 (NM_001446)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for FABP7
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FABP7 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FABP7
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FABP7
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FABP7
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FABP7

    Additional cDNA sequence: 

    AB208815.1 AJ002962.1 AK289836.1 AK307272.1 AK311867.1 AL512688.1 BC012299.1 CR457057.1 
    D50373.1 D88648.1 U51338.1 U81235.1 

    5 DOTS entries:

    DT.313655  DT.40110554  DT.91736342  DT.91744417  DT.121347539 

    24/104 AceView cDNA sequences (see all 104):

    AW163515 AL512688 AI929340 AI879439 AW157160 D88648 AW163440 BX113553 
    NM_001446 AW162191 BM698823 AI929618 AV718267 BM668866 AI878887 BX461253 
    BU736791 AI962699 U81235 CR457057 AI364541 BI860090 AW156936 W72051 

    GeneLoc Exon Structure


    Expression
    for FABP7 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FABP7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TTTTATAATT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    FABP7 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    8 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    BrainBlood Brain BarrierEndothelial CellsBlood Brain Barrier, Endothelium
    BrainBlood Brain BarrierPostnatal Endothelial CellsBlood Brain Barrier, Endothelium
    HeartMyocardiumCardiac FibroblastsEpicardium
    OvaryAntral FollicleCumulus CellsOvary
    BrainHypothalamusBrain
    BrainMedulla OblongataBrain
    Neural TubeMetencephalonNeural Tube
    Neural TubeTelencephalonNeural Tube
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 2 LifeMap Cells 
    NameCategory
    bFGF induced cells (Generation of motor ...)
    N2/LSB/S/F8-induced cells (Generation of midbra...)

    See FABP7 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FABP7

    SOURCE GeneReport for Unigene cluster: Hs.26770

    UniProtKB/Swiss-Prot: FABP7_HUMAN, O15540
    Tissue specificity: Expressed in brain and other neural tissues

        SABiosciences Expression via Pathway-Focused PCR Arrays including FABP7: 
              Notch Signaling Targets in human mouse rat
              Fatty Acid Metabolism in human mouse rat
              Cell Lineage Identification in human mouse rat
              PPAR Targets in human mouse rat

    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FABP7
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat FABP7
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FABP7
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FABP7
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP7

    Orthologs
    for FABP7 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for FABP7 gene from 6/19 species (see all 19)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    chicken
    (Gallus gallus)    		 Aves FABP71 fatty acid binding protein 7, brain 81.31(n)
    91.67(a)    		   396246  NM_205308.2  NP_990639.1 
    lizard
    (Anolis carolinensis)    		 Reptilia FABP76
    		 --
    		 91(a)
    		 1 ↔ 1
    		 1(182271190-182277366)
    African clawed frog
    (Xenopus laevis)    		 Amphibia Xl.158142 Xenopus laevis transcribed sequence with weak similarity more 72.83(n)    BJ084106.1 
    zebrafish
    (Danio rerio)    		 Actinopterygii fabp72 fatty acid binding protein 7, brain 77.59(n)   58128  BC055621.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta fabp6
    		 fatty acid bindin protein
    		 37(a)
    		 possible ortholog
    		 3R(7385612-7392771)
    worm
    (Caenorhabditis elegans)    		 Secernentea lbp-66
    lbp-56
    (see all 5)    		 Fatty acid-binding protein homolog 5
    (see all 5)    		 45(a)
    39(a)
    (see all 5)    		 many ↔ many
    many ↔ many
    (see all 5)    		 I(6728286-6729379)
    I(6731270-6732281)


    ENSEMBL Gene Tree for FABP7 (if available)
    TreeFam Gene Tree for FABP7 (if available) 

    Paralogs
    for FABP7 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FABP7 gene
    FABP52  RBP52  FABP92  CRABP22  FABP122  FABP42  RBP12  FABP32  
    CRABP12  RBP22  FABP22  PMP22  RBP72  
    15 SIMAP similar genes for FABP7 using alignment to 1 protein entry:     FABP7_HUMAN:
    DKFZp547J2313    FABP3    FABP4    FABP9    PMP2    FABP5
    FABP12    FABP5P3    RBP5    CRABP2    CRABP1    RBP1
    FABP2    RBP7    RBP2

    FABP7 for paralogs           About GeneDecksing


    2 Pseudogenes.org Pseudogenes for FABP7
    PGOHUM00000244522 PGOHUM00000240200


    Genomic Variants
    for FABP7 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/159 NCBI SNPs in FABP7 are shown (see all 159)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 6 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs785181321,2
    		F,--123098727(+) GGTAAT/CGCAAG 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1851606031,2
    		--123098865(+) GGTACA/GTGTCT 1 -- us2k10--------
    rs751070031,2
    		--123098871(+) TGTCTG/ATTGTC 1 -- us2k11Minor allele frequency- A:0.01WA 118
    rs122059681,2
    		C,F,--123098981(+) AGACCC/TTTTCT 1 -- us2k1 trp36Minor allele frequency- T:0.11NA WA EA 364
    rs1504076081,2
    		--123098990(+) TCCAA-/AAATAAA
    TAAATAAAT    AAATA     		1 -- us2k10--------
    rs1470441001,2
    		--123099157(+) ACCAAC/TGTATG 1 -- us2k10--------
    rs77692371,2
    		A--123099162(+) tgtatG/Tccttc 1 -- us2k10--------
    rs77690991,2
    		A--123099182(+) atttaC/Tgtttt 1 -- us2k1 tfbs30--------
    rs1903545121,2
    		--123099261(+) TCCCAA/TGGCTT 1 -- us2k10--------
    rs77692611,2
    		A--123099301(+) ttgctC/Tatatt 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FABP7 (123100620 - 123105219 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FABP7: --
    Human Gene Mutation Database (HGMD): FABP7

