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ETV1 Gene

protein-coding GIFtS: 63

GC07M013897

ets variant 1
(Previous name: ets variant gene 1 )
Symbol approved by the HUGO Gene Nomenclature Committee (HGNC) database

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc , and/or ⁷Ensembl, ⁸miRBase)
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Aliases
DKFZp781L0674 ^²
ER81 ^¹, ², ³
MGC104699 ^²
MGC120533 ^²
MGC120534 ^²

Descriptions
Protein ER81 ^³
ets variant 1 ^²
ets variant gene 1 ^¹, ²

External Ids
HGNC: 3490¹
Entrez Gene: 2115²
UniProtKB: P50549³
Ensembl: ENSG00000006468⁷

Search outside databases for aliases for ETV1 gene

Previous GC identifers: GC07M013579 GC07M013679 GC07M013708

(According to Entrez Gene, Wikipedia's Gene Wiki,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549

Function: Transcriptional activator that binds to DNA sequences containing the consensus

pentanucleotide 5'-CGGA[AT]-3'

Gene Wiki entry for ETV1

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 36),
and/or miRBase,
Genomic Views according to UCSC and Ensembl, Transcription factor binding sites according to SABiosciences)
About This Section

Genomic View:

UCSC Golden Path with GeneCards custom track

Transcription factor binding sites upstream to the ETV1 gene

Entrez Gene cytogenetic band: 7p21.3 Ensembl cytogenetic band: 7p21.2 HGNC cytogenetic band: 7p22

ETV1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)

GeneLoc gene densities for chromosome 7 GeneLoc Exon Structure

GeneLoc location for GC07M013897: (about GC identifiers)

Start:	13,897,379 bp from pter
End:	13,997,399 bp from pter
Size:	100,021 bases
Orientation:	minus strand

1 alternative location:

Chr7-,CRA_TCAG 13,981,766-14,079,660

RefSeq DNA sequence:

NC_000007.12 NT_007819.16 NT_079592.2

(According to ¹UniProtKB, and/or Ensembl, Phosphorylation sites according to ²Phosphosite, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Enzo Life Sciences, Abnova, OriGene and/or, Abcam,
Biochemical Assays by Invitrogen, Millipore, R&D Systems, Cell Signaling Technology, and/or Enzo Life Sciences, Ontologies according to Gene Ontology Consortium 01 Apr 2009 and Entrez Gene, Antibodies by Invitrogen, Millipore, Sigma-Aldrich, R&D Systems, Cell Signaling Technology, Abcam, Abnova, and/or Novus Biologicals)
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UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549 (See protein sequence)

Recommended Name: ETS translocation variant 1

Size: 477 amino acids; 55131 Da

Subcellular location: Nucleus (Probable)

Secondary accessions: A4D118 B2R768 O75849 Q4KMQ6 Q9UQ71 Q9Y636

Alternative splicing: 2 isoforms: P50549-1 P50549-2

Post-translational modifications:

Sumoylated¹

View phosphorylation sites using PhosphoSite²

REFSEQ proteins: NP_004947.2

ENSEMBL proteins:

ENSP00000385381 ENSP00000384085 ENSP00000384138 ENSP00000385686 ENSP00000385551 ENSP00000242066

ENSP00000382294 ENSP00000340853 ENSP00000382293

Human Recombinant Proteins

	Browse Drug Discovery Central at Invitrogen for human recombinant proteins
	Browse Purified and Recombinant Proteins at Millipore
	Browse Human Recombinant Proteins at Sigma-Aldrich
	Browse R&D Systems for human recombinant proteins
	Browse recombinant and purified proteins available from Enzo Life Sciences
	Recombinant Proteins from Abcam (ER81)
	Human Recombinant Proteins from Abnova (ETV1)

OriGene Purified Recombinant Human Protein: ETV1

1 Gene Ontology (GO) cellular component term (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005634	nucleus	IEA	--

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Antibodies for ETV1:

	Browse Antibodies Central at Invitrogen
	Browse Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Sigma-Aldrich Antibodies for ETV1
	Browse R&D Systems for Antibodies
	Antibodies from Abcam (ER81), each with their Abpromise^SM
	Monoclonal and Polyclonal Antibodies from Abnova (ETV1)
	Novus Biologicals Antibodies for ETV1

Assays for ETV1:

	Browse Invitrogen for biochemical assays
	Browse Kits and Assays available from Millipore
	Browse R&D Systems for biochemical assays
	Browse biochemical assays available from Enzo Life Sciences

