Aliases for EXOC6 Gene
External Ids for EXOC6 Gene
Previous HGNC Symbols for EXOC6 Gene
Previous GeneCards Identifiers for EXOC6 Gene
The product of this gene belongs to the SEC15 family. It is highly similar to the protein encoded by Saccharomyces cerevisiae SEC15 gene. This protein is essential for vesicular traffic from the Golgi apparatus to the cell surface in yeast. It is one of the components of a multiprotein complex required for exocytosis. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for EXOC6 Gene
EXOC6 (Exocyst Complex Component 6) is a Protein Coding gene. Among its related pathways are Organelle biogenesis and maintenance and Actin Nucleation by ARP-WASP Complex. An important paralog of this gene is EXOC6B.
UniProtKB/Swiss-Prot for EXOC6 Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Together with RAB11A, RAB3IP, RAB8A, PARD3, PRKCI, ANXA2, CDC42 and DNMBP promotes transcytosis of PODXL to the apical membrane initiation sites (AMIS), apical surface formation and lumenogenesis (By similarity).