Aliases for EXTL2 Gene
External Ids for EXTL2 Gene
Previous GeneCards Identifiers for EXTL2 Gene
GeneCards Summary for EXTL2 Gene
EXTL2 (Exostosin-Like Glycosyltransferase 2) is a Protein Coding gene. Diseases associated with EXTL2 include hereditary multiple exostoses and mucopolysaccharidoses. Among its related pathways are Metabolism and heparan sulfate biosynthesis. GO annotations related to this gene include transferase activity, transferring hexosyl groups and alpha-1,4-N-acetylgalactosaminyltransferase activity. An important paralog of this gene is EXT2.
UniProtKB/Swiss-Prot for EXTL2 Gene
Glycosyltransferase required for the biosynthesis of heparan-sulfate and responsible for the alternating addition of beta-1-4-linked glucuronic acid (GlcA) and alpha-1-4-linked N-acetylglucosamine (GlcNAc) units to nascent heparan sulfate chains.