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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

ETV3 Gene

protein-coding GIFtS: 48
GCID: GC01M157090

ets variant 3

(Previous names: ets variant gene 3, ETS family transcriptional repressor,...)

Explore 2 diseases affiliated with
ETV3 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Ets Variant 3¹ ²		METS² ³
PE-1¹ ² ³		ETS Domain Transcriptional Repressor PE1² ³
PE1² ³ ⁵		Ets Variant Gene 3¹
Ets Variant Gene 3, ETS Family Transcriptional Repressor¹ ²		BA110J1.4¹
Mitogenic Ets Transcriptional Suppressor² ³		ETS Translocation Variant 3²

External Ids:	HGNC: 3492¹	Entrez Gene: 2117²	Ensembl: ENSG00000117036⁷	OMIM: 164873⁵	UniProtKB: P41162³

Export aliases for ETV3 gene to outside databases

Previous GC identifers: GC01M154963 GC01M152859 GC01M153872 GC01M154311 GC01M153907 GC01M155357 GC01M128452

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: ETV3_HUMAN, P41162

Function: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by

repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000001.10 NC_018912.1 NT_004487.19

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the ETV3 gene promoter:
AML1a STAT3
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: ETV3 promoter sequence

Search SABiosciences Chromatin IP Primers for ETV3

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETV3

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q21-q23 Ensembl cytogenetic band: 1q23.1 HGNC cytogenetic band: 1q21-q23

ETV3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ETV3 gene location

GeneLoc information about chromosome 1 GeneLoc Exon Structure

GeneLoc location for GC01M157090: view genomic region (about GC identifiers)

Start:	157,090,983 bp from pter	End:	157,108,383 bp from pter
Size:	17,401 bases	Orientation:	minus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: ETV3_HUMAN, P41162 (See protein sequence)

Recommended Name: ETS translocation variant 3

Size: 512 amino acids; 57001 Da

Subcellular location: Nucleus (Potential)

Sequence caution: Sequence=AAA60949.1; Type=Frameshift; Positions=174;

Secondary accessions: B4E3M7 Q8TAC8 Q9BX30

Alternative splicing: 2 isoforms: P41162-1 P41162-2

Explore the universe of human proteins at neXtProt for ETV3: NX_P41162

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P41162

ETV3 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins (2 alternative transcripts):

NP_001138784.1 NP_005231.1

ENSEMBL proteins:

ENSP00000357175 ENSP00000327316

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells OriGene Protein Over-expression Lysate: ETV3 OriGene Custom Protein Services for ETV3
	GenScript Custom Purified and Recombinant Proteins Services for ETV3
	Novus Biologicals ETV3 Proteins Novus Biologicals ETV3 Lysate
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for ETV3

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	NAS	--
GO:0017053	transcriptional repressor complex	IEA	--

ETV3 for ontologies About GeneDecksing

ETV3 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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	GenScript Custom Superior Antibodies Services for ETV3
	Novus Biologicals ETV3 Antibody
	Abcam antibodies for ETV3
	Uscn Antibodies for ETV3
	Search ThermoFisher Antibodies for ETV3

Assay Products for ETV3:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for ETV3
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for ETV3

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

ETV3 for domains About GeneDecksing

2 InterPro domains/families:

IPR000418 Ets_dom

IPR011991 WHTH_trsnscrt_rep_DNA-bd_dom

Graphical View of Domain Structure for InterPro Entry P41162

ProtoNet protein and cluster: P41162

UniProtKB/Swiss-Prot: ETV3_HUMAN, P41162

Similarity: Belongs to the ETS family

Similarity: Contains 1 ETS DNA-binding domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: ETV3_HUMAN, P41162

Function: Transcriptional repressor that contribute to growth arrest during terminal macrophage differentiation by

repressing target genes involved in Ras-dependent proliferation. Represses MMP1 promoter activity

Genatlas biochemistry entry for ETV3:

ETS variant gene 3,expressed in numerous cell lines,divergent member of the winged helix-turn-helix superfamily

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ETV3
		8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate ETV3 (see all 11):
		hsa-miR-2052 hsa-miR-3140-3p hsa-miR-187* hsa-miR-222 hsa-miR-3921 hsa-miR-221 hsa-miR-3161 hsa-miR-145

		SwitchGear 3'UTR luciferase reporter plasmid: ETV3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ETV3 (see all 7) OriGene shRNA RFP: ETV3 OriGene siRNA: ETV3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ETV3

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for ETV3

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETV3 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETV3 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): ETV3 (NM_001145312)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ETV3
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ETV3

