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EXOSC5 Gene

protein-coding GIFtS: 56

GC19M046586

exosome component 5
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
About This Section

Aliases
CML28 ^³
EC 3.1.13.- ^³
MGC111224 ^²
MGC12901 ^¹, ²
RRP41B ^¹, ²
RRP46 ^¹, ², ³
Rrp46p ^¹, ²
hRrp46p ^¹, ²
p12B ^¹, ², ³

Descriptions
Chronic myelogenous leukemia tumor antigen 28 ^³
Ribosomal RNA-processing protein 46 ^³
exosome component 5 ^², ³
exosome component Rrp46 ^²

External Ids
HGNC: 24662¹
Entrez Gene: 56915²
UniProtKB: Q9NQT4³
Ensembl: ENSG00000077348⁷

Search outside databases for aliases for EXOSC5 gene

Previous GC identifer: GC19M046585

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: EXOS5_HUMAN, Q9NQT4

Function: Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades

inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions.

Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease

activity

Gene Wiki entry for EXOSC5 (Exosome_component_5)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the EXOSC5 gene

Entrez Gene cytogenetic band: 19q13.1 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.1

EXOSC5 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 19 GeneLoc Exon Structure

GeneLoc location for GC19M046586: (about GC identifiers)

Start:	46,584,115 bp from pter
End:	46,595,096 bp from pter
Size:	10,982 bases
Orientation:	minus strand

RefSeq DNA sequence:

NC_000019.8 NT_011109.15

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
About This Section

UniProtKB/Swiss-Prot: EXOS5_HUMAN, Q9NQT4 (See protein sequence)

Recommended Name: Exosome complex exonuclease RRP46

Size: 235 amino acids; 25249 Da

Subunit: Component of the exosome multienzyme ribonuclease complex composed of at least 11

proteins: EXOSC1/CSL4, EXOSC2/RRP4, EXOSC3/RRP40, EXOSC4/RRP41, EXOSC5/RRP46, EXOSC6/MTR3,

EXOSC7/RRP42, EXOSC8/RRP43, EXOSC9/Scl-75, DIS3/RRP44, and EXOSC10/Scl-100 (only in the nuclear

complex). Also associated with the GTPase Ran. Interacts directly with EXOSC1

Subcellular location: Nucleus, nucleolus

PDB structures from and Proteopedia :

2NN6 (3D)

Secondary accessions: Q32Q81 Q8NG16 Q96I89

Post-translational modifications:

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_064543.3

ENSEMBL proteins:

ENSP00000221233

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (EXOSC5)
	Human Recombinant Proteins from Abnova (EXOSC5)

Browse Origene for full length recombinant human proteins expressed in human HEK293 cells

4 Gene Ontology (GO) cellular component terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000178	exosome (RNase complex)	IEA	--
GO:0005634	nucleus	IEA	--
GO:0005730	nucleolus	NAS	11110791
GO:0005737	cytoplasm	NAS	11110791

About this table

Antibodies for EXOSC5:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for EXOSC5
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (EXOSC5), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (EXOSC5)
	Novus Biologicals Antibodies for EXOSC5

Assays for EXOSC5:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

Graphical View of Domain Structure for InterPro Entry Q9NQT4

ProtoNet protein and cluster: Q9NQT4

UniProtKB/Swiss-Prot: EXOS5_HUMAN, Q9NQT4

Similarity: Belongs to the RNase PH family

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EXOSC5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EXOSC5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020158

Applied Biosystems Silencer® siRNAs for EXOSC5

Sigma-Aldrich siRNA for EXOSC5

Sigma-Aldrich shRNA for EXOSC5

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Invitrogen Clones for EXOSC5
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_020158
Myc/DDK tagged cDNA clone in CMV expression vector: NM_020158
untagged cDNA clone in CMV expression vector: NM_020158

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_020158

UniProtKB/Swiss-Prot: EXOS5_HUMAN, Q9NQT4

Function: Component of the exosome 3'->5' exoribonuclease complex, a complex that degrades

inherently unstable mRNAs containing AU-rich elements (AREs) within their 3'-untranslated regions.

