ETFA Gene
protein-coding GIFtS: 62
GCID: GC15M076508
|
|
electron-transfer-flavoprotein, alpha polypeptide
| |
Aliases
for ETFA gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Electron-Transfer-Flavoprotein, Alpha Polypeptide1 2 | | Electron Transfer Flavoprotein Alpha-Subunit2 | | GA21 2 5 | | Electron Transfer Flavoprotein Subunit Alpha, Mitochondrial2 | | MADD1 2 5 | | Electron Transfer Flavoprotein, Alpha Polypeptide2 | | EMA1 2 | | Glutaric Aciduria II2 | | Alpha-ETF3 | | Alpha-ETF3 |
Export aliases for ETFA gene to outside databasesPrevious GC identifers: GC15M072396 GC15M069598 GC15M074084 GC15M074224 GC15M074295 GC15M053265 |
Summaries
for ETFA gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for ETFA:
ETFA participates in catalyzing the initial step of the mitochondrial fatty acid beta-oxidation. It shuttles electronsbetween primary flavoprotein dehydrogenases and the membrane-bound electron transfer flavoprotein ubiquinoneoxidoreductase. Defects in electron-transfer-flavoprotein have been implicated in type II glutaricaciduria in whichmultiple acyl-CoA dehydrogenase deficiencies result in large excretion of glutaric, lactic, ethylmalonic, butyric,isobutyric, 2-methyl-butyric, and isovaleric acids. Two transcript variants encoding different isoforms have beenfound for this gene. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: ETFA_HUMAN, P13804Function: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases,including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to themain mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase)
Gene Wiki entry for ETFA
|
Genomic Views
for ETFA gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000015.9 NC_018926.1 NT_010194.17
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the ETFA gene promoter:
HTF POU3F2 (N-Oct-5a) POU3F2 (N-Oct-5b) POU3F2 Tal-1beta POU2F1 POU2F1a Cart-1 ITF-2 ATF6
Other transcription factors
Search SABiosciences Chromatin IP Primers for ETFA
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETFA |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 15q23-q25 Ensembl cytogenetic band: 15q24.3 HGNC cytogenetic band: 15q23-q25ETFA Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 15 GeneLoc Exon Structure GeneLoc location for GC15M076508: view genomic region
(about GC identifiers)
Start:
|
76,507,696 bp from pter |
End:
|
76,603,813 bp from pter |
Size:
|
96,118 bases |
Orientation:
|
minus strand |
|
Proteins
for ETFA gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: ETFA_HUMAN, P13804 (See
protein sequence)Recommended Name: Electron transfer flavoprotein subunit alpha, mitochondrial precursor Size: 333 amino acids; 35080 Da
Cofactor: Binds 1 FAD per dimer
Subunit: Heterodimer of an alpha and a beta subunit
Subcellular location: Mitochondrion matrix
4 PDB 3D structures from  and Proteopedia  for ETFA:1EFV (3D)
1T9G (3D)
2A1T (3D)
2A1U (3D)
Secondary accessions: B4DT43 Q53XN3Alternative splicing: 2 isoforms: P13804-1 P13804-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for ETFA: NX_P13804
Post-translational modifications:
The N-terminus is blocked1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P13804
ETFA Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_000117.1 NP_001121188.1
ENSEMBL proteins: ENSP00000452762 ENSP00000399273 ENSP00000267950 ENSP00000458001 ENSP00000453098 ENSP00000452659 ENSP00000454194 ENSP00000453345 ENSP00000453422 ENSP00000452942 ENSP00000453017 ENSP00000452777 ENSP00000453753 Reactome Protein details: P13804
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
ETFA for ontologies About GeneDecksing
ETFA Antibody Products:
Assay Products for ETFA: |
Protein
Domains /
Families
for ETFA gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
ETFA for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P13804ProtoNet protein and cluster: P13804 2 Blocks protein families: IPB001308 Electron transfer flavoprotein IPB014731 Electron transfer flavoprotein
UniProtKB/Swiss-Prot: ETFA_HUMAN, P13804Similarity: Belongs to the ETF alpha-subunit/FixB family |
Function
for ETFA gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: ETFA_HUMAN, P13804Function: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases,including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to themain mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase) Genatlas biochemistry entry for ETFA:electron transfer flavoprotein,alpha (32kDa),with the unstable variant T171I overreprinted in ACADVL deficient patientswith mild childhood presentation
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETFA (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETFA (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): ETFA (NM_000126) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ETFA | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETFA |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETFA |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
ETFA for ontologies About GeneDecksing
3 GenomeRNAi human phenotypes for ETFA:
|
Pathways & Interactions
for ETFA gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. | | | 2 | Metabolism | |
Pathway sources
See GeneCards unified pathways
Show all pathways
4 
Reactome Pathways for ETFA
ETFA for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for ETFA
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/321 Interacting proteins for ETFA (P138042, 3 ENSP000002679504) via UniProtKB, MINT, STRING, and/or I2D (see all 321)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0022904 | respiratory electron transport chain |
TAS | -- | | GO:0044281 | small molecule metabolic process |
