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EVX1 Gene

protein-coding   GIFtS: 48
GCID: GC07P027282

Even-Skipped Homeobox 1

(Previous names: eve, even-skipped homeobox homolog 1 (Drosophila))
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Even-Skipped Homeobox 11 2     Eve, Even-Skipped Homeobox Homolog 12
EVX-12 3     Even-Skipped Homeo Box 1 (Homolog Of Drosophila)2
Eve, Even-Skipped Homeobox Homolog 1 (Drosophila)1     Homeobox Even-Skipped Homolog Protein 12
Eve, Even-Skipped Homeo Box Homolog 12     

External Ids:    HGNC: 35061   Entrez Gene: 21282   Ensembl: ENSG000001060387   OMIM: 1429965   UniProtKB: P496403   

Export aliases for EVX1 gene to outside databases

Previous GC identifers: GC07P026924 GC07P026990 GC07P027024 GC07P027055 GC07P027248 GC07P027165


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for EVX1 Gene:
This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain
closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded
protein may play an important role as a transcriptional repressor during embryogenesis. (provided by RefSeq, Jul
2008)

GeneCards Summary for EVX1 Gene:
EVX1 (even-skipped homeobox 1) is a protein-coding gene. Diseases associated with EVX1 include neuronitis. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is GSX1.

UniProtKB/Swiss-Prot: EVX1_HUMAN, P49640
Function: May play a role in the specification of neuronal cell types




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000007.14  NT_007819.18  NC_018918.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the EVX1 gene promoter:
         Sox5   Lmo2   Nkx2-5   GATA-1   NF-AT   NF-AT4   NF-AT2   NF-AT3   IRF-7A   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): EVX1 promoter sequence
   Search Chromatin IP Primers for EVX1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat EVX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2   Ensembl cytogenetic band:  7p15.2   HGNC cytogenetic band: 7p15.2

EVX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EVX1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P027282:  view genomic region     (about GC identifiers)

Start:
27,282,164 bp from pter      End:
27,290,112 bp from pter
Size:
7,949 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 27,333,351-27,337,379     

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: EVX1_HUMAN, P49640 (See protein sequence)
Recommended Name: Homeobox even-skipped homolog protein 1  
Size: 407 amino acids; 42440 Da
Secondary accessions: A4D199

Explore the universe of human proteins at neXtProt for EVX1: NX_P49640

Explore proteomics data for EVX1 at MOPED


See EVX1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_001980.1  
ENSEMBL proteins: 
 ENSP00000419266   ENSP00000222761   ENSP00000463759   ENSP00000446458  

EVX1 Human Recombinant Protein Products:

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OriGene Protein Over-expression Lysate for EVX1
OriGene Custom MassSpec
OriGene Custom Protein Services for EVX1
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Novus Biologicals EVX1 Lysate
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Browse Sino Biological Cell Lysates
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Cloud-Clone Corp. Proteins for EVX1

EVX1 Antibody Products:

EMD Millipore Mono- and Polyclonal Antibodies for the study of EVX1
Browse R&D Systems for Antibodies
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OriGene Custom Antibody Services for EVX1
Novus Biologicals EVX1 Antibodies
Search for Antibodies for EVX1 at Abcam
Cloud-Clone Corp. Antibodies for EVX1
ThermoFisher Antibodies for EVX1
LSBio Antibodies in human, mouse, rat for EVX1

EVX1 Assay Products:

Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for EVX1
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for EVX1
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for EVX1
Cloud-Clone Corp. CLIAs for EVX1


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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HGNC Gene Families:
HOXL: Homeoboxes / ANTP class : HOXL subclass

4 InterPro protein domains:
 IPR020479 Homeobox_metazoa
 IPR017970 Homeobox_CS
 IPR001356 Homeobox_dom
 IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry P49640

ProtoNet protein and cluster: P49640

1 Blocks protein domain: IPB000047 Lambda and other repressor helix-turn-helix signature

UniProtKB/Swiss-Prot: EVX1_HUMAN, P49640
Similarity: Belongs to the even-skipped homeobox family
Similarity: Contains 1 homeobox DNA-binding domain


EVX1 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: EVX1_HUMAN, P49640
Function: May play a role in the specification of neuronal cell types

     Genatlas biochemistry entry for EVX1:
Drosophila even-skipped pair rule gene homolog 1 (murine Evx1),homeo domain encoding gene

     Gene Ontology (GO): 3 molecular function terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0043565sequence-specific DNA binding IEA--
     
EVX1 for ontologies           About GeneDecksing


Phenotypes:
     4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Evx1):
 embryogenesis  mortality/aging  nervous system  no phenotypic analysis 

EVX1 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Evx1tm1Mrc for EVX1

   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for EVX1
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for EVX1

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for EVX1
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for EVX1

miRNA
Products:
    
