Aliases for EXOG Gene
External Ids for EXOG Gene
Previous HGNC Symbols for EXOG Gene
Previous GeneCards Identifiers for EXOG Gene
This gene encodes an endo/exonuclease with 5'-3' exonuclease activity. The encoded enzyme catalyzes the hydrolysis of ester linkages at the 5' end of a nucleic acid chain. This enzyme is localized to the mitochondria and may play a role in programmed cell death. Alternatively spliced transcript variants have been described. A pseudogene exists on chromosome 18. [provided by RefSeq, Feb 2009]
GeneCards Summary for EXOG Gene
EXOG (Exo/Endonuclease G) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and endonuclease activity. An important paralog of this gene is ENDOG.
UniProtKB/Swiss-Prot for EXOG Gene
Endo/exonuclease with nicking activity towards supercoiled DNA, a preference for single-stranded DNA and 5-3 exonuclease activity.