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Aliases for ESRG Gene

Subcategory (RNA class) for ESRG Gene

non-coding RNA

Quality Score for this RNA gene is


Aliases for ESRG Gene

  • Embryonic Stem Cell Related (Non-Protein Coding) 2 3 5
  • HESRG 3 4
  • Human Embryonic Stem Cell Related Gene 2
  • Embryonic Stem Cell Related Protein 3
  • Human Embryonic Stem Cell Related 3
  • HES Cell-Related Gene Protein 4

External Ids for ESRG Gene

Previous GeneCards Identifiers for ESRG Gene

  • GC03M054714

Summaries for ESRG Gene

GeneCards Summary for ESRG Gene

ESRG (Embryonic Stem Cell Related (Non-Protein Coding)) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with ESRG include Germinoma.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ESRG Gene

Genomics for ESRG Gene

Regulatory Elements for ESRG Gene

Enhancers for ESRG Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around ESRG on UCSC Golden Path with GeneCards custom track

Genomic Location for ESRG Gene

54,632,122 bp from pter
54,639,857 bp from pter
7,736 bases
Minus strand

Genomic View for ESRG Gene

Genes around ESRG on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ESRG Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ESRG Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ESRG Gene

Proteins for ESRG Gene

  • Protein details for ESRG Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Embryonic stem cell-related gene protein
    Protein Accession:

    Protein attributes for ESRG Gene

    222 amino acids
    Molecular mass:
    24186 Da
    Quaternary structure:
    No Data Available
    • Sequence=ABD92927.1; Type=Erroneous translation; Note=Wrong choice of frame.; Evidence={ECO:0000305};

neXtProt entry for ESRG Gene

Proteomics data for ESRG Gene at MOPED

Post-translational modifications for ESRG Gene

No Post-translational modifications

No data available for DME Specific Peptides for ESRG Gene

Domains & Families for ESRG Gene

Gene Families for ESRG Gene

Protein Domains for ESRG Gene


Suggested Antigen Peptide Sequences for ESRG Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ESRG: view

No data available for UniProtKB/Swiss-Prot for ESRG Gene

Function for ESRG Gene

Molecular function for ESRG Gene

UniProtKB/Swiss-Prot Induction:
Down-regulated during differentiation of ES cells.

No data available for Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ESRG Gene

Localization for ESRG Gene

Subcellular locations from UniProtKB/Swiss-Prot for ESRG Gene

No data available for Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ESRG Gene

Pathways & Interactions for ESRG Gene

SuperPathways for ESRG Gene

No Data Available

Interacting Proteins for ESRG Gene

Gene Ontology (GO) - Biological Process for ESRG Gene


No data available for Pathways by source and SIGNOR curated interactions for ESRG Gene

Drugs & Compounds for ESRG Gene

No Compound Related Data Available

Transcripts for ESRG Gene

mRNA/cDNA for ESRG Gene

(2) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for ESRG Gene

Embryonic stem cell related (non-protein coding):
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for ESRG Gene

No ASD Table

Relevant External Links for ESRG Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ESRG Gene

mRNA expression in normal human tissues for ESRG Gene

mRNA differential expression in normal tissues according to GTEx for ESRG Gene

This gene is overexpressed in Cervix - Ectocervix (x21.7) and Vagina (x15.1).

SOURCE GeneReport for Unigene cluster for ESRG Gene Hs.720658

mRNA Expression by UniProt/SwissProt for ESRG Gene

Tissue specificity: Expressed only in fetal ovary and in undifferentiated ES cells.
genes like me logo Genes that share expression patterns with ESRG: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for ESRG Gene

Orthologs for ESRG Gene

Evolution for ESRG Gene

Gene Tree for ESRG (if available)
Gene Tree for ESRG (if available)

No data available for Orthologs for ESRG Gene

Paralogs for ESRG Gene

No data available for Paralogs for ESRG Gene

Variants for ESRG Gene

Structural Variations from Database of Genomic Variants (DGV) for ESRG Gene

Variant ID Type Subtype PubMed ID
nsv517851 CNV Gain 19592680
nsv834700 CNV Gain 17160897
nsv525644 CNV Gain 19592680

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Variation tolerance and Relevant External Links for ESRG Gene

Disorders for ESRG Gene

MalaCards: The human disease database

(1) MalaCards diseases for ESRG Gene - From: GeneCards

Disorder Aliases PubMed IDs
  • pineal germinoma
- elite association - COSMIC cancer census association via MalaCards
Search ESRG in MalaCards View complete list of genes associated with diseases

Relevant External Links for ESRG

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with ESRG: view

No data available for UniProtKB/Swiss-Prot and Genatlas for ESRG Gene

Publications for ESRG Gene

  1. Transcriptional profiling of human embryonic stem cells and embryoid bodies identifies HESRG, a novel stem cell gene. (PMID: 17803967) Zhao M. … Yao K. (Biochem. Biophys. Res. Commun. 2007) 2 3 4 67
  2. HESRG: a novel biomarker for intracranial germinoma and embryonal carcinoma. (PMID: 21861197) Wanggou S. … Ren C. (J. Neurooncol. 2012) 2 3
  3. Identification, expression and subcellular localization of ESRG. (PMID: 23628413) Li G. … Jiang X. (Biochem. Biophys. Res. Commun. 2013) 3

Products for ESRG Gene

Sources for ESRG Gene