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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

FABP1 Gene

protein-coding   GIFtS: 64
GCID: GC02M088422

fatty acid binding protein 1, liver

 Explore 37 diseases affiliated with
FABP1 via our new
 Human Malady Compendium 
Biological research products
for FABP1
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

This gene clusters with an RNA gene
Subcategory (RNA class): lncRNA

Quality score for the ORGUL clustered with this gene is 3

Aliases
Fatty Acid Binding Protein 1, Liver1 2
L-FABP1 2 3
Fatty Acid-Binding Protein 12 3
Liver-Type Fatty Acid-Binding Protein2 3
FABPL2 3
Fatty Acid-Binding Protein, Liver2

External Ids:    HGNC: 35551   Entrez Gene: 21682   Ensembl: ENSG000001635867   OMIM: 1346505   UniProtKB: P071483   
ORGUL members:         
NONCODE:n333462    

Export aliases for FABP1 gene to outside databases

Previous GC identifers: GC02M087977 GC02M088715 GC02M088307 GC02M088324 GC02M088261 GC02M087344


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for FABP1:
This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small,
highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein
and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles
include fatty acid uptake, transport, and metabolism. (provided by RefSeq, Mar 2011)

UniProtKB/Swiss-Prot: FABPL_HUMAN, P07148
Function: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the
cytoplasm. May be involved in intracellular lipid transport

Gene Wiki entry for FABP1


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_022184.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the FABP1 gene promoter:
         GR   GR-beta   NF-kappaB   HNF-4alpha1   PPAR-gamma1   STAT3   GR-alpha   PPAR-gamma2   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): FABP1 promoter sequence
   Search SABiosciences Chromatin IP Primers for FABP1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat FABP1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p11   Ensembl cytogenetic band:  2p11.2   HGNC cytogenetic band: 2p11

FABP1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
FABP1 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M088422:  view genomic region     (about GC identifiers)

Start:
88,422,510 bp from pter      End:
88,427,635 bp from pter
Size:
5,126 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: FABPL_HUMAN, P07148 (See protein sequence)
Recommended Name: Fatty acid-binding protein, liver  
Size: 127 amino acids; 14208 Da
Subcellular location: Cytoplasm
6/19 PDB 3D structures from and Proteopedia for FABP1 (see all 19):
2F73 (3D)        2L67 (3D)        2L68 (3D)        2LKK (3D)        2PY1 (3D)        3B2H (3D)    

Explore the universe of human proteins at neXtProt for FABP1: NX_P07148

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_P07148

  • FABP1 Protein expression data from MOPED and PaxDb:    About this image 
    FABP1 Protein Expression
    REFSEQ proteins: NP_001434.1  
    ENSEMBL proteins: 
     ENSP00000295834   ENSP00000377351  
    Reactome Protein details: P07148
    Human Recombinant Protein Products for FABP1: 
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    Uscn Proteins for FABP1

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus ----
    GO:0005654nucleoplasm TAS--
    GO:0005737cytoplasm ----
    GO:0005782peroxisomal matrix ISS--
    GO:0005829cytosol IEA--

    FABP1 for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    FABP1 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR012674 Calycin
     IPR011038 Calycin-like
     IPR000463 Fatty_acid-bd
     IPR000566 Lipocln_cytosolic_FA-bd_dom

    Graphical View of Domain Structure for InterPro Entry P07148

    ProtoNet protein and cluster: P07148

    1 Blocks protein family: IPB000463 Cytosolic fatty-acid binding protein

    UniProtKB/Swiss-Prot: FABPL_HUMAN, P07148
    Domain: Forms a beta-barrel structure that accommodates hydrophobic ligands in its interior
    Similarity: Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: FABPL_HUMAN, P07148
    Function: Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the
    cytoplasm. May be involved in intracellular lipid transport

         Genatlas biochemistry entry for FABP1:
    fatty acid binding protein 1,liver

         Gene Ontology (GO): 5/9 molecular function terms (GO ID links to tree view) (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003682chromatin binding IEA--
    GO:0005215transporter activity ----
    GO:0005324long-chain fatty acid transporter activity IEA--
    GO:0005504fatty acid binding IEA--
    GO:0005543phospholipid binding IEA--
         
    FABP1 for ontologies           About GeneDecksing


    Phenotypes:
         2 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Fabp1):
     homeostasis/metabolism  liver/biliary system 

