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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FABP5P3 Gene

pseudogene   GIFtS: 26
GCID: GC07P152137

Fatty Acid Binding Protein 5 Pseudogene 3

(Previous names: fatty acid binding protein 5-like 3, fatty acid binding...)
(Previous symbol: FABP5L3)
  Search for FABP5P3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 5.2

Aliases
Fatty Acid Binding Protein 5 Pseudogene 31 2
FABP5L31 2 3
Fatty Acid Binding Protein 5-Like 31
Fatty Acid Binding Protein 5-Like 3 (Pseudogene)1
Fatty Acid-Binding Protein 5 Pseudogene 33

External Ids:    HGNC: 225731   Entrez Gene: 2208322   Ensembl: ENSG000002417357   UniProtKB: A8MUU13   
ORGUL members:    fRNAdb10:FR052921 FR160203      
NCBI13:Y08836    
NONCODE14:n385310 n341368 n341366 n387660 n341367      
RNAdb15:EVF35719 ASO2280    

Export aliases for FABP5P3 gene to outside databases


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for FABP5P3 Gene: 
FABP5P3 (fatty acid binding protein 5 pseudogene 3) is a pseudogene, and is affiliated with the lncRNA class. GO annotations related to this gene include lipid binding and transporter activity.

UniProtKB/Swiss-Prot: FB5L3_HUMAN, A8MUU1
Function: High specificity for fatty acids (By similarity)



fRNAdb sequence ontologies for FABP5P3 - the ORGUL cluster for this gene includes several descriptions:
nc_conserved_region - Non-coding region of sequence similarity by descent from a common ancestor.
antisense_RNA - Antisense RNA is RNA that is transcribed from the coding, rather than the template, strand of DNA. It is therefore complementary to mRNA.

View fRNAdb secondary structures for FABP5P3

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NC_018918.2  NT_007914.15  NT_079596.2  
Regulatory elements:
   Search SABiosciences Regulatory transcription factor binding sites for FABP5P3
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for FABP5P3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FABP5P3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q36.1   Ensembl cytogenetic band:  7q36.1   HGNC cytogenetic band: 7q36.1

FABP5P3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FABP5P3 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P152137:  view genomic region     (about GC identifiers)

Start:
152,133,980 bp from pter      End:
152,140,272 bp from pter
Size:
6,293 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 151,461,151-151,467,272     
ORGUL member locations:
Legend (see complete legend)

ORGUL Member Locations for FABP5P3

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: FB5L3_HUMAN, A8MUU1 (See protein sequence)
Recommended Name: Putative fatty acid-binding protein 5-like protein 3  
Size: 101 amino acids; 11299 Da
Caution: Could be the product of a pseudogene

Explore the universe of human proteins at neXtProt for FABP5P3: NX_A8MUU1

Explore proteomics data for FABP5P3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_A8MUU1

  • FABP5P3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    FABP5P3 Protein Expression

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    4 InterPro protein domains:
     IPR012674 Calycin
     IPR011038 Calycin-like
     IPR000463 Fatty_acid-bd
     IPR000566 Lipocln_cytosolic_FA-bd_dom

    Graphical View of Domain Structure for InterPro Entry A8MUU1

    ProtoNet protein and cluster: A8MUU1

    UniProtKB/Swiss-Prot: FB5L3_HUMAN, A8MUU1
    Domain: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior (By similarity)
    Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family


    FABP5P3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FB5L3_HUMAN, A8MUU1
    Function: High specificity for fatty acids (By similarity)

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0008289lipid binding IEA--
         
    FABP5P3 for ontologies           About GeneDecksing


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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for FABP5P3

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
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    Browse Tocris compounds for FABP5P3 (FB5L3)

    Search CenterWatch for drugs/clinical trials and news about FABP5P3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
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    About This Section
    2 fRNAdb Secondary structures:


    Unigene Cluster for FABP5P3:

