ETFDH Gene
protein-coding GIFtS: 62
GCID: GC04P159593
|
|
electron-transferring-flavoprotein dehydrogenase
| |
Aliases
for ETFDH gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Electron-Transferring-Flavoprotein Dehydrogenase1 2 3 | | EC 1.5.5.13 8 | | ETFQO1 2 | | MADD2 5 | | ETF-QO2 3 | | Electron Transfer Flavoprotein Ubiquinone Oxidoreductase2 | | ETF Dehydrogenase2 3 | | Electron Transfer Flavoprotein-Ubiquinone Oxidoreductase, Mitochondrial2 | | ETF-Ubiquinone Oxidoreductase2 3 | | |
Export aliases for ETFDH gene to outside databasesPrevious GC identifers: GC04P160443 GC04P160022 GC04P160171 GC04P160145 GC04P159951 GC04P159812 GC04P155343 |
Summaries
for ETFDH gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ETFDH:
Electron-transferring-flavoprotein dehydrogenase in the inner mitochondrial membrane accepts electrons fromelectron-transfer flavoprotein which is located in the mitochondrial matrix and reduces ubiquinone in themitochondrial membrane. The protein is synthesized as a 67-kDa precursor which is targeted to mitochondria andprocessed in a single step to a 64-kDa mature form located in the mitochondrial membrane. Deficiency inelectron-transferring-flavoprotein dehydrogenase have been demonstrated in some patients with type IIglutaricacidemia. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ETFD_HUMAN, Q16134Function: Accepts electrons from ETF and reduces ubiquinone
Gene Wiki entry for ETFDH
|
Genomic Views
for ETFDH gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ETFDH gene promoter:
Nkx3-1 Nkx3-1 v4 SREBP-1c Nkx3-1 v1 Gfi-1 GATA-2 SREBP-1b Nkx3-1 v2 SREBP-1a Nkx3-1 v3
Other transcription factors
Search SABiosciences Chromatin IP Primers for ETFDH
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETFDH |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q32-q35 Ensembl cytogenetic band: 4q32.1 HGNC cytogenetic band: 4q32-q35ETFDH Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P159593: view genomic region
(about GC identifiers)
Start:
|
159,593,277 bp from pter |
End:
|
159,630,775 bp from pter |
Size:
|
37,499 bases |
Orientation:
|
plus strand |
|
Proteins
for ETFDH gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ETFD_HUMAN, Q16134 (See
protein sequence)Recommended Name: Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial precursor Size: 617 amino acids; 68495 Da
Cofactor: Binds 1 4Fe-4S cluster
Cofactor: FAD
Subunit: Monomer
Subcellular location: Mitochondrion inner membrane
Sequence caution: Sequence=CAD98030.1; Type=Miscellaneous discrepancy; Note=Aberrant splicing;
Secondary accessions: Q7Z347Explore the universe of human proteins at neXtProt for ETFDH: NX_Q16134
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q16134
4/21 DME Specific Peptides for ETFDH (Q16134) (see all 21)
ETFDH Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_004444.2
ENSEMBL proteins: ENSP00000425661 ENSP00000426638 ENSP00000422735 ENSP00000303552 Reactome Protein details: Q16134
Human Recombinant Protein Products:
Gene Ontology (GO): 5 cellular component terms (GO ID links to tree view): About this table
ETFDH for ontologies About GeneDecksing
ETFDH Antibody Products:
Assay Products for ETFDH: |
Protein
Domains /
Families
for ETFDH gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ETFDH for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q16134ProtoNet protein and cluster: Q16134 1 Blocks protein family: IPB007859 Electron transfer flavoprotein-ubiquinone oxidoreductase
UniProtKB/Swiss-Prot: ETFD_HUMAN, Q16134Similarity: Belongs to the ETF-QO/FixC familySimilarity: Contains 1 4Fe-4S ferredoxin-type domain |
Function
for ETFDH gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ETFD_HUMAN, Q16134Function: Accepts electrons from ETF and reduces ubiquinoneCatalytic activity: Reduced electron-transferring flavoprotein + ubiquinone = electron-transferring flavoprotein +ubiquinol Genatlas biochemistry entry for ETFDH:electron transfer flavoprotein-ubiquinone reductase,inner mitochondrial membrane,oxidative phosphorylation (OXPHOS)
Enzyme Number (IUBMB): EC 1.5.5.11 2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETFDH (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETFDH
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: ETFDH (NM_004453) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ETFDH | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETFDH |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETFDH |
Gene Ontology (GO): 5/10 molecular function terms (GO ID links to tree view) (see all 10): About this table
ETFDH for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for ETFDH:
|
Pathways & Interactions
for ETFDH gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4 
Reactome Pathways for ETFDH
ETFDH for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ETFDH
STRING Interaction
Network Preview (showing 5 interactants - click image to see 15)
5/24 Interacting proteins for ETFDH (Q161343 ENSP000003035524) via UniProtKB, MINT, STRING, and/or I2D (see all 24)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
ETFDH for ontologies About GeneDecksing
|
Drugs & Compounds
for ETFDH gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ETFDH for compounds About GeneDecksing
 Browse Tocris compounds for ETFDH
6 HMDB Compounds for ETFDH About this table
1 DrugBank Compound for ETFDH About this table
10/15 Novoseek chemical compound relationships for ETFDH gene (see all 15) About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| acyl-coa |
