External Ids for ESM1 Gene
Previous GeneCards Identifiers for ESM1 Gene
This gene encodes a secreted protein which is mainly expressed in the endothelial cells in human lung and kidney tissues. The expression of this gene is regulated by cytokines, suggesting that it may play a role in endothelium-dependent pathological disorders. The transcript contains multiple polyadenylation and mRNA instability signals. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2008]
GeneCards Summary for ESM1 Gene
ESM1 (Endothelial Cell-Specific Molecule 1) is a Protein Coding gene. Among its related pathways are Gastric cancer network 1. GO annotations related to this gene include integrin binding and hepatocyte growth factor receptor binding.
UniProtKB/Swiss-Prot for ESM1 Gene
Involved in angiogenesis; promotes angiogenic sprouting. May have potent implications in lung endothelial cell-leukocyte interactions.