Aliases for FABP6 Gene
External Ids for FABP6 Gene
Previous GeneCards Identifiers for FABP6 Gene
This gene encodes the ileal fatty acid binding protein. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABP6 and FABP1 (the liver fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. Transcript variants generated by alternate transcription promoters and/or alternate splicing have been found for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for FABP6 Gene
FABP6 (Fatty Acid Binding Protein 6, Ileal) is a Protein Coding gene. Diseases associated with FABP6 include colorectal adenocarcinoma and glanzmann thrombasthenia. Among its related pathways are Metabolism and PPAR signaling pathway. GO annotations related to this gene include transporter activity and lipid binding. An important paralog of this gene is FABP1.
UniProtKB/Swiss-Prot for FABP6 Gene
Ileal protein which stimulates gastric acid and pepsinogen secretion. Seems to be able to bind to bile salts and bilirubins. Isoform 2 is essential for the survival of colon cancer cells to bile acid-induced apoptosis.