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FABP5 Gene

protein-coding   GIFtS: 59
GCID: GC08P082242

Fatty Acid Binding Protein 5 (Psoriasis-Associated)

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Fatty Acid Binding Protein 5 (Psoriasis-Associated)1 2     EFABP2 5
Epidermal-Type Fatty Acid-Binding Protein2 3     PAFABP2 5
Psoriasis-Associated Fatty Acid-Binding Protein Homolog2 3     KFABP2
E-FABP2 3     Fatty Acid-Binding Protein, Epidermal2
PA-FABP2 3     Fatty Acid-Binding Protein 53

External Ids:    HGNC: 35601   Entrez Gene: 21712   Ensembl: ENSG000001646877   OMIM: 6051685   UniProtKB: Q014693   

Export aliases for FABP5 gene to outside databases

Previous GC identifers: GC08P081070 GC08P082241 GC08P081915 GC08P082355 GC08P077682


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for FABP5 Gene:
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being
upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic
proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid
uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human
genome contains many pseudogenes similar to this locus.(provided by RefSeq, Feb 2011)

GeneCards Summary for FABP5 Gene:
FABP5 (fatty acid binding protein 5 (psoriasis-associated)) is a protein-coding gene. Diseases associated with FABP5 include bladder squamous cell carcinoma, and psoriasis. GO annotations related to this gene include transporter activity and fatty acid binding. An important paralog of this gene is RBP5.

UniProtKB/Swiss-Prot: FABP5_HUMAN, Q01469
Function: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or
introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation

Gene Wiki entry for FABP5 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000008.11  NC_018919.2  NT_008183.20  
Regulatory elements:
   Regulatory transcription factor binding sites in the FABP5 gene promoter:
         SRF   c-Fos   AP-1   SRF (504 AA)   STAT5A   C/EBPalpha   HNF-1A   CHOP-10   HNF-1   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidFABP5 promoter sequence
   Search Chromatin IP Primers for FABP5

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat FABP5


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 8q21.13   Ensembl cytogenetic band:  8q21.13   HGNC cytogenetic band: 8q21.13

FABP5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FABP5 gene location

GeneLoc information about chromosome 8         GeneLoc Exon Structure

GeneLoc location for GC08P082242:  view genomic region     (about GC identifiers)

Start:
82,192,598 bp from pter      End:
82,197,012 bp from pter
Size:
4,415 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: FABP5_HUMAN, Q01469 (See protein sequence)
Recommended Name: Fatty acid-binding protein, epidermal  
Size: 135 amino acids; 15164 Da
4 PDB 3D structures from and Proteopedia for FABP5:
1B56 (3D)        1JJJ (3D)        4AZM (3D)        4AZR (3D)    
Secondary accessions: B2R4K0

Explore the universe of human proteins at neXtProt for FABP5: NX_Q01469

Explore proteomics data for FABP5 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys17, Lys24, Lys34, Lys61, Lys82
  • Modification sites at PhosphoSitePlus

  • See FABP5 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_001435.1  
    ENSEMBL proteins: 
     ENSP00000297258   ENSP00000379647  

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    FABP: Fatty acid binding protein family

    4 InterPro protein domains:
     IPR012674 Calycin
     IPR011038 Calycin-like
     IPR000463 Fatty_acid-bd
     IPR000566 Lipocln_cytosolic_FA-bd_dom

    Graphical View of Domain Structure for InterPro Entry Q01469

    ProtoNet protein and cluster: Q01469

    1 Blocks protein domain: IPB000463 Cytosolic fatty-acid binding protein

    UniProtKB/Swiss-Prot: FABP5_HUMAN, Q01469
    Domain: Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior
    Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family


    FABP5 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FABP5_HUMAN, Q01469
    Function: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or
    introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005215transporter activity IEA--
    GO:0005504fatty acid binding IEA--
    GO:0005515protein binding IPI12839573
    GO:0008289lipid binding TAS1512466
         
    FABP5 for ontologies           About GeneDecksing


    Phenotypes:
         9 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Fabp5):
     adipose tissue  cardiovascular system  growth/size/body  homeostasis/metabolism  immune system 
     integument  liver/biliary system  mortality/aging  muscle 

