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FABP4 Gene

protein-coding GIFtS: 66

GC08M082553

fatty acid binding protein 4, adipocyte
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
A-FABP ^¹, ², ³
AFABP ^³
ALBP ^³
aP2 ^¹, ²

Descriptions
Adipocyte lipid-binding protein ^³
Fatty acid-binding protein 4 ^³
fatty acid binding protein 4, adipocyte ^²

External Ids
HGNC: 3559¹
Entrez Gene: 2167²
UniProtKB: P15090³
Ensembl: ENSG00000170323⁷

Search outside databases for aliases for FABP4 gene

Previous GC identifers: GC08M081268 GC08M082439 GC08M082113 GC08M082440

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

EntrezGene summary for FABP4:

FABP4 encodes the fatty acid binding protein found in adipocytes. Fatty acid binding proteins are a

family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other

hydrophobic ligands. It is thought that FABPs roles include fatty acid uptake, transport, and

metabolism. [provided by RefSeq]

UniProtKB/Swiss-Prot: FABP4_HUMAN, P15090

Function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic

acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus

(By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the FABP4 gene

Entrez Gene cytogenetic band: 8q21 Ensembl cytogenetic band: 8q21.13 HGNC cytogenetic band: 8q21

FABP4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 8 GeneLoc Exon Structure

GeneLoc location for GC08M082553: (about GC identifiers)

Start:	82,553,481 bp from pter
End:	82,558,023 bp from pter
Size:	4,543 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000008.9 NT_008183.18

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: FABP4_HUMAN, P15090 (See protein sequence)

Recommended Name: Fatty acid-binding protein, adipocyte

Size: 132 amino acids; 14719 Da

Subunit: Homodimer. Interacts with PPARG (By similarity). Monomer

Subcellular location: Cytoplasm. Nucleus. Note=Depending on the nature of the ligand, a

conformation change exposes a nuclear localization motif and the protein is transported into the

nucleus. Subject to constitutive nuclear export (By similarity)

PDB structures from and Proteopedia :

1TOU (3D)

1TOW (3D)

2HNX (3D)

2NNQ (3D)

3FR2 (3D)

3FR4 (3D)

3FR5 (3D)

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_001433.1

ENSEMBL proteins:

ENSP00000256104

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (FABP4)
	Human Recombinant Proteins from Abnova (FABP4)

OriGene Purified Recombinant Human Protein: FABP4

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005625	soluble fraction	TAS	2481498
GO:0005634	nucleus	IEA	--
GO:0005737	cytoplasm	TAS	16130169
GO:0005829	cytosol	IEA	--

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Antibodies for FABP4:

	Browse Antibodies Central at Invitrogen
	Millipore Mono- and Polyclonal Antibodies for the study of FABP4
	Sigma-Aldrich Antibodies for FABP4
	R&D Systems Antibodies for FABP4
	Cell Signaling Technology (CST) Antibodies for FABP4
	Antibodies from Abcam (FABP4), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (FABP4)
	Novus Biologicals Antibodies for FABP4

Assays for FABP4:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry P15090

ProtoNet protein and cluster: P15090

1 Blocks protein family: IPB000463 Cytosolic fatty-acid binding protein

UniProtKB/Swiss-Prot: FABP4_HUMAN, P15090

Domain: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior

Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FABP4)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FABP4)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001442

Applied Biosystems Silencer® siRNAs for FABP4

Sigma-Aldrich siRNA and siRNA Panels for FABP4

Sigma-Aldrich shRNA for FABP4

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for FABP4
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_001442
Myc/DDK tagged cDNA clone in CMV expression vector: NM_001442
untagged cDNA clone in CMV expression vector: NM_001442

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_001442

UniProtKB/Swiss-Prot: FABP4_HUMAN, P15090

Function: Lipid transport protein in adipocytes. Binds both long chain fatty acids and retinoic

acid. Delivers long-chain fatty acids and retinoic acid to their cognate receptors in the nucleus

fatty acid-binding protein 4,adipocyte

7 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Fabp4):

	adipose tissue	growth/size	homeostasis/metabolism	life span-post-weaning/aging
liver/biliary system	muscle

4 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005215	transporter activity	IEA	--
GO:0005504	fatty acid binding	TAS	2481498
GO:0005515	protein binding	IPI	17353931
GO:0016564	transcription repressor activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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1 Sigma-Aldrich "Your Favorite Gene" Pathway for FABP4 (Your Favorite Gene powered by Ingenuity)

