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EVX2 Gene

protein-coding   GIFtS: 43
GCID: GC02M176908

Even-Skipped Homeobox 2

(Previous names: eve, even-skipped homeobox homolog 2 (Drosophila))
  Search for EVX2
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Even-Skipped Homeobox 21 2
EVX-22 3
Eve, Even-Skipped Homeobox Homolog 2 (Drosophila)1
Eve, Even-Skipped Homeo Box Homolog 22
Even-Skipped Homeo Box 2 (Homolog Of Drosophila Eve)2
Homeobox Even-Skipped Homolog Protein 22

External Ids:    HGNC: 35071   Entrez Gene: 3441912   Ensembl: ENSG000001742797   OMIM: 1429915   UniProtKB: Q038283   

Export aliases for EVX2 gene to outside databases

Previous GC identifers: GC02U990026 GC02M175605 GC02M177147 GC02M176770 GC02M176653 GC02M168822


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for EVX2 Gene:
This gene is located at the 5' end of the HOXD gene cluster on chromosome 2. The encoded protein is a homeobox
transcription factor that is related to the protein encoded by the Drosophila even-skipped (eve) gene, a member
of the pair-rule class of segmentation genes. A 117 kb microdeletion at the 5' end of the HOXD gene cluster,
which includes this gene and the HOXD9-HOXD13 genes, causes synpolydactyly, a dominantly inherited disease
resulting in limb malformation. (provided by RefSeq, Sep 2009)

GeneCards Summary for EVX2 Gene:
EVX2 (even-skipped homeobox 2) is a protein-coding gene. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is GSX1.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the EVX2 gene promoter:
         TBP   PPAR-gamma1   AP-1   ATF-2   c-Jun   PPAR-gamma2   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for EVX2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat EVX2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q31.1   Ensembl cytogenetic band:  2q31.1   HGNC cytogenetic band: 2q31.1

EVX2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EVX2 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M176908:  view genomic region     (about GC identifiers)

Start:
176,942,200 bp from pter      End:
176,948,690 bp from pter
Size:
6,491 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: EVX2_HUMAN, Q03828 (See protein sequence)
Recommended Name: Homeobox even-skipped homolog protein 2  
Size: 476 amino acids; 47800 Da
Developmental stage: Expressed during early embryogenesis and neurogenesis in a biphasic manner

Explore the universe of human proteins at neXtProt for EVX2: NX_Q03828

Explore proteomics data for EVX2 at MOPED


See EVX2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_001073927.1  
ENSEMBL proteins: 
 ENSP00000312385  

EVX2 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
HOXL: Homeoboxes / ANTP class : HOXL subclass

4 InterPro protein domains:
 IPR020479 Homeobox_metazoa
 IPR017970 Homeobox_CS
 IPR001356 Homeobox_dom
 IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry Q03828

ProtoNet protein and cluster: Q03828

1 Blocks protein domain: IPB000047 Lambda and other repressor helix-turn-helix signature

UniProtKB/Swiss-Prot: EVX2_HUMAN, Q03828
Similarity: Belongs to the even-skipped homeobox family
Similarity: Contains 1 homeobox DNA-binding domain


Find genes that share domains with EVX2           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:
     Genatlas biochemistry entry for EVX2:
Drosophila even-skipped pair rule gene homolog 2 (murine Evx2),homeo domain encoding gene,expressed in limbs

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0043565sequence-specific DNA binding IEA--
     
Find genes that share ontologies with EVX2           About GenesLikeMe


Phenotypes:
     8 MGI mutant phenotypes (inferred from 9 alleles(MGI details for Evx2):
 embryogenesis  growth/size/body  limbs/digits/tail  mortality/aging  nervous system 
 no phenotypic analysis  reproductive system  skeleton 

Find genes that share phenotypes with EVX2           About GenesLikeMe

Animal Models:
     MGI mouse knock-outs for EVX2: Evx2/Hoxd13Evx2/tm3.1Ddu Evx2tm1Ddu Evx2/Hoxd13Evx2/tm2Ddu Evx2/Hoxd11/Hoxd12/Hoxd13Evx2/Hoxd11/Hoxd12/tm1Ddu Evx2/Hoxd13Evx2/tm3Ddu Evx2/Hoxd13Evx2/tm1Ddu

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for EVX2
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for EVX2
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for EVX2

miRNA
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Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX2


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
EVX2_HUMAN, Q03828: Nucleus
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005730NOT nucleolus IDA--

Find genes that share ontologies with EVX2           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for EVX2
Interactions:

    Search GeneGlobe Interaction Network for EVX2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for EVX2 (ENSP000003123854) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
InteractantInteraction Details
GeneCardExternal ID(s)
ATN1ENSP000003490764STRING: ENSP00000349076
REREENSP000003386294STRING: ENSP00000338629
ZEB1ENSP000003192484STRING: ENSP00000319248
ZEB2ENSP000003025014STRING: ENSP00000302501
CCNE1ENSP000002626434STRING: ENSP00000262643
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Gene Ontology (GO): 3 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006355regulation of transcription, DNA-templated ----
GO:0008150biological_process ND--
GO:0035108limb morphogenesis IEA--

