Aliases for F8 Gene
Aliases for F8 Gene
External Ids for F8 Gene
- HGNC: 3546
- Entrez Gene: 2157
- Ensembl: ENSG00000185010
- OMIM: 300841
- UniProtKB: P00451
Previous HGNC Symbols for F8 Gene
- F8C
Previous GeneCards Identifiers for F8 Gene
- GC0XM148127
- GC0XM150444
- GC0XM151651
- GC0XM152532
- GC0XM153627
- GC0XM153717
- GC0XM154064
- GC0XM142607
Summaries for F8 Gene
-
This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation; factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. [provided by RefSeq, Jul 2008]
GeneCards Summary for F8 Gene
F8 (Coagulation Factor VIII) is a Protein Coding gene. Diseases associated with F8 include Hemophilia A and Factor Viii Deficiency. Among its related pathways are Formation of Fibrin Clot (Clotting Cascade) and Transport to the Golgi and subsequent modification. GO annotations related to this gene include oxidoreductase activity and copper ion binding. An important paralog of this gene is HEPHL1.
UniProtKB/Swiss-Prot for F8 Gene
-
Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for F8 Gene
Genomics for F8 Gene
Regulatory Elements for F8 Gene
Enhancers for F8 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around F8 on UCSC Golden Path with GeneCards custom track
Promoters for F8 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around F8 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the F8 gene promoter:
Regulatory Element Products
Genomic Location for F8 Gene
- Chromosome:
- X
- Start:
- 154,835,788 bp from pter
- End:
- 155,026,940 bp from pter
- Size:
- 191,153 bases
- Orientation:
- Minus strand
Genomic View for F8 Gene
Genes around F8 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- Xq28 by Ensembl
- Xq28 by Entrez Gene
- Xq28 by HGNC
F8 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for F8 Gene
Proteins for F8 Gene
-
Protein details for F8 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P00451-FA8_HUMAN
- Recommended name:
- Coagulation factor VIII
- Protein Accession:
- P00451
- Q14286
- Q5HY69
Protein attributes for F8 Gene
- Size:
- 2351 amino acids
- Molecular mass:
- 267009 Da
- Quaternary structure:
-
- Interacts with VWF/vWF. vWF binding is essential for the stabilization of F8 in circulation.
Three dimensional structures from OCA and Proteopedia for F8 Gene
Protein Expression for F8 Gene
Post-translational modifications for F8 Gene
- Sulfation on Tyr-1699 is essential for binding vWF.
- Glycosylation at Asn 60, Asn 258, Asn 601, Asn 776, Asn 803, Asn 847, Asn 919, Asn 962, Asn 982, Asn 1020, Asn 1024, Asn 1074, Asn 1085, Asn 1204, Asn 1274, Asn 1278, Asn 1301, Asn 1319, Asn 1431, Asn 1461, Asn 1829, and Asn 2137
- Modification sites at PhosphoSitePlus
Other Protein References for F8 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- EMD Millipore Complete listing of Mono and Polychlonal Antibodies for F8
- Novus Biologicals Antibodies for F8
- Abcam antibodies for Factor VIII + VIII A2domain
-
Cloud-Clone Corp. Antibodies for F8
- Invitrogen Antibodies for F8
- antibodies-online Antibodies for F8: See all 267
- GeneTex F8 antibody for F8
-
Santa Cruz Biotechnology (SCBT) Antibodies for F8
- Factor VIII (E-16)
- Factor VIII (F-15)
- Factor VIII (D-15)
- Factor VIII heavy chain (H-140)
- Factor VIII light chain (H-100)
- Factor VIII (012)
- Factor VIII (102)
- Factor VIII light chain (RFFVIII C/5)
- Factor VIII (RFFVIIIC/8)
- Factor VIII (GMA-012)
- Factor VIII (GMA-8001)
- Factor VIII (GMA-8002)
- Factor VIII (GMA-8011)
- Factor VIII (R8B12)
- Factor VIII (H-19)
Protein Products
-
OriGene Purified Proteins for F8
- Search Origene for MassSpec and Protein Over-expression Lysates for F8
- Origene Custom Protein Services for F8
- ProSpec Recombinant Proteins for F8
-
Cloud-Clone Corp. Proteins for F8
- antibodies-online Proteins for F8: See all 31
- Search antibodies-online for peptides
- Search GeneTex for Proteins for F8
No data available for DME Specific Peptides for F8 Gene
Domains & Families for F8 Gene
Protein Domains for F8 Gene
Suggested Antigen Peptide Sequences for F8 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P00451UniProtKB/Swiss-Prot:
FA8_HUMAN :- Domain F5/8 type C 2 is responsible for phospholipid-binding and essential for factor VIII activity.