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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Graphical View of Domain Structure for InterPro Entry P50549

ProtoNet protein and cluster: P50549

1 Blocks protein family: IPB006715 PEA3-type ETS-domain transcription factor

UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549

Similarity: Belongs to the ETS family

Similarity: Contains 1 ETS DNA-binding domain

(According to MGI Jun 06 2009, UniProtKB, IUBMB,and/or Genatlas,
shRNA from OriGene, Sigma-Aldrich, RNAi from Sigma-Aldrich,
RNAi Products, Clones, and Q-PCR Products from Invitrogen, Millipore, OriGene, and/or Abnova, siRNAs from Applied Biosystems, SYBR primers from OriGene, Cell-based Assays from Millipore, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ETV1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ETV1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004956

Applied Biosystems Silencer® siRNAs for ETV1

Sigma-Aldrich siRNA for ETV1

Sigma-Aldrich shRNA for ETV1

Explore Sigma-Aldrich super-pooled esiRNAs

Clones:		Browse Clone Ranger at Invitrogen for clones
		Browse Clones for the Expression of Recombinant Proteins Available from Millipore

OriGene GFP tagged cDNA clone in CMV expression vector: NM_004956
Myc/DDK tagged cDNA clone in CMV expression vector: NM_004956
untagged cDNA clone in CMV expression vector: NM_004956

Primers:

Browse Quantitative PCR Central at Invitrogen for Q-PCR LUX™ Primers

OriGene genome-wide validated SYBR primer pairs: NM_004956

UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549

Function: Transcriptional activator that binds to DNA sequences containing the consensus

pentanucleotide 5'-CGGA[AT]-3'

Genatlas biochemistry entry for ETV1:

ETS variant 1,transcription factor of the ETS family,divergent member of the winged

helix-turn-helix superfamily,fused with EWS in translocation t(7;22)(p22;q12)

5 MGI mutant phenotypes (inferred from 5 alleles) (MGI details for Etv1):

behavior/neurological

growth/size

life span-post-weaning/aging

muscle

nervous system

2 Gene Ontology (GO) molecular function terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0003700	transcription factor activity	TAS	7700648
GO:0043565	sequence-specific DNA binding	IEA	--

About this table

(Pathways according to Invitrogen (maps by GeneGo), Millipore, Cell Signaling Technology, Sigma-Aldrich, KEGG and/or UniProtKB,
Sets of similar genes according to GeneDecks, Proteins Network according to SABiosciences, Interactions according to ¹UniProtKB, ²MINT, and/or ³STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2009 via Entrez Gene.)
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Gene Network Central^TM Interacting Genes and Proteins Network for ETV1

5/30 Interacting proteins for ETV1 (ENSP00000242066³) via UniProtKB, MINT, and/or STRING (see all 30 )

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
MAPK14	ENSP00000229794³	STRING (score=.961)
TMPRSS2	ENSP00000330330³	STRING (score=.961)
MAPKAPK2	ENSP00000356070³	STRING (score=.96)
EWSR1	ENSP00000330516³	STRING (score=.953)
RPS6KA5	ENSP00000261991³	STRING (score=.953)

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3 Gene Ontology (GO) biological process terms (links to tree view):

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006350	transcription	IEA	--
GO:0006355	regulation of transcription, DNA-dependent	IEA	--
GO:0006366	transcription from RNA polymerase II promoter	TAS	7700648

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(Chemical Compounds according to UniProtKB, Enzo Life Sciences, Sigma-Aldrich, Tocris Bioscience, and/or Novoseek and Drugs according to Enzo Life Sciences and/or PharmGKB)
About This Section

Browse drugs & compounds from Enzo Life Sciences

Browse Small Molecules at Sigma-Aldrich

Browse Tocris compounds for ETV1
1 Novoseek chemical compound relationship for ETV1 gene

Compound	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
tyrosine	0.00	1	14747462 (1)

About this table

(GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 219 Homo sapiens; Jun 2 2009) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView,
non coding RNAs according to RNAdb,
ESTs according to GeneTide,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from Invitrogen, Millipore, and/or Abnova,
siRNAs from Applied Biosystems, Sigma-Aldrich,
shRNA from Sigma-Aldrich, OriGene,
Tagged/untagged cDNA clones from OriGene,
Expression Assays from Applied Biosystems)
About This Section

