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Aliases for ERICH5 Gene

Aliases for ERICH5 Gene

  • Glutamate Rich 5 2 3 5
  • C8orf47 3 4
  • Chromosome 8 Open Reading Frame 47 2
  • Glutamate-Rich Protein 5 3
  • Glutamate-Rich 5 2

External Ids for ERICH5 Gene

Previous HGNC Symbols for ERICH5 Gene

  • C8orf47

Previous GeneCards Identifiers for ERICH5 Gene

  • GC08P099077

Summaries for ERICH5 Gene

GeneCards Summary for ERICH5 Gene

ERICH5 (Glutamate Rich 5) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERICH5 Gene

Genomics for ERICH5 Gene

Regulatory Elements for ERICH5 Gene

Enhancers for ERICH5 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
- Elite enhancer/Elite enhancer-gene association

Enhancers around ERICH5 on UCSC Golden Path with GeneCards custom track

Promoters for ERICH5 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around ERICH5 on UCSC Golden Path with GeneCards custom track

Genomic Location for ERICH5 Gene

98,064,311 bp from pter
98,093,610 bp from pter
29,300 bases
Plus strand

Genomic View for ERICH5 Gene

Genes around ERICH5 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ERICH5 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ERICH5 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ERICH5 Gene

Proteins for ERICH5 Gene

  • Protein details for ERICH5 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Glutamate-rich protein 5
    Protein Accession:
    Secondary Accessions:
    • G3V1K4
    • Q8N1L8

    Protein attributes for ERICH5 Gene

    374 amino acids
    Molecular mass:
    39936 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for ERICH5 Gene


neXtProt entry for ERICH5 Gene

Post-translational modifications for ERICH5 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for ERICH5 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ERICH5 Gene

Domains & Families for ERICH5 Gene

Protein Domains for ERICH5 Gene


Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ERICH5: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ERICH5 Gene

Function for ERICH5 Gene

genes like me logo Genes that share phenotypes with ERICH5: view

Animal Model Products

CRISPR Products

miRNA for ERICH5 Gene

miRTarBase miRNAs that target ERICH5

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for ERICH5 Gene

Localization for ERICH5 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ERICH5 Gene

Pathways & Interactions for ERICH5 Gene

SuperPathways for ERICH5 Gene

No Data Available

Interacting Proteins for ERICH5 Gene

STRING Interaction Network Preview (showing 1 interactants - click image to see details)
Selected Interacting proteins: ENSP00000315614 Q6P6B1-ERIC5_HUMAN for ERICH5 Gene via STRING IID

Gene Ontology (GO) - Biological Process for ERICH5 Gene


No data available for Pathways by source and SIGNOR curated interactions for ERICH5 Gene

Drugs & Compounds for ERICH5 Gene

No Compound Related Data Available

Transcripts for ERICH5 Gene

mRNA/cDNA for ERICH5 Gene

CRISPR Products

Inhibitory RNA Products

Clone Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ERICH5 Gene

No ASD Table

Relevant External Links for ERICH5 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for ERICH5 Gene

mRNA expression in normal human tissues for ERICH5 Gene

mRNA differential expression in normal tissues according to GTEx for ERICH5 Gene

This gene is overexpressed in Pancreas (x13.3) and Liver (x4.4).

Protein differential expression in normal tissues from HIPED for ERICH5 Gene

This gene is overexpressed in Islet of Langerhans (32.5) and Pancreas (28.1).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for ERICH5 Gene

Protein tissue co-expression partners for ERICH5 Gene

NURSA nuclear receptor signaling pathways regulating expression of ERICH5 Gene:

genes like me logo Genes that share expression patterns with ERICH5: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for ERICH5 Gene

Orthologs for ERICH5 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ERICH5 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia ERICH5 34
  • 76.79 (n)
  • 64.62 (a)
C14H8orf47 35
  • 53 (a)
(Canis familiaris)
Mammalia ERICH5 34
  • 80.23 (n)
  • 64.12 (a)
C8orf47 35
  • 62 (a)
(Mus musculus)
Mammalia BC030476 34
  • 71.85 (n)
  • 53.67 (a)
Erich5 16
BC030476 35
  • 52 (a)
(Rattus norvegicus)
Mammalia LOC681820 34
  • 71.12 (n)
  • 52.37 (a)
(Monodelphis domestica)
Mammalia C8orf47 35
  • 33 (a)
(Pan troglodytes)
Mammalia C8orf47 35
  • 99 (a)
C8H8orf47 34
  • 99.47 (n)
  • 98.93 (a)
Species where no ortholog for ERICH5 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ERICH5 Gene

Gene Tree for ERICH5 (if available)
Gene Tree for ERICH5 (if available)

Paralogs for ERICH5 Gene

No data available for Paralogs for ERICH5 Gene

Variants for ERICH5 Gene

Sequence variations from dbSNP and Humsavar for ERICH5 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs7833473 - 98,089,193(+) AAGCC(A/G)TCCTC intron-variant, reference, missense
rs35368005 - 98,089,748(+) GCAGC(A/C)ACTTC intron-variant, reference, missense
rs11994440 - 98,089,877(+) ATTCC(A/G)TAAAA intron-variant, reference, missense
rs1001908 -- 98,067,910(+) ATACT(A/G)TATAT intron-variant
rs1038004 -- 98,065,909(-) AGCGG(A/C)TGAGC intron-variant

Structural Variations from Database of Genomic Variants (DGV) for ERICH5 Gene

Variant ID Type Subtype PubMed ID
dgv250n6 CNV deletion 16902084
esv2663748 CNV deletion 23128226
esv2737347 CNV deletion 23290073
esv3618145 CNV loss 21293372
nsv1031795 CNV loss 25217958
nsv1142535 CNV tandem duplication 24896259
nsv398164 CNV deletion 16902084
nsv465745 CNV gain 19166990
nsv465746 CNV gain 19166990
nsv465747 CNV gain 19166990
nsv611805 CNV gain 21841781
nsv611806 CNV gain 21841781
nsv611807 CNV gain 21841781
nsv831405 CNV gain 17160897

Variation tolerance for ERICH5 Gene

Residual Variation Intolerance Score: 59.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.58; 44.84% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ERICH5 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERICH5 Gene

Disorders for ERICH5 Gene

Relevant External Links for ERICH5

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for ERICH5 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ERICH5 Gene

Publications for ERICH5 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4 65
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 2 3 65
  3. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3 65
  4. A Dynamic Protein Interaction Landscape of the Human Centrosome-Cilium Interface. (PMID: 26638075) Gupta G.D. … Pelletier L. (Cell 2015) 3 65
  5. Common variants at 5q22 associate with pediatric eosinophilic esophagitis. (PMID: 20208534) Rothenberg M.E. … Hakonarson H. (Nat. Genet. 2010) 3 65

Products for ERICH5 Gene

Sources for ERICH5 Gene