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ETV7 Gene

protein-coding   GIFtS: 56
GCID: GC06M036381

Ets Variant 7

(Previous name: ets variant gene 7 (TEL2 oncogene))
  See ETV7-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ets Variant 71 2     ETS-Related Protein Tel22 3
TEL22 3 5     TEL-22
TELB2 3 5     Ets Transcription Factor TEL-2b2
Ets Variant Gene 7 (TEL2 Oncogene)1 2     Transcription Factor ETV72
TEL2 Oncogene1 2     TREF3
Tel-Related Ets Factor2 3     Transcription Factor Tel-23
ETS Translocation Variant 72 3     

External Ids:    HGNC: 181601   Entrez Gene: 515132   Ensembl: ENSG000000100307   OMIM: 6052555   UniProtKB: Q9Y6033   

Export aliases for ETV7 gene to outside databases

Previous GC identifers: GC06M036323 GC06M036380 GC06M036430 GC06M036052


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ETV7 Gene:
The protein encoded by this gene belongs to the ETS family of transcription factors, which is a large group of
evolutionarily conserved transcriptional regulators that play an important role in a variety of cellular
processes throughout development and differentiation, and are involved in oncogenesis as well. This protein is
predominantly expressed in hematopoietic tissues. Several alternatively spliced transcript variants encoding
different isoforms have been described for this gene (PMID:11108721).(provided by RefSeq, May 2011)

GeneCards Summary for ETV7 Gene:
ETV7 (ets variant 7) is a protein-coding gene. Diseases associated with ETV7 include prostate cancer. GO annotations related to this gene include sequence-specific DNA binding and sequence-specific DNA binding transcription factor activity. An important paralog of this gene is ELK4.

UniProtKB/Swiss-Prot: ETV7_HUMAN, Q9Y603
Function: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a
repressor activity. Isoform C does not seem to have a repressor activity

Gene Wiki entry for ETV7 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000006.11  NC_018917.2  NT_007592.16  
Regulatory elements:
   Regulatory transcription factor binding sites in the ETV7 gene promoter:
         Bach1   RP58   STAT1   AP-1   Bach2   MyoD   FOXL1   N-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ETV7 promoter sequence
   Search Chromatin IP Primers for ETV7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ETV7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21   Ensembl cytogenetic band:  6p21.31   HGNC cytogenetic band: 6p21

ETV7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ETV7 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06M036381:  view genomic region     (about GC identifiers)

Start:
36,321,998 bp from pter      End:
36,356,164 bp from pter
Size:
34,167 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., eBioscience, and/or antibodies-online,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., eBioscience, and/or antibodies-online, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, Cloud-Clone Corp, antibodies-online, and/or others.)
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UniProtKB/Swiss-Prot: ETV7_HUMAN, Q9Y603 (See protein sequence)
Recommended Name: Transcription factor ETV7  
Size: 341 amino acids; 38998 Da
Secondary accessions: B3KVC2 B4DVB6 B4E1G4 Q5R3L3 Q5R3L4 Q9NZ65 Q9NZ66 Q9NZ68 Q9NZR8 Q9UNJ7
Q9Y5K4 Q9Y604
Alternative splicing: 8 isoforms:  Q9Y603-1   Q9Y603-2   Q9Y603-3   Q9Y603-4   Q9Y603-5   Q9Y603-6   Q9Y603-7   Q9Y603-8   

Explore the universe of human proteins at neXtProt for ETV7: NX_Q9Y603

Explore proteomics data for ETV7 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ETV7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (8 alternative transcripts): 
    NP_001193964.1  NP_001193965.1  NP_001193966.1  NP_001193967.1  NP_001193968.1  NP_001193969.1  NP_001193970.1  NP_057219.1  

    ENSEMBL proteins: 
     ENSP00000341843   ENSP00000362842   ENSP00000342260   ENSP00000362843   ENSP00000440592  

    ETV7 Human Recombinant Protein Products:

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    Novus Biologicals ETV7 Protein
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    Cloud-Clone Corp. Proteins for ETV7