TAS | -- | | GO:0055114 | oxidation-reduction process |
-- | -- |
ETFA for ontologies About GeneDecksing
|
Drugs & Compounds
for ETFA gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
ETFA for compounds About GeneDecksing
 Browse Tocris compounds for ETFA
1 HMDB Compound for ETFA About this table
| Compound | Synonyms |
CAS
# | PubMed Ids |
|---|
| FAD | 1H-Purin-6-amine flavin dinucleotide (see all 21) | 146-14-5 | -- |
1 Novoseek chemical compound relationship for ETFA gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| acyl-coa |
66.9 |
3 |
19265687 (1), 16527485 (1) |
Search CenterWatch for drugs/clinical trials and news about ETFA
|
Transcripts
for ETFA gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for ETFA gene (2 alternative transcripts): NM_000126.3 NM_001127716.1 Unigene Cluster for ETFA: Electron-transfer-flavoprotein, alpha polypeptide Hs.39925 [show with all ESTs]Unigene Representative Sequence: AK29297918/20 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 20): ENST00000557943(uc002bbt.2 uc010bkq.1) ENST00000433983 ENST00000557975
ENST00000267950 ENST00000565910 ENST00000560179 ENST00000560726 ENST00000559602
ENST00000559973 ENST00000560595 ENST00000560899 ENST00000559075 ENST00000560044
ENST00000560816 ENST00000558803 ENST00000559758 ENST00000560345 ENST00000559386
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETFA (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETFA (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): ETFA (NM_000126) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for ETFA | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETFA |
Additional cDNA sequence: AK292979.1 AK300044.1 BC015526.1 BC029995.1 BC034156.1 BC095457.1 BT009796.1 J04058.1 24/28 DOTS entries (see all 28): DT.452682 DT.100845847 DT.100845842 DT.121019654 DT.100845838 DT.121019723 DT.100845840 DT.97862432 DT.100845841 DT.86853568 DT.100845839 DT.100845844 DT.102833401 DT.449350 DT.92452763 DT.95362494 DT.121019693 DT.92452760 DT.100717416 DT.100845833 DT.100845834 DT.121019667 DT.121019669 DT.92452756 24/444 AceView cDNA sequences (see all 444): CB141761 CF127663 BU195820 BC029995 BG742919 BI767335 BM451068 BM452381 CF139853 BU657307 CR592726 BG698699 NM_000126 BM804215 AI056817 BQ893479 CB139263 CB138162 CR608419 AV660860 CD695625 BM745538 BQ216165 BQ436599
GeneLoc Exon Structure
5 Alternative Splicing Database (ASD) splice patterns (SP) for ETFA About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | · | 3c | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | ^ | 10 | ^ | 11a | · | 11b | ^ | 12a | · | 12b | · | 12c |
|---|
|
| SP1: | | | | | | | - | | | | | | | | | | | | | | - | | | | - | | - | | - | | | | | | | | | | |
| SP2: | | | | | | | - | | | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for ETFA
|
Expression
for ETFA gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| ETFA expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GAGAGCTACA
About this image
See ETFA Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for ETFA
SOURCE GeneReport for Unigene cluster: Hs.39925
SABiosciences Custom PCR Arrays for ETFA
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETFA
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat ETFA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETFA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETFA | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETFA |
Orthologs
for ETFA gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the last universal common ancestor (LUCA).
Orthologs for ETFA gene from 11/41 species (see all 41) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Etfa1 , 5 |
electron transferring flavoprotein, alpha polypeptide1, 5 |
91.69(n)1
95.8(a)1 |
|
9 (30.13 cM)5
1108421 NM_145615.41 NP_663590.31
554545085 |
chicken
(Gallus gallus) |
Aves |
ETFA1 |
electron-transfer-flavoprotein, alpha polypeptide |
78.47(n)
84.78(a) |
|
415353 NM_001030543.1 NP_001025714.1 |
lizard
(Anolis carolinensis) |
Reptilia |
ETFA6 |
-- |
85(a) |
1 ↔ 1 |
AAWZ02039250(550-6297) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.242462 |
Xenopus laevis transcribed sequence with moderate similarity more |
74.56(n) |
|
CA793847.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
etfa2 |
electron-transfer-flavoprotein, alpha polypeptide |
74.29(n) |
|
325724 BC047845.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
wal1 , 3 |
electron carrier3
walrus1 |
70(a)3
63.31(n)1
71.07(a)1 |
|
362521 NM_057627.31 NP_476975.11 |
worm
(Caenorhabditis elegans) |
Secernentea |
CELE_F27D4.11 |
Protein F27D4.1 |
62.94(n)
64.54(a) |
|
172535 NM_059745.4 NP_492146.1 |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
AIM45(YPR004C)4
AIM451 |
Putative ortholog of mammalian electron transfer flavoprotein more4
Aim45p1 |
52.34(n)1
47.77(a)1 |
|
16(565041-564007)4
8561121, 4 NP_015329.11, 4 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
ETFALPHA1 |
Electron transfer flavoprotein subunit alpha |
56.99(n)
52.05(a) |
|
841516 NM_103974.5 NP_175507.1 |
rice
(Oryza sativa) |
Liliopsida |
Os.140842 |
Oryza sativa (japonica cultivar-group) cDNA clone0 more |
69.88(n) |
|
AK061773.1 |
ENSEMBL Gene Tree for ETFA (if available)
TreeFam Gene Tree for ETFA (if available) |
Paralogs
for ETFA gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for ETFA gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 15 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for ETFA (76507696 - 76603813 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for ETFA: --
Human Gene Mutation Database (HGMD): ETFA
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ETFA |
|
Disorders
/ Diseases