    Fatty acid binding protein 5 pseudogene 3
    Hs.647108  [show with all ESTs]
    Unigene Representative Sequence: BX338084
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000477993(uc003wlb.3) ENST00000437960
    miRNA
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    Additional mRNA sequence: NR_002935.1 

    1 DOTS entry:

    DT.100770877 

    4 AceView cDNA sequences:

    CR621082 BX338084 BG214513 BX338083 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FABP5P3 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    FABP5P3 Expression
    About this image


    See FABP5P3 Protein Expression from SPIRE MOPED and PaxDB
    SOURCE GeneReport for Unigene cluster: Hs.647108
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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP5P3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
      --

    ENSEMBL Gene Tree for FABP5P3 (if available)
    TreeFam Gene Tree for FABP5P3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FABP5P3 gene
    9 SIMAP similar genes for FABP5P3 using alignment to 1 protein entry:     FB5L3_HUMAN:
    FABP5    FABP9    FABP4    PMP2    DKFZp547J2313    FABP3
    FABP7    FABP12    CRABP2

    FABP5P3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/91 SNPs in FABP5P3 are shown (see all 91)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1393300511,2
    --145944402(+) AAGCCA/CCTTAC 1 -- us2k10--------
    rs1831758781,2
    --152135386(+) AGATGA/GTGATG 1 -- int10--------
    rs1400479941,2
    --152135436(+) CCACTA/GTGAGC 1 -- int10--------
    rs1155625991,2
    C,F--152135473(+) GCTGAT/CAGCAG 1 -- int11Minor allele frequency- C:0.05WA 118
    rs1885543961,2
    --152135675(+) AAATTA/GTGAAA 1 -- int10--------
    rs731645591,2
    C--152135676(+) AATTAC/TGAAAG 1 -- int11Minor allele frequency- T:0.50CSA 2
    rs284510661,2
    C,F--152135702(+) ATCTGG/AAAACA 1 -- int17Minor allele frequency- A:0.11NA CSA WA EA 365
    rs284803441,2
    C,F--152135706(+) GGAAAC/TAGTAC 1 -- int17Minor allele frequency- T:0.08NA CSA WA EA 365
    rs286640921,2
    C,F--152135721(+) TACAAC/TAGAAA 1 -- int14Minor allele frequency- T:0.04NA 126
    rs610480511,2
    C--152135899(+) TAATC-/ATATATA 1 -- int10--------

    HapMap Linkage Disequilibrium report for FABP5P3 (152133980 - 152140272 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FABP5P3: --
    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FABP5P3 for disorders           About MalaCards
    OMIM information: 606833    

    FABP5P3 for disorders           About GeneDecksing


    Export disorders for FABP5P3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FABP5P3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with FABP5P3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    2. Hepatitis C virus core protein interacts with 14-3-3 protein and activates the kinase Raf-1. (PubMed id )2 Aoki H.... Hino O. (2000)
    3. (PubMed id 16628248)10 
    4. (PubMed id 15608161)10 

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 220832 HGNC: 22573 AceView: FABP5L3 Ensembl:ENSG00000241735 euGenes: HUgn220832
    ECgene: FABP5P3 H-InvDB: FABP5P3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FABP5P3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FABP5P3 gene:
    Search GeneIP for patents involving FABP5P3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
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    About This Section

     
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     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Biologicals
     Novus Tissue Slides
     Search for Antibodies for FABP5P3 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for FABP5P3
     Custom Antibody / Protein Production Service
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     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     Browse Proteins at Cloud-Clone Corp.
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     Search LifeMap BioReagents cell lines for FABP5P3
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     Browse SwitchGear 3'UTR luciferase reporter plasmids for FABP5P3
     Browse SwitchGear Promoter luciferase reporter plasmids for FABP5P3
     Search ThermoFisher Antibodies for FABP5P3
     Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat FABP5P3
     inGenious Targeting Laboratory - Custom generated mouse model solutions for FABP5P3
     inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for FABP5P3
    Customized:
     lentivirus for stable overexpression of FABP5P3
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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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    (GIFtS: 73)
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