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Aliases for ERICH4 Gene

Aliases for ERICH4 Gene

  • Glutamate Rich 4 2 3 5
  • C19orf69 3 4
  • Chromosome 19 Open Reading Frame 69 2
  • Glutamate-Rich Protein 4 3
  • Glutamate-Rich 4 2

External Ids for ERICH4 Gene

Previous HGNC Symbols for ERICH4 Gene

  • C19orf69

Previous GeneCards Identifiers for ERICH4 Gene

  • GC19P041950

Summaries for ERICH4 Gene

GeneCards Summary for ERICH4 Gene

ERICH4 (Glutamate Rich 4) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for ERICH4 Gene

Genomics for ERICH4 Gene

Regulatory Elements for ERICH4 Gene

Enhancers for ERICH4 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH19F041542 1 Ensembl ENCODE 11.9 +99.4 99364 1.0 HDAC1 CTCF IRF2 ZBTB40 RAD21 ZNF316 POLR2A ZBTB48 ZNF143 SMC3 ATP5SL ERICH4 CEACAM21 GC19M041536 LINC01480
GH19F041545 1.2 FANTOM5 ENCODE 11.9 +103.2 103157 2.1 HDGF BCOR ZMYM3 ZNF335 CTBP1 GATA3 POLR2A SCRT2 EED ZNF143 ATP5SL ERICH4 LINC01480 ENSG00000268355 EXOSC5 PCAT19 CEACAM21 ARHGEF1 CD79A B9D2
GH19F041547 0.2 ENCODE 11.7 +109.6 109569 10.5 HDGF HDAC1 TBP CBX3 PKNOX1 WRNIP1 ZNF335 ELK1 SCRT2 ETV6 CEACAMP3 CEACAM21 ATP5SL ERICH4 BCKDHA EXOSC5 LINC01480 ENSG00000268355 TMEM91 ENSG00000259436
GH19F041529 1.2 FANTOM5 ENCODE 11.4 +88.3 88288 2.9 TBP PKNOX1 ATF1 KLF17 GLIS2 ZNF366 RCOR1 ETV6 CREM ZNF263 PCAT19 ATP5SL ERICH4 LINC01480 TGFB1 ARHGEF1 CCDC97 B9D2 CEACAM21 TMEM91
GH19F041528 0.2 Ensembl 11.4 +85.2 85243 0.8 PKNOX1 ZNF2 RAD21 ZNF335 GLIS2 ZNF366 ZNF143 EGR2 ZNF263 ZNF362 CEACAM21 ATP5SL ERICH4 LINC01480 ENSG00000268355 PLEKHA3P1
- Elite enhancer/Elite enhancer-gene association Download Table
Download GeneHancer data dump

Enhancers around ERICH4 on UCSC Golden Path with GeneCards custom track

Genomic Location for ERICH4 Gene

Chromosome:
19
Start:
41,443,158 bp from pter
End:
41,444,765 bp from pter
Size:
1,608 bases
Orientation:
Plus strand

Genomic View for ERICH4 Gene

Genes around ERICH4 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
ERICH4 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for ERICH4 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for ERICH4 Gene

Proteins for ERICH4 Gene

  • Protein details for ERICH4 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A6NGS2-ERIC4_HUMAN
    Recommended name:
    Glutamate-rich protein 4
    Protein Accession:
    A6NGS2

    Protein attributes for ERICH4 Gene

    Size:
    130 amino acids
    Molecular mass:
    14477 Da
    Quaternary structure:
    No Data Available

neXtProt entry for ERICH4 Gene

Post-translational modifications for ERICH4 Gene

No Post-translational modifications

Other Protein References for ERICH4 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for ERICH4 Gene

Domains & Families for ERICH4 Gene

Protein Domains for ERICH4 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with ERICH4: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for ERICH4 Gene

Function for ERICH4 Gene

Animal Model Products

Inhibitory RNA Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for ERICH4 Gene

Localization for ERICH4 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Gene Ontology (GO) - Cellular Components for ERICH4 Gene

Pathways & Interactions for ERICH4 Gene

SuperPathways for ERICH4 Gene

No Data Available

Interacting Proteins for ERICH4 Gene

Gene Ontology (GO) - Biological Process for ERICH4 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for ERICH4 Gene

Transcripts for ERICH4 Gene

mRNA/cDNA for ERICH4 Gene

(2) REFSEQ mRNAs :
(1) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Inhibitory RNA Products

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for ERICH4 Gene

No ASD Table

Relevant External Links for ERICH4 Gene

GeneLoc Exon Structure for
ERICH4
ECgene alternative splicing isoforms for
ERICH4

Expression for ERICH4 Gene

mRNA expression in normal human tissues for ERICH4 Gene

mRNA differential expression in normal tissues according to GTEx for ERICH4 Gene

This gene is overexpressed in Small Intestine - Terminal Ileum (x13.4) and Kidney - Cortex (x12.2).

NURSA nuclear receptor signaling pathways regulating expression of ERICH4 Gene:

ERICH4
genes like me logo Genes that share expression patterns with ERICH4: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners and mRNA Expression by UniProt/SwissProt for ERICH4 Gene

Orthologs for ERICH4 Gene

This gene was present in the common ancestor of mammals.

Orthologs for ERICH4 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia C19H19orf69 34
  • 99.67 (n)
C19orf69 35
  • 96 (a)
OneToOne
dog
(Canis familiaris)
Mammalia ERICH4 34
  • 80.51 (n)
C19orf69 35
  • 70 (a)
OneToOne
cow
(Bos Taurus)
Mammalia ERICH4 34
  • 77.18 (n)
C19orf69 35
  • 70 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia LOC685046 34
  • 74.62 (n)
mouse
(Mus musculus)
Mammalia Gm7092 34 35
  • 74.1 (n)
Erich4 16
Species where no ortholog for ERICH4 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for ERICH4 Gene

ENSEMBL:
Gene Tree for ERICH4 (if available)
TreeFam:
Gene Tree for ERICH4 (if available)

Paralogs for ERICH4 Gene

No data available for Paralogs for ERICH4 Gene

Variants for ERICH4 Gene

Sequence variations from dbSNP and Humsavar for ERICH4 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type
rs10415806 -- 41,443,569(+) GAGAC(G/T)GAGAG intron-variant
rs11083620 -- 41,442,778(+) AAGCT(A/G)TGGGC intron-variant, upstream-variant-2KB, utr-variant-5-prime
rs111375145 -- 41,444,575(+) CGGAC(A/G)CACAT intron-variant, utr-variant-3-prime
rs111840261 -- 41,444,078(+) CGCTG(C/T)GGGAG intron-variant, reference, missense
rs111950235 -- 41,444,924(+) CTCCT(-/G)GGTTC intron-variant, downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for ERICH4 Gene

Variant ID Type Subtype PubMed ID
esv3644380 CNV loss 21293372

Variation tolerance for ERICH4 Gene

Gene Damage Index Score: 3.09; 50.92% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for ERICH4 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
ERICH4

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for ERICH4 Gene

Disorders for ERICH4 Gene

Relevant External Links for ERICH4

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
ERICH4

No disorders were found for ERICH4 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for ERICH4 Gene

Publications for ERICH4 Gene

  1. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 3 4 64

Products for ERICH4 Gene

Sources for ERICH4 Gene

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