F8A1 Gene
protein-coding GIFtS: 44
GC0XP153678
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coagulation factor VIII-associated (intronic transcript) 1
(Previous name: coagulation factor VIII-associated (intronic transcript) )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database
(Previous symbol: F8A)
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Aliases &
Descriptions
for F8A1
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc
, and/or 7Ensembl,
8miRBase)
About This Section
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| Aliases |
|---|
| DXS522E 1, 2 | | F8A 2, 3 | | HAP40 2 |
| | | Descriptions |
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| CpG island protein 3 | | coagulation factor VIII-associated (intronic transcript) 1 | | coagulation factor VIII-associated (intronic transcript) 1 2 | | coagulation factor VIII-associated protein 2 | | factor VIII associated protein 2 | | factor VIII intron 22 protein 2 | | huntingtin-associated protein 40 2 |
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Search outside databases for aliases for F8A1 gene |
Summaries
for F8A1(According to Entrez Gene,
Wikipedia's
Gene Wiki,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| EntrezGene summary for F8A1:
This gene is contained entirely within intron 22 of the factor VIII gene; spans less than 2 kb, and
is transcribed in the direction opposite of factor VIII. A portion of intron 22 (int22h),
containing F8A, is repeated twice extragenically closer to the Xq telomere. Although its function
is unknown, the observation that this gene is conserved in the mouse implies it has some function.
Unlike factor VIII, this gene is transcribed abundantly in a wide variety of cell types. [provided
by RefSeq]
UniProtKB/Swiss-Prot: F8I2_HUMAN, P23610Function: Not known. Possible housekeeping roleGene Wiki entry for F8A1 |
Genomic Location
for F8A1
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to
UCSC and
Ensembl,
Transcription factor binding sites according to
SABiosciences)
About This Section
| Genomic View: UCSC Golden Path with GeneCards custom track
 Transcription factor binding sites upstream to the F8A1 gene 
Entrez Gene cytogenetic band: Xq28 Ensembl cytogenetic band: Xq28 HGNC cytogenetic band: Xq28F8A1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc gene densities for chromosome X GeneLoc Exon Structure GeneLoc location for GC0XP153678:
(about GC identifiers)
Start:
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153,767,829 bp from pter |
End:
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153,769,530 bp from pter |
Size:
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1,702 bases |
Orientation:
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plus strand |
RefSeq DNA sequence:- NC_000023.9 NT_011726.13
| Proteins
for F8A1
(According to
1UniProtKB,
and/or Ensembl,
Phosphorylation sites according to 2Phosphosite,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Enzo Life Sciences,
Abnova,
OriGene and/or,
Abcam,
Biochemical Assays by
Invitrogen,
Millipore,
R&D Systems,
Cell Signaling Technology, and/or
Enzo Life Sciences,
Ontologies according to Gene
Ontology Consortium 01 Apr 2009 and
Entrez Gene,
Antibodies by Invitrogen,
Millipore,
Sigma-Aldrich,
R&D Systems,
Cell Signaling Technology,
Abcam,
Abnova, and/or
Novus Biologicals)
About This Section
| UniProtKB/Swiss-Prot: F8I2_HUMAN, P23610 (See
protein sequence)Recommended Name: Factor VIII intron 22 protein Size: 371 amino acids; 39103 Da
Sequence caution: Sequence=AAA35713.1; Type=Frameshift; Positions=231, 257, 367;
Secondary accessions: Q5HY66 Q8IXP3REFSEQ proteins: NP_036283.2
ENSEMBL proteins: ENSP00000358456
Human Recombinant Proteins  Browse Origene for full length recombinant human proteins expressed in human HEK293 cells
Antibodies for F8A1:
Assays for F8A1: | Protein
Domains/
Families
for F8A1(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
| ProtoNet protein and cluster: P23610 | Gene Function
for F8A1
(According to MGI Jun 06 2009, UniProtKB,
IUBMB,and/or Genatlas,
shRNA from
OriGene,
Sigma-Aldrich, RNAi from
Sigma-Aldrich,
RNAi Products,
Clones, and
Q-PCR Products
from Invitrogen,
Millipore,
OriGene, and/or
Abnova,
siRNAs from
Applied Biosystems,
SYBR primers from OriGene,
Cell-based Assays from Millipore,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012151
 Applied Biosystems Silencer® siRNAs for F8A1
 Sigma-Aldrich siRNA for F8A1
Sigma-Aldrich shRNA for F8A1
Explore Sigma-Aldrich super-pooled esiRNAs
OriGene GFP tagged cDNA clone in CMV expression vector: NM_012151
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012151
untagged cDNA clone in CMV expression vector: NM_012151
Primers:  Browse
Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers
OriGene genome-wide validated SYBR primer pairs: NM_012151
UniProtKB/Swiss-Prot: F8I2_HUMAN, P23610Function: Not known. Possible housekeeping role | Pathways & Interactions
for F8A1
(Pathways according to Invitrogen
(maps by GeneGo),
Millipore,
Cell Signaling Technology,
Sigma-Aldrich,
KEGG
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Proteins Network according to
SABiosciences,
Interactions according to 1UniProtKB,
2MINT, and/or
3STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Apr 2009 via
Entrez Gene.)