- Belongs to the multicopper oxidase family.
- Domain:
-
- Domain F5/8 type C 2 is responsible for phospholipid-binding and essential for factor VIII activity.
- Contains 3 F5/8 type A domains.
- Contains 2 F5/8 type C domains.
- Contains 6 plastocyanin-like domains.
- Family:
-
- Belongs to the multicopper oxidase family.
No data available for Gene Families for F8 Gene
Function for F8 Gene
Molecular function for F8 Gene
- UniProtKB/Swiss-Prot Function:
- Factor VIII, along with calcium and phospholipid, acts as a cofactor for F9/factor IXa when it converts F10/factor X to the activated form, factor Xa.
Phenotypes for F8 Gene
- MGI mutant phenotypes for F8:
- inferred from 3 alleles
- GenomeRNAi human phenotypes for F8:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
-
ViGene Biosciences lentiviral particle packaged cDNA for F8 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for F8 gene
- Search ViGene Biosciences for F8
CRISPR Products
-
OriGene CRISPR knockouts for F8
-
Santa Cruz Biotechnology (SCBT) CRISPR for F8
- GenScript: Design CRISPR guide RNA sequences for F8
miRNA Products
- Search ViGene Biosciences for F8
Clone Products
- OriGene clones in human for F8
- OriGene ORF clones in human,rat for F8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for F8
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for F8 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for F8 gene
-
ViGene Biosciences ready-to-package AAV shRNAs for F8 gene
Flow Cytometry Products
No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , miRNA , Transcription Factor Targets and HOMER Transcription for F8 Gene
Localization for F8 Gene
Subcellular locations from UniProtKB/Swiss-Prot for F8 Gene
- Secreted, extracellular space.
| Compartment | Confidence |
|---|---|
| endoplasmic reticulum | 5 |
| extracellular | 5 |
| golgi apparatus | 4 |
| plasma membrane | 4 |
| lysosome | 1 |
| mitochondrion | 1 |
| vacuole | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005788 | endoplasmic reticulum lumen | TAS | -- |
| GO:0033116 | endoplasmic reticulum-Golgi intermediate compartment membrane | TAS | -- |
Pathways & Interactions for F8 Gene
More details on SuperPathways for F8Pathways by source for F8 Gene
2 BioSystems pathways for F8 Gene
16 Reactome pathways for F8 Gene
1 KEGG pathway for F8 Gene
1 R&D Systems pathway for F8 Gene
2 Qiagen pathways for F8 Gene
Interacting Proteins for F8 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006953 | acute-phase response | IEA | -- |
| GO:0007596 | blood coagulation | TAS | -- |
| GO:0007597 | blood coagulation, intrinsic pathway | TAS | -- |
| GO:0018279 | protein N-linked glycosylation via asparagine | TAS | -- |
| GO:0043687 | post-translational protein modification | TAS | -- |
No data available for SIGNOR curated interactions for F8 Gene
Drugs & Compounds for F8 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Drotrecogin alfa | Approved, Investigational, Withdrawn | Pharma | inhibitor, Target, multitarget | 0 | ||
| Coagulation Factor IX | Approved | Pharma | Target, cofactor | 0 | ||
| Methotrexate | Approved | Pharma | Folate antagonist,inhibits DFHR, Cytotoxic agent | 1466 | ||
| Folic Acid | Approved | Nutra | 4079 | |||
| calcium | Nutra | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Transcripts for F8 Gene
mRNA/cDNA for F8 Gene
- (3) REFSEQ mRNAs :
- (18) Additional mRNA sequences :
- (86) Selected AceView cDNA sequences:
- (5) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for F8 Gene
CRISPR Products
-
OriGene CRISPR knockouts for F8
-
Santa Cruz Biotechnology (SCBT) CRISPR for F8
- GenScript: Design CRISPR guide RNA sequences for F8
miRNA Products
- Search ViGene Biosciences for F8
Clone Products
- OriGene clones in human for F8
- OriGene ORF clones in human,rat for F8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for F8
Flow Cytometry Products
Expression for F8 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Endothelium (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for F8 Gene
This gene is overexpressed in Heart - Left Ventricle (x4.8) and Heart - Atrial Appendage (x4.4).
