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ERMN Gene

protein-coding   GIFtS: 51
GCID: GC02M158175

Ermin, ERM-Like Protein

(Previous name: KIAA1189)
(Previous symbol: KIAA1189)
  Search for ERMN
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Ermin, ERM-Like Protein1 2
KIAA11891 2 3 5
JN2 3 5
ermin1 2
juxtanodin1 2
Juxtanodin3

External Ids:    HGNC: 292081   Entrez Gene: 574712   Ensembl: ENSG000001365417   OMIM: 6100725   UniProtKB: Q8TAM63   

Export aliases for ERMN gene to outside databases

Previous GC identifers: GC02M157884 GC02M150060


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for ERMN Gene:
ERMN (ermin, ERM-like protein) is a protein-coding gene. GO annotations related to this gene include actin filament binding.

UniProtKB/Swiss-Prot: ERMIN_HUMAN, Q8TAM6
Function: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of
myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role
in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the
maintenance and plasticity of related structures in the mature CNS (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000002.11  NC_018913.2  NT_005403.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the ERMN gene promoter:
         FOXF2   aMEF-2   CUTL1   FOXL1   C/EBPalpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): ERMN promoter sequence
   Search Chromatin IP Primers for ERMN

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat ERMN


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2q24.1   Ensembl cytogenetic band:  2q24.1   HGNC cytogenetic band: 2q24

ERMN Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
ERMN gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M158175:  view genomic region     (about GC identifiers)

Start:
158,175,125 bp from pter      End:
158,184,225 bp from pter
Size:
9,101 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: ERMIN_HUMAN, Q8TAM6 (See protein sequence)
Recommended Name: Ermin  
Size: 284 amino acids; 32783 Da
Subunit: Binds actin (By similarity)
Sequence caution: Sequence=BAA86503.1; Type=Erroneous initiation;
Secondary accessions: B4DKA6 Q9ULN1
Alternative splicing: 2 isoforms:  Q8TAM6-1   Q8TAM6-2   

Explore the universe of human proteins at neXtProt for ERMN: NX_Q8TAM6

Explore proteomics data for ERMN at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See ERMN Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_001009959.1  NP_065762.1  

    ENSEMBL proteins: 
     ENSP00000387047   ENSP00000380453   ENSP00000387339   ENSP00000410646   ENSP00000398149  
     ENSP00000389595   ENSP00000387049   ENSP00000387325   ENSP00000410934   ENSP00000438397  

    ERMN Human Recombinant Protein Products:

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    Novus Biologicals ERMN Protein
    Novus Biologicals ERMN Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for ERMN 

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    LSBio Antibodies in human, mouse, rat for ERMN

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    Search eBioscience for ELISAs for ERMN 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR008954 Moesin_tail

    Graphical View of Domain Structure for InterPro Entry Q8TAM6

    ProtoNet protein and cluster: Q8TAM6


    Find genes that share domains with ERMN           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: ERMIN_HUMAN, Q8TAM6
    Function: Plays a role in cytoskeletal rearrangements during the late wrapping and/or compaction phases of
    myelinogenesis as well as in maintenance and stability of myelin sheath in the adult. May play an important role
    in late-stage oligodendroglia maturation, myelin/Ranvier node formation during CNS development, and in the
    maintenance and plasticity of related structures in the mature CNS (By similarity)

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding ----
    GO:0051015actin filament binding IEA--
         
    Find genes that share ontologies with ERMN           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for ERMN:
     Wnt reporter upregulated 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for ERMN
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for ERMN

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for ERMN
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for ERMN

    miRNA
    Products:
        
    miRTarBase miRNAs that target ERMN:
    hsa-mir-10a-5p (MIRT047642), hsa-mir-1 (MIRT023843)

    Block miRNA regulation of human, mouse, rat ERMN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ERMN (see all 29):
    hsa-miR-320a hsa-miR-181c hsa-miR-376b hsa-miR-4263 hsa-miR-4305 hsa-miR-139-5p hsa-miR-944 hsa-miR-3923
    SwitchGear 3'UTR luciferase reporter plasmidERMN 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for ERMN
    Predesigned siRNA for gene silencing in human, mouse, rat ERMN

    Gene Editing
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    GenScript: all cDNA clones in your preferred vector (see all 2): ERMN (NM_020711)
    Sino Biological Human cDNA Clone for ERMN
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERMN

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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERMN


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    ERMIN_HUMAN, Q8TAM6: Cytoplasm, cytoskeleton (By similarity)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    nucleus3
    cytoskeleton2
    cytosol2

    Gene Ontology (GO): Selected cellular component terms (see all 9):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IDA--
    GO:0005856cytoskeleton IEA--
    GO:0005938cell cortex IDA--
    GO:0030175filopodium IEA--
    GO:0033269internode region of axon IDA--