88.4 |
23 |
19249206 (2), 19265687 (2), 19774399 (1), 17050691 (1) (see all 16) |
| flavin semiquinone |
86.3 |
1 |
17050691 (1) |
| ubiquinone |
83.1 |
34 |
14640977 (5), 17050691 (4), 1332770 (2), 7757062 (2) (see all 14) |
| flavin |
75.4 |
5 |
17050691 (1), 17689999 (1), 10423253 (1), 20505899 (1) |
| riboflavin |
74 |
8 |
19265687 (3), 19249206 (2), 17689999 (1) |
| semiquinone |
70.7 |
4 |
9100014 (1), 10423253 (1), 9334218 (1) |
| sarcosine |
68.8 |
1 |
7798224 (1) |
| iron-sulfur |
62.4 |
6 |
16248429 (2), 1332770 (1), 8306995 (1), 17050691 (1) |
| coq10 |
61.6 |
3 |
17412732 (1), 19249206 (1) |
| hydroquinone |
38.1 |
1 |
10423253 (1) |
Search CenterWatch for drugs/clinical trials and news about ETFDH / ETFD
|
Transcripts
for ETFDH gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ETFDH gene: NM_004453.2 Unigene Cluster for ETFDH: Electron-transferring-flavoprotein dehydrogenase Hs.155729 [show with all ESTs]Unigene Representative Sequence: NM_0044538 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000512251 ENST00000511912(uc003iqb.3 uc011cjg.2 uc010iqr.3 uc011cjh.2 uc010iqs.3)
ENST00000507475 ENST00000510353(uc010iqq.3) ENST00000436096 ENST00000307738
ENST00000506422 ENST00000514148
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETFDH (see all 3)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETFDH
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: ETFDH (NM_004453) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ETFDH | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETFDH |
Additional cDNA sequence: AK293737.1 AK304838.1 AK311435.1 AK314803.1 BC011890.1 BX538129.1 EU093082.1 EU093083.1 S69232.1 12 DOTS entries: DT.209671 DT.95207471 DT.100677304 DT.101963869 DT.95365454 DT.91746328 DT.101978508 DT.100696021 DT.121229977 DT.92021646 DT.92427401 DT.75186914 24/96 AceView cDNA sequences (see all 96): BU192297 AL551954 BU663211 CR594853 CR595253 CA389559 BM905640 CR597977 BX957055 BQ549601 BX507252 BX494383 BX538129 BG720541 BI677354 CA867090 BM914586 CF529532 AL551080 CB990986 BX644537 NM_004453 F27075 BM995634
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for ETFDH (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5a | · | 5b | · | 5c | · | 5d | · | 5e | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ |
|---|
|
| SP1: | | | | | | | | | - | | - | | | | | | - | | - | | - | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | - | | - | | - | | | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | - | | - | | - | | - | | - | | - | | - | | - | | - | | - | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | - | | - | | | | | | | | - | | - | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| ExUns: | 15 |
|---|
|
| SP1: | | | |
| SP2: | | | |
| SP3: | | | |
| SP4: | | | |
| SP5: | | |
ECgene alternative splicing isoforms for ETFDH
|
Expression
for ETFDH gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ETFDH expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: TGATATTAAA
About this image
See ETFDH Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ETFDH
SOURCE GeneReport for Unigene cluster: Hs.155729
SABiosciences Expression via Pathway-Focused PCR Array including ETFDH:
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETFDH
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ETFDH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETFDH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETFDH | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETFDH |
Orthologs
for ETFDH gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ETFDH gene from 11/38 species (see all 38) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Etfdh1 , 5 |
electron transferring flavoprotein, dehydrogenase1, 5 |
88.64(n)1
92.53(a)1 |
|
3 (34.91 cM)5
668411 NM_025794.21 NP_080070.21
796037885 |
chicken
(Gallus gallus) |
Aves |
ETFDH1 |
electron-transferring-flavoprotein dehydrogenase |
78.95(n)
86.64(a) |
|
428724 NM_001031534.1 NP_001026705.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ETFDH6 |
-- |
84(a) |
1 ↔ 1 |
5(128359013-128374221) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.190712 |
Xenopus laevis transcribed sequence with moderate similarity more |
83.43(n) |
|
BI675385.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
wufa05a112 |
wufa05a11 |
74.86(n) |
|
334845 CA474423.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG121401 , 3 |
electron-transferring-flavoprotein
dehydrogenase3
CG121401 |
66(a)3
60.95(n)1
66.55(a)1 |
|
46C43
360311 NM_136692.11 NP_610536.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
let-7211 , 3 |
YAAS3
Protein LET-7211 |
63(a)3
62(n)1
63.75(a)1 |
|
III(6516639-6518668)3
1759161 NM_066014.51 NP_498415.21 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
CIR2(YOR356W)4
CIR21 |
Putative ortholog of human electron transfer flavoprotein more4
Cir2p1 |
57.58(n)1
55.23(a)1 |
|
15(1007221-1009116)4
8545381, 4 NP_015001.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ETFQO1 |
electron-transferring-flavoprotein dehydrogenase |
59.91(n)
56.1(a) |
|
818941 NM_129901.3 NP_181868.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.157672 |
Oryza sativa (japonica cultivar-group) cDNA cloneJ more |
72.17(n) |
|
NM_197352.1 |
ENSEMBL Gene Tree for ETFDH (if available)
TreeFam Gene Tree for ETFDH (if available) |
Paralogs
