ETV1 Gene
protein-coding GIFtS: 60
GCID: GC07M013897
|
|
ets variant 1(Previous name: ets variant gene 1 )
| |
Aliases for ETV1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Ets Variant 11 2 | | ER811 2 3 | | Ets Variant Gene 11 2 | | Ets-Related Protein 812 3 | | ETS Translocation Variant 12 |
Export aliases for ETV1 gene to outside databasesPrevious GC identifers: GC07M013579 GC07M013679 GC07M013708 GC07M013813 |
Summaries for ETV1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for ETV1: This gene encodes a member of the ETS (E twenty-six) family of transcription factors. The ETS proteins regulate manytarget genes that modulate biological processes like cell growth, angiogenesis, migration, proliferation anddifferentiation. All ETS proteins contain an ETS DNA-binding domain that binds to DNA sequences containing theconsensus 5'-CGGA(AT)-3'. The protein encoded by this gene contains a conserved short acidic transactivation domain(TAD) in the N-terminal region, in addition to the ETS DNA-binding domain in the C-terminal region. This gene isinvolved in chromosomal translocations, which result in multiple fusion proteins including EWS-ETV1 in Erwing sarcomaand at least 10 ETV1 partners (see PMID: 19657377, Table 1) in prostate cancer. In addition to chromosomalrearrangement, this gene is overexpressed in prostate cancer, melanoma and gastrointestinal stromal tumor. Multiplealternatively spliced transcript variants encoding different isoforms have been identified. (provided by RefSeq, Aug2011) UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549Function: Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' Gene Wiki entry for ETV1
|
Genomic Views for ETV1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007819.17 NT_079592.2
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the ETV1 gene promoter: TBP E2F-4 E2F-3a E2F-5 HTF FOXD3 E2F-2 SRY E2F E2F-1 Other transcription factors
Search SABiosciences Chromatin IP Primers for ETV1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETV1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7p21.3 Ensembl cytogenetic band: 7p21.2 HGNC cytogenetic band: 7p22ETV1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07M013897: view genomic region
(about GC identifiers)
Start:
|
13,930,853 bp from pter |
End:
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14,031,050 bp from pter |
Size:
|
100,198 bases |
Orientation:
|
minus strand |
1 alternative location:
| Chr7-,CRA_TCAG 13,981,766-14,081,945 |
|
Proteins for ETV1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549 (See
protein sequence)Recommended Name: ETS translocation variant 1 Size: 477 amino acids; 55131 Da
Subcellular location: Nucleus (Probable)
Sequence caution: Sequence=BAD92439.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;
2 PDB 3D structures from and Proteopedia for ETV1:4AVP (3D)
  4B06 (3D)
 
Secondary accessions: A4D118 B2R768 B7Z2I4 B7Z618 B7Z9P2 C9JT37 E9PHB1 F5GXR2 O75849 Q4KMQ6 Q59GA7Q6AI30 Q9UQ71 Q9Y636Alternative splicing: 6 isoforms: P50549-1 P50549-2 P50549-3 P50549-4 P50549-5 P50549-6 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ETV1: NX_P50549
Post-translational modifications:
Sumoylated1
Phosphorylated at Ser-191 and Ser-216 by RPS6KA1 and RPS6KA5; phosphorylation activates transcriptional activity1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P50549 ETV1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (7 alternative transcripts):
NP_001156619.1 NP_001156620.1 NP_001156621.1 NP_001156622.1 NP_001156623.1 NP_001156624.1 NP_004947.2 ENSEMBL proteins: ENSP00000405327 ENSP00000385381 ENSP00000384085 ENSP00000384138 ENSP00000385551 ENSP00000413836 ENSP00000385686 ENSP00000393078 ENSP00000394710 ENSP00000391043 ENSP00000410819 ENSP00000406931 ENSP00000242066 ENSP00000340853 ENSP00000411626 ENSP00000382293 Human Recombinant Protein Products:
Gene Ontology (GO): 1 cellular component term (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005634 | nucleus |
IEA | -- |
ETV1 for ontologies About GeneDecksing
ETV1 Antibody Products: Assay Products for ETV1: |
Protein
Domains / Families for ETV1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ETV1 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P50549ProtoNet protein and cluster: P50549 1 Blocks protein family: IPB006715 PEA3-type ETS-domain transcription factor
UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549Similarity: Belongs to the ETS familySimilarity: Contains 1 ETS DNA-binding domain |
Function for ETV1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549Function: Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3' Genatlas biochemistry entry for ETV1:ETS variant 1,transcription factor of the ETS family,divergent member of the winged helix-turn-helix superfamily,fusedwith EWS in translocation t(7;22)(p22;q12)
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETV1 (see all 10) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETV1 (see all 7) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 7): ETV1 (NM_004956) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ETV1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETV1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETV1 |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0003700 | sequence-specific DNA binding transcription factor activity |