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FABP7
    DNA2.0 Custom Variant and Variant Library Synthesis for FABP7

    Disorders / Diseases
    for FABP7 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    FABP7 for disorders           About GeneDecksing

    OMIM gene information: 602965    OMIM disorders: --

    20/29 diseases for FABP7 (see all 29):    About MalaCards
    subependymal giant cell astrocytoma    optic nerve glioma    chiasmal syndrome    cutaneous malignant melanoma
    atrial fibrillation    malignant glioma    oligoastrocytoma    anaplastic meningioma
    head injury    renal cell carcinoma    bipolar disorder    down syndrome
    multiple sclerosis    oligodendroglioma    meningioma    neurofibromatosis
    breast carcinoma    astrocytoma    breast cancer    renal carcinoma

    6 Novoseek disease relationships for FABP7 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    malignant glioma 45.2 25 10896661 (6), 17898869 (4), 19540848 (4), 9591779 (3)
    carcinoma renal cell 18 5 17083565 (2), 19622156 (2), 17320655 (1)
    tumors 16.4 15 19622156 (3), 11103817 (2), 17898869 (2), 17083565 (2) (see all 10)
    breast cancer 8.7 12 9242429 (4), 11103817 (2), 9731516 (1), 19608352 (1)
    breast carcinoma 5.16 2 9242429 (2)
    hyperplasia 0 1 9242429 (1)

    Human Genome Epidemiology (HuGE) Navigator: FABP7 (2 documents)

    Export disorders for FABP7 gene to outside databases

    Publications
    for FABP7 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FABP7 gene, integrated from 9 sources (see all 99):
    (articles sorted by number of sources associating them with FABP7)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. Crystal structure and thermodynamic analysis of human brain fatty acid-binding protein. (PubMed id 10854433)1, 2, 7, 9 Balendiran G.K.... Sacchettini J.C. (2000)
    2. Isolation and expression of a cDNA for human brain fatty acid-binding protein (B-FABP). (PubMed id 9375786)1, 2, 3, 9 Shimizu F.... Fujiwara T. (1997)
    3. Correlation of B-FABP and GFAP expression in malignant glioma. (PubMed id 9591779)1, 2, 9 Godbout R.... Day R.S. III (1998)
    4. Solution structure of fatty acid-binding protein from human brain. (PubMed id 12479569)1, 2, 9 Rademacher M....Luecke C. (2002)
    5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    7. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
    8. Ligand specificity of brain lipid-binding protein. (PubMed id 8798739)1, 9 Xu L.Z....Heintz N. (1996)
    9. Brain lipid binding protein in axon-Schwann cell interactions and peripheral nerve tumorigenesis. (PubMed id 12612091)1, 9 Miller S.J....Ratner N. (2003)
    10. Antitumor activity of the novel human breast cancer growth inhibitor, mammary-derived growth inhibitor-related gene, MRG. (PubMed id 9242429)1, 9 Shi Y.E....Gentz R. (1997)

    External Searches for FABP7 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing FABP7 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2173 HGNC: 3562 AceView: FABP7 Ensembl:ENSG00000164434 euGenes: HUgn2173
    ECgene: FABP7 Kegg: 2173 H-InvDB: FABP7

    Other Databases showing FABP7 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing FABP7 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FABP7 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for FABP7 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for FABP7 gene:
    Search GeneIP for patents involving FABP7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for FABP7 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     Browse Purified and Recombinant Proteins at EMD Millipore
     Browse for Gene Knock-down Tools from EMD Millipore
     EMD Millipore Mono- and Polyclonal Antibodies for the study of FABP7
     Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
     EMD Millipore small molecules (inhibitor) for FABP7
     Browse Kits and Assays available from EMD Millipore
     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Antibodies for FABP7 (FABP7/B-FABP)   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     OriGene Antibodies for FABP7   Browse OriGene shRNA RFPs  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for FABP7   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for FABP7  
     OriGene Protein Over-expression Lysate for FABP7   Browse OriGene Fluorogenic Cell Assay Kits  
     Browse OriGene siRNAs   OriGene 3'-UTR Clone for FABP7  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for FABP7   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for FABP7  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     OriGene Purified Protein for FABP7   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for FABP7   OriGene Custom Protein Services for FABP7  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat FABP7
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing FABP7
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FABP7
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat FABP7
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat FABP7
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat FABP7
     GenScript Custom Purified and Recombinant Proteins Services for FABP7 GenScript cDNA clones with any tag delivered in your preferred vector for FABP7
     GenScript Custom Assay Services for FABP7 GenScript Superior Antibodies for FABP7
     GenScript Custom overexpressing Cell Line Services for FABP7 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Antibodies & Assays for FABP7 

     Regulatory tfbs in FABP7 promoter
     Search Chromatin IP Primers for FABP7
     RT2 qPCR Primer Assay in human, mouse, rat FABP7
     GNC Network for FABP7
     SABiosciences PCR Arrays including human, mouse, rat FABP7
     Search Tocris compounds for FABP7
     Browse Sino Biological Proteins and Antibodies
     Browse Sino Biological cDNA Clones
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     FABP7 antibodies
     FABP7 proteins
     FABP7 lysates
     Antibodies for FABP7
     See all of Abcam's Antibodies, Kits and Proteins for FABP7
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Recombinant Protein for FABP7




     FABP7 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for FABP7
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP7
     SwitchGear 3'UTR luciferase reporter plasmids for FABP7
     SwitchGear Promoter luciferase reporter plasmids for FABP7
     ThermoFisher Antibodies for FABP7
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat FABP7
           
    GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 27 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      FABP7 gene at Home site.
    hostname: 356980-web2.xennexinc.com index build: 100 solr: 1.4