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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

EVX1 Gene

protein-coding   GIFtS: 48
GCID: GC07P027282

Even-Skipped Homeobox 1

(Previous names: eve, even-skipped homeobox homolog 1 (Drosophila))
  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Even-Skipped Homeobox 11 2     Eve, Even-Skipped Homeobox Homolog 12
EVX-12 3     Even-Skipped Homeo Box 1 (Homolog Of Drosophila)2
Eve, Even-Skipped Homeobox Homolog 1 (Drosophila)1     Homeobox Even-Skipped Homolog Protein 12
Eve, Even-Skipped Homeo Box Homolog 12     

External Ids:    HGNC: 35061   Entrez Gene: 21282   Ensembl: ENSG000001060387   OMIM: 1429965   UniProtKB: P496403   

Export aliases for EVX1 gene to outside databases

Previous GC identifers: GC07P026924 GC07P026990 GC07P027024 GC07P027055 GC07P027248 GC07P027165


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for EVX1 Gene:
This gene encodes a member of the even-skipped homeobox family characterized by the presence of a homeodomain
closely related to the Drosophila even-skipped (eve) segmentation gene of the pair-rule class. The encoded
protein may play an important role as a transcriptional repressor during embryogenesis. (provided by RefSeq, Jul
2008)

GeneCards Summary for EVX1 Gene: 
EVX1 (even-skipped homeobox 1) is a protein-coding gene. Diseases associated with EVX1 include neuronitis. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is MNX1.

UniProtKB/Swiss-Prot: EVX1_HUMAN, P49640
Function: May play a role in the specification of neuronal cell types




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007819.17  NC_018918.2  NT_079592.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the EVX1 gene promoter:
         Sox5   Lmo2   Nkx2-5   GATA-1   NF-AT   NF-AT4   NF-AT2   NF-AT3   IRF-7A   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): EVX1 promoter sequence
   Search SABiosciences Chromatin IP Primers for EVX1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EVX1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7p15.2   Ensembl cytogenetic band:  7p15.2   HGNC cytogenetic band: 7p15.2

EVX1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
EVX1 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P027282:  view genomic region     (about GC identifiers)

Start:
27,282,164 bp from pter      End:
27,290,112 bp from pter
Size:
7,949 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 27,333,351-27,337,379     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: EVX1_HUMAN, P49640 (See protein sequence)
Recommended Name: Homeobox even-skipped homolog protein 1  
Size: 407 amino acids; 42440 Da
Subcellular location: Nucleus
Secondary accessions: A4D199

Explore the universe of human proteins at neXtProt for EVX1: NX_P49640

Explore proteomics data for EVX1 at MOPED 

EVX1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

EVX1 Protein Expression

REFSEQ proteins: NP_001980.1  
ENSEMBL proteins: 
 ENSP00000419266   ENSP00000222761   ENSP00000463759   ENSP00000446458  

Human Recombinant Protein Products for EVX1: 
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Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for EVX1
OriGene Custom MassSpec 
OriGene Custom Protein Services for EVX1
GenScript Custom Purified and Recombinant Proteins Services for EVX1
Novus Biologicals EVX1 Lysate
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for EVX1 

Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--

EVX1 for ontologies           About GeneDecksing



EVX1 Antibody Products: 
EMD Millipore Mono- and Polyclonal Antibodies for the study of EVX1
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Novus Biologicals EVX1 Antibodies
Abcam antibodies for EVX1
Cloud-Clone Corp. Antibodies for EVX1 
ThermoFisher Antibodies for EVX1
LSBio Antibodies in human, mouse, rat for EVX1 

Assay Products for EVX1: 
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Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for EVX1
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for EVX1 
Cloud-Clone Corp. CLIAs for EVX1


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
HOXL: Homeoboxes / ANTP class : HOXL subclass

4 InterPro protein domains:
 IPR020479 Homeobox_metazoa
 IPR017970 Homeobox_CS
 IPR001356 Homeodomain
 IPR009057 Homeodomain-like

