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ETNK1 Gene

protein-coding   GIFtS: 55
GCID: GC12P022778

Ethanolamine Kinase 1

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ethanolamine Kinase 11 2     Nbla103962
EKI12 3 5     Putative Protein Product Of Nbla103962
EKI 12 3     EC 2.7.1.823
EKI2     

External Ids:    HGNC: 246491   Entrez Gene: 555002   Ensembl: ENSG000001391637   OMIM: 6098585   UniProtKB: Q9HBU63   

Export aliases for ETNK1 gene to outside databases

Previous GC identifers: GC12P022670 GC12P022544


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for ETNK1 Gene:
This gene encodes an ethanolamine kinase, which functions in the first committed step of the
phosphatidylethanolamine synthesis pathway. This cytosolic enzyme is specific for ethanolamine and exhibits
negligible kinase activity on choline. Alternative splicing results in multiple transcript variants encoding
distinct isoforms. (provided by RefSeq, Jul 2008)

GeneCards Summary for ETNK1 Gene:
ETNK1 (ethanolamine kinase 1) is a protein-coding gene. Diseases associated with ETNK1 include scabies, and seminoma. GO annotations related to this gene include ethanolamine kinase activity. An important paralog of this gene is CHKA.

UniProtKB/Swiss-Prot: EKI1_HUMAN, Q9HBU6
Function: Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in
phosphatidylethanolamine biosynthesis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NT_009714.18  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the ETNK1 gene promoter:
         Spz1   LHX3b/Lhx3b   AP-1   Sp1   HTF   E47   GATA-6   LHX3a/Lhx3a   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidETNK1 promoter sequence
   Search Chromatin IP Primers for ETNK1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ETNK1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p12.1   Ensembl cytogenetic band:  12p12.1   HGNC cytogenetic band: 12p12.2

ETNK1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ETNK1 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P022778:  view genomic region     (about GC identifiers)

Start:
22,778,009 bp from pter      End:
22,843,608 bp from pter
Size:
65,600 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: EKI1_HUMAN, Q9HBU6 (See protein sequence)
Recommended Name: Ethanolamine kinase 1  
Size: 452 amino acids; 50968 Da
Secondary accessions: G5E969
Alternative splicing: 2 isoforms:  Q9HBU6-1   Q9HBU6-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for ETNK1: NX_Q9HBU6

Explore proteomics data for ETNK1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys172, Lys184
  • Modification sites at PhosphoSitePlus

  • See ETNK1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001034570.1  NP_061108.2  

    ENSEMBL proteins: 
     ENSP00000266517   ENSP00000334041   ENSP00000446292   ENSP00000439614  
    Reactome Protein details: Q9HBU6

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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR011009 Kinase-like_dom

    Graphical View of Domain Structure for InterPro Entry Q9HBU6

    ProtoNet protein and cluster: Q9HBU6

    1 Blocks protein domain: IPB002573 Choline/ethanolamine kinase

    UniProtKB/Swiss-Prot: EKI1_HUMAN, Q9HBU6
    Similarity: Belongs to the choline/ethanolamine kinase family


    ETNK1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: EKI1_HUMAN, Q9HBU6
    Function: Highly specific for ethanolamine phosphorylation. May be a rate-controlling step in
    phosphatidylethanolamine biosynthesis
    Catalytic activity: ATP + ethanolamine = ADP + O-phosphoethanolamine

         Enzyme Number (IUBMB): EC 2.7.1.821

         Gene Ontology (GO): 3 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0004305ethanolamine kinase activity IDA11044454
    GO:0005524ATP binding IEA--
    GO:0016772transferase activity, transferring phosphorus-containing groups ----
         
    ETNK1 for ontologies           About GeneDecksing


    Phenotypes:
         2 GenomeRNAi human phenotypes for ETNK1:
     Decreased mitotic index  Increased G1 DNA content 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ETNK1
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    miRNA
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    miRTarBase miRNAs that target ETNK1:
    hsa-mir-15b-5p (MIRT046537), hsa-mir-378a-5p (MIRT043971), hsa-mir-21-5p (MIRT030884), hsa-mir-1 (MIRT023834)

    Block miRNA regulation of human, mouse, rat ETNK1 using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ETNK1 (see all 138):
    hsa-miR-579 hsa-miR-100* hsa-miR-199a-3p hsa-miR-519a hsa-miR-130b hsa-miR-877 hsa-miR-130a* hsa-miR-23c
    Browse SwitchGear 3'UTR luciferase reporter plasmids
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    EKI1_HUMAN, Q9HBU6: Cytoplasm
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol4
    plasma membrane3
    endoplasmic reticulum1
    mitochondrion1
    peroxisome1

    Gene Ontology (GO): 2 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm ----
    GO:0005829cytosol TAS--