Required for the 3'-processing of the 7S pre-RNA to the mature 5.8S rRNA. Has a 3'-5' exonuclease

activity

Enzyme Number (IUBMB): EC 3.1.13.-

5 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000175	3'-5'-exoribonuclease activity	NAS	11110791
GO:0003723	RNA binding	IEA	--
GO:0004527	exonuclease activity	IEA	--
GO:0005515	protein binding	IPI	11812149
GO:0016787	hydrolase activity	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
About This Section

5/20 Interacting proteins for EXOSC5 (ENSP00000221233³ Q9NQT4^{1, 2}) via UniProtKB, MINT, and/or STRING (see all 20 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
EXOSC1	Q9Y3B2¹	STRING (score=.999) EBI-371876, EBI-371892
EXOSC10	Q01780¹	STRING (score=.766) EBI-371876, EBI-358236
EXOSC3	Q9NQT5¹	STRING (score=.999) EBI-371876, EBI-371866
EXOSC8	Q96B26¹	STRING (score=.999) EBI-371876, EBI-371922
CDK5RAP1	Q96SZ6¹	EBI-371876, EBI-372956

About this table

2 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006364	rRNA processing	NAS	11110791
GO:0006396	RNA processing	IEA	--

About this table

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for EXOSC5

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (EXOSC5)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (EXOSC5)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_020158

Sigma-Aldrich siRNA for EXOSC5

Sigma-Aldrich shRNA for EXOSC5

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_020158

REFSEQ mRNAs for EXOSC5 gene:

NM_020158.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_020158

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_020158
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_020158
                                 untagged cDNA clone in CMV expression vector: NM_020158

Additional cDNA sequence:

AF281134.1 AF285785.1 AK314941.1 BC007742.2 BC107696.1 CR592651.1 CR600780.1 CR620099.1

CR621752.1

17 DOTS entries:

DT.446730 DT.100697122 DT.100787480 DT.100787486 DT.121460932 DT.100787485 DT.100787479 DT.121461048

DT.121460787 DT.100711453 DT.100787483 DT.121460801 DT.121460897 DT.121461144 DT.40113849 DT.95237655

DT.99997857

24/223 AceView cDNA sequences (see all 223 ):

BE208616 CA945111 CR600780 BX333742 CA444881 AI359994 BM704499 AI264531

AI214223 BG826804 BU557371 BQ101103 CF126342 BU956438 AF281134 CR620099

CR621752 AI700402 BG396350 AI078748 BE619128 BM671643 AA448983 BX462406

highest scoring ESTs for EXOSC5:

AF281134 AF285785 AI971527 AW249169 AW674475 BC007742 BE253841 BE275615 BE388544 BE619645

Unigene Cluster for EXOSC5:

Exosome component 5

Hs.283741 [show with all ESTs]

Unigene Representative Sequence: BM450105

GeneLoc Exon Structure

4 Alternative Splicing Database (ASD) splice patterns (SP) for EXOSC5

ExUns:	1a	·	1b	·	1c	·	1d	^	2	^	3a	·	3b	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b
SP1:													-
SP2:									-				-
SP3:											-		-		-
SP4:

About this scheme

ECgene alternative splicing isoforms for EXOSC5

1 Ensembl transcript including schematic representation:

ENST00000221233

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

EXOSC5 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for EXOSC5

¹ / ² / ³

3 probe-sets matching EXOSC5 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
53133_at²^{, 3}	U95-B	2	1.00	0.97	1.00	1.00	AI971527	0.80	1.00	0.91	1
218481_at²^{, 3}	U133-A	1	1.00	1.00	--	--	NM_020158	0.60	1.00	0.82	1
218481_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--

GeneDecks EXOSC5 for binary patterns associated with the probe-sets selected above

About GeneDecksing

About this table

Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: GGCTCCTTGA

SOURCE GeneReport for Unigene cluster: Hs.283741
UniProtKB/Swiss-Prot: EXOS5_HUMAN, Q9NQT4
Tissue specificity: Highly expressed in a variety of hematopoietic and epithelial tumor cell lines,
but not in normal hematopoietic tissues or other normal tissue, with the exception of testis