    FABP5 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Fabp5tm1Hota for FABP5

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for FABP5
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       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for FABP5

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    Browse Sino Biological Human cDNA Clones
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP5


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    FABP5_HUMAN, Q01469: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol3
    extracellular3
    plasma membrane3
    nucleus2
    mitochondrion1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm TAS16130169
    GO:0070062extracellular vesicular exosome IDA--

    FABP5 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for FABP5 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1PPAR signaling pathway
    PPAR signaling pathway

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways




    1 Kegg Pathway  (Kegg details for FABP5):
        PPAR signaling pathway


    FABP5 for pathways           About GeneDecksing

        Pathway & Disease-focused RT2 Profiler PCR Arrays including FABP5: 
              Fatty Acid Metabolism in human mouse rat
              Fatty Liver in human mouse rat
              PPAR Targets in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for FABP5

    STRING Interaction Network Preview (showing 5 interactants - click image to see 9)

    Selected Interacting proteins for FABP5 (Q014693 ENSP000002972584) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    S100A7P311513, ENSP000003577114I2D: score=3 STRING: ENSP00000357711
    AURKAO149653, ENSP000002169114I2D: score=1 STRING: ENSP00000216911
    CDK2P249413, ENSP000002669704I2D: score=1 STRING: ENSP00000266970
    SLX4Q8IY923, ENSP000002940084I2D: score=1 STRING: ENSP00000294008
    PPP2R2AP631513, ENSP000003701134I2D: score=1 STRING: ENSP00000370113
    About this table

    Gene Ontology (GO): Selected biological process terms (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006006glucose metabolic process IEA--
    GO:0006629lipid metabolic process TAS8092987
    GO:0006656phosphatidylcholine biosynthetic process IEA--
    GO:0008544epidermis development TAS1512466
    GO:0009611response to wounding IEA--

    FABP5 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for FABP5

    1 DrugBank Compound for FABP5    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Palmitic Acid1-Hexyldecanoic Acid (see all 11)57-10-3carrier--17139284 17016423

    Selected Novoseek inferred chemical compound relationships for FABP5 gene (see all 11)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fatty acid 73.6 82 12839573 (6), 10191275 (3), 8092987 (3), 17066326 (2) (see all 37)
    retinoic acid 51.6 5 19861119 (2), 7881766 (1), 8427590 (1), 8092987 (1)
    sodium dodecylsulfate 42.3 5 7881766 (1), 9255481 (1)
    stearic acid 34.5 1 8092987 (1)
    palmitate 33.1 1 9719561 (1)
    oleic acid 29.7 1 8427590 (1)
    lipid 9.29 8 19434059 (2), 8726632 (1), 17066326 (1)
    cholesterol 0 3 19434059 (2), 8092987 (1)
    arachidonic acid 0 3 15342681 (3)
    steroid 0 3 9059669 (2)



    FABP5 for compounds           About GeneDecksing



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for FABP5 gene: 
    NM_001444.2  

    Unigene Cluster for FABP5:

    Fatty acid binding protein 5 (psoriasis-associated)
    Hs.408061  [show with all ESTs]
    Unigene Representative Sequence: BM563703
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000297258(uc003yca.2) ENST00000396359 ENST00000486269 ENST00000481695


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      QuantiTect SYBR Green Assays in human, mouse, rat FABP5
      QuantiFast Probe-based Assays in human, mouse, rat FABP5

    Additional mRNA sequence: 

    AK226036.1 AK311856.1 BC019385.2 BC070303.1 BT007449.1 M94856.1 

    15 DOTS entries:

    DT.97802928  DT.454265  DT.99987236  DT.40106155  DT.92441159  DT.91996889  DT.120636050  DT.95139161 
    DT.40106154  DT.95139191  DT.92347605  DT.95085635  DT.95139189  DT.92441155  DT.97857218 

    Selected AceView cDNA sequences (see all 199):