    ETNK1 for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for ETNK1 About    
    See pathways by source

    SuperPathContained pathways About
    1Glycerophospholipid biosynthesis
    Glycerophospholipid biosynthesis0.64
    Glycerophospholipid metabolism0.62
    Phospholipid metabolism0.64
    Synthesis of PE0.00
    2Metabolism
    Metabolism0.38
    Metabolism of lipids and lipoproteins0.37
    Metabolic pathways0.38
    3phosphatidylethanolamine biosynthesis II
    phosphatidylethanolamine biosynthesis II

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways


    1 BioSystems Pathway for ETNK1
        phosphatidylethanolamine biosynthesis II

    1 Reactome Pathway for ETNK1
        Synthesis of PE


    2 Kegg Pathways  (Kegg details for ETNK1):
        Glycerophospholipid metabolism
    Metabolic pathways

    UniProtKB/Swiss-Prot: EKI1_HUMAN, Q9HBU6
    Pathway: Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from
    ethanolamine: step 1/3


    ETNK1 for pathways           About GeneDecksing

        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ETNK1
    Interactions:

        Search GeneGlobe Interaction Network for ETNK1

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    Selected Interacting proteins for ETNK1 (Q9HBU63 ENSP000002665174) via UniProtKB, MINT, STRING, and/or I2D (see all 18)

    InteractantInteraction Details
    GeneCardExternal ID(s)
    RPS3P233963I2D: score=3 
    PCYT2ENSP000003317194STRING: ENSP00000331719
    PHOSPHO1ENSP000004069094STRING: ENSP00000406909
    UBCENSP000003448184STRING: ENSP00000344818
    NAP1L1ENSP000002611824STRING: ENSP00000261182
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006644phospholipid metabolic process TAS--
    GO:0006646phosphatidylethanolamine biosynthetic process TAS--
    GO:0044281small molecule metabolic process TAS--
    GO:0046474glycerophospholipid biosynthetic process TAS--

    ETNK1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
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      Browse compounds at ApexBio 

    Browse Tocris compounds for ETNK1 (EKI1)

    4 HMDB Compounds for ETNK1    About this table
    CompoundSynonyms CAS #PubMed Ids
    ADPadenosindiphosphorsaeure (see all 8)58-64-0--
    Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
    Ethanolamine1-Amino-2-hydroxyethane (see all 28)141-43-5--
    O-PhosphoethanolaminePhosphoryethanolamine (see all 28)1071-23-4--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for ETNK1 gene (2 alternative transcripts): 
    NM_001039481.1  NM_018638.4  

    Unigene Cluster for ETNK1:

    Ethanolamine kinase 1
    Hs.29464  [show with all ESTs]
    Unigene Representative Sequence: NM_018638
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000266517(uc001rft.3 uc009ziz.3) ENST00000335148(uc001rfs.3)
    ENST00000538218 ENST00000545979 ENST00000539974 ENST00000544191
    miRNA
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    Selected qRT-PCR Assays for microRNAs that regulate ETNK1 (see all 138):
    hsa-miR-579 hsa-miR-100* hsa-miR-199a-3p hsa-miR-519a hsa-miR-130b hsa-miR-877 hsa-miR-130a* hsa-miR-23c
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    Additional mRNA sequence: 

    AB074182.1 AF207600.2 AK027113.1 AK074425.1 AL110180.1 AL117563.1 AL137750.1 BC006111.1 
    BC037324.2 BC045794.1 BC066907.1 BT007084.1 CR749601.1 

    15 DOTS entries:

    DT.315767  DT.445990  DT.97774891  DT.408000  DT.95234982  DT.121123479  DT.121123507  DT.91747234 
    DT.95254695  DT.86856193  DT.100788998  DT.121123472  DT.121204400  DT.91720290  DT.91730982 

    Selected AceView cDNA sequences (see all 96):

    AK074425 NM_018638 AA558957 AA724933 AL137750 AW183403 CA406305 AI361619 
    BQ086206 AI140596 BC006111 BM129637 BQ102310 CK822914 AI357819 BQ045414 
    CK822915 AI003792 BP336773 AA770489 BT007084 CA412716 BI770061 BM129168 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ETNK1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAACTGGTTA
    ETNK1 Expression
    About this image

    ETNK1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ETNK1 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.29464

    UniProtKB/Swiss-Prot: EKI1_HUMAN, Q9HBU6
    Tissue specificity: Expressed in kidney, liver, placenta, heart, leukocyte, ovary and testis

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals and fungi.