This gene is overexpressed in Serum (28.9), Plasma (19.0), and Retina (8.8).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for F8 Gene
SOURCE GeneReport for Unigene cluster for F8 Gene Hs.632836
Primer Products
-
OriGene qPCR primer pairs for F8
-
OriGene qPCR primer pairs and template standards for F8
No data available for mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for F8 Gene
Orthologs for F8 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | F8 35 |
|
||
| F8 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | F8 35 |
|
||
| F8 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | F8 35 |
|
||
| F8 16 |
|
||||
| F8 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | F8 35 |
|
||
| F8 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | F8 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | F8 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | F8 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | F8 36 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | F8 36 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | f8 36 |
|
OneToOne | |
| sea squirt (Ciona savignyi) |
Ascidiacea | CSA.2640 36 |
|
OneToMany |
- Species with no ortholog for F8:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Paralogs for F8 Gene
(11) SIMAP similar genes for F8 Gene using alignment to 52 proteins:
- FA8_HUMAN
- A0A2G2_HUMAN
- A0A2G3_HUMAN
- A0A2G4_HUMAN
- A0A2G5_HUMAN
- A0A2G6_HUMAN
- A0A2G8_HUMAN
- A0A2G9_HUMAN
- A0FJ18_HUMAN
- A0FJ19_HUMAN
- A0FJ20_HUMAN
- A5JQJ5_HUMAN
- A5JQJ6_HUMAN
- A5JQJ7_HUMAN
- A5JQJ8_HUMAN
- A5JQJ9_HUMAN
- A6NAE5_HUMAN
- A6NAE6_HUMAN
- A6NAE8_HUMAN
- A6NAE9_HUMAN
- A6NAF0_HUMAN
- A6NAF1_HUMAN
- A6NAF3_HUMAN
- B1B0G8_HUMAN
- B1B0G9_HUMAN
- D5H408_HUMAN
- E3VWA2_HUMAN
- E3VWA3_HUMAN
- E3VWA4_HUMAN
- E3VWA5_HUMAN
- E3VWA6_HUMAN
- F2WWL4_HUMAN
- F8UV73_HUMAN
- G8GEI5_HUMAN
- Q003U9_HUMAN
- Q003V0_HUMAN
- Q003V1_HUMAN
- Q003V2_HUMAN
- Q003V3_HUMAN
- Q003V4_HUMAN
- Q003V5_HUMAN
- Q003V6_HUMAN
- Q003V7_HUMAN
- Q003V8_HUMAN
- Q003V9_HUMAN
- Q003W0_HUMAN
- Q003W2_HUMAN
- Q06DL6_HUMAN
- Q06DL7_HUMAN
- Q06DL8_HUMAN
- Q06DL9_HUMAN
- Q2VF45_HUMAN
Variants for F8 Gene
| SNP ID | Clin | Chr 0X pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| VAR_001045 | Hemophilia A (HEMA) | ||||
| VAR_001046 | Hemophilia A (HEMA) | ||||
| VAR_001047 | Hemophilia A (HEMA) | ||||
| VAR_001048 | Hemophilia A (HEMA) | ||||
| rs1800288 | - | 154,999,520(-) | CACGG(A/T)TCACC | reference, missense |
Residual Variation Intolerance Score:
38.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
4.03;
60.45% of all genes are more intolerant (likely to be disease-causing)
Relevant External Links for F8 Gene
- Human Gene Mutation Database (HGMD)
- F8
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for F8 Gene
Disorders for F8 Gene
(42) MalaCards diseases for F8 Gene - From: OMIM, ClinVar, GeneTests, Orphanet, Swiss-Prot, DISEASES, Novoseek, and GeneCards
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| hemophilia a |