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
About This Section

Orthologs for EXOSC5 gene from 5/17 species (see all 17 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	EXOSC5¹	--	exosome component 5	88.65(n) 93.19(a)	611350 XM_847745.1 XP_852838.1
chimpanzee (Pan troglodytes)	EXOSC5¹	--	exosome component 5	98.87(n) 98.72(a)	740020 XM_001152170.1 XP_001152170.1
rat (Rattus norvegicus)	Exosc5¹	--	exosome component 5	84.54(n) 89.36(a)	308441 XM_218343.2 XP_218343.2
mouse (Mus musculus)	Exosc5^{1, 5}	7 (6.00 cM)⁵	exosome component 5^{1, 5}	84.68(n)¹ 89.36(a)¹	27998¹ NM_138586.2¹ NP_613052.1¹ AA409134⁵ AK006475⁵ (see all 16)
zebrafish (Danio rerio)	Dr.17708²	--	Transcribed sequence with weak similarity to protein more	70.41(n)	BM860267.1

About this table Species with no ortholog for EXOSC5

ENSEMBL Gene Tree for EXOSC5

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
About This Section

Paralogs for EXOSC5 gene

EXOSC4² EXOSC6²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/41 NCBI SNPs in EXOSC5 are shown (see all 41 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 38)

AB	SNP ID	Valid	Chr 19 pos	Sequence	Recs	AA Chg	Type	More	Recs	Allele freq	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--				--
--	rs3826713^1,2	A,C,F	46584109(-)	`TGTCTG/ATTGAG`	1	--	ng5¹		3		NA	116
	rs8103531^1,2	A,C	46583814(+)	`TAGCTC/TGCTGG`	1	--	ng5¹		0	--	--	--	--
	rs10422956^1,2	A,C,F,H	46593101(+)	`TTGCCT/CGAgca`	1	--	int¹		4		EU EA WA	418
	rs878082^1,2	A,C,F,H	46589514(+)	`AGTGAG/AGGTAT`	1	--	int¹		4		EU EA WA	412
	rs7259208^1,2	C,F,H	46586518(+)	`GAGCCG/AATGAG`	1	--	int¹		4		EU EA WA	418
	rs878083^1,2	A,C,F	46589528(+)	`TATCCA/GCCAGG`	1	--	int¹		4		NA EA MN	420
--	rs8105833^1,2	A,C	46587985(+)	`AAGAAA/GTTTCT`	1	--	int¹		0	--	--	--	--
--	rs11667848^1,2	A,C	46592078(+)	`agatcA/Gcacca`	1	--	int¹		0	--	--	--	--
--	rs11667908^1,2	A,C	46591964(+)	`ctaaaA/Gataca`	1	--	int¹		0	--	--	--	--
--	rs7247332^1,2	A,C	46586911(+)	`gtcttC/Gaactc`	1	--	int¹		0	--	--	--	--

About this table

HapMap Linkage Disequilibrium images for EXOSC5 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
About This Section

OMIM: 606492

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
About This Section

10/16 PubMed articles for EXOSC5 gene (see all 16 ):

Protein-protein interactions of hCsl4p with other human exosome subunits. (PubMed id 11812149)^{1, 2, 3, 4} Raijmakers R....Pruijn G.J. (2002)
Three novel components of the human exosome. (PubMed id 11110791)^{2, 3, 4} Brouwer R....Pruijn G.J. (2001)
Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)^{3, 4} Olsen J.V....Mann M. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
CML28 is a broadly immunogenic antigen, which is overexpressed in tumor cells. (PubMed id 12359762)^{3, 4} Yang X.-F.... Ritz J. (2002)
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs. (PubMed id 11719186)^{3, 4} Chen C.Y....Karin M. (2001)
The yeast exosome and human PM-Scl are related complexes of 3'-->5' exonucleases. (PubMed id 10465791)^{3, 4} Allmang C....Mitchell P. (1999)
Activation of cytotoxic T lymphocytes against CML28-bearing tumors by dendritic cells transduced with a recombinant adeno-associated virus encoding the CML28 gene. (PubMed id 18157497)³ Xie L.H....Xie Y. (2008)
Induction of CML28-specific cytotoxic T cell responses using co-transfected dendritic cells with CML28 DNA vaccine and SOCS1 small interfering RNA expression vector. (PubMed id 16815301)³ Zhou H....Huang Z. (2006)
Towards a proteome-scale map of the human protein-protein interaction network. (PubMed id 16189514)³ Rual J.F....Vidal M. (2005)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
About This Section