    Orthologs for ETNK1 gene from Selected species (see all 16)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Etnk11 , 5 ethanolamine kinase 11, 5 88(n)1
    93.91(a)1
      6 (75.41 cM)5
    753201  NM_029250.21  NP_083526.21 
     1431672305 
    chicken
    (Gallus gallus)
    Aves ETNK11 ethanolamine kinase 1 80.24(n)
    86.43(a)
      418196  XM_416426.4  XP_416426.3 
    lizard
    (Anolis carolinensis)
    Reptilia ETNK16
    ethanolamine kinase 1
    72(a)
    1 ↔ 1
    5(6864536-6894414)
    zebrafish
    (Danio rerio)
    Actinopterygii wufb38f122 Transcribed sequence with moderate similarity to protein more 76.79(n)    57097249 
    fruit fly
    (Drosophila melanogaster)
    Insecta eas1 easily shocked 54.48(n)
    48.34(a)
      32585  NM_078640.3  NP_523364.2 
    worm
    (Caenorhabditis elegans)
    Secernentea ckc-11 ckc-1 48.17(n)
    36.77(a)
      188971  NM_001029758.2  NP_001024929.1 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes EKI16
    CKI16
    Ethanolamine kinase, primarily responsible for pho...
    Choline kinase, catalyzing the first step in phosp...
    17(a)
    15(a)
    many ↔ many
    many ↔ many
    IV(751631-753235) YDR147W
    XII(408445-410193) YLR133W


    ENSEMBL Gene Tree for ETNK1 (if available)
    TreeFam Gene Tree for ETNK1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ETNK1 gene
    CHKA2  CHKB2  CHKB-CPT1B2  ETNK22  
    2 SIMAP similar genes for ETNK1 using alignment to 3 protein entries:     EKI1_HUMAN (see all proteins):
    DKFZp434E1212    ETNK2

    ETNK1 for paralogs           About GeneDecksing


    1 Pseudogenes.org Pseudogene for ETNK1
    PGOHUM00000245717


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ETNK1 (see all 1234)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs730804621,2
    C,F--22776078(+) GTTCTG/CGGACT 2 -- us2k12Minor allele frequency- C:0.03NA EA 240
    rs1833696181,2
    --22776192(+) TCCTCC/GTCTCC 2 -- us2k10--------
    rs1880183801,2
    --22776209(+) ACAGCA/GCTTTT 2 -- us2k10--------
    rs1465669511,2
    --22776244(+) ATTTCA/CATGTC 2 -- us2k10--------
    rs38091961,2
    C,F--22776300(-) ATAATG/ACAATT 2 -- us2k12Minor allele frequency- A:0.03NA EA 240
    rs1392101401,2
    --22776365(+) TATGAA/CTATGG 2 -- us2k10--------
    rs1897500201,2
    --22776440(+) CCTAAC/TAGTTT 2 -- us2k10--------
    rs1420106041,2
    C--22776442(+) AATAG-/TTTTTT 2 -- us2k10--------
    rs1823636841,2
    --22776478(+) GACTCG/TTATTT 2 -- us2k10--------
    rs38091951,2
    C,F,H--22776605(-) TCTCTT/AGTATT 2 -- us2k1 tfbs39Minor allele frequency- A:0.16NS EA WA CSA NA 774

    HapMap Linkage Disequilibrium report for ETNK1 (22778009 - 22843608 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for ETNK1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ETNK1
    DNA2.0 Custom Variant and Variant Library Synthesis for ETNK1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 609858    OMIM disorders: --

    3 diseases for ETNK1:    
    About MalaCards
    scabies    seminoma    malaria


    ETNK1 for disorders           About GeneDecksing

    Genetic Association Database (GAD): ETNK1
    Human Genome Epidemiology (HuGE) Navigator: ETNK1 (4 documents)

    Export disorders for ETNK1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ETNK1 gene, integrated from 10 sources (see all 17):
    (articles sorted by number of sources associating them with ETNK1)
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    1. Overexpression of a mammalian ethanolamine-specific kinase accelerates the CDP-ethanolamine pathway. (PubMed id 11044454)1, 2, 3, 9 Lykidis A.... Jackowski S. (J. Biol. Chem. 2001)
    2. Coamplification of DAD-R, SOX5, and EKI1 in human testicular seminomas, with specific overexpression of DAD-R, correlates with reduced levels of apoptosis and earlier clinical manifestation. (PubMed id 11912161)1, 3, 9 Zafarana G....Looijenga L.H. (Cancer Res. 2002)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    6. Proteome-wide identification of ubiquitylation sites by conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (J. Proteome Res. 2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    10. A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (amp 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 55500 HGNC: 24649 AceView: ETNK1 Ensembl:ENSG00000139163 euGenes: HUgn55500
    ECgene: ETNK1 Kegg: 55500 H-InvDB: ETNK1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ETNK1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ETNK1 gene:
    Search GeneIP for patents involving ETNK1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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