Aliases for FABP1 Gene
External Ids for FABP1 Gene
Previous GeneCards Identifiers for FABP1 Gene
This gene encodes the fatty acid binding protein found in liver. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. This protein and FABP6 (the ileal fatty acid binding protein) are also able to bind bile acids. It is thought that FABPs roles include fatty acid uptake, transport, and metabolism. [provided by RefSeq, Mar 2011]
GeneCards Summary for FABP1 Gene
FABP1 (Fatty Acid Binding Protein 1) is a Protein Coding gene. Diseases associated with FABP1 include Hepatocellular Adenoma and Membranous Nephropathy. Among its related pathways are PPAR signaling pathway and Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha). GO annotations related to this gene include chromatin binding and lipid binding. An important paralog of this gene is FABP6.
UniProtKB/Swiss-Prot for FABP1 Gene
Plays a role in lipoprotein-mediated cholesterol uptake in hepatocytes (PubMed:25732850). Binds cholesterol (PubMed:25732850). Binds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport (By similarity).