Find genes that share ontologies with EVX2           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for EVX2



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for EVX2 gene: 
NM_001080458.1  

Unigene Cluster for EVX2:

Even-skipped homeobox 2
Hs.452341  [show with all ESTs]
Unigene Representative Sequence: NM_001080458
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000308618(uc010zeu.2)
miRNA
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Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for EVX2
Predesigned siRNA for gene silencing in human, mouse, rat EVX2
Clone
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OriGene ORF clones in mouse, rat for EVX2
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: EVX2 (NM_001080458)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for EVX2
Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat EVX2
Primer
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Pre-validated RT2 qPCR Primer Assay in human, mouse, rat EVX2
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  QuantiFast Probe-based Assays in human, mouse, rat EVX2

1 DOTS entry:

DT.91921632 

1 AceView cDNA sequence:

BF057568 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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EVX2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATGACGCACG
EVX2 Expression
About this image


EVX2 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 
 Neural Tube (Nervous System)
         Metencephalon
EVX2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

EVX2 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.452341
    Custom PCR Arrays for EVX2
Primer
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OriGene qSTAR qPCR primer pairs in human, mouse for EVX2
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In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX2

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for EVX2 gene from Selected species (see all 12)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Evx21 , 5 even skipped homeotic gene 2 homolog1, 5 86.16(n)1
91.74(a)1
  2 (44.13 cM)5
140291  NM_007967.21  NP_031993.11 
 746529975 
chicken
(Gallus gallus)
Aves EVX21 even-skipped homeobox 2 76.81(n)
72.58(a)
  771375  XM_001234657.3  XP_001234658.3 
lizard
(Anolis carolinensis)
Reptilia EVX26
even-skipped homeobox 2
66(a)
1 ↔ 1
GL343356.1(628378-632437)
tropical clawed frog
(Xenopus tropicalis)
Amphibia evx21 even-skipped homeobox 2 69.42(n)
72.81(a)
  100498260  XM_002935678.2  XP_002935724.2 
zebrafish
(Danio rerio)
Actinopterygii evx22 even-skipped homeobox 2 76.28(n)   30479  NM_131232.1 
fruit fly
(Drosophila melanogaster)
Insecta eve3 blastoderm segmentation specific RNA
polymerase more
71(a)   46C10   --
worm
(Caenorhabditis elegans)
Secernentea vab-76
Protein VAB-7 (vab-7) mRNA, complete cds
33(a)
1 → many
III(10920336-10926041) WBGene00006873


ENSEMBL Gene Tree for EVX2 (if available)
TreeFam Gene Tree for EVX2 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for EVX2 gene
GSX12  HOXA32  MEOX12  HOXA12  HOXB12  HOXB32  HOXD12  HOXA22  
GSX22  EVX12  HOXB22  MEOX22  PDX12  HOXD32  
1 SIMAP similar gene for EVX2 using alignment to 1 protein entry:     EVX2_HUMAN:
EVX1

Find genes that share paralogs with EVX2           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for EVX2 (see all 140)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 2 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1886040671,2
--176339341(+) CGCACA/TGCATC 1 -- ds50010--------
rs8471421,2
C,F--176339626(-) CCGAAG/AGGAAC 1 -- ds50011Minor allele frequency- A:0.07WA 118
rs789382161,2
F--176339697(+) CTCAGG/CGGGCG 1 -- ds50011Minor allele frequency- C:0.06WA 118
rs730299211,2
C,F--176339708(+) CACAGG/AGGACT 1 -- ds50011Minor allele frequency- A:0.14WA 118
rs1998440251,2
--176339727(+) CACTCA/GGAGAG 1 -- ds50010--------
rs2018353661,2
C--176339786(+) GCCTCC/GTCCCT 2 D E mis10--------
rs18681011,2
C,A--176339942(-) ggcggC/Tggtgg 2 G syn1 ese30--------
rs1836772451,2
C--176340106(+) GGCTGC/GCGCGG 2 P A mis10--------
rs2008443471,2
C--176340233(+) CGGAAC/GGTGTC 2 T syn10--------
rs1442291891,2
F--176340348(+) GCAGCG/TGCACG 2 Q P mis11Minor allele frequency- T:0.00NA 2344

HapMap Linkage Disequilibrium report for EVX2 (176942200 - 176948690 bp)

Structural Variations
     Database of Genomic Variants (DGV) 7 variations for EVX2:    About this table    
Variant IDTypeSubtypePubMed ID
nsv520227CNV Loss19592680
nsv875437CNV Loss21882294
dgv4368n71CNV Loss21882294
nsv527187CNV Loss19592680
nsv517968CNV Loss19592680
nsv875438CNV Loss21882294
dgv676n67CNV Gain20364138