IEA | -- | | GO:0005515 | protein binding |
IPI | -- | | GO:0043565 | sequence-specific DNA binding |
IEA | -- |
ETV1 for ontologies About GeneDecksing
Animal Models: Mouse knock-outs for ETV1: Etv1tm1.1Wds Etv1tm1Tmj 6 MGI mutant phenotypes (inferred from 6 alleles ) (MGI details for Etv1):
ETV1 for phenotypes About GeneDecksing
|
Pathways & Interactions for ETV1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Development_TGF-beta receptor signaling | | | 2 | p38 signaling mediated by MAPKAP kinases | | | 3 | Akt Signaling | |
Pathway sources See GeneCards unified pathways Show all pathways
1 EMD Millipore Pathway for ETV1 1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for ETV1 1 GeneGo (Thomson Reuters) Pathway for ETV1 1 BioSystems Pathway for ETV1 
ETV1 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for ETV1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 16)
 5/18 Interacting proteins for ETV1 (P505491, 3 ENSP000003840854) via UniProtKB, MINT, STRING, and/or I2D (see all 18)About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table
ETV1 for ontologies About GeneDecksing
|
Drugs & Compounds for ETV1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ETV1 for compounds About GeneDecksing
Browse Tocris compounds for ETV1 3 Novoseek chemical compound relationships for ETV1 gene About this table
Search CenterWatch for drugs/clinical trials and news about ETV1 
|
Transcripts for ETV1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for ETV1 gene (7 alternative transcripts): NM_001163147.1 NM_001163148.1 NM_001163149.1 NM_001163150.1 NM_001163151.1 NM_001163152.1 NM_004956.4 Unigene Cluster for ETV1: Ets variant 1 Hs.22634 [show with all ESTs]Unigene Representative Sequence: NM_00495618/24 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 24): ENST00000430479(uc021zzz.1 uc022aaa.1 uc003ssx.3 uc022aac.1) ENST00000405192 ENST00000405358 ENST00000403527 ENST00000405218 ENST00000443137 ENST00000403685 ENST00000493831 ENST00000472931(uc010ktv.3) ENST00000438956 ENST00000476720 ENST00000443608 ENST00000497115 ENST00000476355 ENST00000421381 ENST00000431887 ENST00000460438 ENST00000483075
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETV1 (see all 10) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETV1 (see all 7) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 7): ETV1 (NM_004956) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ETV1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETV1  |
Additional cDNA sequence: AB209202.1 AF070641.1 AJ012492.1 AK055368.1 AK293802.1 AK294572.1 AK294755.1 AK299693.1 AK309190.1 AK311089.1 AK311134.1 AK311194.1 AK311707.1 AK312863.1 AK316007.1 BC042950.2 BC045776.1 BC098403.1 BC106762.1 BC106763.1 CR627389.1 EF632110.1 U17163.1 X87175.1 12 DOTS entries: DT.100718526 DT.209406 DT.101979255 DT.121042940 DT.121042939 DT.121042925 DT.40129275 DT.65285559 DT.95117185 DT.100680153 DT.121042928 DT.121042952 24/127 AceView cDNA sequences (see all 127): BX096086 AW274929 BF110168 AI918670 BE671608 BF222787 AA486926 AI589102 AI637775 BU624617 AI291719 AA593775 NM_004956 AI801685 BG779436 BQ894857 BX282221 AI655920 AL120951 AF070641 BU681598 AI537939 BF593408 BM698730 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ETV1 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16a | · | 16b | ^ | 17a | · | 17b | |
| SP1: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |
| SP4: | |   | - |   | - |   | - |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for ETV1
|
Expression for ETV1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ETV1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: CTAACGTTAT
About this image See ETV1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for ETV1
SOURCE GeneReport for Unigene cluster: Hs.22634 UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549Tissue specificity: Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen,small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney andovary and not in placenta and peripheral blood leukocytes SABiosciences Expression via Pathway-Focused PCR Array including ETV1:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETV1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ETV1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETV1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETV1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETV1 |
Orthologs for ETV1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for ETV1 gene from 6/20 species (see all 20) About this table
ENSEMBL Gene Tree for ETV1 (if available) TreeFam Gene Tree for ETV1 (if available)  |
Paralogs for ETV1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for ETV1 gene
- ELK42 ETV32 ERF2 ETV52 ETV3L2 ETS12 GABPA2 ETS22
- ERG2 FEV2 ELK12 ETV42 ETV22 FLI12 ELK32
10 SIMAP similar genes for ETV1 using alignment to 8 protein entries: ETV1_HUMAN (see all proteins):ELK3 ETV5 TLS-ERG ETV2 ELF2 DDX5-ETV4 fusion FEV ETV4 FLI1 ELF5
ETV1 for paralogs About GeneDecksing
|