    Find genes that share ontologies with ERMN           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for ERMN
    Interactions:

        Search GeneGlobe Interaction Network for ERMN

    STRING Interaction Network Preview (showing 5 interactants - click image to see 14)

    Selected Interacting proteins for ERMN (Q8TAM63 ENSP000003804534) via UniProtKB, MINT, STRING, and/or I2D (see all 16)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    JUNP054123I2D: score=2 
    CTNNB1P352223I2D: score=1 
    RPL8ENSP000002625844STRING: ENSP00000262584
    DKC1ENSP000003585634STRING: ENSP00000358563
    TRUB1ENSP000002987464STRING: ENSP00000298746
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001763morphogenesis of a branching structure IEA--
    GO:0007015actin filament organization IDA--
    GO:0008360regulation of cell shape IDA--
    GO:0031344regulation of cell projection organization IDA--

    Find genes that share ontologies with ERMN           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for ERMN (ERMIN)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for ERMN gene (2 alternative transcripts): 
    NM_001009959.1  NM_020711.1  

    Unigene Cluster for ERMN:

    Ermin, ERM-like protein
    Hs.443894  [show with all ESTs]
    Unigene Representative Sequence: NM_020711
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000410096(uc010zcj.2 uc002tzh.3 uc010zck.2) ENST00000397283(uc002tzi.3)
    ENST00000409395 ENST00000420719 ENST00000420317 ENST00000411762 ENST00000409216
    ENST00000409925 ENST00000419116 ENST00000535935
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat ERMN using miScript Target Protectors
    Selected qRT-PCR Assays for microRNAs that regulate ERMN (see all 29):
    hsa-miR-320a hsa-miR-181c hsa-miR-376b hsa-miR-4263 hsa-miR-4305 hsa-miR-139-5p hsa-miR-944 hsa-miR-3923
    SwitchGear 3'UTR luciferase reporter plasmidERMN 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for ERMN
    Predesigned siRNA for gene silencing in human, mouse, rat ERMN
    Clone
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    OriGene clones in human, mouse for ERMN (see all 11)
    OriGene ORF clones in mouse, rat for ERMN
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): ERMN (NM_020711)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for ERMN
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat ERMN
    Primer
    Products:
        
    OriGene qSTAR qPCR primer pairs in human, mouse for ERMN
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat ERMN
      QuantiTect SYBR Green Assays in human, mouse, rat ERMN
      QuantiFast Probe-based Assays in human, mouse, rat ERMN

    Additional mRNA sequence: 

    AB033015.1 AK295844.1 AK296477.1 AK296489.1 BC026345.1 DQ334271.1 

    8 DOTS entries:

    DT.101973982  DT.121006279  DT.121006269  DT.209970  DT.121006264  DT.121006278  DT.121006262  DT.121006277 

    Selected AceView cDNA sequences (see all 64):

    AA651956 BX279782 BI819519 BX449196 AV703122 N50020 AA761058 BX952057 
    N50208 BI753117 AB033015 BC026345 N54676 BI602290 BI598234 BI602041 
    BI550933 BI544353 CD102785 N49084 BI603436 AA736604 CK001919 AA291064 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for ERMN (see all 10)    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3a · 3b · 3c · 3d · 3e ^ 4a · 4b ^ 5a · 5b · 5c ^ 6a · 6b ^ 7a · 7b · 7c · 7d · 7e · 7f
    SP1:        -     -     -     -     -                 -     -                 -     -     -                                       
    SP2:                    -     -     -                 -     -                 -     -     -                                       
    SP3:                    -     -     -     -           -     -                 -     -     -                                       
    SP4:                                                  -     -                 -           -                                       
    SP5:                                                  -     -                 -     -     -                                       


    ECgene alternative splicing isoforms for ERMN

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    ERMN expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ATTTTTTGTT
    ERMN Expression
    About this image


    ERMN expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
    ERMN Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    ERMN Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.443894

    UniProtKB/Swiss-Prot: ERMIN_HUMAN, Q8TAM6
    Tissue specificity: Highly expressed in adult and fetal brain. Expressed at intermediate levels in the lung and
    liver

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for ERMN

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for ERMN gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ermn1 , 5 ermin, ERM-like protein1, 5 74.13(n)1
    61.37(a)1
      2 (32.99 cM)5
    777671  NM_029972.31  NP_084248.21 
     580451135 
    chicken
    (Gallus gallus)
    Aves ERMN6
    ermin, ERM-like protein
    33(a)
    1 ↔ 1
    7(35708864-35712432)
    lizard
    (Anolis carolinensis)
    Reptilia ERMN6
    ermin, ERM-like protein
    43(a)
    1 ↔ 1
    GL343254.1(462516-462962)
    African clawed frog
    (Xenopus laevis)
    Amphibia BG812811.12   -- 76.06(n)    BG812811.1 