About This Section
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Drugs & Compounds
for F8A1(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
Sigma-Aldrich, Tocris Bioscience, and/or
Novoseek and Drugs according to
Enzo Life Sciences and/or
PharmGKB)
About This Section
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 Browse Tocris compounds for F8A1
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Transcripts
for F8A1(GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
non coding RNAs according to
RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from Invitrogen,
Millipore, and/or
Abnova,
siRNAs from Applied Biosystems,
Sigma-Aldrich,
shRNA from
Sigma-Aldrich,
OriGene,
Tagged/untagged cDNA clones from
OriGene,
Expression Assays from Applied Biosystems)
About This Section
| OriGene 29mer shRNA kit in GFP-retroviral vector: NM_012151
Sigma-Aldrich siRNA for F8A1
Sigma-Aldrich shRNA for F8A1
Explore Sigma-Aldrich super-pooled esiRNAs
Applied Biosystems Silencer® siRNAs: NM_012151 REFSEQ mRNAs for F8A1 gene: NM_012151.3
Applied Biosystems TaqMan ® Gene Expression Assays: NM_012151
OriGene GFP tagged cDNA clone in CMV expression vector: NM_012151
Myc/DDK tagged cDNA clone in CMV expression vector: NM_012151
untagged cDNA clone in CMV expression vector: NM_012151
Additional cDNA sequence: BC039693.1 BC071963.1 11 DOTS entries: DT.415840 DT.100779256 DT.91852393 DT.95206260 DT.121312440 DT.121291769 DT.121303787 DT.95156169 DT.100767899 DT.121291737 DT.121291745 1 AceView cDNA sequence:BI752892
 highest scoring ESTs for F8A1:AA280311 AA410983 AA463924 AA464059 AA483781 AA653515 AA909860 AA974217 AA988794 AI143222 Unigene Cluster for F8A1: Coagulation factor VIII-associated (intronic transcript) 1 Hs.533543 [show with all ESTs]Unigene Representative Sequence: BC039693
GeneLoc Exon Structure
1 Ensembl transcript including schematic representation: ENST00000369446
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Expression
for F8A1
(Experimental results according to
1GeneNote
and GNF BioGPS,
probe sets-to-genes annotations according to
2GeneAnnot ,
3GeneTide ,
Sets of similar genes according to GeneDecks,
Electronic Northern calculations according to data from
UniGene (Build 219 Homo sapiens),
SAGE tags according to
CGAP,
plus additional links to
SOURCE, and/or
GNF
BioGPS, and/or
EXPOLDB, and/or
UniProtKB,
Expression Assays from
Applied Biosystems
)
About This Section
| F8A1 expression in normal and diseased human tissues
Applied Biosystems TaqMan ® Gene Expression Assays for F8A1
1 / 2 / 3 3 probe-sets matching F8A1 gene Data from
(Publications) and GNF BioGPS
About these images
About these images
CGAP SAGE TAG: --
SOURCE GeneReport for Unigene cluster: Hs.533543
Expression variation in blood from EXPOLDB for F8A1 UniProtKB/Swiss-Prot: F8I2_HUMAN, P23610Tissue specificity: Produced abundantly in a wide variety of cell types |
Orthologs
for F8A1
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
and/or
5MGI Jun 06 2009,
with possible further links to
Flybase
and/or
WormBase,
Gene Trees according to Ensembl)
About This Section
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Orthologs for F8A1 gene from 5/8 species (see all 8
)
About this table Species with no ortholog for F8A1
ENSEMBL Gene Tree for F8A1 | Paralogs
for F8A1(Paralogs according to 1HomoloGene
and 2Ensembl, Pseudogenes according to 3Pseudogene.org)
About This Section
| Paralogs for F8A1 gene
- F8A31 2 F8A21 2
Pseudogenes
- 1 related pseudogene
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SNPs/Variants
for F8A1(According to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE, and
UniProtKB,
Linkage Disequilibrium by HapMap,
Genotyping Reagents from
Applied Biosystems)
About This Section
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Disorders & Mutations
for F8A1
(in which this Gene is Involved, According to
OMIM, UniProtKB,
Novoseek, PharmGKB,
Genatlas, GeneTests,
Blood group antigen gene mutations by BGMUT,
HGMD, GAD,
HuGE Navigator,
BCGD,
and/or TGDB.)
About This Section
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OMIM: 305423
1  Novoseek disease relationship for F8A1 gene
| Disease |
Score |
Articles |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| hemophilia a |
79.72 |
1 |
1954778 (1) |
About this table
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Medical News
for F8A1(Possibly Related Articles in
Doctor's Guide)
About This Section
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Publications
for F8A1 (in
PubMed.
Associations of this gene to articles via
1Novoseek,
2HGNC,
3Entrez Gene,
4UniProtKB/Swiss-Prot,
5UniProtKB/TrEMBL,
6GAD, and/or
7PharmGKB)
About This Section
| 10/25 PubMed articles for F8A1 gene (see all 25
): |
Search for F8A1
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing F8A1
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
and/or
H-InvDB)
About This Section
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| Other Databases showing F8A1
(According to HUGE)
About This Section
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Specialized Databases showing F8A1(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| About This Section
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| Services
for F8A1(Reagents available from Applied Biosystems, Antibodies and assays by Cell
Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section
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Products for F8A1:
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| | |  | Search Tocris compounds for F8A1 |
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