    AA595972 AI190490 BU735012 BX477417 CB155123 BM314216 BM789868 AI720035 
    BM314523 BQ446473 CD677981 AI685547 BM712171 BF726770 BM689083 AW805859 
    BM851685 BG057135 AW063865 F31730 BG678687 AW080296 AA101190 BM797928 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    FABP5 expression in normal human tissues (normalized intensities)      FABP5 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: CAGCTATTTC
    FABP5 Expression
    About this image


    FABP5 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 5) fully expand
     
     Ovary (Reproductive System)
             Ovarian Somatic Cells Ovigerous Cord
     
     Testis (Reproductive System)
             Pre-Sertoli Cells Testis Cord
     
     Liver (Hepatobiliary System)
             Perivenous Hepatocytes Liver Lobule
     
     Adipose (Muscoskeletal System)
     
     Esophagus (Gastrointestinal Tract)
    FABP5 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    FABP5 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.408061

    UniProtKB/Swiss-Prot: FABP5_HUMAN, Q01469
    Tissue specificity: Keratinocytes; highly expressed in psoriatic skin

        Pathway & Disease-focused RT2 Profiler PCR Arrays including FABP5: 
              Fatty Acid Metabolism in human mouse rat
              Fatty Liver in human mouse rat
              PPAR Targets in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for FABP5

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for FABP5 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Fabp51 , 5 fatty acid binding protein 5, epidermal1, 5 80.49(n)1
    80(a)1
      3 (2.47 cM)5
    165921  NM_010634.31  NP_034764.11 
     100125485 
    chicken
    (Gallus gallus)
    Aves FABP51 fatty acid binding protein 5 (psoriasis-associated) 70.13(n)
    64.8(a)
      420197  NM_001006346.1  NP_001006346.1 
    lizard
    (Anolis carolinensis)
    Reptilia FABP56
    fatty acid binding protein 5 (psoriasis-associated...
    62(a)
    1 ↔ 1
    4(24557632-24571922)


    ENSEMBL Gene Tree for FABP5 (if available)
    TreeFam Gene Tree for FABP5 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for FABP5 gene
    RBP52  FABP92  CRABP22  FABP122  FABP42  FABP32  RBP12  RBP22  
    CRABP12  FABP22  PMP22  FABP72  RBP72  
    15 SIMAP similar genes for FABP5 using alignment to 3 protein entries:     FABP5_HUMAN (see all proteins):
    FABP5P3    FABP4    FABP9    PMP2    DKFZp547J2313    FABP3
    FABP7    FABP12    CRABP2    RBP1    RBP5    CRABP1
    FABP2    RBP2    RBP7

    FABP5 for paralogs           About GeneDecksing


    Selected Pseudogenes.org Pseudogenes for FABP5 (see all 12)
    PGOHUM00000248462 PGOHUM00000247229 PGOHUM00000247257 PGOHUM00000246198 PGOHUM00000240521


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for FABP5 (see all 164)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 8 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs560898681,2
    C--82289183(+) GGAAAG/TAATCT 1 -- us2k10--------
    rs1160333561,2
    F--82289250(+) ATGCAT/ACAGAT 1 -- us2k11Minor allele frequency- A:0.03WA 118
    rs1880409551,2
    --82289345(+) TAACGG/TTTATT 1 -- us2k10--------
    rs785032311,2
    C,F--82289378(+) TTGTCT/CGTATG 1 -- us2k11Minor allele frequency- C:0.08WA 118
    rs745572381,2
    C,F--82289498(+) TAGTAC/TTCCAG 1 -- us2k11Minor allele frequency- T:0.06NA 120
    rs736945271,2
    C,F--82289553(+) CATTTA/TAAAAT 1 -- us2k12Minor allele frequency- T:0.09WA 120
    rs1122199491,2
    C--82289670(+) GCCCT-/AAGGAG 1 -- us2k11Minor allele frequency- A:0.50CSA 2
    rs755192811,2
    F--82289798(+) CCTTAT/CTGGGA 1 -- us2k11Minor allele frequency- C:0.03WA 118
    rs1430982051,2
    --82289840(+) AAGACC/TGGTGT 1 -- us2k10--------
    rs1508636131,2
    --82289848(+) TGTGAA/CCCTAA 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for FABP5 (82192598 - 82197012 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for FABP5: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing FABP5
    DNA2.0 Custom Variant and Variant Library Synthesis for FABP5