LPS/IL-1 Mediated Inhibition of RXR Function

GeneDecks FABP4 for the pathways selected above

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Gene Network Central^TM Interacting Genes and Proteins Network for FABP4

5/33 Interacting proteins for FABP4 (P15090^{1, 2} ENSP00000256104³) via UniProtKB, MINT, and/or STRING (see all 33 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EXT2	Q93063¹	EBI-715333, EBI-1047761
OSTF1	Q92882¹	EBI-715333, EBI-1051152
SNCG	O76070¹	EBI-715333, EBI-1053810
LIPE	ENSP00000244289³	STRING (score=.998)
FABP1	ENSP00000295834³	STRING (score=.989)

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5/10 Gene Ontology (GO) biological process terms (links to tree view) (see all 10 ):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0001816	cytokine production	IEA	--
GO:0006469	negative regulation of protein kinase activity	IEA	--
GO:0006631	fatty acid metabolic process	IEA	--
GO:0006810	transport	IEA	--
GO:0008284	positive regulation of cell proliferation	IEA	--

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Sigma-Aldrich Small Molecules for FABP4:

Antagonist

Browse Tocris compounds for FABP4
10/20 Novoseek chemical compound relationships for FABP4 gene (see all 20 )

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
fatty acid	82.41	189	9516437 (5), 8357805 (3), 7547918 (2), 15456755 (2) (see all 98)
glycerol 3-phosphate	69.27	13	17242918 (1), 18448614 (1), 11983812 (1), 9709955 (1) (see all 8)
lipid	65.30	120	12794068 (5), 16313911 (4), 8463311 (3), 12417276 (3) (see all 52)
oleic acid	51.38	11	2223772 (3), 1648089 (2), 16870193 (1), 8634281 (1) (see all 7)
glucose	43.30	33	17620449 (3), 17635574 (3), 16919044 (2), 18063851 (1) (see all 17)
cholesterol ester	43.22	5	12417276 (2), 16313911 (1)
acyl-coa	40.57	8	12479581 (2), 12759900 (1), 14969395 (1), 15913765 (1) (see all 5)
sterol	32.99	4	14749206 (1), 18448614 (1), 19360322 (1), 18547799 (1)
carboxylate	32.03	3	9516437 (2), 8161548 (1)
cholesterol	24.70	34	16313911 (3), 17635574 (3), 18835952 (3), 19368945 (2) (see all 11)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (FABP4)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (FABP4)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_001442

Sigma-Aldrich siRNA and siRNA Panels for FABP4

Sigma-Aldrich shRNA for FABP4

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_001442

REFSEQ mRNAs for FABP4 gene:

NM_001442.2

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_001442

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_001442
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_001442
                                 untagged cDNA clone in CMV expression vector: NM_001442

Additional cDNA sequence:

BC003672.1 BT006809.1 CR456903.1 J02874.1

8 DOTS entries:

DT.217317 DT.100828346 DT.99971609 DT.100036595 DT.100740312 DT.100828347 DT.99995846 DT.91923234

24/270 AceView cDNA sequences (see all 270 ):

AI493086 BQ951142 AJ707063 BQ880795 AI094429 AI127007 H42609 BQ574690

F15904 AA046090 BQ575807 AA846215 CA407624 BQ720073 AA126737 BM929515

AA137055 BP381358 AI148406 BQ017120 F29476 BU742829 BM740297 AI400113

highest scoring ESTs for FABP4:

AA128249 AA046133 AA126737 AA137126 AA187496 AA319981 AA320009 AA320389 AA732844 AA777211

Unigene Cluster for FABP4:

Fatty acid binding protein 4, adipocyte

Hs.391561 [show with all ESTs]

Unigene Representative Sequence: CB999901

GeneLoc Exon Structure

3 Alternative Splicing Database (ASD) splice patterns (SP) for FABP4

ExUns:	1a	·	1b	^	2a	·	2b	^	3	^	4a	·	4b
SP1:
SP2:					-
SP3:

About this scheme

ECgene alternative splicing isoforms for FABP4

1 Ensembl transcript including schematic representation:

ENST00000256104

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

FABP4 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for FABP4

¹ / ² / ³

4 probe-sets matching FABP4 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
38430_at²^{, 3}	U95-A	1	1.00	1.00	0.99	1.25	AA128249	1.00	1.00	1.00	1
76163_at²^{, 3}	U95-E	1	0.38	1.00	0.96	0.75	AI766029	0.60	1.00	0.82	1
203980_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_001442	0.60	1.00	0.82	1
203980_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks FABP4 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: ATTTAGCAAG