for ETFA gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
ETFA for disorders About GeneDecksing
OMIM gene information: 608053
OMIM disorders: 231680
UniProtKB/Swiss-Prot: ETFA_HUMAN, P13804
Defects in ETFA are the cause of glutaric aciduria type 2A (GA2A) [MIM:231680]; also known as glutaricaciduriaIIA. GA2A is an autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It ischaracterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid,but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids
15  diseases for ETFA: About MalaCardsacyl-coa dehydrogenase glutaricaciduria glutaricaciduria, type iia glutaric acidemia type ii
diffuse large b-cell lymphoma b-cell lymphomas benign mesothelioma gangliosidosis
celiac disease hemangioma myopathy tuberculosis
carcinoma hepatitis mycobacterium tuberculosis
1 disease from the University of Copenhagen DISEASES database for ETFA:Gangliosidosis 1 Novoseek disease relationship for ETFA gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| shock |
10.9 |
2 |
17196136 (1), 17244485 (1) |
Genatlas disease: ETFA glutaric aciduria IIA,early onset
Human Genome Epidemiology (HuGE) Navigator: ETFA (2 documents)
Export disorders for ETFA gene to outside databases
|
Publications
for ETFA gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for ETFA gene, integrated from 9 sources (see all 47):
(articles sorted by number of sources associating them with ETFA) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Molecular characterization of variant alpha-subunit of electron transfer flavoprotein in three patients with glutaric acidemia type II -- and identification of glycine substitution for valine-157 in the sequence of the precursor, producing an unstable mature protein in a patient. (PubMed id 1882842)1, 2, 9 Indo Y.... Tanaka K. (1991)
- Clear relationship between ETF/ETFDH genotype and phenotype in patients with multiple acyl-CoA dehydrogenation deficiency. (PubMed id 12815589)1, 2, 9 Olsen R.K.J....Gregersen N. (2003)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- A polymorphic variant in the human electron transfer flavoprotein alpha-chain (alpha-T171) displays decreased thermal stability and is overrepresented in very-long-chain acyl-CoA dehydrogenase-deficient patients with mild childhood presentation. (PubMed id 10356313)1, 2 Bross P....Gregersen N. (1999)
- Three-dimensional structure of human electron transfer flavoprotein to 2.1-A resolution. (PubMed id 8962055)1, 2 Roberts D.L.... Kim J.-J.P. (1996)
- Glutaric acidemia type II. Heterogeneity in beta-oxidation flux, polypeptide synthesis, and complementary DNA mutations in the alpha subunit of electron transfer flavoprotein in eight patients. (PubMed id 1430199)1, 2 Freneaux E.... Rhead W. (1992)
- Molecular cloning and nucleotide sequence of cDNAs encoding the alpha-subunit of human electron transfer flavoprotein. (PubMed id 3170610)1, 2 Finocchiaro G.... Tanaka K. (1988)
- Assignment of Etfdh, Etfb, and Etfa to chromosomes 3, 7, and 13: the mouse homologs of genes responsible for glutaric acidemia type II in human. (PubMed id 8617498)1, 9 White R.A....Koeller D.M. (1996)
- Electron transfer flavoprotein deficiency: functional and molecular aspects. (PubMed id 16510302)1, 9 Schiff M....Vianey-Saban C. (2006)
- Genome-wide association analysis implicates the involv ement of eight loci with response to tocilizumab for the treatment of rheumatoid arthritis. (PubMed id 22491018)1 Wang J....Platt A. (2012)
|
External Searches for ETFA gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing ETFA gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
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Other Databases showing ETFA gene
(According to HUGE)
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Specialized Databases showing ETFA gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
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| Name | Description |
| PharmGKB entry for ETFA | Pharmacogenomics, SNPs, Pathways | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/ETFA |
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About This Section
| Patent Information for ETFA gene:
Search GeneIP for patents involving ETFA
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
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Products
for ETFA gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for ETFA | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for ETFA | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for ETFA | | | OriGene Protein Over-expression Lysate for ETFA | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for ETFA | | OriGene 3'-UTR Clone for ETFA | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for ETFA | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for ETFA | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for ETFA | | OriGene Custom Protein Services for ETFA | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat ETFA | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing ETFA | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat ETFA | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat ETFA | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat ETFA | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat ETFA |
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| | | | Search Tocris compounds for ETFA |
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 | | | ETFA Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ETFA |
|  |  |  | | | | ThermoFisher Antibodies for ETFA |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ETFA |
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