|
|
| factor viii deficiency |
|
|
| severe hemophilia a |
|
|
| mild hemophilia a |
|
|
| moderately severe hemophilia a |
|
|
Search F8 in MalaCards
View complete list of genes associated with diseases
UniProtKB/Swiss-Prot
FA8_HUMAN- Hemophilia A (HEMA) [MIM:306700]: A disorder of blood coagulation characterized by a permanent tendency to hemorrhage. About 50% of patients have severe hemophilia resulting in frequent spontaneous bleeding into joints, muscles and internal organs. Less severe forms are characterized by bleeding after trauma or surgery. {ECO:0000269 PubMed:10215414, ECO:0000269 PubMed:10338101, ECO:0000269 PubMed:10404764, ECO:0000269 PubMed:10408784, ECO:0000269 PubMed:10554831, ECO:0000269 PubMed:10612839, ECO:0000269 PubMed:10691849, ECO:0000269 PubMed:10800171, ECO:0000269 PubMed:10886198, ECO:0000269 PubMed:10896236, ECO:0000269 PubMed:10910910, ECO:0000269 PubMed:10910913, ECO:0000269 PubMed:11298607, ECO:0000269 PubMed:11341489, ECO:0000269 PubMed:11410838, ECO:0000269 PubMed:11442643, ECO:0000269 PubMed:11442647, ECO:0000269 PubMed:11554935, ECO:0000269 PubMed:11748850, ECO:0000269 PubMed:11857744, ECO:0000269 PubMed:11858487, ECO:0000269 PubMed:12195713, ECO:0000269 PubMed:12199686, ECO:0000269 PubMed:12203998, ECO:0000269 PubMed:12325022, ECO:0000269 PubMed:12351418, ECO:0000269 PubMed:12406074, ECO:0000269 PubMed:12614369, ECO:0000269 PubMed:12871415, ECO:0000269 PubMed:12930394, ECO:0000269 PubMed:1301194, ECO:0000269 PubMed:1301932, ECO:0000269 PubMed:1301960, ECO:0000269 PubMed:1349567, ECO:0000269 PubMed:1356412, ECO:0000269 PubMed:15682412, ECO:0000269 PubMed:15810915, ECO:0000269 PubMed:1639429, ECO:0000269 PubMed:16805874, ECO:0000269 PubMed:18184865, ECO:0000269 PubMed:1851341, ECO:0000269 PubMed:1908096, ECO:0000269 PubMed:1908817, ECO:0000269 PubMed:1973901, ECO:0000269 PubMed:2104766, ECO:0000269 PubMed:2105106, ECO:0000269 PubMed:2105906, ECO:0000269 PubMed:2106480, ECO:0000269 PubMed:2107542, ECO:0000269 PubMed:21371196, ECO:0000269 PubMed:2495245, ECO:0000269 PubMed:2498882, ECO:0000269 PubMed:2499363, ECO:0000269 PubMed:2506948, ECO:0000269 PubMed:2510835, ECO:0000269 PubMed:25550078, ECO:0000269 PubMed:26278069, ECO:0000269 PubMed:2833855, ECO:0000269 PubMed:2835904, ECO:0000269 PubMed:3012775, ECO:0000269 PubMed:3122181, ECO:0000269 PubMed:7579394, ECO:0000269 PubMed:7759074, ECO:0000269 PubMed:7794769, ECO:0000269 PubMed:8322269, ECO:0000269 PubMed:8449505, ECO:0000269 PubMed:8639447, ECO:0000269 PubMed:8644728, ECO:0000269 PubMed:8759905, ECO:0000269 PubMed:9029040, ECO:0000269 PubMed:9326186, ECO:0000269 PubMed:9341862, ECO:0000269 PubMed:9450898, ECO:0000269 PubMed:9452104, ECO:0000269 PubMed:9569180, ECO:0000269 PubMed:9569189, ECO:0000269 PubMed:9603440, ECO:0000269 PubMed:9792405, ECO:0000269 PubMed:9829908, ECO:0000269 PubMed:9886318}. Note=The disease is caused by mutations affecting the gene represented in this entry. Of particular