Aliases for ETV7 Gene
External Ids for ETV7 Gene
Previous GeneCards Identifiers for ETV7 Gene
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene (PMID:11108721).[provided by RefSeq, May 2011]
GeneCards Summary for ETV7 Gene
ETV7 (Ets Variant 7) is a Protein Coding gene. Diseases associated with ETV7 include ewing sarcoma and prostate cancer. Among its related pathways are Transcriptional misregulation in cancer and Dorso-ventral axis formation. GO annotations related to this gene include sequence-specific DNA binding transcription factor activity and sequence-specific DNA binding. An important paralog of this gene is ELF4.
UniProtKB/Swiss-Prot for ETV7 Gene
Transcriptional repressor; binds to the DNA sequence 5-CCGGAAGT-3. Isoform A does not seem to have a repressor activity. Isoform C does not seem to have a repressor activity