    FABP1 for phenotypes           About GeneDecksing

    Animal Models:
         Mouse knock-out Fabp1tm1Bin for FABP1
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    In Situ Assay
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    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for FABP1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways - 5/7 super-pathways (see all 7About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
    Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)1.00
    Fatty acid, triacylglycerol, and ketone body metabolism0.52
    PPARA Activates Gene Expression0.74
    2Metabolism
    Metabolism1.00
    Metabolism of lipids and lipoproteins0.34
    3Glucose / Energy Metabolism
    Glucose / Energy Metabolism1.00
    4Expression of FABP1
    Expression of FABP11.00
    5Selenium Metabolism and Selenoproteins
    Selenium Metabolism and Selenoproteins1.00

    Pathway sources
    See GeneCards unified pathways
    Show all pathways


    1 Cell Signaling Technology (CST) Pathway for FABP1
        Glucose / Energy Metabolism

    1 BioSystems Pathway for FABP1 
        Selenium Metabolism and Selenoproteins

    5/6        Reactome Pathways for FABP1 (see all 6)
        Expression of FABP1
    Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
    Metabolism
    PPARA Activates Gene Expression
    Fatty acid, triacylglycerol, and ketone body metabolism


    2         Kegg Pathways  (Kegg details for FABP1):
        PPAR signaling pathway
    Fat digestion and absorption


    FABP1 for pathways           About GeneDecksing

    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for FABP1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/15 Interacting proteins for FABP1 (P071483 ENSP000002958344) via UniProtKB, MINT, STRING, and/or I2D (see all 15)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PPARAQ078693, ENSP000002627354I2D: score=2 STRING: ENSP00000262735
    PPARGP372313, ENSP000002878204I2D: score=2 STRING: ENSP00000287820
    GRB2P629933, ENSP000003390074I2D: score=2 STRING: ENSP00000339007
    NR3C1P041503I2D: score=1 
    SNTA1Q134243I2D: score=1 
    About this table

    Gene Ontology (GO): 5/12 biological process terms (GO ID links to tree view) (see all 12):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006810transport ----
    GO:0008284positive regulation of cell proliferation IEA--
    GO:0015909long-chain fatty acid transport ----
    GO:0032000positive regulation of fatty acid beta-oxidation IEA--
    GO:0043066negative regulation of apoptotic process IDA16175609

    FABP1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    FABP1 for compounds           About GeneDecksing

    EMD Millipore small molecules for FABP1:
    Small Molecule - inhibitor
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    Browse Tocris compounds for FABP1

    4 DrugBank Compounds for FABP1    About this table
    CompoundSynonyms CAS #TypeActionsPubMed Ids
    Butenoic Acid-- 107-93-7carrier--17139284 17016423 10592235
    Oleic Acid-- 112-80-1carrier--17139284 17016423 10592235
    S-Methylcysteine-- 1187-84-4carrier--17139284 17016423 10592235
    Cholic Acid-- 81-25-4carrier--10592235

    10/35 Novoseek chemical compound relationships for FABP1 gene (see all 35)    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fatty acid 83.6 287 10064902 (5), 15138477 (5), 1699834 (5), 8664328 (4) (see all 99)
    oleoyl-coa 82.3 1 12479568 (1)
    11-(dansylamino)undecanoic acid 77.9 2 8053904 (1)
    etomoxir 54.6 1 7557264 (1)
    8-oxo-dg 54.2 10 19481229 (2), 16772708 (1), 19666118 (1), 17954367 (1) (see all 8)
    sterol 52.7 27 8609911 (7), 8895052 (2), 8431458 (2), 7547928 (1) (see all 8)
    bezafibrate 52.5 10 18368030 (5), 10064902 (1), 15708366 (1)
    oleic acid 52.1 11 10331654 (2), 8262919 (2), 7588781 (1), 11329616 (1) (see all 8)
    lipid 52 43 17698986 (3), 8431458 (3), 8664328 (2), 15249972 (2) (see all 23)
    acyl-coa 51.6 9 9395205 (1), 17627968 (1), 10428978 (1), 12213584 (1) (see all 6)

    Search CenterWatch for drugs/clinical trials and news about FABP1 / FABPL 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for FABP1 gene: 
    NM_001443.2  

    Unigene Cluster for FABP1:

    Fatty acid binding protein 1, liver
    Hs.380135  [show with all ESTs]
    Unigene Representative Sequence: BX641099
    4 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000295834(uc002sst.2) ENST00000393750 ENST00000495375 ENST00000472846


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    Additional cDNA sequence: 

    BC022287.1 BC032801.1 BX641099.1 CR542090.1 M10050.1 M10617.1 

    14 DOTS entries:

    DT.87016483  DT.91936262  DT.416902  DT.100743022  DT.416905  DT.100810634  DT.102827676  DT.87001698 
    DT.91744663  DT.121034754  DT.416906  DT.95094646  DT.95273281  DT.99939343 

    24/119 AceView cDNA sequences (see all 119):

    R29613 AA099433 M10617 AL531613 BM855492 BC032801 T68121 CB154162 
    AI742193 T53220 BM766943 AV647214 AV655309 AV661404 AV647083 BM768288 
    CR590669 CR612744 NM_001443 CR542090 AV681776 AI768596 BX406345 R29248 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for FABP1    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3a · 3b ^ 4a · 4b · 4c ^ 5
    SP1:                    -           -           -     -         
    SP2:                                -                           
    SP3:                    -           -                           
    SP4:                    -                                       


    ECgene alternative splicing isoforms for FABP1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    FABP1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: ACATTGGGTG
    FABP1 Expression
    About this image
    See FABP1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for FABP1

    SOURCE GeneReport for Unigene cluster: Hs.380135
        SABiosciences Expression via Pathway-Focused PCR Arrays including FABP1 (see all 6): 

              Fatty Acid Metabolism in human mouse rat
              Signal Transduction PathwayFinder in human mouse rat
              Hepatotoxicity in human mouse rat
              Fatty Liver in human mouse rat
              PPAR Targets in human mouse rat

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    In Situ
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    Search Advanced Cell Diagnostics for RNAscope RNA in situ hybridization assays for FABP1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of eukaryotes.

    Orthologs for FABP1 gene from 5/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves FABP11 fatty acid binding protein 1, liver 73.49(n)
    70.08(a)
      374015  NM_204192.2  NP_989523.1 
    lizard
    (Anolis carolinensis)
    Reptilia FABP16
    --
    65(a)
    1 ↔ 1
    6(59363519-59368027)
    African clawed frog
    (Xenopus laevis)
    Amphibia AF068301.12   -- 70.59(n)    AF068301.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.195772 Transcribed sequence with weak similarity to protein more 73.71(n)    BI846703.1 
    wheat
    (Triticum aestivum)
    Liliopsida CA607013.12   -- 73.13(n)    CA607013.1 


    ENSEMBL Gene Tree for FABP1 (if available)
    TreeFam Gene Tree for FABP1 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for FABP1 gene
    FABP62  
    2 SIMAP similar genes for FABP1 using alignment to 4 protein entries:     FABPL_HUMAN (see all proteins):
    FABP6    CRABP2

    FABP1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/145 NCBI SNPs in FABP1 are shown (see all 145    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1882341291,2
    --88422068(+) CTAAGA/CCCTTT 1 -- ds50010--------
    rs1512436231,2
    --88422085(+) CCTCCC/TACAGG 1 -- ds50010--------
    rs754769011,2
    F--88422119(+) AGTGTC/TGACCT 1 -- ds50011Minor allele frequency- T:0.08NA 120
    rs1404466151,2
    --88422313(+) TCCTGC/TAGATC 1 -- ds50010--------
    rs2010694261,2
    --88422317(+) CAGAT-/CTAG  
            
    CTAGC
    1 -- ds50010--------
    rs744955611,2
    --88422352(+) ACCTGG/TGTGTG 1 -- ds50013Minor allele frequency- T:0.32CSA WA 123
    rs29198671,2
    C,F,O,H--88422412(+) GTGTGG/AATCAT 1 -- ds500120Minor allele frequency- A:0.34NS EA NA WA 3976
    rs1455561051,2
    --88422427(+) ATTATC/TAACAT 1 -- ds50010--------
    rs1380278071,2
    C,F--88422571(+) GACTTG/CTTTAA 1 -- ut311Minor allele frequency- C:0.00NA 4484
    rs1119791641,2
    --88422757(+) AAATTC/TGTCTG 1 -- int12Minor allele frequency- T:0.05CSA WA 121