interest for the understanding of the function of F8 is the category of CRM (cross-reacting material) positive patients (approximately 5%) that have considerable amount of F8 in their plasma (at least 30% of normal), but the protein is non-functional; i.e. the F8 activity is much less than the plasma protein level. CRM-reduced is another category of patients in which the F8C antigen and activity are reduced to approximately the same level. Most mutations are CRM negative, and probably affect the folding and stability of the protein.
Relevant External Links for F8
No data available for Genatlas for F8 Gene
Publications for F8 Gene
- Characterization of the polypeptide composition of human factor VIII:C and the nucleotide sequence and expression of the human kidney cDNA. (PMID: 3935400) Truett M.A. … Ezban M. (DNA 1985) 2 3 4 67
- Trp2313-His2315 of factor VIII C2 domain is involved in membrane binding: structure of a complex between the C2 domain and an inhibitor of membrane binding. (PMID: 20089867) Liu Z. … Huang M. (J. Biol. Chem. 2010) 3 23
- Endothelial cell processing and alternatively spliced transcripts of factor VIII: potential implications for coagulation cascades and pulmonary hypertension. (PMID: 20174619) Shovlin C.L. … Mauri F.A. (PLoS ONE 2010) 3 23
- Structural investigation of zymogenic and activated forms of human blood coagulation factor VIII: a computational molecular dynamics study. (PMID: 20184747) Venkateswarlu D. (BMC Struct. Biol. 2010) 3 23
- The influence of von Willebrand factor on factor VIII activity measurements. (PMID: 18983499) Butenas S. … Mann K.G. (J. Thromb. Haemost. 2009) 3 23
Products for F8 Gene
- Browse R&D Systems for Antibodies
- Browse R&D Systems for Human Recombinant Proteins
- Browse R&D Systems for biochemical assays
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
- Browse Immunoprecipitation Assays
- Browse Luminex Assays
- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- OriGene Purified Proteins for F8
- Search Origene for MassSpec and Protein Over-expression Lysates for F8
- Origene Custom Protein Services for F8
- Origene siRNA, shRNA, mouse_rna, rat_shrna, and RNAi products in human, mouse, rat for F8
- Browse OriGene Inhibitory RNA Products For F8
- OriGene qPCR primer pairs for F8
- OriGene qPCR primer pairs and template standards for F8
- OriGene CRISPR knockouts for F8
- OriGene clones in human for F8
- OriGene ORF clones in human,rat for F8
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- GenScript: Next-day shipping cDNA clones in your preferred vector
- GenScript Custom Purified and Recombinant Proteins Services for F8
- GenScript Custom Assay Services for F8
- GenScript Custom overexpressing Cell Line Services for F8
- GenScript: Design CRISPR guide RNA sequences for F8
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for F8
- Novus Biologicals Antibodies for F8
- Novus Biologicals proteins and lysates for F8