Entrez Gene: 56915	HGNC: 24662	AceView: EXOSC5	Ensembl:ENSG00000077348	euGenes: HUgn56915
ECgene: EXOSC5	H-InvDB: EXOSC5

(According to HUGE)
About This Section

(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Licensable Technologies for EXOSC5
(Available from WIS Yeda, Salk, Tufts)

About This Section

(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
About This Section

Products for EXOSC5:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for EXOSC5-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for EXOSC5		Antibodies for EXOSC5
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for EXOSC5		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (EXOSC5)
	Antibodies (EXOSC5)
	Chimera RNAi (EXOSC5)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (EXOSC5)
	Antibodies (EXOSC5)

Search OriGene for EXOSC5

Search Tocris compounds for EXOSC5

Search www.enzolifesicences.com for proteins, assays, substrates, inhibitors & antibodies

Antibodies for EXOSC5

GeneCards Homepage - Last full update: 2 Jul 2009 Incremental update: 13 Oct 2009

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Developed at the Crown Human Genome Center & Weizmann Institute of Science

The GeneCards Human Gene Database: Copyright © 1996-2009, Weizmann Institute of Science. All Rights Reserved.
EXOSC5 Gene at Home site.
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server5.xennexinc.com

EXOSC5 Gene

protein-coding GIFtS: 56

Aliases &
Descriptions
for EXOSC5

Summaries
for EXOSC5

Genomic Location
for EXOSC5

Proteins
for EXOSC5

Protein Domains/
Families
for EXOSC5

Gene Function
for EXOSC5

Pathways & Interactions
for EXOSC5

Drugs & Compounds
for EXOSC5

Transcripts
for EXOSC5

Expression
for EXOSC5

Orthologs
for EXOSC5

Paralogs
for EXOSC5

SNPs/Variants
for EXOSC5

Disorders & Mutations
for EXOSC5

Medical News
for EXOSC5

Publications
for EXOSC5

Search for EXOSC5

Genome Databases showing EXOSC5

Other Databases showing EXOSC5

Specialized Databases showing EXOSC5

Licensable Technologies
for EXOSC5

Services
for EXOSC5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

EXOSC5 Gene

protein-coding GIFtS: 56

Aliases & Descriptionsfor EXOSC5

Summariesfor EXOSC5

Genomic Locationfor EXOSC5

Proteinsfor EXOSC5

Protein Domains/Familiesfor EXOSC5

Gene Functionfor EXOSC5

Pathways & Interactionsfor EXOSC5

Drugs & Compoundsfor EXOSC5

Transcriptsfor EXOSC5

Expression for EXOSC5

Orthologsfor EXOSC5

Paralogsfor EXOSC5

SNPs/Variantsfor EXOSC5

Disorders & Mutationsfor EXOSC5

Medical Newsfor EXOSC5

Publicationsfor EXOSC5

Search for EXOSC5

Genome Databases showing EXOSC5

Other Databases showing EXOSC5

Specialized Databases showing EXOSC5

Licensable Technologiesfor EXOSC5

Servicesfor EXOSC5

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for EXOSC5

Summaries
for EXOSC5

Genomic Location
for EXOSC5

Proteins
for EXOSC5

Protein Domains/
Families
for EXOSC5

Gene Function
for EXOSC5

Pathways & Interactions
for EXOSC5

Drugs & Compounds
for EXOSC5

Transcripts
for EXOSC5

Expression
for EXOSC5

Orthologs
for EXOSC5

Paralogs
for EXOSC5

SNPs/Variants
for EXOSC5

Disorders & Mutations
for EXOSC5

Medical News
for EXOSC5

Publications
for EXOSC5

Licensable Technologies
for EXOSC5

Services
for EXOSC5