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing EVX2
DNA2.0 Custom Variant and Variant Library Synthesis for EVX2

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 142991    OMIM disorders: --

1 disease from the University of Copenhagen DISEASES database for EVX2:
Syndactyly

Find genes that share disorders with EVX2           About GenesLikeMe


Export disorders for EVX2 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for EVX2 gene, integrated from 10 sources (see all 11):
(articles sorted by number of sources associating them with EVX2)
    Utopia: connect your pdf to the dynamic
world of online information

  1. EVX2, a human homeobox gene homologous to the even-skipped segmentation gene, is localized at the 5' end of HOX4 locus on chromosome 2. (PubMed id 1675198)1, 2, 3 D'Esposito M....Boncinelli E. (Genomics 1991)
  2. Generation and annotation of the DNA sequences of human chromosomes 2 and 4. (PubMed id 15815621)1, 2 Hillier L.W.... Wilson R.K. (Nature 2005)
  3. Genome-wide association study of periodontal pathogen colonization. (PubMed id 22699663)1 Divaris K....Offenbacher S. (J. Dent. Res. 2012)
  4. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (amp 2008)
  5. A 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly. (PubMed id 11778160)1 Goodman F.R....Scambler P.J. (Am. J. Hum. Genet. 2002)
  6. NotI flanking sequences: a tool for gene discovery and verification of the human genome. (PubMed id 12136098)1 Kutsenko A.S....Zabarovsky E.R. (Nucleic Acids Res. 2002)
  7. The sequence of the human genome. (PubMed id 11181995)1 Venter J.C.... Zhu X. (Science 2001)
  8. Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31--&gt;q32.1. (PubMed id 11060466)1 Limongi M.Z....Rocchi A. (Cytogenet. Cell Genet. 2000)
  9. Two cases with interstitial deletions of chromosome 2 and sex reversal in one. (PubMed id 10440834)1 Slavotinek A....Kingston H. (Am. J. Med. Genet. 1999)
  10. Localization of the syndactyly type II (synpolydactyly) locus to 2q31 region and identification of tight linkage to HOXD8 intragenic marker. (PubMed id 7581388)1 Sarfarazi M....Sayli B.S. (Hum. Mol. Genet. 1995)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 344191 HGNC: 3507 AceView: LOC344191 Ensembl:ENSG00000174279 euGenes: HUgn344191
ECgene: EVX2 H-InvDB: EVX2

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for EVX2 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for EVX2 gene:
Search GeneIP for patents involving EVX2

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for EVX2  
 Browse OriGene qPCR primer pairs and template standards   Browse OriGene Protein Over-expression Lysates  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for EVX2  
 OriGene qSTAR qPCR primer pairs in human, mouse for EVX2   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for EVX2   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for EVX2   OriGene Custom Protein Services for EVX2  

 
 
 Block miRNA regulation of human, mouse, rat EVX2 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing EVX2
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat EVX2 Predesigned siRNA for gene silencing in human, mouse, rat EVX2
 QuantiFast Probe-based Assays in human, mouse, rat EVX2 QuantiTect SYBR Green Assays in human, mouse, rat EVX2
 Custom PCR Arrays for EVX2 Search Chromatin IP Primers for EVX2
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat EVX2  Search GeneGlobe Interaction Network for EVX2
 Regulatory tfbs in EVX2 promoter
 GenScript Custom Purified and Recombinant Proteins Services for EVX2 GenScript cDNA clones with any tag delivered in your preferred vector for EVX2
 GenScript Custom Assay Services for EVX2 GenScript Custom overexpressing Cell Line Services for EVX2
 CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
 Plasmid Preparation Custom Peptide Services
 Search for Antibodies & Assays

 Search Tocris compounds for EVX2
 Browse Sino Biological Proteins
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 Protein Production Services
 Transfection Reagents
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 EVX2 antibodies
 Antibodies for EVX2
 See all of Abcam's Antibodies, Kits and Proteins for EVX2
 Custom Antibody / Protein Production Service
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 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Proteins for EVX2
 Antibodies for EVX2
 ELISAs for EVX2
 CLIAs for EVX2



 Browse ESI BIO Cell Lines and PureStem Progenitors for EVX2
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX2
 Browse SwitchGear 3'UTR luciferase reporter plasmids for EVX2
 Browse SwitchGear Promoter luciferase reporter plasmids for EVX2
 ThermoFisher Antibodies for EVX2
 Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat EVX2
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for EVX2
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for EVX2
 LSBio Antibodies in human, mouse, rat for EVX2
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
 Browse compounds at ApexBio
 Search Addgene for plasmids for EVX2
  Search eBioscience for proteins for EVX2
  Search eBioscience for elisas for EVX2
  eBioscience FlowRNA Probe Sets
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014 , 21 Aug 2014 , 8 Sep 2014

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