    HapMap Linkage Disequilibrium report for FABP1 (88422510 - 88427635 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for FABP1: --
    Human Gene Mutation Database (HGMD): FABP1

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    FABP1 for disorders           About GeneDecksing

    OMIM gene information: 134650    OMIM disorders: --

    20/37 diseases for FABP1 (see all 37):    About MalaCards
    focal glomerulosclerosis    ureteral obstruction    anderson disease    fatty liver disease
    polycystic kidney disease    liver disease    glomerulosclerosis    colonic polyps
    insulin resistance    proteinuria    kidney disease    renal cell carcinoma
    cerebral infarction    nephropathy    hepatocellular carcinoma    colorectal cancer
    acute pancreatitis    prostate cancer    breast cancer    kidney cancer

    10/26 Novoseek disease relationships for FABP1 gene (see all 26)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    fatty liver 90.7 200 15138477 (5), 1699834 (5), 2164578 (2), 1711781 (2) (see all 99)
    renal disease 52.2 40 16490622 (6), 12707994 (3), 14749682 (3), 16860300 (3) (see all 16)
    chronic glomerulonephritis 42.5 5 16118482 (1), 16234607 (1), 16249547 (1)
    proteinuria 33.1 6 16118482 (2), 19666118 (2), 17954367 (1), 18855269 (1)
    diabetic nephropathies 32.3 16 19390215 (3), 19912308 (2), 19481229 (2), 16249547 (2) (see all 5)
    colorectal cancer 27.2 20 10518104 (7), 15138477 (3), 16489072 (1), 2127610 (1)
    microalbuminuria 27.1 3 16236942 (1), 16506273 (1)
    hepatocellular carcinoma 22.7 10 17425983 (2), 2164578 (1), 1699834 (1)
    liver damage 22.1 3 15696188 (1), 12406996 (1)
    malabsorption 21.1 2 17605029 (2)

    Genetic Association Database (GAD): FABP1
    Human Genome Epidemiology (HuGE) Navigator: FABP1 (14 documents)

    Export disorders for FABP1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for FABP1 gene, integrated from 9 sources (see all 243):
    (articles sorted by number of sources associating them with FABP1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. A Thr94Ala mutation in human liver fatty acid-binding protein contributes to reduced hepatic glycogenolysis and blunted elevation of plasma glucose levels in lipid-exposed subjects. (PubMed id 17698986)1, 3, 9 Weickert M.O....Mohlig M. (2007)
    2. Effect of liver fatty acid binding protein (FABP) T94A missense mutation on plasma lipoprotein responsiveness to treatment with fenofibrate. (PubMed id 15249972)1, 4, 9 Brouillette C....Vohl M.C. (2004)
    3. Plasma concentrations of apolipoprotein B are modulated by a gene--diet interaction effect between the LFABP T94A polymorphism and dietary fat intake in French-Canadian men. (PubMed id 15308127)1, 4, 9 Robitaille J....Vohl M.C. (2004)
    4. Intestinal fatty acid binding protein and microsomal triglyceride transfer protein polymorphisms in French-Canadian youth. (PubMed id 15547295)1, 4 Stan S....Levy E. (2005)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Human liver fatty acid binding protein gene is located on chromosome 2. (PubMed id 3012800)1, 3 Chen S.H....Chan L. (1986)
    7. Human liver fatty acid binding protein cDNA and amino acid sequence. Functional and evolutionary implications. (PubMed id 3838309)1, 2 Chan L.... Smith L.C. (1985)
    8. Human liver fatty acid binding protein. Isolation of a full length cDNA and comparative sequence analyses of orthologous and paralogous proteins. (PubMed id 3838313)1, 2 Lowe J.B....Gordon J.I. (1985)
    9. Expression of liver fatty acid binding protein alters growth and differentiation of embryonic stem cells. (PubMed id 11354243)1, 9 Schroeder F....Kier A.B. (2001)
    10. Antioxidative function of L-FABP in L-FABP stably transfected Chang liver cells. (PubMed id 16175609)1, 9 Wang G....Burczynski F.J. (2005)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 2168 HGNC: 3555 AceView: FABP1 Ensembl:ENSG00000163586 euGenes: HUgn2168
    ECgene: FABP1 Kegg: 2168 H-InvDB: FABP1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for FABP1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for FABP1 gene:
    Search GeneIP for patents involving FABP1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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