     
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    antibodies-online proteins for ETV7 (3 products) 

     
    antibodies-online peptides for ETV7

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    antibodies-online kits for ETV7 (2 products) 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    4 InterPro protein domains:
     IPR000418 Ets_dom
     IPR011991 WHTH_DNA-bd_dom
     IPR003118 Pointed_dom
     IPR013761 SAM/pointed

    Graphical View of Domain Structure for InterPro Entry Q9Y603

    ProtoNet protein and cluster: Q9Y603

    1 Blocks protein domain: IPB003118 Sterile alpha motif (SAM)/Pointed domain

    UniProtKB/Swiss-Prot: ETV7_HUMAN, Q9Y603
    Similarity: Belongs to the ETS family
    Similarity: Contains 1 ETS DNA-binding domain
    Similarity: Contains 1 PNT (pointed) domain


    Find genes that share domains with ETV7           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ETV7_HUMAN, Q9Y603
    Function: Transcriptional repressor; binds to the DNA sequence 5'-CCGGAAGT-3'. Isoform A does not seem to have a
    repressor activity. Isoform C does not seem to have a repressor activity

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000981sequence-specific DNA binding RNA polymerase II transcription factor activity IBA--
    GO:0003700sequence-specific DNA binding transcription factor activity ----
    GO:0005515protein binding IPI12588862
    GO:0043565sequence-specific DNA binding IEA--
         
    Find genes that share ontologies with ETV7           About GenesLikeMe


    Phenotypes:
         3 GenomeRNAi human phenotypes for ETV7:
     G0/1 arrest  Increased G1 DNA content  Lamellipodia cells 

    Animal Models:
       genOway: Develop your customized and physiologically relevant rodent model for ETV7

    miRNA
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    miRTarBase miRNAs that target ETV7:
    hsa-mir-1 (MIRT023696)

    Block miRNA regulation of human, mouse, rat ETV7 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate ETV7:
    hsa-miR-4323
    SwitchGear 3'UTR luciferase reporter plasmidETV7 3' UTR sequence
    Inhib. RNA
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    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETV7

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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ETV7_HUMAN, Q9Y603: Nucleus
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus5
    cytosol2
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--

    Find genes that share ontologies with ETV7           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ETV7 About    
    See pathways by source

    SuperPathContained pathways About
    1Transcriptional misregulation in cancer
    Transcriptional misregulation in cancer
    2Dorso-ventral axis formation
    Dorso-ventral axis formation


    Find genes that share SuperPaths with ETV7           About GenesLikeMe

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways



    2 Kegg Pathways  (Kegg details for ETV7):
        Dorso-ventral axis formation
    Transcriptional misregulation in cancer

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ETV7
    Interactions:

        Search GeneGlobe Interaction Network for ETV7

    STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

    Selected Interacting proteins for ETV7 (Q9Y6033 ENSP000003418434) via UniProtKB, MINT, STRING, and/or I2D (see all 68)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    L3MBTL1Q9Y4683, ENSP000003622274I2D: score=2 STRING: ENSP00000362227
    IRF4Q153063, ENSP000003703434I2D: score=1 STRING: ENSP00000370343
    AFF4ENSP000002653434STRING: ENSP00000265343
    UBE2SENSP000002645524STRING: ENSP00000264552
    ELLENSP000002628094STRING: ENSP00000262809
    About this table

    Gene Ontology (GO): 5 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006355regulation of transcription, DNA-templated ----
    GO:0006357regulation of transcription from RNA polymerase II promoter IBA--
    GO:0006366transcription from RNA polymerase II promoter TAS10828014
    GO:0009887organ morphogenesis TAS10828014
    GO:0030154cell differentiation IBA--

    Find genes that share ontologies with ETV7           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ETV7

    6 Novoseek inferred chemical compound relationships for ETV7 gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    tyrosine 19.4 3 12149229 (1), 9695962 (1), 11435425 (1)
    12-o-tetradecanoylphorbol 13-acetate 11.5 1 9733767 (1)
    calcium 3.31 1 10406461 (1)
    estrogen 0 2 16344619 (1), 14603248 (1)
    retinoic acid 0 1 12485937 (1)
    rapamycin 0 1 16344619 (1)



    Find genes that share compounds with ETV7           About GenesLikeMe



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ETV7 gene (8 alternative transcripts): 
    NM_001207035.1  NM_001207036.1  NM_001207037.1  NM_001207038.1  NM_001207039.1  NM_001207040.1  NM_001207041.1  NM_016135.3  