    ENSEMBL Gene Tree for ERMN (if available)
    TreeFam Gene Tree for ERMN (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for ERMN gene
    12 SIMAP similar genes for ERMN using alignment to 9 protein entries:     ERMIN_HUMAN (see all proteins):
    FLJ16124    FTSJ2    SNRPF    RBP7    PFKFB3    TUBA1C
    COQ5    GALK2    DYNC1LI1    RHBG    C12orf76    GEMIN6

    Find genes that share paralogs with ERMN           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for ERMN (see all 218)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs134304361,2
    C,F,H--158174634(+) TTATTA/TTACTC 2 -- int14Minor allele frequency- T:0.01NS EA 418
    rs1476419111,2
    C--158174659(+) TCTCC-/ATAA  
      TTCTCT
    ATTAT
    2 -- int10--------
    rs1844060811,2
    --158174672(+) CTATTA/GTTACT 2 -- int10--------
    rs1869006831,2
    --158174775(+) AGAAAC/TGATTG 2 -- int10--------
    rs1915095401,2
    --158174799(+) AGCATA/GGTTTA 2 -- int10--------
    rs1847687301,2
    --158174844(+) AAGTTG/TTTCGT 2 -- int10--------
    rs1427685501,2
    --158175013(+) GTGTTC/TTCTTG 2 -- int10--------
    rs1460796261,2
    --158175031(+) AAGAGG/TTATTC 2 -- int10--------
    rs1155110121,2
    F--158175100(+) CTAAAC/GAAAAT 2 -- int11Minor allele frequency- G:0.03WA 118
    rs1894967481,2
    --158175128(+) AATAAA/GGACAC 2 -- ut310--------

    HapMap Linkage Disequilibrium report for ERMN (158175125 - 158184225 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for ERMN:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2518040CNV Deletion19546169
    nsv834432CNV Gain17160897

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing ERMN
    DNA2.0 Custom Variant and Variant Library Synthesis for ERMN

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 610072    OMIM disorders: --


    Find genes that share disorders with ERMN           About GenesLikeMe

    Genetic Association Database (GAD): ERMN
    Human Genome Epidemiology (HuGE) Navigator: ERMN (1 document)

    Export disorders for ERMN gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for ERMN gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with ERMN)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Ermin, a myelinating oligodendrocyte-specific protein that regulates cell morphology. (PubMed id 16421295)1, 2, 3 Brockschnieder D.... Peles E. (J. Neurosci. 2006)
    2. Evidence for genes on chromosome 2 contributing to alcohol dependence with conduct disorder and suicide attempts. (PubMed id 20468071)1, 4 Dick D.M....Bierut L. (Am. J. Med. Genet. B Neuropsychiatr. Genet. 2010)
    3. Juxtanodin: an oligodendroglial protein that promotes cellular arborization and 2',3'-cyclic nucleotide-3'-phosphodiesterase trafficking. (PubMed id 16051705)1, 3 Zhang B....Liang F. (Proc. Natl. Acad. Sci. U.S.A. 2005)
    4. Characterization of cDNA clones selected by the GeneMark analysis from size-fractionated cDNA libraries from human brain. (PubMed id 10574461)1, 2 Hirosawa M.... Ohara O. (DNA Res. 1999)
    5. Human Ermin (hErmin), a new oligodendrocyte-specific cytoskeletal protein related to epileptic seizure. (PubMed id 20934411)1 Wang T....Zhang B. (Brain Res. 2011)
    6. Interactions of pathological hallmark proteins: tubulin polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (J. Biol. Chem. 2011)
    7. Comparison of substrate specificity of the ubiquitin ligases Nedd4 and Nedd4-2 using proteome arrays. (PubMed id 19953087)1 Persaud A....Rotin D. (Mol. Syst. Biol. 2009)
    8. Prefrontal cortex shotgun proteome analysis reveals altered calcium homeostasis and immune system imbalance in schizophrenia. (PubMed id 19165527)1 Martins-de-Souza D....Turck C.W. (Eur Arch Psychiatry Clin Neurosci 2009)
    9. Large-scale proteomics and phosphoproteomics of urinary exosomes. (PubMed id 19056867)1 Gonzales P.A....Knepper M.A. (J. Am. Soc. Nephrol. 2009)
    10. Alterations in oligodendrocyte proteins, calcium homeostasis and new potential markers in schizophrenia anterior temporal lobe are revealed by shotgun proteome analysis. (PubMed id 19034380)1 Martins-de-Souza D....Dias-Neto E. (J Neural Transm 2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 57471 HGNC: 29208 AceView: KIAA1189 Ensembl:ENSG00000136541 euGenes: HUgn57471
    ECgene: ERMN H-InvDB: ERMN

    (According to HUGE)
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    HUGE: KIAA1189

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for ERMN Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for ERMN gene:
    Search GeneIP for patents involving ERMN

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
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