Graphical View of Domain Structure for InterPro Entry P49640

ProtoNet protein and cluster: P49640

1 Blocks protein domain: IPB000047 Lambda and other repressor helix-turn-helix signature

UniProtKB/Swiss-Prot: EVX1_HUMAN, P49640
Similarity: Belongs to the even-skipped homeobox family
Similarity: Contains 1 homeobox DNA-binding domain


EVX1 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: EVX1_HUMAN, P49640
Function: May play a role in the specification of neuronal cell types

     Genatlas biochemistry entry for EVX1:
Drosophila even-skipped pair rule gene homolog 1 (murine Evx1),homeo domain encoding gene

     Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003677DNA binding ----
GO:0003700sequence-specific DNA binding transcription factor activity IEA--
GO:0043565sequence-specific DNA binding IEA--
     
EVX1 for ontologies           About GeneDecksing


Phenotypes:
     4 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Evx1):
 embryogenesis  mortality/aging  nervous system  no phenotypic analysis 

EVX1 for phenotypes           About GeneDecksing

Animal Models:
     MGI mouse knock-out Evx1tm1Mrc for EVX1

   inGenious Targeting Laboratory - Custom generated mouse model solutions for EVX1 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for EVX1

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for EVX1 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for EVX1 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat EVX1
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate EVX1
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for EVX1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EVX1

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for EVX1
Sirion Biotech Customized adenovirus for overexpression of EVX1

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for EVX1 (see all 7)
OriGene ORF clones in mouse, rat for EVX1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: EVX1 (NM_001989)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for EVX1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EVX1
Sirion Biotech Customized lentivirus for stable overexpression of EVX1 
                     Customized lentivirus expression plasmids for stable overexpression of EVX1 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for EVX1
Search LifeMap BioReagents cell lines for EVX1
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX1


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section



Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for EVX1

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006355regulation of transcription, DNA-dependent ----
GO:0009792embryo development ending in birth or egg hatching IEA--
GO:0021913regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification IEA--
GO:0045944positive regulation of transcription from RNA polymerase II promoter IEA--

EVX1 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for EVX1

Search CenterWatch for drugs/clinical trials and news about EVX1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for EVX1 gene: 
NM_001989.3  

Unigene Cluster for EVX1:

Even-skipped homeobox 1
Hs.369879  [show with all ESTs]
Unigene Representative Sequence: NM_001989
5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000496902(uc003szd.1 uc011jzn.1 uc010kuy.1) ENST00000222761
ENST00000580535 ENST00000518886 ENST00000535619
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat EVX1
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate EVX1
Browse SwitchGear 3'UTR luciferase reporter plasmids
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for EVX1
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EVX1
Clone
Products:
     
OriGene clones in human, mouse for EVX1 (see all 7)
OriGene ORF clones in mouse, rat for EVX1
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: EVX1 (NM_001989)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for EVX1
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EVX1
Sirion Biotech Customized lentivirus for stable overexpression of EVX1 
                     Customized lentivirus expression plasmids for stable overexpression of EVX1 
Primer
Products:
    
OriGene qSTAR qPCR primer pairs in human, mouse for EVX1
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat EVX1
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EVX1
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EVX1

Additional mRNA sequence: 

AK298822.1 AK299188.1 AK314155.1 X60655.1 

3 DOTS entries:

DT.99998704  DT.92414599  DT.40130881 

14 AceView cDNA sequences:

AI280183 AI346148 NM_001989 AI273407 AI820879 AI215159 AI733008 AI346582 
AI792726 AA922834 X60655 BX103771 AI368067 AI268901 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

EVX1 expression in normal human tissues (normalized intensities)      EVX1 embryonic expression: see
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ACGCCCGTGG
EVX1 Expression
About this image


EVX1 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database 
 5/8 selected tissues (see all 8) fully expand
 
 Brain (Nervous System)    fully expand to see all 9 entries
         Thalamus
         Vomeronasal organ   
 
 Neural Tube (Nervous System)    fully expand to see all 4 entries
         V0 Interneurons pV0 Neural Domain
         Metencephalon
         brain/midbrain/lateral wall   
 
 Spinal Cord (Nervous System)
         Ventral Horn   
 
 Gut Tube (Gastrointestinal Tract)
         Primitive gut tube-like cells ( A scalable, suspension protocol for derivation of...
 
