Aliases for EVX2 Gene
External Ids for EVX2 Gene
Previous GeneCards Identifiers for EVX2 Gene
This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster, which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease resulting in limb malformation. [provided by RefSeq, Sep 2009]
GeneCards Summary for EVX2 Gene
EVX2 (Even-Skipped Homeobox 2) is a Protein Coding gene. Diseases associated with EVX2 include synpolydactyly. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is EVX1.