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605168    OMIM disorders: --

    Selected diseases for FABP5 (see all 40):    About MalaCards
    bladder squamous cell carcinoma    psoriasis    bladder transitional cell carcinoma    transitional cell carcinoma
    vaginitis    oral squamous cell carcinoma    skin disease    mycosis fungoides
    contact dermatitis    dermatitis    squamous cell carcinoma    esophageal squamous cell carcinoma
    atopic dermatitis    bipolar disorder    down syndrome    endometrial carcinoma
    obesity    prostate cancer    hypoxia    intrahepatic cholangiocarcinoma


    FABP5 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Selected Novoseek inferred disease relationships for FABP5 gene (see all 11)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    psoriasis 51.3 7 8726632 (2), 12839573 (1), 8427590 (1), 12804984 (1) (see all 6)
    carcinoma squamous cell 35.2 12 8726632 (3), 20040021 (2), 19339807 (1), 8824783 (1) (see all 7)
    breast cancer 6.03 12 18359695 (2), 16471039 (1)
    skin diseases 5.2 2 8726632 (1), 10331666 (1)
    shock 3.69 2 16115757 (1), 19294697 (1)
    inflammation 0 1 19339807 (1)
    metastasis 0 3 18360704 (1), 12459653 (1)
    tumors 0 6 9307301 (2), 18359695 (2), 19337991 (2)
    carcinoma 0 2 15922867 (1), 17428383 (1)
    obesity 0 5 17359244 (2), 17472010 (1)

    Genetic Association Database (GAD): FABP5
    Human Genome Epidemiology (HuGE) Navigator: FABP5 (4 documents)

    Export disorders for FABP5 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for FABP5 gene, integrated from 10 sources (see all 121):
    (articles sorted by number of sources associating them with FABP5)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and expression of a novel keratinocyte protein (psoriasis-associated fatty acid-binding protein [PA-FABP]) that is highly up-regulated in psoriatic skin and that shares similarity to fatty acid-binding proteins. (PubMed id 1512466)1, 2, 3, 9 Madsen P.S.... Celis J.E. (J. Invest. Dermatol. 1992)
    2. Purification and characterization of the human epidermal fatty acid- binding protein: localization during epidermal cell differentiation in vivo and in vitro. (PubMed id 8092987)1, 2, 9 Siegenthaler G.... Saurat J.-H. (Biochem. J. 1994)
    3. Expression, purification and crystal structure determination of recombinant human epidermal-type fatty acid-binding protein. (PubMed id 10493790)1, 2, 9 Hohoff C.... van Tilbeurgh H. (Biochemistry 1999)
    4. Polymorphism screening of brain-expressed FABP7, 5 and 3 genes and association studies in autism and schizophrenia in Japanese subjects. (PubMed id 20057506)1, 4 Maekawa M....Yoshikawa T. (J. Hum. Genet. 2010)
    5. Association analyses between brain-expressed fatty-acid binding protein (FABP) genes and schizophrenia and bipolar disorder. (PubMed id 19554614)1, 4 Iwayama Y....Yoshikawa T. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    6. Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. (PubMed id 15592455)1, 2 Rush J.... Comb M.J. (Nat. Biotechnol. 2005)
    7. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    8. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (Nat. Biotechnol. 2003)
    9. Solution structure and backbone dynamics of human epidermal-type fatty acid-binding protein (E-FABP). (PubMed id 12049637)1, 2 Gutierrez-Gonzalez L.H.... Luecke C. (Biochem. J. 2002)
    10. Microsequences of 145 proteins recorded in the two-dimensional gel protein database of normal human epidermal keratinocytes. (PubMed id 1286667)1, 2 Rasmussen H.H....Vandekerckhove J. (Electrophoresis 1992)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 2171 HGNC: 3560 AceView: FABP5 Ensembl:ENSG00000164687 euGenes: HUgn2171
    ECgene: FABP5 Kegg: 2171 H-InvDB: FABP5

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for FABP5 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for FABP5 gene:
    Search GeneIP for patents involving FABP5

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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