 Primitive Streak (Early Embryonic Tissues)
         Posterior Primitive Streak Cells Posterior Primitive Streak

See EVX1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for EVX1

SOURCE GeneReport for Unigene cluster: Hs.369879
    SABiosciences Custom PCR Arrays for EVX1
Primer
Products:
OriGene qSTAR qPCR primer pairs in human, mouse for EVX1
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat EVX1
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat EVX1
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EVX1
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX1

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for EVX1 gene from 7/14 species (see all 14)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Evx11 , 5 even skipped homeotic gene 1 homolog1, 5 90.01(n)1
94.35(a)1
  6 (25.44 cM)5
140281  NM_007966.41  NP_031992.11 
 523134985 
chicken
(Gallus gallus)
Aves LOC1008593451 homeobox even-skipped homolog protein 1-like 77.69(n)
77.11(a)
  100859345  XM_003640719.1  XP_003640767.1 
lizard
(Anolis carolinensis)
Reptilia EVX16
Uncharacterized protein
68(a)
1 ↔ 1
GL343275.1(1240832-1256504)
African clawed frog
(Xenopus laevis)
Amphibia Xl.2772 X.laevis mRNA for Xhox3 homeobox protein, complete more 78.55(n)    D10455.1 
zebrafish
(Danio rerio)
Actinopterygii evx12 even-skipped homeobox 1 76.85(n)   30499  AF305889.1 
fruit fly
(Drosophila melanogaster)
Insecta eve3 blastoderm segmentation specific RNA
polymerase more
60(a)   46C10   --
worm
(Caenorhabditis elegans)
Secernentea vab-76
Homeobox protein vab-7
30(a)
1 → many
III(10920336-10926041)


ENSEMBL Gene Tree for EVX1 (if available)
TreeFam Gene Tree for EVX1 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for EVX1 gene
MNX12  MEOX12  GBX12  EVX22  MEOX22  GBX22  
6 SIMAP similar genes for EVX1 using alignment to 4 protein entries:     EVX1_HUMAN (see all proteins):
HOXB1    HOXC13    HOX B6    NKX2-5    EVX2    HOXA4

EVX1 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/146 SNPs in EVX1 are shown (see all 146)    About this table     
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 7 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs590071911,2
C,F--27280279(+) CCCTAT/AAGAGA 1 -- us2k13Minor allele frequency- A:0.12WA CSA 121
rs1864163831,2
--27280436(+) AAAAGG/TTTCTA 1 -- us2k10--------
rs1892495721,2
--27280453(+) GACTCC/TCCTCA 1 -- us2k10--------
rs8863381,2
F,H--27280455(+) CTCCCC/GTCACT 1 -- us2k14Minor allele frequency- G:0.00MN EA NS 480
rs175017871,2
C,F,H--27280623(+) ATCGTC/GTTAGA 1 -- us2k12Minor allele frequency- G:0.03NS WA 232
rs37576421,2
C,F,H--27280653(+) CCGGAG/ATGAAG 1 -- us2k16Minor allele frequency- A:0.03EA NS 2016
rs1492463651,2
--27280734(+) GGAGAA/GAAGCA 1 -- us2k10--------
rs581579151,2
C--27280779(+) AGAAA-/AGTAGG 1 -- us2k10--------
rs174781541,2
C,F,H--27280809(+) GGTCAC/AGGAAG 1 -- us2k1 tfbs35Minor allele frequency- A:0.04NS EA 538
rs126689641,2
C,H--27280896(+) GCTGCA/C/TTAGGG 1 -- us2k11NA 2

HapMap Linkage Disequilibrium report for EVX1 (27282164 - 27290112 bp)

Structural Variations
     Database of Genomic Variants (DGV) 6 variations for EVX1:    About this table     
Variant IDTypeSubtypePubMed ID
nsv887856CNV Loss21882294
dgv7234n71CNV Loss21882294
dgv7237n71CNV Loss21882294
nsv519583CNV Gain19592680
dgv1094n67CNV Gain20364138
nsv7393OTHER Inversion18451855