Block miRNA regulation of human, mouse, rat EVX1 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate EVX1
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for EVX1
Predesigned siRNA for gene silencing in human, mouse, rat EVX1

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for EVX1

Clone
Products:
     
OriGene clones in human, mouse for EVX1 (see all 7)
OriGene ORF clones in mouse, rat for EVX1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: EVX1 (NM_001989)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for EVX1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EVX1

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for EVX1
Browse ESI BIO Cell Lines and PureStem Progenitors for EVX1 
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX1


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
EVX1_HUMAN, P49640: Nucleus
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5

Gene Ontology (GO): 1 cellular component term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

EVX1 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for EVX1
Interactions:

    Search GeneGlobe Interaction Network for EVX1

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for EVX1 (ENSP000004192664) via UniProtKB, MINT, STRING, and/or I2D (see all 25)
InteractantInteraction Details
GeneCardExternal ID(s)
HSPG2ENSP000003638274STRING: ENSP00000363827
REREENSP000003386294STRING: ENSP00000338629
ATN1ENSP000003490764STRING: ENSP00000349076
ZEB1ENSP000003192484STRING: ENSP00000319248
ZEB2ENSP000003025014STRING: ENSP00000302501
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006355regulation of transcription, DNA-templated ----
GO:0009792embryo development ending in birth or egg hatching IEA--
GO:0021913regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification IEA--
GO:0045944positive regulation of transcription from RNA polymerase II promoter IEA--

EVX1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for EVX1



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for EVX1 gene: 
NM_001989.3  

Unigene Cluster for EVX1:

Even-skipped homeobox 1
Hs.369879  [show with all ESTs]
Unigene Representative Sequence: NM_001989
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000496902(uc003szd.1 uc011jzn.1 uc010kuy.1) ENST00000222761
ENST00000580535 ENST00000518886 ENST00000535619
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat EVX1 using miScript Target Protectors
Search for qRT-PCR Assays for microRNAs that regulate EVX1
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for EVX1
Predesigned siRNA for gene silencing in human, mouse, rat EVX1
Clone
Products:
     
OriGene clones in human, mouse for EVX1 (see all 7)
OriGene ORF clones in mouse, rat for EVX1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: EVX1 (NM_001989)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for EVX1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EVX1
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for EVX1
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat EVX1
  QuantiTect SYBR Green Assays in human, mouse, rat EVX1
  QuantiFast Probe-based Assays in human, mouse, rat EVX1

Additional mRNA sequence: 

AK298822.1 AK299188.1 AK314155.1 X60655.1 

3 DOTS entries:

DT.99998704  DT.92414599  DT.40130881 

14 AceView cDNA sequences:

AI346148 AI215159 AI280183 NM_001989 AI273407 AI733008 AI820879 AA922834 
X60655 AI346582 AI792726 BX103771 AI368067 AI268901 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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EVX1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACGCCCGTGG
EVX1 Expression
About this image


EVX1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 8) fully expand
 
 Primitive Streak (Early Embryonic Tissues)    fully expand to see all 2 entries
         Primitive Streak Cells Posterior Primitive Streak
         Primitive streak-like cells
 
 Epiblast (Early Embryo)    fully expand to see all 2 entries
         Primitive Streak Cells Posterior Primitive Streak
 
 Brain (Nervous System)    fully expand to see all 3 entries
         Thalamus
 
 Neural Tube (Nervous System)    fully expand to see all 2 entries
         Metencephalon
 
 Yolk Sac (Extraembryonic Tissues)
         Definitive Hematopoietic Stem Cells Definitive Yolk Sac
EVX1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

EVX1 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.369879
    Custom PCR Arrays for EVX1
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for EVX1
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat EVX1
QuantiTect SYBR Green Assays in human, mouse, rat EVX1
QuantiFast Probe-based Assays in human, mouse, rat EVX1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals.

Orthologs for EVX1 gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Evx11 , 5 even skipped homeotic gene 1 homolog1, 5 90.01(n)1
94.35(a)1
  6 (25.44 cM)5
140281  NM_007966.41  NP_031992.11 
 523134985 
chicken
(Gallus gallus)
Aves LOC1008593451 homeobox even-skipped homolog protein 1-like 76.95(n)
75.62(a)
  100859345  XM_003640719.2  XP_003640767.1 
lizard
(Anolis carolinensis)
Reptilia EVX16
even-skipped homeobox 1
69(a)
1 ↔ 1
GL343275.1(1240832-1256504)
African clawed frog
(Xenopus laevis)
Amphibia Xl.2772 X.laevis mRNA for Xhox3 homeobox protein, complete more 78.55(n)    D10455.1 
zebrafish
(Danio rerio)
Actinopterygii evx12 even-skipped homeobox 1 76.85(n)   30499  AF305889.1 
fruit fly
(Drosophila melanogaster)
Insecta eve3 blastoderm segmentation specific RNA
polymerase more
60(a)   46C10   --
worm
(Caenorhabditis elegans)
Secernentea vab-76
Protein VAB-7 (vab-7) mRNA, complete cds
35(a)
1 → many
III(10920336-10926041) WBGene00006873


