Aliases for EXOC5 Gene
External Ids for EXOC5 Gene
Previous HGNC Symbols for EXOC5 Gene
Previous GeneCards Identifiers for EXOC5 Gene
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. [provided by RefSeq, Jul 2008]
GeneCards Summary for EXOC5 Gene
EXOC5 (Exocyst Complex Component 5) is a Protein Coding gene. Diseases associated with EXOC5 include Bardet-Biedl Syndrome 18. Among its related pathways are Insulin Pathway and Cargo trafficking to the periciliary membrane. GO annotations related to this gene include protein N-terminus binding and Ral GTPase binding.
UniProtKB/Swiss-Prot for EXOC5 Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.