Aliases for FABP2 Gene
External Ids for FABP2 Gene
Previous GeneCards Identifiers for FABP2 Gene
The protein encoded by this gene is an intracellular fatty acid-binding protein that participates in the uptake, intracellular metabolism, and transport of long-chain fatty acids. The encoded protein is also involved in the modulation of cell growth and proliferation. This protein binds saturated long-chain fatty acids with high affinity, and may act as a lipid sensor to maintain energy homeostasis. [provided by RefSeq, Aug 2017]
GeneCards Summary for FABP2 Gene
FABP2 (Fatty Acid Binding Protein 2) is a Protein Coding gene. Diseases associated with FABP2 include Perinatal Necrotizing Enterocolitis and Refractory Celiac Disease. Among its related pathways are Lipoprotein metabolism and Fat digestion and absorption. Gene Ontology (GO) annotations related to this gene include transporter activity and fatty acid binding.
UniProtKB/Swiss-Prot for FABP2 Gene
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.