for ETFDH gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ETFDH gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Human Gene Mutation Database (HGMD): ETFDH
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ETFDH |
|
Disorders
/ Diseases
for ETFDH gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ETFDH for disorders About GeneDecksing
OMIM gene information: 231675
OMIM disorders: 231680
UniProtKB/Swiss-Prot: ETFD_HUMAN, Q16134
Defects in ETFDH are the cause of glutaric aciduria type 2C (GA2C) [MIM:231680]. GA2C is an autosomalrecessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multipleacyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic,ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids
12  diseases for ETFDH: About MalaCardsisobutyryl-coa dehydrogenase deficiency glutaricaciduria, type iic acyl-coa dehydrogenase glutaric acidemia type ii
glutaricaciduria carnitine deficiency developmental disabilities metabolic disorders
reye syndrome ichthyosis myopathy hepatitis
3 diseases from the University of Copenhagen DISEASES database for ETFDH:Systemic primary carnitine deficiency disease Neutral lipid storage disease Reye syndrome 5 Novoseek disease relationships for ETFDH gene About this table
Genatlas disease: ETFDH glutaric acidemia,type II
Human Genome Epidemiology (HuGE) Navigator: ETFDH (4 documents)
Export disorders for ETFDH gene to outside databases
|
Publications
for ETFDH gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ETFDH gene, integrated from 9 sources (see all 67):
(articles sorted by number of sources associating them with ETFDH) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular cloning and expression of a cDNA encoding human electron transfer flavoprotein-ubiquinone oxidoreductase. (PubMed id 8306995)1, 2, 9 Goodman S.I....Frerman F.E. (1994)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Novel mutations in ETFDH gene in Chinese patients wit h riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency. (PubMed id 19265687)1, 9 Law L.K....Lam C.W. (2009)
- High resolution melting analysis facilitates mutation screening of ETFDH gene: applications in riboflavin-responsive multiple acyl-C oA dehydrogenase deficiency. (PubMed id 20138856)1, 9 Er T.K....Jong Y.J. (2010)
- Structure of electron transfer flavoprotein-ubiquinone oxidoreductase and electron transfer to the mitochondrial ubiquinone pool. (PubMed id 17050691)1, 9 Zhang J....Kim J.J. (2006)
- Alternative quinone substrates and inhibitors of human electron-transfer flavoprotein-ubiquinone oxidoreductase. (PubMed id 14640977)1, 9 Simkovic M. and Frerman F.E. (2004)
- Electron spin relaxation enhancement measurements of interspin distances in human, porcine, and Rhodobacter electron transfer flavoprotein-ubiquinone oxidoreductase (ETF-QO). (PubMed id 18037314)1, 9 Fielding A.J....Eaton S.S. (2008)
- The myopathic form of coenzyme Q10 deficiency is caused by mutations in the electron-transferring-flavoprotein dehydrogenase (ETFDH) gene. (PubMed id 17412732)1, 9 Gempel K....Horvath R. (2007)
- ETFDH mutations, CoQ10 levels, and respiratory chain activities in patients with riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency. (PubMed id 19249206)1, 9 Liang W.C....Nishino I. (2009)
- Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: the mouse homologs of genes responsible for glutaric acidemia type II in human. (PubMed id 8617498)1, 9 White R.A....Koeller D.M. (1996)
|
External Searches for ETFDH gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
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Genome Databases showing ETFDH gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
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Other Databases showing ETFDH gene
(According to HUGE)
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Specialized Databases showing ETFDH gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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| Name | Description |
| PharmGKB entry for ETFDH | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ETFDH |
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| Patent Information for ETFDH gene:
Search GeneIP for patents involving ETFDH
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ETFDH gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ETFDH | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ETFDH | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETFDH | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ETFDH | | OriGene 3'-UTR Clone for ETFDH | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETFDH | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETFDH | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ETFDH | | OriGene Custom Protein Services for ETFDH | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ETFDH | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ETFDH | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETFDH | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ETFDH | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETFDH | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETFDH |
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| | | | Search Tocris compounds for ETFDH |
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 | | | ETFDH Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETFDH |
|  |  |  | | | | ThermoFisher Antibodies for ETFDH |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETFDH |
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