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Aliases for FABP12 Gene

Aliases for FABP12 Gene

  • Fatty Acid Binding Protein 12 2 3 5

External Ids for FABP12 Gene

Previous GeneCards Identifiers for FABP12 Gene

  • GC08M082602
  • GC08M082437
  • GC08M077927

Summaries for FABP12 Gene

GeneCards Summary for FABP12 Gene

FABP12 (Fatty Acid Binding Protein 12) is a Protein Coding gene. Among its related pathways are Metabolism and Lipoprotein metabolism. GO annotations related to this gene include transporter activity and lipid binding. An important paralog of this gene is FABP3.

UniProtKB/Swiss-Prot for FABP12 Gene

  • May play a role in lipid transport.

No data available for Entrez Gene Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for FABP12 Gene

Genomics for FABP12 Gene

Regulatory Elements for FABP12 Gene

Enhancers for FABP12 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around FABP12 on UCSC Golden Path with GeneCards custom track

Genomic Location for FABP12 Gene

81,524,981 bp from pter
81,590,596 bp from pter
65,616 bases
Minus strand

Genomic View for FABP12 Gene

Genes around FABP12 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
FABP12 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for FABP12 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for FABP12 Gene

Proteins for FABP12 Gene

  • Protein details for FABP12 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Fatty acid-binding protein 12
    Protein Accession:
    Secondary Accessions:
    • B7SUN0

    Protein attributes for FABP12 Gene

    140 amino acids
    Molecular mass:
    15565 Da
    Quaternary structure:
    No Data Available

neXtProt entry for FABP12 Gene

Proteomics data for FABP12 Gene at MOPED

Post-translational modifications for FABP12 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for FABP12 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for FABP12 Gene

Domains & Families for FABP12 Gene

Gene Families for FABP12 Gene

Protein Domains for FABP12 Gene

Suggested Antigen Peptide Sequences for FABP12 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
  • Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
genes like me logo Genes that share domains with FABP12: view

Function for FABP12 Gene

Molecular function for FABP12 Gene

UniProtKB/Swiss-Prot Function:
May play a role in lipid transport.

Phenotypes for FABP12 Gene

GenomeRNAi human phenotypes for FABP12:
genes like me logo Genes that share phenotypes with FABP12: view

Animal Model Products

CRISPR Products

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for FABP12 Gene

Localization for FABP12 Gene

Subcellular locations from

Jensen Localization Image for FABP12 Gene COMPARTMENTS Subcellular localization image for FABP12 gene
Compartment Confidence
cytosol 5
nucleus 2
extracellular 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for FABP12 Gene

Pathways & Interactions for FABP12 Gene

genes like me logo Genes that share pathways with FABP12: view

Interacting Proteins for FABP12 Gene

Gene Ontology (GO) - Biological Process for FABP12 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0044281 small molecule metabolic process TAS --
genes like me logo Genes that share ontologies with FABP12: view

No data available for SIGNOR curated interactions for FABP12 Gene

Drugs & Compounds for FABP12 Gene

(17) Drugs for FABP12 Gene - From: Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials

(29) Additional Compounds for FABP12 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with FABP12: view

Transcripts for FABP12 Gene

mRNA/cDNA for FABP12 Gene

(6) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for FABP12 Gene

Fatty acid binding protein 12:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for FABP12 Gene

No ASD Table

Relevant External Links for FABP12 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for FABP12 Gene

mRNA expression in normal human tissues for FABP12 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for FABP12 Gene

This gene is overexpressed in Testis (x23.8), Esophagus - Mucosa (x10.1), Vagina (x7.9), and Cervix - Ectocervix (x4.9).

SOURCE GeneReport for Unigene cluster for FABP12 Gene Hs.586370

mRNA Expression by UniProt/SwissProt for FABP12 Gene

Tissue specificity: Expressed in a number of retinoblastoma cell lines.
genes like me logo Genes that share expression patterns with FABP12: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for FABP12 Gene

Orthologs for FABP12 Gene

This gene was present in the common ancestor of mammals.

Orthologs for FABP12 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia FABP12 35
  • 85.95 (n)
  • 80.71 (a)
FABP12 36
  • 81 (a)
(Canis familiaris)
Mammalia FABP12 35
  • 86.67 (n)
  • 82.86 (a)
FABP12 36
  • 83 (a)
(Mus musculus)
Mammalia Fabp12 35
  • 84.73 (n)
  • 80.15 (a)
Fabp12 16
Fabp12 36
  • 80 (a)
(Pan troglodytes)
Mammalia FABP12 35
  • 99.52 (n)
  • 98.57 (a)
FABP12 36
  • 99 (a)
(Rattus norvegicus)
Mammalia Fabp12 35
  • 82.19 (n)
  • 80.15 (a)
(Monodelphis domestica)
Mammalia FABP12 36
  • 43 (a)
Species with no ortholog for FABP12:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for FABP12 Gene

Gene Tree for FABP12 (if available)
Gene Tree for FABP12 (if available)

Paralogs for FABP12 Gene

Paralogs for FABP12 Gene

(15) SIMAP similar genes for FABP12 Gene using alignment to 2 proteins: Pseudogenes for FABP12 Gene

genes like me logo Genes that share paralogs with FABP12: view

Variants for FABP12 Gene

Sequence variations from dbSNP and Humsavar for FABP12 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs2081757 -- 81,585,053(-) gaaac(A/C)atcaa intron-variant
rs2098996 -- 81,584,640(-) gaaag(G/T)aaatc intron-variant
rs2114695 -- 81,586,896(-) gaaac(A/G)tagga intron-variant
rs2114696 -- 81,586,866(-) gccct(G/T)ccaaa intron-variant
rs7833015 -- 81,582,575(+) taaaa(C/T)agact intron-variant

Structural Variations from Database of Genomic Variants (DGV) for FABP12 Gene

Variant ID Type Subtype PubMed ID
nsv465721 CNV Gain 19166990
nsv6274 CNV Insertion 18451855

Variation tolerance for FABP12 Gene

Residual Variation Intolerance Score: 85.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.15; 23.23% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for FABP12 Gene

Disorders for FABP12 Gene

Relevant External Links for FABP12

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for FABP12 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for FABP12 Gene

Publications for FABP12 Gene

  1. A novel fatty acid-binding protein (FABP) gene resulting from tandem gene duplication in mammals: transcription in rat retina and testis. (PMID: 18786628) Liu R.Z. … Godbout R. (Genomics 2008) 2 3 4 67
  2. GWAS meta-analysis and replication identifies three new susceptibility loci for ovarian cancer. (PMID: 23535730) Pharoah P.D. … Sellers T.A. (Nat. Genet. 2013) 3
  3. Genome-wide association for abdominal subcutaneous and visceral adipose reveals a novel locus for visceral fat in women. (PMID: 22589738) Fox C.S. … Borecki I.B. (PLoS Genet. 2012) 3
  4. Association analyses between brain-expressed fatty-acid binding protein (FABP) genes and schizophrenia and bipolar disorder. (PMID: 19554614) Iwayama Y. … Yoshikawa T. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010) 23
  5. ADRP/ADFP and Mal1 expression are increased in macrophages treated with TLR agonists. (PMID: 19748622) Feingold K.R. … Grunfeld C. (Atherosclerosis 2010) 23

Products for FABP12 Gene

Sources for FABP12 Gene