Inhib. RNA:		Invitrogen RNAi Products for gene knock-down (ETV1)
		Browse for Gene Knock-down Tools from Millipore
		Abnova Chimera RNAi Products for Gene knock-down (ETV1)

OriGene 29mer shRNA kit in GFP-retroviral vector: NM_004956

Sigma-Aldrich siRNA for ETV1

Sigma-Aldrich shRNA for ETV1

Explore Sigma-Aldrich super-pooled esiRNAs

Applied Biosystems Silencer® siRNAs:

NM_004956

REFSEQ mRNAs for ETV1 gene:

NM_004956.3

Applied Biosystems TaqMan ® Gene Expression Assays:

NM_004956

              OriGene GFP tagged cDNA clone in CMV expression vector: NM_004956
                                 Myc/DDK tagged cDNA clone in CMV expression vector: NM_004956
                                 untagged cDNA clone in CMV expression vector: NM_004956

Additional cDNA sequence:

AB209202.1 AF070641.1 AJ012492.1 AK055368.1 AK293802.1 AK294572.1 AK294755.1 AK299693.1

AK309190.1 AK311089.1 AK311134.1 AK311194.1 AK311707.1 AK312863.1 AK316007.1 BC042950.2

BC045776.1 BC098403.1 BC106762.1 BC106763.1 CR627389.1 EF632110.1 U17163.1 X87175.1

12 DOTS entries:

DT.100718526 DT.209406 DT.101979255 DT.121042940 DT.121042939 DT.121042925 DT.40129275 DT.65285559

DT.95117185 DT.100680153 DT.121042928 DT.121042952

24/127 AceView cDNA sequences (see all 127 ):

AL120951 BX282221 AF070641 AI870855 BQ894857 AI537939 BU681598 AI291719

AA593775 AI918670 NM_004956 AI801685 AI696120 AA486926 BG779436 BF222787

BE671608 BM698730 AI589102 BF110168 BF593408 AW274929 AI655920 AI637775

highest scoring ESTs for ETV1:

BC045776 U17163 X87175 AA630663 AB209202 AF070641 AI640634 AU123808 BC098403 BI546256

Unigene Cluster for ETV1:

Ets variant 1

Hs.22634 [show with all ESTs]

Unigene Representative Sequence: NM_004956

GeneLoc Exon Structure

5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ETV1 (see all 8 )

ExUns:	1	^	2	^	3a	·	3b	·	3c	^	4a	·	4b	^	5a	·	5b	^	6a	·	6b	^	7	^	8	^	9	^	10a	·	10b	^	11	^	12	^	13	^	14	^	15a	·	15b	^	16a	·	16b	^	17a	·	17b
SP1:																			-								-																				-
SP2:											-		-						-								-										-										-
SP3:																			-						-		-																				-
SP4:			-		-		-		-										-								-
SP5:																			-

About this scheme

ECgene alternative splicing isoforms for ETV1

9 Ensembl transcripts including schematic representations:

ENST00000405192 ENST00000405358 ENST00000403527 ENST00000403685 ENST00000405218 ENST00000242066

ENST00000399359 ENST00000343495 ENST00000399357

(Experimental results according to ¹GeneNote and GNF BioGPS,
probe sets-to-genes annotations according to ²GeneAnnot , ³GeneTide , Sets of similar genes according to GeneDecks, Electronic Northern calculations according to data from UniGene (Build 219 Homo sapiens), SAGE tags according to CGAP, plus additional links to SOURCE, and/or GNF BioGPS, and/or EXPOLDB, and/or UniProtKB,
Expression Assays from Applied Biosystems )
About This Section