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- ProSpec Recombinant Proteins for F8
- Cloud-Clone Corp. Antibodies for F8
- Cloud-Clone Corp. Proteins for F8
- Cloud-Clone Corp Assay Kits for F8
- Addgene plasmids for F8
- antibodies-online Antibodies for F8: See all 267
- antibodies-online Kits for F8: See all 38
- antibodies-online Proteins for F8: See all 31
- Search antibodies-online for peptides
- GeneTex F8 antibody for F8
- Search GeneTex for Proteins for F8
- ViGene Biosciences adenoviral particle packaged cDNA for F8 gene
- ViGene Biosciences lentiviral particle packaged cDNA for F8 gene
- ViGene Biosciences lentiviral particle packaged cDNA for F8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for F8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for F8 gene
- ViGene Biosciences ready-to-package AAV shRNAs for F8 gene
- Search ViGene Biosciences for F8
- Search ViGene Biosciences for F8
- Santa Cruz Biotechnology (SCBT) Antibodies for F8
- Factor VIII (H-19)
- Factor VIII (E-16)
- Factor VIII (F-15)
- Factor VIII (D-15)
- Factor VIII heavy chain (H-140)
- Factor VIII light chain (H-100)
- Factor VIII (012)
- Factor VIII (102)
- Factor VIII light chain (RFFVIII C/5)
- Factor VIII (RFFVIIIC/8)
- Factor VIII (GMA-012)
- Factor VIII (GMA-8001)
- Factor VIII (GMA-8002)
- Factor VIII (GMA-8011)
- Factor VIII (R8B12)
- Search Santa Cruz Biotechnology (SCBT) for F8 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for F8
Sources for F8 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
- (68) R&D Systems
- (69) Salk
- (70) TGDB
- (71) Tufts
- (72) YEDA
- (73) CROW21
- (74) Tocris
- (75) Abcam
- (76) Novus
- (77) ProSpec
- (78) Sino Biological
- (79) GenScript
- (80) Qiagen
- (81) Cloud-Clone Corp.
- (82) Enzo Life Sciences
- (83) OCA
- (84) Proteopedia
- (85) MOPED
- (86) SPIRE
- (87) neXtProt
- (88) Reactome
- (89) GeneGo (Thomson Reuters)
- (90) fRNAdb
- (91) DISEASES
- (92) SIMAP
- (93) GenomeRNAi
- (94) LifeMap
- (95) miRTarBase
- (96) MalaCards
- (97) Invitrogen
- (98) BitterDB
- (99) Vector BioLabs
- (100) ESI-BIO
- (101) RefSeq
- (102) BioSystems
- (103) MaxQB
- (104) IUPHAR
- (105) BioGPS
- (106) Illumina
- (107) COMPARTMENTS
- (108) HOMER
- (109) PaxDb
- (110) ApexBio
- (111) Addgene
- (112) Advanced Cell Diagnostics
- (113) antibodies-online
- (114) CYP
- (115) NONCODE
- (116) SwitchGear Genomics
- (117) TreeFam
- (118) PathCards
- (119) GeneReviews
- (120) GeneTex
- (121) Taconic Biosciences
- (122) GTEx
- (123) ProteomicsDB
- (124) SCBT
- (125) DGIdb
- (126) ClinicalTrials
- (127) FDA Approved Drugs
- (128) RVIS
- (129) SIGNOR
- (130) diseasecard
- (131) NIH Rare Diseases
- (132) Orphanet
- (133) UMLS
- (134) GTR
- (135) Disease Ontology
- (136) Genetics Home Reference
- (137) MeSH
- (138) MedlinePlus
- (139) CDC
- (140) NINDS
- (141) NCBI Bookshelf
- (142) ClinVar
- (143) Gene Damage Index
- (144) ViGene Biosciences
- (145) HPO
- (146) UDN
- (147) VISTA
- (148) FANTOM5
- (149) ENCODE
- (150) ProSci
- (151) Horizon