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for ETV3
		Search LifeMap BioReagents cell lines for ETV3

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETV3

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003674	molecular_function	ND	--
GO:0003700	sequence-specific DNA binding transcription factor activity	IEA	--
GO:0005515	protein binding	--	--
GO:0043565	sequence-specific DNA binding	IEA	--

ETV3 for ontologies About GeneDecksing

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

DNA Methylation and Transcriptional Repression

Macrophage Differentiation and Growth Inhibition by METS

0.30

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ETV3

Macrophage Differentiation and Growth Inhibition by METS

Interactions:

SABiosciences Gene Network Central^TM Interacting Genes and Proteins Network for ETV3

STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

2 Interacting proteins for ETV3 (P41162³ ENSP00000357175⁴) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MYC	P01106³, ENSP00000367207⁴	I2D: score=1 STRING: ENSP00000367207
DDX20	Q9UHI6³, ENSP00000358716⁴	I2D: score=3 STRING: ENSP00000358716

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0000122	negative regulation of transcription from RNA polymerase II promoter	IEA	--
GO:0006351	transcription, DNA-dependent	IEA	--
GO:0008150	biological_process	ND	--

ETV3 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for ETV3
Search CenterWatch for drugs/clinical trials and news about ETV3

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for ETV3 gene (2 alternative transcripts):

NM_001145312.1 NM_005240.1

Unigene Cluster for ETV3:

Ets variant 3

Hs.105636 [show with all ESTs]

Unigene Representative Sequence: AK316274

3 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000368192(uc001fqr.2) ENST00000326786(uc001fqt.3) ENST00000460850

miRNA Products:		Browse 3'-UTR reporter clones for miRNA target validation Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat ETV3
		8/11 QIAGEN miScript miRNA Assays for microRNAs that regulate ETV3 (see all 11):
		hsa-miR-2052 hsa-miR-3140-3p hsa-miR-187* hsa-miR-222 hsa-miR-3921 hsa-miR-221 hsa-miR-3161 hsa-miR-145

		SwitchGear 3'UTR luciferase reporter plasmid: ETV3 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ETV3 (see all 7) OriGene shRNA RFP: ETV3 OriGene siRNA: ETV3
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ETV3

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETV3 (see all 4) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETV3 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector (see all 2): ETV3 (NM_001145312)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for ETV3
		Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ETV3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETV3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ETV3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETV3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETV3

Additional cDNA sequence:

AF218540.1 AK304789.1 AK316274.1 BC022868.1 L16464.1

4 DOTS entries:

DT.95332215 DT.404458 DT.430587 DT.95254527

24/30 AceView cDNA sequences (see all 30):

BC022868 BM695111 AI791558 AA947850 BX091144 AA948144 BM666885 AW059911

AF218540 AL601147 BU686728 AI793162 L16464 AV660485 BG942091 AA915991

AI733068 BF176184 AI733226 BF087762 NM_005240 M78749 AW893562 AW893558

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

ETV3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TTTGCAGTGA

About this image

ETV3 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

Definitive endoderm-like cells (A scalable, suspensi...)

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See ETV3 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ETV3

SOURCE GeneReport for Unigene cluster: Hs.105636

SABiosciences Custom PCR Arrays for ETV3

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETV3 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse, rat ETV3
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETV3
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETV3

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETV3

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for ETV3 gene from 5/16 species (see all 16) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	ETV3¹	ets variant 3	74.31(n) 77.87(a)		426718 XM_424336.3 XP_424336.3
lizard (Anolis carolinensis)	Reptilia	ETV3L⁶ ETV3⁶	--	80(a) 67(a)	possible ortholog possible ortholog	GL343637.1(169203-172408) GL343637.1(137383-145465)
African clawed frog (Xenopus laevis)	Amphibia	Xl.32326²	Xenopus laevis transcribed sequence with moderate similarity more	83.37(n)		BJ626027.1
zebrafish (Danio rerio)	Actinopterygii	si:ch211-265g22.4⁶	si:ch211-265g22.4	31(a)	possible ortholog	2(44427193-44432915)
worm (Caenorhabditis elegans)	Secernentea	ets-7⁶ ets-8⁶ (see all 4)	Protein ETS-8 (see all 4)	18(a) 18(a) (see all 4)	possible ortholog possible ortholog (see all 4)	V(7557738-7558764) IV(1159637-1161545)

ENSEMBL Gene Tree for ETV3 (if available)
TreeFam Gene Tree for ETV3 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for ETV3 gene