SOURCE GeneReport for Unigene cluster: Hs.391561
Expression variation in blood from EXPOLDB for FABP4

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for FABP4 gene from 5/6 species (see all 6 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
chimpanzee (Pan troglodytes)	FABP4¹	--	fatty acid binding protein 4, adipocyte	99.75(n) 100(a)	464255 XM_519830.2 XP_519830.1
cow (Bos taurus)	FABP4¹	--	fatty acid binding protein 4, adipocyte	89.39(n) 84.09(a)	281759 NM_174314.2 NP_776739.1
rat (Rattus norvegicus)	Fabp4¹	--	fatty acid binding protein 4, adipocyte	83.84(n) 89.23(a)	79451 NM_053365.1 NP_445817.1
mouse (Mus musculus)	Fabp4^{1, 5}	3 (13.90 cM)⁵	fatty acid binding protein 4, adipocyte^{1, 5}	86.11(n)¹ 91.67(a)¹	11770¹ NM_024406.1¹ NP_077717.1¹ AA066537⁵ AK003143⁵ (see all 20)
chicken (Gallus gallus)	FABP4¹	--	fatty acid binding protein 4, adipocyte	73.48(n) 76.52(a)	374165 NM_204290.1 NP_989621.1

About this table Species with no ortholog for FABP4

ENSEMBL Gene Tree for FABP4

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for FABP4 gene

FABP9² FABP12² PMP2²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/49 NCBI SNPs in FABP4 are shown (see all 49 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 35)

AB	SNP ID	Valid	Chr 8 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs1054135^1,2	A,C,F,H,O	82553315(-)	`TAGGAG/AATAAC`	1	--	ut3¹		8	MN EU EA WA NA	744
	rs7826463^1,2	A,C,F,H	82559474(+)	`atttcG/Agacta`	1	--	ng3¹		4	EU EA WA	414
	rs1486006^1,2	C,F,H,O	82553172(+)	`AGCGGG/CTATAA`	1	--	ng5¹		12	MN EU EA WA NA	1164
	rs16909187^1,2	C,F,H	82553272(+)	`CTATGG/ATAAAG`	1	--	ng5¹		11	NA EU EA WA	980
--	rs16909225^1,2	F,H	82558914(+)	`ATGACA/GGAAGT`	1	--	ng3¹		7	NA EU EA WA	562
--	rs1486005^1,2	A,H	82553104(+)	`tagaaT/Cgtacc`	1	--	ng5¹		5	MN EU EA WA	600
--	rs14044^1,2	C,F	82553090(+)	`cccacT/Cggggg`	1	--	ng5¹		2	MN	372
--	rs16909192^1,2	F,H	82553398(+)	`AAGAAA/CTAATG`	1	--	ut3¹		7	NA EU EA WA	560
--	rs16909216^1,2	F	82558736(+)	`ATTGAG/AAAACT`	1	--	ng3¹		3	NA	142
	rs16909196^1,2	F	82553462(+)	`ATGAAT/AACATC`	1	--	ut3¹		3	NA	142

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HapMap Linkage Disequilibrium images for FABP4 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 600434

10/15 Novoseek disease relationships for FABP4 gene (see all 15 )

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
obesity	56.46	29	19368945 (4), 17656598 (4), 16423904 (2), 17359244 (1) (see all 13)
insulin resistance	56.27	21	19368945 (5), 17389279 (3), 16423904 (2), 18198986 (1) (see all 11)
insulin sensitivity	54.56	5	15015141 (2), 18063851 (1), 18436985 (1), 15686734 (1)
carcinoma transitional cell bladder	52.56	3	8840999 (1), 15734831 (1)
atherosclerosis	44.59	17	17510463 (3), 17396233 (1), 15686734 (1), 16423904 (1) (see all 10)
carcinoma transitional cell	27.38	2	19115207 (1)
bladder cancer	21.88	12	19115207 (2), 15734831 (1), 10935488 (1)
cardiovascular diseases	18.23	7	16423904 (1), 18419784 (1), 17389279 (1), 18849305 (1) (see all 5)
atherosclerotic plaque	10.58	1	12417276 (1)
inflammation	10.15	6	17656598 (2), 19217286 (1)

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Human Gene Mutation Database: FABP4
Genetic Association Database: FABP4
Human Genome Epidemiology Navigator: FABP4 (6 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/206 PubMed articles for FABP4 gene (see all 206 ):