ENSEMBL Gene Tree for EVX1 (if available)
TreeFam Gene Tree for EVX1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for EVX1 gene
GSX12  HOXA32  MEOX12  EVX22  HOXA12  HOXB12  HOXB32  HOXD12  
HOXA22  GSX22  HOXB22  MEOX22  PDX12  HOXD32  
6 SIMAP similar genes for EVX1 using alignment to 4 protein entries:     EVX1_HUMAN (see all proteins):
HOXB1    HOXC13    HOX B6    NKX2-5    EVX2    HOXA4

EVX1 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for EVX1 (see all 146)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs590071911,2
C,F--27280279(+) CCCTAT/AAGAGA 1 -- us2k13Minor allele frequency- A:0.12WA CSA 121
rs1864163831,2
--27280436(+) AAAAGG/TTTCTA 1 -- us2k10--------
rs1892495721,2
--27280453(+) GACTCC/TCCTCA 1 -- us2k10--------
rs8863381,2
F,H--27280455(+) CTCCCC/GTCACT 1 -- us2k14Minor allele frequency- G:0.00MN EA NS 480
rs175017871,2
C,F,H--27280623(+) ATCGTC/GTTAGA 1 -- us2k12Minor allele frequency- G:0.03NS WA 232
rs37576421,2
C,F,H--27280653(+) CCGGAG/ATGAAG 1 -- us2k16Minor allele frequency- A:0.03EA NS 2016
rs1492463651,2
--27280734(+) GGAGAA/GAAGCA 1 -- us2k10--------
rs581579151,2
C--27280779(+) AGAAA-/AGTAGG 1 -- us2k10--------
rs174781541,2
C,F,H--27280809(+) GGTCAC/AGGAAG 1 -- us2k1 tfbs35Minor allele frequency- A:0.04NS EA 538
rs126689641,2
C,H--27280896(+) GCTGCA/C/TTAGGG 1 -- us2k11NA 2

HapMap Linkage Disequilibrium report for EVX1 (27282164 - 27290112 bp)

Structural Variations
     Database of Genomic Variants (DGV) 6 variations for EVX1:    About this table    
Variant IDTypeSubtypePubMed ID
nsv887856CNV Loss21882294
dgv7234n71CNV Loss21882294
dgv7237n71CNV Loss21882294
nsv519583CNV Gain19592680
dgv1094n67CNV Gain20364138
nsv7393OTHER Inversion18451855

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing EVX1
DNA2.0 Custom Variant and Variant Library Synthesis for EVX1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 142996    OMIM disorders: --

1 disease for EVX1:    
About MalaCards
neuronitis


EVX1 for disorders           About GeneDecksing


Export disorders for EVX1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for EVX1 gene integrated from 10 sources:
(articles sorted by number of sources associating them with EVX1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Isolation and mapping of EVX1, a human homeobox gene homologous to even-skipped, localized at the 5' end of HOX1 locus on chromosome 7. (PubMed id 1684419)1, 2, 3, 9 Faiella A.... Gulisano M. (Nucleic Acids Res. 1991)
  2. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (Science 2003)
  3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (Nature 2003)
  4. Transcriptional repression by the human homeobox protein EVX1 in transfected mammalian cells. (PubMed id 7499236)1, 2 Briata P.... Corte G. (J. Biol. Chem. 1995)
  5. Genome-wide association analysis of blood-pressure traits in African-ancestry individuals reveals common associated genes in African and non-African populations. (PubMed id 23972371)1 Franceschini N....Zhu X. (Am. J. Hum. Genet. 2013)
  6. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (Biochem. J. 2012)
  7. EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differentiation by directly repressing GOOSECOID expression. (PubMed id 22178155)1 Kalisz M....Serup P. (Dev. Biol. 2012)
  8. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. (PubMed id 20445134)1 Smith N.L....Vasan R.S. (Circ Cardiovasc Genet 2010)
  9. Toward a complete human genome sequence. (PubMed id 9847074)1 Sulston J.E. and Waterston R. (Genome Res. 1998)
  10. Function of FGF-4 in limb development. (PubMed id 7999365)9 Niswander L....Martin G. (Mol. Reprod. Dev. 1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 2128 HGNC: 3506 AceView: EVX1 Ensembl:ENSG00000106038 euGenes: HUgn2128
ECgene: EVX1 H-InvDB: EVX1

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for EVX1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for EVX1 gene:
Search GeneIP for patents involving EVX1

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 Browse Purified and Recombinant Proteins at EMD Millipore
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 Block miRNA regulation of human, mouse, rat EVX1 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing EVX1
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

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