ETV1 expression in normal and diseased human tissues

Applied Biosystems TaqMan ® Gene Expression Assays for ETV1

¹ / ² / ³

14 probe-sets matching ETV1 gene

Affymetrix probe-set	Array	# genes	Sensitivity	Specificity	Correlation	Length	Gb_Accession	Consensus	Uniqueness	Score	Rank
Affymetrix probe-set	Array	GeneAnnot data			GeneNote data		GeneTide data
59193_at²^{, 3}	U95-C	1	1.00	1.00	0.97	1.37	AI640634	0.60	1.00	0.82	1
37156_at²^{, 3}	U95-A	1	1.00	1.00	0.96	0.65	AF070641	0.60	1.00	0.82	1
37055_at²^{, 3}	U95-A	1	1.00	1.00	0.83	0.55	U17163	0.80	1.00	0.91	1
63421_at²^{, 3}	U95-C	1	1.00	1.00	0.96	1.56	AA630663	0.60	1.00	0.82	1
221911_at²^{, 3}	U133-A	1	1.00	1.00	--	--	BE881590	0.40	1.00	0.76	1
217061_s_at²	U133-A	2	1.00	0.95	--	--	--	--	--	--	--
206501_x_at²^{, 3}	U133-A	2	1.00	0.95	--	--	NM_004956	0.40	1.00	0.76	1
217053_x_at²^{, 3}	U133-A	2	1.00	0.95	--	--	X87175	0.80	1.00	0.91	1
221910_at²^{, 3}	U133-A	1	0.82	1.00	--	--	BF131965	0.40	1.00	0.76	1
221911_at²	U133Plus2	1	1.00	1.00	--	--	--	--	--	--	--
217061_s_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--
206501_x_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--
217053_x_at²	U133Plus2	2	1.00	0.95	--	--	--	--	--	--	--
221910_at²	U133Plus2	1	0.82	1.00	--	--	--	--	--	--	--

GeneDecks ETV1 for binary patterns associated with the probe-sets selected above

About GeneDecksing

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Data from

(Publications) and GNF BioGPS
About these images
About these images

CGAP SAGE TAG: CTAACGTTAT

SOURCE GeneReport for Unigene cluster: Hs.22634
Expression variation in blood from EXPOLDB for ETV1
UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549
Tissue specificity: Very highly expressed in brain, highly expressed in testis, lung and heart,
moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus,
very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood
leukocytes

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD and/or ⁵MGI Jun 06 2009, with possible further links to Flybase and/or WormBase, Gene Trees according to Ensembl)
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Orthologs for ETV1 gene from 5/11 species (see all 11 )

Organism	Gene	Locus	Description	Human Similarity	NCBI accessions
dog (Canis familiaris)	ETV1¹	--	ets variant 1	95.28(n) 98.52(a)	475246 XM_532480.2 XP_532480.2
chimpanzee (Pan troglodytes)	ETV1¹	--	ets variant 1	99.65(n) 99.37(a)	463270 XM_001148045.1 XP_001148045.1
cow (Bos taurus)	ETV1¹	--	ets variant 1	95.18(n) 98.11(a)	540846 NM_001046492.1 NP_001039957.1
rat (Rattus norvegicus)	Etv1¹	--	ets variant 1	93.73(n) 97.67(a)	362733 XM_343055.3 XP_343056.3
mouse (Mus musculus)	Etv1^{1, 5}	12 (18.50 cM)⁵	ets variant gene 1^{1, 5}	93.71(n)¹ 97.9(a)¹	14009¹ NM_007960.3¹ NP_031986.1¹ AF109633⁵ AF109634⁵ (see all 25)

About this table Species with no ortholog for ETV1

ENSEMBL Gene Tree for ETV1

(Paralogs according to ¹HomoloGene
and ²Ensembl, Pseudogenes according to ³Pseudogene.org)
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Paralogs for ETV1 gene

ETV4² ETV5²

(According to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, and UniProtKB, Linkage Disequilibrium by HapMap, Genotyping Reagents from Applied Biosystems)
About This Section

10/692 NCBI SNPs in ETV1 are shown (see all 692 )
(Click for Applied Biosystems TaqMan ® Genotyping Assay) (see all 275)

AB	SNP ID	Valid	Chr 7 pos	Sequence	Recs	AA Chg	Type	More	Recs	Pop	Total sample	More
AB	Genomic Data				Transcription Data				Allele Frequencies
				--	--	--		--	--			--
	rs41505^1,2	A,C,F,H,O	13996644(-)	`CGGGTT/CCTAGG`	1	--	ng3¹		12	MN EU EA WA NA	1152
	rs9785000^1,2	A,C,F,H	13897707(+)	`AAACTA/GTACTT`	1	--	ut3¹		8	EA NA EU WA	634
	rs4721286^1,2	A,C,F,H	13898507(+)	`AATAGA/TTGAAA`	1	--	ut3¹ ese³		13	NA EU EA WA	1150
	rs2073532^1,2	A,C,F,H	13996297(-)	`GAGAGG/CGAGGT`	1	--	ng3¹		5	EA EU WA	1890
	rs9639168^1,2	A,C,F,H	13945334(+)	`AGAGCC/TGATTT`	1	S/G	mis¹		15	EA NA EU WA	1306
	rs3823702^1,2	A,C,F,H	13901832(+)	`CCCACC/TCTCAA`	1	--	ut3¹ ese³		5	EA EU WA	1878
	rs3735344^1,2	A,C,F,H	13901213(+)	`ATGACA/GTGTCA`	1	--	ut3¹ ese³		5	EA EU WA	1896
	rs2073533^1,2	C,F,H	13996264(-)	`TAGAGG/AGGTTG`	1	--	ng3¹		5	EA EU WA	1168
	rs3735343^1,2	C,F,H	13900883(+)	`GAAAGA/TGAATA`	1	--	ut3¹		9	EA EU WA NA	2256
	rs41506^1,2	A,C,F	13996618(-)	`CAAGCA/CCTCCC`	1	--	ng3¹		4	NA PA EA	910