Human adipocyte lipid-binding protein: purification of the protein and cloning of its complementary DNA. (PubMed id 2481498)^{2, 3, 4} Baxa C.A.... Bernlohr D.A. (1989)
Genetic variation in fatty acid-binding protein-4 and peroxisome proliferator-activated receptor gamma interactively influence insulin sensitivity and body composition in males. (PubMed id 15015141)^{1, 3, 6} Damcott C.M....Ferrell R.E. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
A-FABP--a biomarker associated with the metabolic syndrome and/or an indicator of weight change? (PubMed id 18535557)^{1, 3} Engl J....Ebenbichler C.F. (2008)
Presence of fatty-acid-binding protein 4 expression in human epicardial adipose tissue in metabolic syndrome. (PubMed id 18417367)^{1, 3} Vural B....Buyukdevrim A.S. (2008)
In vitro phosphorylation of the adipocyte lipid-binding protein (p15) by the insulin receptor. Effects of fatty acid on receptor kinase and substrate phosphorylation. (PubMed id 1648089)^{1, 3} Buelt M.K....Bernlohr D.A. (1991)
Loss of expression of the adipocyte-type fatty acid-binding protein (A-FABP) is associated with progression of human urothelial carcinomas. (PubMed id 15734831)^{1, 3} Ohlsson G....Celis J.E. (2005)
The adipocyte lipid binding protein (ALBP/aP2) gene facilitates foam cell formation in human THP-1 macrophages. (PubMed id 12417276)^{1, 3} Fu Y....Garvey W.T. (2002)
Lipid metabolism mediated by adipocyte lipid binding protein (ALBP/aP2) gene expression in human THP-1 macrophages. (PubMed id 16313911)^{1, 3} Fu Y....Garvey W.T. (2006)
A-FABP, a candidate progression marker of human transitional cell carcinoma of the bladder, is differentially regulated by PPAR in urothelial cancer cells. (PubMed id 19115207)^{1, 3} Boiteux G....Fauconnet S. (2009)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 2167	HGNC: 3559	AceView: FABP4	Ensembl:ENSG00000170323	euGenes: HUgn2167
ECgene: FABP4	H-InvDB: FABP4

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for FABP4
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for FABP4:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for FABP4-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for FABP4		Antibodies for FABP4
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for FABP4		Small molecules for FABP4
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (FABP4)
	Antibodies (FABP4)
	Chimera RNAi (FABP4)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Antibodies & Assays for FABP4

	Recombinant Proteins (FABP4)
	Antibodies (FABP4)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for FABP4

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for FABP4

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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FABP4 Gene

protein-coding GIFtS: 66

Aliases &
Descriptions
for FABP4

Summaries
for FABP4

Genomic Location
for FABP4

Proteins
for FABP4

Protein Domains/
Families
for FABP4

Gene Function
for FABP4

Pathways & Interactions
for FABP4

Drugs & Compounds
for FABP4

Transcripts
for FABP4

Expression
for FABP4

Orthologs
for FABP4

Paralogs
for FABP4

SNPs/Variants
for FABP4

Disorders & Mutations
for FABP4

Medical News
for FABP4

Publications
for FABP4

Search for FABP4

Genome Databases showing FABP4

Other Databases showing FABP4

Specialized Databases showing FABP4

Licensable Technologies
for FABP4

Services
for FABP4

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

FABP4 Gene

protein-coding GIFtS: 66

Aliases & Descriptionsfor FABP4

Summariesfor FABP4

Genomic Locationfor FABP4

Proteinsfor FABP4

Protein Domains/Familiesfor FABP4

Gene Functionfor FABP4

Pathways & Interactionsfor FABP4

Drugs & Compoundsfor FABP4

Transcriptsfor FABP4

Expression for FABP4

Orthologsfor FABP4

Paralogsfor FABP4

SNPs/Variantsfor FABP4

Disorders & Mutationsfor FABP4

Medical Newsfor FABP4

Publicationsfor FABP4

Search for FABP4

Genome Databases showing FABP4

Other Databases showing FABP4

Specialized Databases showing FABP4

Licensable Technologiesfor FABP4

Servicesfor FABP4

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for FABP4

Summaries
for FABP4

Genomic Location
for FABP4

Proteins
for FABP4

Protein Domains/
Families
for FABP4

Gene Function
for FABP4

Pathways & Interactions
for FABP4

Drugs & Compounds
for FABP4

Transcripts
for FABP4

Expression
for FABP4

Orthologs
for FABP4

Paralogs
for FABP4

SNPs/Variants
for FABP4

Disorders & Mutations
for FABP4

Medical News
for FABP4

Publications
for FABP4

Licensable Technologies
for FABP4

Services
for FABP4