Aliases for EXOC1 Gene
External Ids for EXOC1 Gene
Previous HGNC Symbols for EXOC1 Gene
Previous GeneCards Identifiers for EXOC1 Gene
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of the exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]
GeneCards Summary for EXOC1 Gene
EXOC1 (Exocyst Complex Component 1) is a Protein Coding gene. Diseases associated with EXOC1 include commensal bacterial infectious disease. Among its related pathways are Transport to the Golgi and subsequent modification and Arf6 trafficking events. GO annotations related to this gene include phosphatidylinositol-4,5-bisphosphate binding and GTP-Rho binding. An important paralog of this gene is STXBP6.
UniProtKB/Swiss-Prot for EXOC1 Gene
Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.