Genomic Variants for ETV1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 7 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for ETV1 (13930853 - 14031050 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 3 variations for ETV1 3 CNVs: 81872 0292 94385  | SABiosciences Cancer Mutation PCR Assays |
 | 1 SABiosciences qBiomarker Copy Number PCR Array containing ETV1: |
|
Disorders
/ Diseases for ETV1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ETV1 for disorders About GeneDecksing
OMIM gene information: 600541
OMIM disorders: --
UniProtKB/Swiss-Prot: ETV1_HUMAN, P50549
Defects in ETV1 are a cause of Ewing sarcoma (ES) [MIM:612219]. A highly malignant, metastatic, primitivesmall round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcomafamily of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. Theyare considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiatedform of the tumors. Note=A chromosomal aberration involving ETV1 is found in patients with Erwing sarcoma.Translocation t(7;22)(p22;q12) with EWSR1 18 diseases for ETV1: About MalaCardsgastrointestinal stromal tumor prostate cancer desmoplastic small round cell tumor prostatitis primitive neuroectodermal tumor sarcoma peripheral primitive neuroectodermal tumor melanoma neuroectodermal tumors myelodysplastic syndrome breast cancer prostate adenocarcinoma gastric cancer prostate carcinoma colorectal cancer adenocarcinoma carcinoma neuronitis 3 diseases from the University of Copenhagen DISEASES database for ETV1:Prostate cancer Peripheral primitive neuroectodermal tumor Sarcoma 7 Novoseek disease relationships for ETV1 gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ewings sarcoma |
63 |
5 |
7700648 (1), 7493135 (1), 10597226 (1) |
| prostate cancer |
58.8 |
49 |
17505060 (5), 16254181 (3), 18996329 (3), 17671502 (3) (see all 18) |
| tumors |
36.7 |
30 |
19789348 (3), 18726892 (3), 18996329 (2), 7493135 (1) (see all 13) |
| mammary tumor |
35.6 |
1 |
12569367 (1) |
| metastasis |
25.5 |
4 |
11593430 (1), 17505060 (1) |
| cancer |
24.9 |
5 |
19789348 (1), 15094065 (1), 19066166 (1), 8597501 (1) |
| breast cancer |
14.8 |
7 |
18628953 (1), 18726892 (1), 14673140 (1), 8597501 (1) |
Human Genome Epidemiology (HuGE) Navigator: ETV1 (3 documents) Export disorders for ETV1 gene to outside databases
|
Publications for ETV1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ETV1 gene, integrated from 9 sources (see all 99): (articles sorted by number of sources associating them with ETV1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Molecular characterization of the ets-related human transcription factor ER81. (PubMed id 7651741)1, 2, 9 Monte D....de Launoit Y. (1995)
- Regulation of the ETS transcription factor ER81 by the 90-kDa ribosomal S6 kinase 1 and protein kinase A. (PubMed id 12213813)1, 2, 9 Wu J. and Janknecht R. (2002)
- Regulation of the ER81 transcription factor and its coactivators by mitogen- and stress-activated protein kinase 1 (MSK1). (PubMed id 12569367)1, 2, 9 Janknecht R. (2003)
- A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1. (PubMed id 7700648)1, 2, 9 Jeon I.-S.... Shapiro D.N. (1995)
- Systematic identification and analysis of mammalian small ubiquitin- like modifier substrates. (PubMed id 15561718)1, 2 Gocke C.B.... Kang J. (2005)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins. (PubMed id 1340465)1, 3 Brown T.A. and McKnight S.L. (1992)
|
External Searches for ETV1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing ETV1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing ETV1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing ETV1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
|
About This Section
| Patent Information for ETV1 gene: Search GeneIP for patents involving ETV1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products for ETV1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
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| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for ETV1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ETV1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETV1 | | OriGene Protein Over-expression Lysate for ETV1 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for ETV1 | | OriGene 3'-UTR Clone for ETV1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETV1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETV1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | OriGene Purified Protein for ETV1 | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for ETV1 | | OriGene Custom Protein Services for ETV1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ETV1 | | Search QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ETV1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETV1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ETV1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETV1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETV1 |
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| | | Search Tocris compounds for ETV1 |
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 | | ETV1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETV1 |
|  |  |  | | | ThermoFisher Antibodies for ETV1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETV1 |
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