    Unigene Cluster for ETV7:

    Ets variant 7
    Hs.272398  [show with all ESTs]
    Unigene Representative Sequence: AK122796
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000340181(uc003omb.3 uc010jwj.3 uc010jwh.3) ENST00000373737(uc010jwi.3)
    ENST00000339796(uc003olz.2 uc003oma.2) ENST00000373738(uc003omc.3 uc011dtl.2)
    ENST00000538992
    miRNA
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    1 qRT-PCR Assays for microRNA that regulate ETV7:
    hsa-miR-4323
    SwitchGear 3'UTR luciferase reporter plasmidETV7 3' UTR sequence
    Inhib. RNA
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      QuantiTect SYBR Green Assays in human, mouse, rat ETV7
      QuantiFast Probe-based Assays in human, mouse, rat ETV7

    Additional mRNA sequence: 

    AF116508.1 AF116509.1 AF116510.1 AF147782.1 AF175387.3 AF218235.1 AF218365.1 AF218366.1 
    AJ276205.1 AK026144.1 AK122796.1 AK223424.1 AK301011.1 AK303829.1 BC035853.1 

    5 DOTS entries:

    DT.92422677  DT.75129627  DT.92422678  DT.75182687  DT.100670488 

    Selected AceView cDNA sequences (see all 45):

    AF218365 AI242250 AA748867 AJ276205 AA604808 AF116509 AF116510 AF116508 
    CR622547 AF218235 AI351841 BI963015 AI394727 CB854636 AF218366 BF195445 
    NM_016135 AF147782 AK026144 AI829933 BF594296 BF000323 AI343380 BX480420 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ETV7 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5a · 5b ^ 6 ^ 7 ^ 8 ^ 9 ^ 10
    SP1:                    -                 -                                             
    SP2:                    -                                                               
    SP3:                    -                 -                 -                           
    SP4:                    -     -           -                                             
    SP5:                    -           -     -                                             


    ECgene alternative splicing isoforms for ETV7

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ETV7 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACCTTGGATT
    ETV7 Expression
    About this image

    ETV7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ETV7 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.272398

    UniProtKB/Swiss-Prot: ETV7_HUMAN, Q9Y603
    Tissue specificity: Expressed in hematopoietic tissues

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for ETV7 gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    dog
    (Canis familiaris)
    Mammalia ETV71 ets variant 7 83.73(n)
    77.54(a)
      481764  XM_005627273.1  XP_005627330.1 
    chicken
    (Gallus gallus)
    Aves ETV71 ets variant 7 62.93(n)
    62.31(a)
      419813  XM_004934881.1  XP_004934938.1 
    lizard
    (Anolis carolinensis)
    Reptilia ETV76
    ets variant 7
    44(a)
    1 ↔ 1
    4(123406900-123421692)
    zebrafish
    (Danio rerio)
    Actinopterygii etv71 ets variant 7 55.96(n)
    53.31(a)
      100009655  NM_001083024.1  NP_001076493.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Eip74EF6
    Ecdysone-induced protein 74EF
    8(a)
    many ↔ many
    3L(17551772-17612425)
    worm
    (Caenorhabditis elegans)
    Secernentea ets-46
    Protein ETS-4, isoform b (ets-4) mRNA, complete cd...
    16(a)
    1 → many
    X(6519107-6522852) WBGene00017687


    ENSEMBL Gene Tree for ETV7 (if available)
    TreeFam Gene Tree for ETV7 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ETV7 gene
    ELK42  ELF32  ELF42  ELF12  ELF52  ELK12  SPDEF2  ETV62  
    EHF2  ELF22  ELK32  
    1 SIMAP similar gene for ETV7 using alignment to 1 protein entry:     ETV7_HUMAN:
    ELF5