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HapMap Linkage Disequilibrium images for ETV1 (up to first 250kb)

(in which this Gene is Involved, According to OMIM, UniProtKB, Novoseek, PharmGKB, Genatlas, GeneTests, Blood group antigen gene mutations by BGMUT, HGMD, GAD, HuGE Navigator, BCGD, and/or TGDB.)
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OMIM: 600541

UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549

A chromosomal aberration involving ETV1 is a cause of Ewing sarcoma [MIM:133450].

Translocation t(7;22)(p22;q12) with EWS

7 Novoseek disease relationships for ETV1 gene

Disease	Score	Articles	PubMed IDs for Articles with Shared Sentences (# sentences)
ewings sarcoma	64.54	5	7700648 (1), 7493135 (1), 10597226 (1)
prostate cancer	59.60	48	17505060 (5), 16254181 (3), 18996329 (3), 17671502 (3) (see all 17)
tumors	35.80	22	18726892 (3), 18996329 (2), 7493135 (1), 11593430 (1) (see all 10)
metastasis	27.81	4	11593430 (1), 17505060 (1)
cancer	25.65	4	15094065 (1), 19066166 (1), 8597501 (1)
mammary tumor	25.33	1	12569367 (1)
breast cancer	12.11	7	18628953 (1), 18726892 (1), 14673140 (1), 8597501 (1)

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Human Genome Epidemiology Navigator: ETV1 (2 documents)

(Possibly Related Articles in Doctor's Guide)
About This Section

(in PubMed. Associations of this gene to articles via ¹Novoseek, ²HGNC, ³Entrez Gene, ⁴UniProtKB/Swiss-Prot, ⁵UniProtKB/TrEMBL, ⁶GAD, and/or ⁷PharmGKB)
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10/77 PubMed articles for ETV1 gene (see all 77 ):

Molecular characterization of the ets-related human transcription factor ER81. (PubMed id 7651741)^{1, 3, 4} Monte D....de Launoit Y. (1995)
A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. (PubMed id 7700648)^{1, 3, 4} Jeon I.-S.... Shapiro D.N. (1995)
Systematic identification and analysis of mammalian small ubiquitin- like modifier substrates. (PubMed id 15561718)^{3, 4} Gocke C.B.... Kang J. (2005)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{3, 4} Ota T....Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{3, 4} Gerhard D.S....Malek J. (2004)
Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)^{3, 4} Scherer S.W....Tsui L.C. (2003)
The DNA sequence of human chromosome 7. (PubMed id 12853948)^{3, 4} Hillier L.W.... Wilson R.K. (2003)
Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. (PubMed id 1340465)^{2, 3} Brown T.A. and McKnight S.L. (1992)
ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion. (PubMed id 17505060)^{1, 3} Cai C....Shemshedini L. (2007)
Rcl is a novel ETV1/ER81 target gene upregulated in breast tumors. (PubMed id 18726892)^{1, 3} Shin S.... Janknecht R. (2008)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, and/or H-InvDB)
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Entrez Gene: 2115	HGNC: 3490	AceView: ETV1	Ensembl:ENSG00000006468	euGenes: HUgn2115
ECgene: ETV1	H-InvDB: ETV1

(According to HUGE)
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(According to ATLAS, HORDE, IMGT, MTDB, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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Name	Description
ATLAS Chromosomes in Cancer entry for ETV1	Genetics and Cytogenetics in Oncology and Haematology

Licensable Technologies for ETV1
(Available from WIS Yeda, Salk, Tufts)