ELK4² ETV1² ERF² ETV5² ETV3L² ETS1² GABPA² ETS2²

ERG² ELK1² FEV² ETV4² ETV2² ELK3² FLI1²

3 SIMAP similar genes for ETV3 using alignment to 1 protein entry: ETV3_HUMAN:

ELF5 ERF ETV3L

ETV3 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 1 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs181320529^1,2		--	157094072(+)	`AAGAGC/TAACAT`	1	--	ds500¹		0	--	--	--	--
rs12028084^1,2	H	--	157094120(+)	`ATTATC/GTTATT`	1	--	ds500¹		4		NS EA	420
rs186740106^1,2		--	157094362(+)	`GAAAGC/TATAAG`	1	--	ds500¹		0	--	--	--	--
rs149036511^1,2		--	157094381(+)	`GGAAAC/TAGAGG`	1	--	ds500¹		0	--	--	--	--
rs113116975^1,2	F	--	157094483(+)	`AACCCG/CATCCC`	1	--	ut3¹		2		CSA	4
rs74116987^1,2	C,	--	157094502(+)	`AACATG/AAAAAT`	1	--	ut3¹		1		WA	2
rs62640944^1,2	C,F,	--	157094714(+)	`TCTCGG/AGNNNN`	2	/A	syn¹		4		NS WA NA EU	891
rs115176550^1,2		--	157094915(+)	`GTGCCT/CTTTTC`	2	/K	syn¹		1		WA	118
rs183796584^1,2		--	157095406(+)	`ACCTCC/TGCGGC`	2	R G	mis¹		0	--	--	--	--
rs2231857^1,2	C,H	--	157095455(-)	`GGGATA/G/TTACCC`	3	I M	mis¹ ese³		4		NS EA	420

HapMap Linkage Disequilibrium report for ETV3 (157090983 - 157108383 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ETV3: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ETV3

DNA2.0 Custom Variant and Variant Library Synthesis for ETV3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

ETV3 for disorders           About GeneDecksing

OMIM gene information: 164873    OMIM disorders: --

2 diseases for ETV3:    About MalaCards

conduct disorder adhd

2 diseases from the University of Copenhagen DISEASES database for ETV3:

Heart disease Hypertension

Export disorders for ETV3 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for ETV3 gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with ETV3)

Utopia: connect your pdf to the dynamic
world of online information

PE-1, a novel ETS oncogene family member, localizes to chromosome 1q21-q23. (PubMed id 8020980)^{1, 2, 3} Klemsz M.... Hoffman R. (1994)
The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)^{1, 2} Gregory S.G.... Bentley D.R. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
An induced Ets repressor complex regulates growth arrest during terminal macrophage differentiation. (PubMed id 12007404)^{1, 2} Klappacher G.W.... Glass C.K. (2002)
Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)¹ OlA!h J....OvA!di J. (2011)
Lysine acetylation targets protein complexes and co-regulates major cellular functions. (PubMed id 19608861)² Choudhary C.... Mann M. (2009)
Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)² Mayya V.... Han D.K. (2009)
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study. (PubMed id 18951430)¹ Anney R.J....Gill M. (2008)
Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)¹ Barbe L....Andersson-Svahn H. (2008)
Differential repression of c-myc and cdc2 gene expression by ERF and PE-1/METS. (PubMed id 17525531)¹ Hester K.D....Glass C.K. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 2117	HGNC: 3492	AceView: ETV3	Ensembl:ENSG00000117036	euGenes: HUgn2117
ECgene: ETV3	H-InvDB: ETV3

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for ETV3	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for ETV3	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for ETV3 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

About This Section

Patent Information for ETV3 gene:
Search GeneIP for patents involving ETV3

GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search

(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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	Browse OriGene Antibodies		OriGene shRNA RFP for ETV3
	OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ETV3		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETV3
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	QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ETV3
	QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ETV3
	QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETV3
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	GenScript Custom Purified and Recombinant Proteins Services for ETV3		GenScript cDNA clones with any tag delivered in your preferred vector for ETV3
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	Regulatory tfbs in ETV3 promoter
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETV3

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Search Vector BioLabs for ready-to-use adenovirus/AAV for human, mouse, rat ETV3

GeneCards Homepage - Last full update: 18 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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Category			VWF (GIFTS: 73) von Willebrand factor
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The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

The GeneCards Human Gene Database

Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes Disease genes ETV3 gene at Home site.

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ETV3 Gene

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ETV3 Gene

ets variant 3

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Functionfor ETV3 gene

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