    Find genes that share paralogs with ETV7           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ETV7 (see all 995)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs77689391,2
    C,A,H--36064838(+) ATATGA/GAAAAA 8 -- int1 trp30--------
    rs339707631,2
    C--36069599(+) TGAAG-/TAGGCC 8 -- int10--------
    rs1488096131,2
    --36232603(+) TAATTG/TAATCA 2 -- ds50010--------
    rs1415697391,2
    --36232632(+) CTCCCA/GTGCTG 2 -- ds50010--------
    rs1508934611,2
    --36232725(+) GCCACG/TATGTA 2 -- ds50010--------
    rs1123596211,2
    C,F--36232837(+) GTCTCG/AGGTAT 2 -- ds50012Minor allele frequency- A:0.10WA 120
    rs1171189671,2
    C,F--36232866(+) AAAACG/AGACTA 2 -- ds50011Minor allele frequency- A:0.03EA 120
    rs1832301911,2
    --36232875(+) TAATAC/GAATGA 2 -- ds50010--------
    rs1867577391,2
    --36232970(+) GTTTTG/TTGTCT 2 -- ds50010--------
    rs800065311,2
    F--36232977(+) GTCTTT/CTTATT 2 -- ds50011Minor allele frequency- C:0.07NA 120

    HapMap Linkage Disequilibrium report for ETV7 (36321998 - 36356164 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 3 variations for ETV7:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv1651866CNV Insertion17803354
    nsv885806CNV Gain21882294
    esv8401CNV Gain19470904

    Site Specific Mutation Identification with PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 605255    OMIM disorders: --

    1 disease for ETV7:    
    About MalaCards
    prostate cancer


    Find genes that share disorders with ETV7           About GenesLikeMe

    Selected Novoseek inferred disease relationships for ETV7 gene (see all 21)    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    ewings sarcoma 71.8 11 18927503 (2), 11550284 (1), 12907633 (1), 12557222 (1) (see all 10)
    prostate cancer 45.5 23 20479932 (2), 18037958 (1), 16575200 (1), 18245377 (1) (see all 18)
    tumors 43.3 23 14662758 (2), 9467955 (1), 12888293 (1), 18567002 (1) (see all 22)
    erythroleukemia 38 2 17374502 (1), 12556498 (1)
    cancer 37.4 13 15298723 (2), 16307850 (1), 16213704 (1), 12898592 (1) (see all 9)
    primitive neuroectodermal tumor pnet 32.3 2 12557222 (1), 11313995 (1)
    metastasis 31.7 8 9467955 (1), 10564827 (1), 12584571 (1), 15298723 (1) (see all 8)
    leukemia 28 3 14557674 (1), 12588862 (1), 9694803 (1)
    breast cancer 26.4 6 19505923 (2), 18922924 (1), 16897429 (1), 19566835 (1) (see all 5)
    ovarian carcinoma 20.4 2 12716042 (1), 17305482 (1)

    Genetic Association Database (GAD): ETV7
    Human Genome Epidemiology (HuGE) Navigator: ETV7 (1 document)

    Export disorders for ETV7 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ETV7 gene, integrated from 10 sources (see all 234):
    (articles sorted by number of sources associating them with ETV7)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and characterization of a new human ETS-family transcription factor, TEL2, that is expressed in hematopoietic tissues and can associate with TEL1/ETV6. (PubMed id 10828014)1, 2, 3, 9 Potter M.D.... Grosveld G.C. (Blood 2000)
    2. Tel-2, a novel transcriptional repressor related to the Ets factor Tel/ETV-6. (PubMed id 11108721)1, 2, 3 Gu X....Libermann T.A. (J. Biol. Chem. 2001)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    7. Characterization of a novel ETS gene, TELB encoding a protein structurally and functionally related to TEL. (PubMed id 11032031)1, 2 Poirel H.... Bernard O.A. (Oncogene 2000)
    8. The human L(3)MBT Polycomb group protein is a transcriptional repressor and interacts physically and functionally with TEL (ETV6). (PubMed id 12588862)1, 9 Boccuni P.... Nimer S.D. (J. Biol. Chem. 2003)
    9. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)
    10. Toward an understanding of the protein interaction network of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (Mol. Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 51513 HGNC: 18160 AceView: ETV7 Ensembl:ENSG00000010030 euGenes: HUgn51513
    ECgene: ETV7 Kegg: 51513 H-InvDB: ETV7

    (According to HUGE)
    About This Section

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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for ETV7 Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for ETV7 Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for ETV7 gene:
    Search GeneIP for patents involving ETV7

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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