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(Reagents available from Applied Biosystems, Antibodies and assays by Cell Signaling Technology, Abcam, Novus Biologicals,
Sigma-Aldrich, R&D Systems, Millipore, Abnova, and/or Invitrogen, Clones available from OriGene,and/or Invitrogen, Drugs and/or compounds by Sigma-Aldrich,
Enzo Life Sciences, and/or Tocris Bioscience)
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Products for ETV1:

TaqMan ® Gene Expression Assays

TaqMan ® Genotyping Assays

Free SNP selection tool

Invitrogen iPath Pathways	Invitrogen BLOCK-iT™ RNAi
Invitrogen Antibodies	Invitrogen Assays
Invitrogen Clones	Invitrogen Q-PCR Products
Invitrogen Human Recombinant Kinases	Invitrogen Custom Antibody and Peptide Service
Invitrogen Proteins / Assays / Screening Services	Search Invitrogen catalog for ETV1-related products

	Millipore Custom Antibody & Bulk Services
	Millipore Preclinical / Clinical Development Services
	Millipore Immunoassay Services
	Millipore Target Screening & Profiling Services

	Predesigned and custom siRNAs for ETV1		Antibodies for ETV1
	Explore super-pooled esiRNAs		Browse proteins at Sigma-Aldrich
	Lentivirus-delivered shRNAs for ETV1		Browse small molecules at Sigma-Aldrich
	"Your Favorite Gene" Pathways		feedback

	Antibodies		Primer Pairs
	Cell Culture Products		ELISAs
	Flow Cytometry Kits		Protease Activity Assays & Reagents
	Cell Selection/Detection Kits & Reagents		ELISA/Assay Development Kits & Reagents
	Multiplex/Array Assay Kits & Reagents		ELISpot Kits & Development Modules
	Recombinant & Natural Proteins

	Recombinant Proteins (ETV1)
	Antibodies (ETV1)
	Chimera RNAi (ETV1)
	Custom Service for Mouse Mab
	Custom Service for Rabbit Pab from Full-length Protein

Search for Antibodies & Assays

	Recombinant Proteins (ER81)
	Antibodies (ER81)

	Tagged/untagged cDNA clones
	Validated SYBR primer pairs
	Purified proteins from HEK293T cells
	Western blot validated antibodies
	shRNA in GFP-retroviral vector

Search Tocris compounds for ETV1

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Antibodies for ETV1

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Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

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ETV1 Gene at Home site.
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ETV1 Gene

protein-coding GIFtS: 63

Aliases &
Descriptions
for ETV1

Summaries
for ETV1

Genomic Location
for ETV1

Proteins
for ETV1

Protein Domains/
Families
for ETV1

Gene Function
for ETV1

Pathways & Interactions
for ETV1

Drugs & Compounds
for ETV1

Transcripts
for ETV1

Expression
for ETV1

Orthologs
for ETV1

Paralogs
for ETV1

SNPs/Variants
for ETV1

Disorders & Mutations
for ETV1

Medical News
for ETV1

Publications
for ETV1

Search for ETV1

Genome Databases showing ETV1

Other Databases showing ETV1

Specialized Databases showing ETV1

Licensable Technologies
for ETV1

Services
for ETV1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

ETV1 Gene

protein-coding GIFtS: 63

Aliases & Descriptionsfor ETV1

Summariesfor ETV1

Genomic Locationfor ETV1

Proteinsfor ETV1

Protein Domains/Familiesfor ETV1

Gene Functionfor ETV1

Pathways & Interactionsfor ETV1

Drugs & Compoundsfor ETV1

Transcriptsfor ETV1

Expression for ETV1

Orthologsfor ETV1

Paralogsfor ETV1

SNPs/Variantsfor ETV1

Disorders & Mutationsfor ETV1

Medical Newsfor ETV1

Publicationsfor ETV1

Search for ETV1

Genome Databases showing ETV1

Other Databases showing ETV1

Specialized Databases showing ETV1

Licensable Technologiesfor ETV1

Servicesfor ETV1

Gene Index: 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z

Aliases &
Descriptions
for ETV1

Summaries
for ETV1

Genomic Location
for ETV1

Proteins
for ETV1

Protein Domains/
Families
for ETV1

Gene Function
for ETV1

Pathways & Interactions
for ETV1

Drugs & Compounds
for ETV1

Transcripts
for ETV1

Expression
for ETV1

Orthologs
for ETV1

Paralogs
for ETV1

SNPs/Variants
for ETV1

Disorders & Mutations
for ETV1

Medical News
for ETV1

Publications
for ETV1

Licensable Technologies
for ETV1

Services
for ETV1