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing EVX1
DNA2.0 Custom Variant and Variant Library Synthesis for EVX1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
OMIM gene information: 142996    OMIM disorders: --

2 diseases for EVX1:    About MalaCards
neuronitis    


EVX1 for disorders           About GeneDecksing


Export disorders for EVX1 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for EVX1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with EVX1)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Isolation and mapping of EVX1, a human homeobox gene homologous to even-skipped, localized at the 5' end of HOX1 locus on chromosome 7. (PubMed id 1684419)1, 2, 3, 9 Faiella A.... Gulisano M. (1991)
  2. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
  3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
  4. Transcriptional repression by the human homeobox protein EVX1 in transfected mammalian cells. (PubMed id 7499236)1, 2 Briata P.... Corte G. (1995)
  5. A cohesin-RAD21 interactome. (PubMed id 22145905)1 Panigrahi A.K....Pati D. (2012)
  6. EVEN-SKIPPED HOMEOBOX 1 controls human ES cell differe ntiation by directly repressing GOOSECOID expression. (PubMed id 22178155)1 Kalisz M....Serup P. (2012)
  7. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospecti ve meta-analysis from the cohorts for heart and aging research in genomic epide miology (CHARGE) consortium. (PubMed id 20445134)1 Smith N.L....Vasan R.S. (2010)
  8. Toward a complete human genome sequence. (PubMed id 9847074)1 Wilson R. (1998)
  9. Function of FGF-4 in limb development. (PubMed id 7999365)9 Niswander L....Martin G. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 2128 HGNC: 3506 AceView: EVX1 Ensembl:ENSG00000106038 euGenes: HUgn2128
ECgene: EVX1 H-InvDB: EVX1

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for EVX1 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for EVX1 gene:
Search GeneIP for patents involving EVX1

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 Browse Purified and Recombinant Proteins at EMD Millipore
 EMD Millipore Mono- and Polyclonal Antibodies for the study of EVX1
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 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for EVX1  
 Browse OriGene qPCR primer pairs and template standards   OriGene Protein Over-expression Lysate for EVX1  
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 OriGene ORF clones in mouse, rat for EVX1   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for EVX1   OriGene Custom Protein Services for EVX1  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat EVX1
 QIAGEN SeqTarget long-range PCR primers for resequencing EVX1
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat EVX1
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat EVX1
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat EVX1
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 GenScript Custom Purified and Recombinant Proteins Services for EVX1 GenScript cDNA clones with any tag delivered in your preferred vector for EVX1
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 GenScript Custom overexpressing Cell Line Services for EVX1 CloneReady with Over 120,000 Genes
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 Search for Antibodies & Assays

 Regulatory tfbs in EVX1 promoter
 Search Chromatin IP Primers for EVX1
 RT2 qPCR Primer Assay in human, mouse, rat EVX1
 Search GNC Networks for EVX1
 SABiosciences Custom PCR Arrays for EVX1
 Search Tocris compounds for EVX1
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 EVX1 antibodies
 EVX1 lysates
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 See all of Abcam's Antibodies, Kits and Proteins for EVX1
 Custom Antibody / Protein Production Service
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 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Proteins for EVX1
 Antibodies for EVX1
 ELISAs for EVX1
 CLIAs for EVX1
 Search LifeMap BioReagents cell lines for EVX1
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for EVX1
 Browse SwitchGear 3'UTR luciferase reporter plasmids for EVX1
 SwitchGear Promoter luciferase reporter plasmids for EVX1
 ThermoFisher Antibodies for EVX1
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat EVX1
 inGenious Targeting Laboratory - Custom generated mouse model solutions for EVX1
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for EVX1
Customized:
 lentivirus for stable overexpression of EVX1
 lentivirus expression plasmids for stable overexpression of EVX1
 adenovirus for overexpression of EVX1
 LSBio Antibodies in human, mouse, rat for EVX1
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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transforming growth factor, beta 1
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